Histone Deacetylases Inhibitors in Neurodegenerative Diseases, Neuroprotection and Neuronal Differentiation
出版年份 2020 全文链接
标题
Histone Deacetylases Inhibitors in Neurodegenerative Diseases, Neuroprotection and Neuronal Differentiation
作者
关键词
-
出版物
Frontiers in Pharmacology
Volume 11, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2020-04-24
DOI
10.3389/fphar.2020.00537
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Tacrine-hydroxamate Derivatives as Multitarget-Directed Ligands for the Treatment of Alzheimer’s Disease: Design, Synthesis, and Biological Evaluation
- (2020) Ana Xu et al. BIOORGANIC CHEMISTRY
- Depending on the stress, histone deacetylase inhibitors act as heat shock protein co-inducers in motor neurons and potentiate arimoclomol, exerting neuroprotection through multiple mechanisms in ALS models
- (2020) Rachel Kuta et al. CELL STRESS & CHAPERONES
- An Antisense Oligonucleotide Leads to Suppressed Transcription of Hdac2 and Long-Term Memory Enhancement
- (2020) Shane G. Poplawski et al. Molecular Therapy-Nucleic Acids
- Protective effects of valproic acid on 6‐hydroxydopamine‐induced neuroinjury
- (2020) Shih‐Wei Hsu et al. ENVIRONMENTAL TOXICOLOGY
- Synthesis and biological evaluation of acridine-based histone deacetylase inhibitors as multitarget agents against Alzheimer’s disease
- (2020) Hui-Ju Tseng et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Nusinersen in adults with 5q spinal muscular atrophy: a non-interventional, multicentre, observational cohort study
- (2020) Tim Hagenacker et al. LANCET NEUROLOGY
- Histone deacetylase 4 protects from denervation and skeletal muscle atrophy in a murine model of amyotrophic lateral sclerosis
- (2019) Eva Pigna et al. EBioMedicine
- Hdac4 interactions in Huntington’s Disease viewed through the prism of multiomics
- (2019) Joel D Federspiel et al. MOLECULAR & CELLULAR PROTEOMICS
- Taking Advantage of the Selectivity of Histone Deacetylases and Phosphodiesterase Inhibitors to Design Better Therapeutic Strategies to Treat Alzheimer’s Disease
- (2019) Mar Cuadrado-Tejedor et al. Frontiers in Aging Neuroscience
- Pan-HDAC Inhibitors Promote Tau Aggregation by Increasing the Level of Acetylated Tau
- (2019) Hyeanjeong Jeong et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Combined treatment with the histone deacetylase inhibitor LBH589 and a splice‐switch antisense oligonucleotide enhances SMN2 splicing and SMN expression in Spinal Muscular Atrophy cells
- (2019) Vittoria Pagliarini et al. JOURNAL OF NEUROCHEMISTRY
- Molecular Factors Involved in Spinal Muscular Atrophy Pathways as Possible Disease-modifying Candidates
- (2018) Marianna A. Maretina et al. CURRENT GENOMICS
- Impaired Mitophagy and Protein Acetylation Levels in Fibroblasts from Parkinson’s Disease Patients
- (2018) Sokhna M. S. Yakhine-Diop et al. MOLECULAR NEUROBIOLOGY
- Upregulation of histone deacetylase 2 in laser capture nigral microglia in Parkinson's disease
- (2018) Yuyan Tan et al. NEUROBIOLOGY OF AGING
- Recent studies on cellular and molecular mechanisms in Alzheimer’s disease: focus on epigenetic factors and histone deacetylase
- (2018) Harikesh Dubey et al. REVIEWS IN THE NEUROSCIENCES
- Molecular Pathogenesis in Huntington’s Disease
- (2018) S. N. Illarioshkin et al. BIOCHEMISTRY-MOSCOW
- Loss of HDAC5 Impairs Memory Function: Implications for Alzheimer's Disease
- (2018) Roberto Carlos Agis-Balboa et al. JOURNAL OF ALZHEIMERS DISEASE
- Tubastatin A/ACY-1215 Improves Cognition in Alzheimer's Disease Transgenic Mice
- (2018) Ling Zhang et al. JOURNAL OF ALZHEIMERS DISEASE
- The Histone Deacetylase Inhibitor Nicotinamide Exacerbates Neurodegeneration in the Lactacystin Rat Model of Parkinson's Disease
- (2018) Ian F Harrison et al. JOURNAL OF NEUROCHEMISTRY
- Histone Deacetylase Inhibitors: A Therapeutic Key in Neurological Disorders?
- (2018) Malgorzata Ziemka-Nalecz et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- HDAC2 dysregulation in the nucleus basalis of Meynert during the progression of Alzheimer's disease
- (2018) Laura Mahady et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Early postnatal behavioral, cellular, and molecular changes in models of Huntington disease are reversible by HDAC inhibition
- (2018) Florian A. Siebzehnrübl et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Histone deacetylase inhibitors in hepatocellular carcinoma: A therapeutic perspective
- (2018) Diamantis I. Tsilimigras et al. SURGICAL ONCOLOGY-OXFORD
- Discovery of in Vivo Chemical Probes for Treating Alzheimer’s Disease: Dual Phosphodiesterase 5 (PDE5) and Class I Histone Deacetylase Selective Inhibitors
- (2018) Obdulia Rabal et al. ACS Chemical Neuroscience
- Epigenetics in amyotrophic lateral sclerosis: a role for histone post-translational modifications in neurodegenerative disease
- (2018) Seth A. Bennett et al. Translational Research
- Increased Post-Translational Lysine Acetylation of Myelin Basic Protein Is Associated with Peak Neurological Disability in a Mouse Experimental Autoimmune Encephalomyelitis Model of Multiple Sclerosis
- (2017) Ryan Lillico et al. JOURNAL OF PROTEOME RESEARCH
- Laquinimod treatment in the R6/2 mouse model
- (2017) Gisa Ellrichmann et al. Scientific Reports
- The development prospection of HDAC inhibitors as a potential therapeutic direction in Alzheimer’s disease
- (2017) Shuang-shuang Yang et al. Translational Neurodegeneration
- Impact of Scaffold Exploration on Novel Dual-Acting Histone Deacetylases and Phosphodiesterase 5 Inhibitors for the Treatment of Alzheimer’s Disease
- (2016) Juan A. Sánchez-Arias et al. ACS Chemical Neuroscience
- Protective effects of butyrate-based compounds on a mouse model for spinal muscular atrophy
- (2016) Matthew E.R. Butchbach et al. EXPERIMENTAL NEUROLOGY
- Design, Synthesis, and Biological Evaluation of First-in-Class Dual Acting Histone Deacetylases (HDACs) and Phosphodiesterase 5 (PDE5) Inhibitors for the Treatment of Alzheimer’s Disease
- (2016) Obdulia Rabal et al. JOURNAL OF MEDICINAL CHEMISTRY
- Mechanism for neurotropic action of vorinostat, a pan histone deacetylase inhibitor
- (2016) Surabhi Shukla et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- The Epigenome as a therapeutic target for Parkinson's disease
- (2016) ShaneV Hegarty et al. Neural Regeneration Research
- A novel histone deacetylase 1 and 2 isoform-specific inhibitor alleviates experimental Parkinson's disease
- (2016) Chi-Jing Choong et al. NEUROBIOLOGY OF AGING
- A Small Molecule Activator of p300/CBP Histone Acetyltransferase Promotes Survival and Neurite Growth in a Cellular Model of Parkinson’s Disease
- (2016) Shane V. Hegarty et al. NEUROTOXICITY RESEARCH
- Pharmacological modulation of HDAC1 and HDAC6 in vivo in a zebrafish model: Therapeutic implications for Parkinson’s disease
- (2016) Brígida R. Pinho et al. PHARMACOLOGICAL RESEARCH
- Histone acetyltransferases: challenges in targeting bi-substrate enzymes
- (2016) Hannah Wapenaar et al. Clinical Epigenetics
- The Effects of Pharmacological Inhibition of Histone Deacetylase 3 (HDAC3) in Huntington’s Disease Mice
- (2016) Haiqun Jia et al. PLoS One
- Neurorestoration induced by the HDAC inhibitor sodium valproate in the lactacystin model of Parkinson's is associated with histone acetylation and up-regulation of neurotrophic factors
- (2015) Ian F Harrison et al. BRITISH JOURNAL OF PHARMACOLOGY
- NRSF is an essential mediator for the neuroprotection of trichostatin A in the MPTP mouse model of Parkinson's disease
- (2015) Haiyun Suo et al. NEUROPHARMACOLOGY
- Transcriptional dysregulation in Huntington’s disease: The role of histone deacetylases
- (2015) Sorabh Sharma et al. PHARMACOLOGICAL RESEARCH
- Targeting Histone Deacetylases: A Novel Approach in Parkinson’s Disease
- (2015) Sorabh Sharma et al. Parkinsons Disease
- Induction of Neurotrophic and Differentiation Factors in Neural Stem Cells by Valproic Acid
- (2014) Walaa Almutawaa et al. BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY
- Effects of histone deacetylase inhibition on the survival, proliferation and migration of Schwann cells, as well as on the expression of neurotrophic factors and genes associated with myelination
- (2014) YAZHOU WANG et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Age-dependent effects of valproic acid in Alzheimer’s disease (AD) mice are associated with nerve growth factor (NGF) regulation
- (2014) H. Noh et al. NEUROSCIENCE
- The histone deacetylase inhibitor trichostatin A induces neurite outgrowth in PC12 cells via the epigenetically regulated expression of the nur77 gene
- (2014) Takuma Tomioka et al. NEUROSCIENCE RESEARCH
- Histone deacetylase activity and brain-derived neurotrophic factor (BDNF) levels in a pharmacological model of mania
- (2014) Laura Stertz et al. REVISTA BRASILEIRA DE PSIQUIATRIA
- Muscle histone deacetylase 4 upregulation in amyotrophic lateral sclerosis: potential role in reinnervation ability and disease progression
- (2013) Gaëlle Bruneteau et al. BRAIN
- Histone deacetylase inhibitors as potential treatment for spinal muscular atrophy
- (2013) Jafar Mohseni et al. GENETICS AND MOLECULAR BIOLOGY
- The mood stabilizer valproate activates humanFGF1gene promoter through inhibiting HDAC and GSK-3 activities
- (2013) Chien-Yu Kao et al. JOURNAL OF NEUROCHEMISTRY
- The Histone Deacetylase Inhibitor Sodium Butyrate Promotes Cell Death and Differentiation and Reduces Neurosphere Formation in Human Medulloblastoma Cells
- (2013) Carolina Nör et al. MOLECULAR NEUROBIOLOGY
- Histone deacetylase inhibition leads to neuroprotection through regulation on glial function
- (2013) Xuefei Wu et al. Molecular Neurodegeneration
- Small-molecule modulation of neurotrophin receptors: a strategy for the treatment of neurological disease
- (2013) Frank M. Longo et al. NATURE REVIEWS DRUG DISCOVERY
- Effect of HDAC Inhibitors on Neuroprotection and Neurite Outgrowth in Primary Rat Cortical Neurons Following Ischemic Insult
- (2013) Mohammad Rakibul Hasan et al. NEUROCHEMICAL RESEARCH
- Differential regulation of Bdnf expression in cortical neurons by class-selective histone deacetylase inhibitors
- (2013) Indrek Koppel et al. NEUROPHARMACOLOGY
- Valproic acid promotes neuronal differentiation by induction of neuroprogenitors in human bone-marrow mesenchymal stromal cells
- (2013) Sin-Gu Jeong et al. NEUROSCIENCE LETTERS
- Epigenetic targeting of histone deacetylase: Therapeutic potential in Parkinson's disease?
- (2013) Ian F. Harrison et al. PHARMACOLOGY & THERAPEUTICS
- Proteomic Analysis Reveals Differentially Regulated Protein Acetylation in Human Amyotrophic Lateral Sclerosis Spinal Cord
- (2013) Dong Liu et al. PLoS One
- Histone deacetylase inhibitors are neuroprotective and preserve NGF-mediated cell survival following traumatic brain injury
- (2013) J. Lu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Novel small molecule activators of the Trk family of receptor tyrosine kinases
- (2012) Obiamaka Obianyo et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- The HAT/HDAC interplay: Multilevel control of STAT signaling
- (2012) Laura Icardi et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Reducing HDAC6 ameliorates cognitive deficits in a mouse model for Alzheimer's disease
- (2012) Nambirajan Govindarajan et al. EMBO Molecular Medicine
- The histone deacetylase inhibitor suberoylanilide hydroxamic acid attenuates human astrocyte neurotoxicity induced by interferon-γ
- (2012) Sadayuki Hashioka et al. Journal of Neuroinflammation
- Valproate promotes survival of retinal ganglion cells in a rat model of optic nerve crush
- (2012) Z.Z. Zhang et al. NEUROSCIENCE
- Genome-Wide Histone Acetylation Is Altered in a Transgenic Mouse Model of Huntington's Disease
- (2012) Karen N. McFarland et al. PLoS One
- Epigenetic histone acetylation and deacetylation mechanisms in experimental models of neurodegenerative disorders
- (2012) Zacharoula Konsoula et al. JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS
- Histone Deacetylase Inhibitors in Cell Pluripotency, Differentiation, and Reprogramming
- (2012) Androniki Kretsovali et al. Stem Cells International
- Differential regulation of the SMN2 gene by individual HDAC proteins
- (2011) Matthew C. Evans et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Neuroregeneration in neurodegenerative disorders
- (2011) Ana M Enciu et al. BMC Neurology
- Histone deacetylase inhibitors SAHA and sodium butyrate block G1-to-S cell cycle progression in neurosphere formation by adult subventricular cells
- (2011) Qiong Zhou et al. BMC NEUROSCIENCE
- Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, protects dopaminergic neurons from neurotoxin-induced damage
- (2011) SH Chen et al. BRITISH JOURNAL OF PHARMACOLOGY
- Regulation of chromatin by histone modifications
- (2011) Andrew J Bannister et al. CELL RESEARCH
- Treatment with trichostatin A initiated after disease onset delays disease progression and increases survival in a mouse model of amyotrophic lateral sclerosis
- (2011) Young-Eun Yoo et al. EXPERIMENTAL NEUROLOGY
- Low-molecular-weight compounds having neurotrophic activity in cultured PC12 cells and neurons
- (2011) H. Maruoka et al. JOURNAL OF BIOCHEMISTRY
- Histone Deacetylases in Neural Stem Cells and Induced Pluripotent Stem Cells
- (2011) Guoqiang Sun et al. JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY
- HDAC6 regulates aggresome-autophagy degradation pathway of α-synuclein in response to MPP+-induced stress
- (2011) Min Su et al. JOURNAL OF NEUROCHEMISTRY
- HDAC6 α-tubulin deacetylase: A potential therapeutic target in neurodegenerative diseases
- (2011) Guoyi Li et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Unknown
- (2011) Giuseppe Faraco et al. MOLECULAR MEDICINE
- Targeting HDACs: A Promising Therapy for Alzheimer's Disease
- (2011) Ke Xu et al. Oxidative Medicine and Cellular Longevity
- HDAC inhibition promotes neuronal outgrowth and counteracts growth cone collapse through CBP/p300 and P/CAF-dependent p53 acetylation
- (2010) P Gaub et al. CELL DEATH AND DIFFERENTIATION
- The clinical development of histone deacetylase inhibitors as targeted anticancer drugs
- (2010) Paul A Marks EXPERT OPINION ON INVESTIGATIONAL DRUGS
- SAHA ameliorates the SMA phenotype in two mouse models for spinal muscular atrophy
- (2010) Markus Riessland et al. HUMAN MOLECULAR GENETICS
- The Tale of Protein Lysine Acetylation in the Cytoplasm
- (2010) Karin Sadoul et al. JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY
- Differential Histone Deacetylase mRNA Expression Patterns in Amyotrophic Lateral Sclerosis
- (2010) Claas Janssen et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Irradiation with heavy-ion particles changes the cellular distribution of human histone acetyltransferase HAT1
- (2010) Emily A. Lebel et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- Drosophila Histone Deacetylase 6 Protects Dopaminergic Neurons against α-Synuclein Toxicity by Promoting Inclusion Formation
- (2010) Guiping Du et al. MOLECULAR BIOLOGY OF THE CELL
- Regulation of Cellular Metabolism by Protein Lysine Acetylation
- (2010) S. Zhao et al. SCIENCE
- Inhibition of Histone Deacetylases: A Pharmacological Approach to the Treatment of Non-Cancer Disorders
- (2009) Norbert Wiech et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Epigenetic reprogramming and induced pluripotency
- (2009) K. Hochedlinger et al. DEVELOPMENT
- Histone acetyl transferases as emerging drug targets
- (2009) Frank J. Dekker et al. DRUG DISCOVERY TODAY
- Trichostatin A Stimulates Steroid 5α-Reductase Gene Expression in Rat C6 Glioma Cells via a Mechanism Involving Sp1 and Sp3 Transcription Factors
- (2009) Song Her et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- The HDAC inhibitor, sodium butyrate, stimulates neurogenesis in the ischemic brain
- (2009) Hyeon Ju Kim et al. JOURNAL OF NEUROCHEMISTRY
- HDAC2 negatively regulates memory formation and synaptic plasticity
- (2009) Ji-Song Guan et al. NATURE
- Phenylbutyrate Ameliorates Cognitive Deficit and Reduces Tau Pathology in an Alzheimer's Disease Mouse Model
- (2009) Ana Ricobaraza et al. NEUROPSYCHOPHARMACOLOGY
- Inhibitors of Class 1 Histone Deacetylases Reverse Contextual Memory Deficits in a Mouse Model of Alzheimer's Disease
- (2009) Mark Kilgore et al. NEUROPSYCHOPHARMACOLOGY
- Histone deactylase inhibition combined with behavioral therapy enhances learning and memory following traumatic brain injury
- (2009) P.K. Dash et al. NEUROSCIENCE
- HDAC inhibitor trichostatin A-inhibited survival of dopaminergic neuronal cells
- (2009) Yong Wang et al. NEUROSCIENCE LETTERS
- Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions
- (2009) C. Choudhary et al. SCIENCE
- Multiple roles of HDAC inhibition in neurodegenerative conditions
- (2009) De-Maw Chuang et al. TRENDS IN NEUROSCIENCES
- Combined riluzole and sodium phenylbutyrate therapy in transgenic amyotrophic lateral sclerosis mice
- (2008) Steven J. Del Signore et al. Amyotrophic Lateral Sclerosis
- Determination of the class and isoform selectivity of small-molecule histone deacetylase inhibitors
- (2008) Nagma Khan et al. BIOCHEMICAL JOURNAL
- Valproic acid induces differentiation and inhibition of proliferation in neural progenitor cells via the beta-catenin-Ras-ERK-p21Cip/WAF1 pathway
- (2008) Gyung-Ah Jung et al. BMC CELL BIOLOGY
- Catalysis and substrate selection by histone/protein lysine acetyltransferases
- (2008) Christopher E Berndsen et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Isoform-Selective Histone Deacetylase Inhibitors
- (2008) Takayoshi Suzuki et al. CURRENT PHARMACEUTICAL DESIGN
- Histone deacetylases 1 and 2 are expressed at distinct stages of neuro-glial development
- (2008) Jessica L. MacDonald et al. DEVELOPMENTAL DYNAMICS
- Survival motor neuron gene 2 silencing by DNA methylation correlates with spinal muscular atrophy disease severity and can be bypassed by histone deacetylase inhibition
- (2008) Jan Hauke et al. HUMAN MOLECULAR GENETICS
- Inhibition of specific HDACs and sirtuins suppresses pathogenesis in a Drosophila model of Huntington’s disease
- (2008) Judit Pallos et al. HUMAN MOLECULAR GENETICS
- Valproic acid inhibits Aβ production, neuritic plaque formation, and behavioral deficits in Alzheimer's disease mouse models
- (2008) Hong Qing et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Nicotinamide Restores Cognition in Alzheimer's Disease Transgenic Mice via a Mechanism Involving Sirtuin Inhibition and Selective Reduction of Thr231-Phosphotau
- (2008) K. N. Green et al. JOURNAL OF NEUROSCIENCE
- Microtubule Acetylation Through HDAC6 Inhibition Results in Increased Transfection Efficiency
- (2008) Erin E Vaughan et al. MOLECULAR THERAPY
- Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds
- (2008) Danwei Huangfu et al. NATURE BIOTECHNOLOGY
- Therapeutic application of histone deacetylase inhibitors for central nervous system disorders
- (2008) Aleksey G. Kazantsev et al. NATURE REVIEWS DRUG DISCOVERY
- The many roles of histone deacetylases in development and physiology: implications for disease and therapy
- (2008) Michael Haberland et al. NATURE REVIEWS GENETICS
- The Rpd3/Hda1 family of lysine deacetylases: from bacteria and yeast to mice and men
- (2008) Xiang-Jiao Yang et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Deregulation of HDAC1 by p25/Cdk5 in Neurotoxicity
- (2008) Dohoon Kim et al. NEURON
- Valproic acid promotes neuronal differentiation by induction of proneural factors in association with H4 acetylation
- (2008) In Tag Yu et al. NEUROPHARMACOLOGY
- Histone deacetylase SIRT1 modulates neuronal differentiation by its nuclear translocation
- (2008) S. Hisahara et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The HDAC inhibitor 4b ameliorates the disease phenotype and transcriptional abnormalities in Huntington's disease transgenic mice
- (2008) E. A. Thomas et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- HDAC6: a key regulator of cytoskeleton, cell migration and cell–cell interactions
- (2008) Agustín Valenzuela-Fernández et al. TRENDS IN CELL BIOLOGY
- Characterization of the action of antipsychotic subtypes on valproate-induced chromatin remodeling
- (2008) Alessandro Guidotti et al. TRENDS IN PHARMACOLOGICAL SCIENCES
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