标题
T cell senescence and CAR-T cell exhaustion in hematological malignancies
作者
关键词
T cells, Senescence, Hematological malignancy, T cell activation, CAR-T cells
出版物
Journal of Hematology & Oncology
Volume 11, Issue 1, Pages -
出版商
Springer Nature
发表日期
2018-07-04
DOI
10.1186/s13045-018-0629-x
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- T-cell Immunoglobulin and ITIM Domain Contributes to CD8+ T-cell Immunosenescence
- (2018) Yangzi Song et al. AGING CELL
- Engineering chimeric antigen receptor-T cells for cancer treatment
- (2018) Baixin Ye et al. Molecular Cancer
- Regulatory T cells trigger effector T cell DNA damage and senescence caused by metabolic competition
- (2018) Xia Liu et al. Nature Communications
- Markers of T Cell Senescence in Humans
- (2017) Weili Xu et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Recent developments in immunotherapy of acute myeloid leukemia
- (2017) Felix S. Lichtenegger et al. Journal of Hematology & Oncology
- Interleukin-21 promotes thymopoiesis recovery following hematopoietic stem cell transplantation
- (2017) Aurélie Tormo et al. Journal of Hematology & Oncology
- Recent advances in cancer immunotherapy
- (2017) Weijing Sun Journal of Hematology & Oncology
- Blimp-1 impairs T cell function via upregulation of TIGIT and PD-1 in patients with acute myeloid leukemia
- (2017) Liuluan Zhu et al. Journal of Hematology & Oncology
- Long-term immune reconstitution and T cell repertoire analysis after autologous hematopoietic stem cell transplantation in systemic sclerosis patients
- (2017) Dominique Farge et al. Journal of Hematology & Oncology
- Immunotherapy in hematologic malignancies: past, present, and future
- (2017) Annie Im et al. Journal of Hematology & Oncology
- Intrathymic injection of hematopoietic progenitor cells establishes functional T cell development in a mouse model of severe combined immunodeficiency
- (2017) Andrea Z. Tuckett et al. Journal of Hematology & Oncology
- Chimeric antigen receptors for adoptive T cell therapy in acute myeloid leukemia
- (2017) Mingxue Fan et al. Journal of Hematology & Oncology
- Chimeric antigen receptor T cells: a novel therapy for solid tumors
- (2017) Shengnan Yu et al. Journal of Hematology & Oncology
- Frontline Science: Functionally impaired geriatric CAR-T cells rescued by increased α5β1 integrin expression
- (2017) Prajna Guha et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Immunology: The chronicles of T-cell exhaustion
- (2017) Robert A. Amezquita et al. NATURE
- TCR engagement negatively affects CD8 but not CD4 CAR T cell expansion and leukemic clearance
- (2017) Yinmeng Yang et al. Science Translational Medicine
- Perturbed CD8+ T cell TIGIT/CD226/PVR axis despite early initiation of antiretroviral treatment in HIV infected individuals
- (2017) Johanna Tauriainen et al. Scientific Reports
- Tonic 4-1BB Costimulation in Chimeric Antigen Receptors Impedes T Cell Survival and Is Vector-Dependent
- (2017) Diogo Gomes-Silva et al. Cell Reports
- Intratumoral FOXP3+ Regulatory T Cells in Diffuse Large B-Cell Lymphoma
- (2017) Marwa M. Serag El-Dien et al. APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY
- The Dual Role of Cellular Senescence in Developing Tumors and Their Response to Cancer Therapy
- (2017) Markus Schosserer et al. Frontiers in Oncology
- Interleukin-21 administration to aged mice rejuvenates their peripheral T-cell pool by triggeringde novothymopoiesis
- (2016) E. Al-Chami et al. AGING CELL
- Cellular senescence impact on immune cell fate and function
- (2016) Rita Vicente et al. AGING CELL
- Markers of cellular senescence. Telomere shortening as a marker of cellular senescence
- (2016) Alexandra Bernadotte et al. Aging-US
- Approaches to augment CAR T-cell therapy by targeting the apoptotic machinery
- (2016) Hannah Karlsson BIOCHEMICAL SOCIETY TRANSACTIONS
- Human CAR T cells with cell-intrinsic PD-1 checkpoint blockade resist tumor-mediated inhibition
- (2016) Leonid Cherkassky et al. JOURNAL OF CLINICAL INVESTIGATION
- Driving an improved CAR for cancer immunotherapy
- (2016) Xiaopei Huang et al. JOURNAL OF CLINICAL INVESTIGATION
- T cells in multiple myeloma display features of exhaustion and senescence at the tumor site
- (2016) Claudia Zelle-Rieser et al. Journal of Hematology & Oncology
- Multiple myeloma causes clonal T-cell immunosenescence: identification of potential novel targets for promoting tumour immunity and implications for checkpoint blockade
- (2016) H Suen et al. LEUKEMIA
- Reprogramming away from the exhausted T cell state
- (2016) Peter Karagiannis et al. SEMINARS IN IMMUNOLOGY
- TIGIT Marks Exhausted T Cells, Correlates with Disease Progression, and Serves as a Target for Immune Restoration in HIV and SIV Infection
- (2016) Glen M. Chew et al. PLoS Pathogens
- The Immune System in Cancer Prevention, Development and Therapy
- (2015) Serge M. Candeias et al. Anti-Cancer Agents in Medicinal Chemistry
- Autologous stem cell transplantation aids autoimmune patients by functional renewal and TCR diversification of regulatory T cells
- (2015) E. M. Delemarre et al. BLOOD
- Analysis of CD8+ Treg cells in patients with ovarian cancer: a possible mechanism for immune impairment
- (2015) Shuping Zhang et al. Cellular & Molecular Immunology
- Increased regulatory T cells in acute lymphoblastic leukemia patients
- (2015) Siti-Zuleha Idris et al. Hematology
- Bioengineering Thymus Organoids to Restore Thymic Function and Induce Donor-Specific Immune Tolerance to Allografts
- (2015) Yong Fan et al. MOLECULAR THERAPY
- 4-1BB costimulation ameliorates T cell exhaustion induced by tonic signaling of chimeric antigen receptors
- (2015) Adrienne H Long et al. NATURE MEDICINE
- Immune Modulation in Hematologic Malignancies
- (2015) Madhav V. Dhodapkar et al. SEMINARS IN ONCOLOGY
- Prognostic value of tumor-infiltrating FoxP3+ regulatory T cells in cancers: a systematic review and meta-analysis
- (2015) Bin Shang et al. Scientific Reports
- Accumulation Mechanisms of CD4+CD25+FOXP3+ Regulatory T Cells in EBV-associated Gastric Carcinoma
- (2015) Na-na Zhang et al. Scientific Reports
- T-cell Exhaustion in Multiple Myeloma Relapse after Autotransplant: Optimal Timing of Immunotherapy
- (2015) D. J. Chung et al. Cancer Immunology Research
- Controlling T cell senescence in the tumor microenvironment for tumor immunotherapy
- (2015) Jian Ye et al. OncoImmunology
- CD28 Negative T Cells: Is Their Loss Our Gain?
- (2014) D. Mou et al. AMERICAN JOURNAL OF TRANSPLANTATION
- Lymphocyte Subset Recovery and Outcome after Autologous Hematopoietic Stem Cell Transplantation for Plasma Cell Myeloma
- (2014) Jessica Rueff et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- The role of the thymus in T-cell immune reconstitution after umbilical cord blood transplantation
- (2014) I. Politikos et al. BLOOD
- TLR8 signaling enhances tumor immunity by preventing tumor-induced T-cell senescence
- (2014) J. Ye et al. EMBO Molecular Medicine
- New advances in CMV and immunosenescence
- (2014) Paolo Sansoni et al. EXPERIMENTAL GERONTOLOGY
- The role of senescent cells in ageing
- (2014) Jan M. van Deursen NATURE
- The kinase p38 activated by the metabolic regulator AMPK and scaffold TAB1 drives the senescence of human T cells
- (2014) Alessio Lanna et al. NATURE IMMUNOLOGY
- Reprogramming antitumor immunity
- (2014) Joseph G. Crompton et al. TRENDS IN IMMUNOLOGY
- Generation of Rejuvenated Antigen-Specific T Cells by Reprogramming to Pluripotency and Redifferentiation
- (2013) Toshinobu Nishimura et al. Cell Stem Cell
- T cell anergy, exhaustion, senescence, and stemness in the tumor microenvironment
- (2013) Joel Crespo et al. CURRENT OPINION IN IMMUNOLOGY
- Control of inflammation by integration of environmental cues by regulatory T cells
- (2013) Ashutosh Chaudhry et al. JOURNAL OF CLINICAL INVESTIGATION
- IFN- Inhibits Telomerase in Human CD8+ T Cells by Both hTERT Downregulation and Induction of p38 MAPK Signaling
- (2013) A. Lanna et al. JOURNAL OF IMMUNOLOGY
- Generation of tumor-targeted human T lymphocytes from induced pluripotent stem cells for cancer therapy
- (2013) Maria Themeli et al. NATURE BIOTECHNOLOGY
- Brief Report: Autologous Stem Cell Transplantation Restores Immune Tolerance in Experimental Arthritis by Renewal and Modulation of the Teff Cell Compartment
- (2013) Eveline M. Delemarre et al. Arthritis & Rheumatology
- Reversing T cell immunosenescence: why, who, and how
- (2012) Pierre Olivier Lang et al. AGE
- Human regulatory T cells induce T-lymphocyte senescence
- (2012) J. Ye et al. BLOOD
- Telomere length and iPSC re-programming: survival of the longest
- (2012) Richard Allsopp CELL RESEARCH
- The three main stumbling blocks for anticancer T cells
- (2012) Lukas Baitsch et al. TRENDS IN IMMUNOLOGY
- CMV and Immunosenescence: from basics to clinics
- (2012) Rafael Solana et al. Immunity & Ageing
- Regulatory T cells in acute myelogenous leukemia: is it time for immunomodulation?
- (2011) C. Ustun et al. BLOOD
- Both CD4+ FoxP3+ and CD4+ FoxP3− T cells from patients with B-cell malignancy express cytolytic markers and kill autologous leukaemic B cells in vitro
- (2011) Camilla A. Lindqvist et al. IMMUNOLOGY
- T regulatory cells in B-cell malignancy - tumour support or kiss of death?
- (2011) Camilla A. Lindqvist et al. IMMUNOLOGY
- T cell exhaustion
- (2011) E John Wherry NATURE IMMUNOLOGY
- Immunophenotype and increased presence of CD4+CD25+ regulatory T cells in patients with acute lymphoblastic leukemia
- (2011) CUI-PING WU et al. Oncology Letters
- Induction of T cell anergy: integration of environmental cues and infectious tolerance
- (2010) Pascal Chappert et al. CURRENT OPINION IN IMMUNOLOGY
- Expression ofp16INK4ain peripheral blood T-cells is a biomarker of human aging
- (2009) Yan Liu et al. AGING CELL
- The tumor microenvironment and its role in promoting tumor growth
- (2008) T L Whiteside ONCOGENE
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started