Thymic Function Associated With Cancer Development, Relapse, and Antitumor Immunity – A Mini-Review
出版年份 2020 全文链接
标题
Thymic Function Associated With Cancer Development, Relapse, and Antitumor Immunity – A Mini-Review
作者
关键词
-
出版物
Frontiers in Immunology
Volume 11, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2020-04-30
DOI
10.3389/fimmu.2020.00773
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- A conserved intratumoral regulatory T cell signature identifies 4-1BB as a pan-cancer target
- (2020) Zachary T. Freeman et al. JOURNAL OF CLINICAL INVESTIGATION
- Contributions of Age-Related Thymic Involution to Immunosenescence and Inflammaging
- (2020) Rachel Thomas et al. Immunity & Ageing
- Epigenetic control of Foxp3 in intratumoral T-cells regulates growth of hepatocellular carcinoma
- (2019) Qin Liu et al. Aging-US
- Pulling RANK on Cancer: Blocking Aire-Mediated Central Tolerance to Enhance Immunotherapy
- (2019) Maureen A. Su et al. Cancer Immunology Research
- The Pivotal Role of Regulatory T Cells in the Regulation of Innate Immune Cells
- (2019) Emeka B. Okeke et al. Frontiers in Immunology
- Programming for T-lymphocyte fates: modularity and mechanisms
- (2019) Ellen V. Rothenberg GENES & DEVELOPMENT
- The biology and functional importance of MAIT cells
- (2019) Dale I. Godfrey et al. NATURE IMMUNOLOGY
- Investigation of Antigen-Specific T-Cell Receptor Clusters in Human Cancers
- (2019) Hongyi Zhang et al. CLINICAL CANCER RESEARCH
- Impact of TCR Diversity on the Development of Transplanted or Chemically Induced Tumors
- (2019) Karin Schreiber et al. Cancer Immunology Research
- Harnessing NK Cells for Cancer Treatment
- (2019) Paola Minetto et al. Frontiers in Immunology
- Age and immunity: What is “immunosenescence”?
- (2018) Graham Pawelec EXPERIMENTAL GERONTOLOGY
- T cell senescence and CAR-T cell exhaustion in hematological malignancies
- (2018) Dimitri Kasakovski et al. Journal of Hematology & Oncology
- Atrophied Thymus, a Tumor reservoir for Harboring Melanoma Cells
- (2018) Olga Sizova et al. MOLECULAR CANCER RESEARCH
- Thymic involution and rising disease incidence with age
- (2018) Sam Palmer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Does patient age influence anti-cancer immunity?
- (2018) Graham Pawelec Seminars in Immunopathology
- Recent Advances in Targeting CD8 T-Cell Immunity for More Effective Cancer Immunotherapy
- (2018) Aurélie Durgeau et al. Frontiers in Immunology
- Immunosenescence and Inflamm-Aging As Two Sides of the Same Coin: Friends or Foes?
- (2018) Tamas Fulop et al. Frontiers in Immunology
- Anti-PD-1 and Anti-CTLA-4 Therapies in Cancer: Mechanisms of Action, Efficacy, and Limitations
- (2018) Judith A. Seidel et al. Frontiers in Oncology
- A comprehensive review on the role of co-signaling receptors and Treg homeostasis in autoimmunity and tumor immunity
- (2018) Prabhakaran Kumar et al. JOURNAL OF AUTOIMMUNITY
- Antigen-Specificity in the Thymic Development and Peripheral Activity of CD4+FOXP3+ T Regulatory Cells
- (2018) Jelka Pohar et al. Frontiers in Immunology
- Tumor-Intrinsic PD-L1 Signaling in Cancer Initiation, Development and Treatment: Beyond Immune Evasion
- (2018) Peixin Dong et al. Frontiers in Oncology
- CD8+ cytotoxic T lymphocytes in cancer immunotherapy: A review
- (2018) Bagher Farhood et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Physiologic Thymic Involution Underlies Age-Dependent Accumulation of Senescence-Associated CD4+T Cells
- (2017) Kyosuke Sato et al. JOURNAL OF IMMUNOLOGY
- Tumor immunotherapy: drug-induced neoantigens (xenogenization) and immune checkpoint inhibitors
- (2017) Ornella Franzese et al. Oncotarget
- Capacity of tTreg generation is not impaired in the atrophied thymus
- (2017) Jiyoung Oh et al. PLOS BIOLOGY
- Considerations for successful cancer immunotherapy in aged hosts
- (2016) V. Hurez et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- A senescence secretory switch mediated by PI3K/AKT/mTOR activation controls chemoprotective endothelial secretory responses
- (2016) Eric H. Bent et al. GENES & DEVELOPMENT
- Roles of regulatory T cells in cancer immunity
- (2016) Yoshiko Takeuchi et al. INTERNATIONAL IMMUNOLOGY
- Estrogen turns down “the AIRE”
- (2016) Pearl Bakhru et al. JOURNAL OF CLINICAL INVESTIGATION
- Estrogen-mediated downregulation of AIRE influences sexual dimorphism in autoimmune diseases
- (2016) Nadine Dragin et al. JOURNAL OF CLINICAL INVESTIGATION
- Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade
- (2016) N. McGranahan et al. SCIENCE
- The Journey from Discoveries in Fundamental Immunology to Cancer Immunotherapy
- (2015) Jacques F.A.P. Miller et al. CANCER CELL
- Fezf2 Orchestrates a Thymic Program of Self-Antigen Expression for Immune Tolerance
- (2015) Hiroyuki Takaba et al. CELL
- Manipulation of regulatory T cells and antigen-specific cytotoxic T lymphocyte-based tumour immunotherapy
- (2015) Shirin Karimi et al. IMMUNOLOGY
- Treg(s) in Cancer: Friends or Foe?
- (2015) Dominik Wolf et al. JOURNAL OF CELLULAR PHYSIOLOGY
- A CD153+CD4+T Follicular Cell Population with Cell-Senescence Features Plays a Crucial Role in Lupus Pathogenesis via Osteopontin Production
- (2015) Suhail Tahir et al. JOURNAL OF IMMUNOLOGY
- Thymic Involution Perturbs Negative Selection Leading to Autoreactive T Cells That Induce Chronic Inflammation
- (2015) Brandon D. Coder et al. JOURNAL OF IMMUNOLOGY
- IL-7 coordinates proliferation, differentiation and Tcra recombination during thymocyte β-selection
- (2015) Amine Boudil et al. NATURE IMMUNOLOGY
- Microenvironmental regulation of therapeutic response in cancer
- (2015) Florian Klemm et al. TRENDS IN CELL BIOLOGY
- Regulation of Bim in Health and Disease
- (2015) Ronit Vogt Sionov et al. Oncotarget
- Age and Cancer Risk
- (2014) Mary C. White et al. AMERICAN JOURNAL OF PREVENTIVE MEDICINE
- T Lymphocytes Restrain Spontaneous Metastases in Permanent Dormancy
- (2014) I. Romero et al. CANCER RESEARCH
- Molecular Pathways: Niches in Metastatic Dormancy
- (2014) K. Yumoto et al. CLINICAL CANCER RESEARCH
- Phenotypic alterations, clinical impact and therapeutic potential of regulatory T cells in cancer
- (2014) Belal Chaudhary et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Enhancement of an anti-tumor immune response by transient blockade of central T cell tolerance
- (2014) Imran S. Khan et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The Programmed Death-1 Immune-Suppressive Pathway: Barrier to Antitumor Immunity
- (2014) Suzanne Ostrand-Rosenberg et al. JOURNAL OF IMMUNOLOGY
- Breaking through the central tolerance ceiling to unleash anticancer immune responses
- (2014) Maureen A Su et al. OncoImmunology
- Aging is associated with increased regulatory T-cell function
- (2013) Sanjay K. Garg et al. AGING CELL
- A Novel Model of Dormancy for Bone Metastatic Breast Cancer Cells
- (2013) R. Marlow et al. CANCER RESEARCH
- Aire Deficiency Promotes TRP-1-Specific Immune Rejection of Melanoma
- (2013) M.-L. Zhu et al. CANCER RESEARCH
- Mechanisms Governing Metastatic Dormancy and Reactivation
- (2013) Filippo G. Giancotti CELL
- The perivascular niche regulates breast tumour dormancy
- (2013) Cyrus M. Ghajar et al. NATURE CELL BIOLOGY
- Aire-Dependent Thymic Development of Tumor-Associated Regulatory T Cells
- (2013) S. Malchow et al. SCIENCE
- Disruption of the Thymic Microenvironment Is Associated with Thymic Involution of Transitional Cell Cancer
- (2013) Yan Song et al. UROLOGIA INTERNATIONALIS
- The Impact of Aging on Regulatory T-Cells
- (2013) Johannes Fessler et al. Frontiers in Immunology
- The Effect of Age on Thymic Function
- (2013) Donald B. Palmer Frontiers in Immunology
- Organ-specific regulatory T cells of thymic origin are expanded in murine prostate tumors
- (2013) Sven Malchow et al. OncoImmunology
- Homeostasis and function of regulatory T cells in aging
- (2012) Jana Raynor et al. CURRENT OPINION IN IMMUNOLOGY
- Thymic epithelial cells: antigen presenting cells that regulate T cell repertoire and tolerance development
- (2012) Konstantina Alexandropoulos et al. IMMUNOLOGIC RESEARCH
- Treatment-induced damage to the tumor microenvironment promotes prostate cancer therapy resistance through WNT16B
- (2012) Yu Sun et al. NATURE MEDICINE
- The Immune Response to Melanoma Is Limited by Thymic Selection of Self-Antigens
- (2012) Ulrike Träger et al. PLoS One
- Mechanisms of T Cell Development and Transformation
- (2011) Ute Koch et al. Annual Review of Cell and Developmental Biology
- Circulating Tumor Cells and Circulating Tumor DNA
- (2011) Catherine Alix-Panabières et al. Annual Review of Medicine
- CD8+ cytotoxic T cell and FOXP3+ regulatory T cell infiltration in relation to breast cancer survival and molecular subtypes
- (2011) Fangfang Liu et al. BREAST CANCER RESEARCH AND TREATMENT
- Thymus-derived rather than tumor-induced regulatory T cells predominate in brain tumors
- (2011) Derek A. Wainwright et al. NEURO-ONCOLOGY
- Analysis of the T-Cell Receptor Repertoires of Tumor-Infiltrating Conventional and Regulatory T Cells Reveals No Evidence for Conversion in Carcinogen-Induced Tumors
- (2010) J. P. Hindley et al. CANCER RESEARCH
- DNA Damage-Mediated Induction of a Chemoresistant Niche
- (2010) Luke A. Gilbert et al. CELL
- Framework models of tumor dormancy from patient-derived observations
- (2010) Christoph A Klein CURRENT OPINION IN GENETICS & DEVELOPMENT
- αβ versus γδ lineage choice at the first TCR-controlled checkpoint
- (2010) Taras Kreslavsky et al. CURRENT OPINION IN IMMUNOLOGY
- Regulatory T-cell differentiation versus clonal deletion of autoreactive thymocytes
- (2010) Gerald Wirnsberger et al. IMMUNOLOGY AND CELL BIOLOGY
- Regulatory T cells in tumor immunity
- (2010) Hiroyoshi Nishikawa et al. INTERNATIONAL JOURNAL OF CANCER
- Tumor-induced thymic atrophy: Alteration in interferons and Jak/Stats signaling pathways
- (2010) Lopez INTERNATIONAL JOURNAL OF ONCOLOGY
- Bim Dictates Naive CD4 T Cell Lifespan and the Development of Age-Associated Functional Defects
- (2010) H. Tsukamoto et al. JOURNAL OF IMMUNOLOGY
- A Major Role for Bim in Regulatory T Cell Homeostasis
- (2010) C. A. Chougnet et al. JOURNAL OF IMMUNOLOGY
- Autonomous role of medullary thymic epithelial cells in central CD4+ T cell tolerance
- (2010) Maria Hinterberger et al. NATURE IMMUNOLOGY
- The role of AIRE in human autoimmune disease
- (2010) Eitan M. Akirav et al. Nature Reviews Endocrinology
- Circulating tumour cells in cancer patients: challenges and perspectives
- (2010) Klaus Pantel et al. TRENDS IN MOLECULAR MEDICINE
- Denosumab for Prevention of Fractures in Postmenopausal Women with Osteoporosis
- (2009) Steven R. Cummings et al. NEW ENGLAND JOURNAL OF MEDICINE
- PD-1+ memory phenotype CD4+ T cells expressing C/EBP underlie T cell immunodepression in senescence and leukemia
- (2009) K. Shimatani et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Age-associated increase in lifespan of naive CD4 T cells contributes to T-cell homeostasis but facilitates development of functional defects
- (2009) H. Tsukamoto et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- CD28− T cells: their role in the age-associated decline of immune function
- (2009) Nan-ping Weng et al. TRENDS IN IMMUNOLOGY
- Epstein-Barr Virus Latency in B Cells Leads to Epigenetic Repression and CpG Methylation of the Tumour Suppressor Gene Bim
- (2009) Kostas Paschos et al. PLoS Pathogens
- Regulatory T cells and treatment of cancer
- (2008) Tyler J Curiel CURRENT OPINION IN IMMUNOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started