Reducing HDAC6 ameliorates cognitive deficits in a mouse model for Alzheimer's disease

Dysregulation of Histone Acetylation in the APP/PS1 Mouse Model of Alzheimer's Disease

(2017) Yitshak I. Francis et al.   JOURNAL OF ALZHEIMERS DISEASE

Alzheimer's Disease: The Quest to Understand Complexity

(2017) Sueli C.F. Marques et al.   JOURNAL OF ALZHEIMERS DISEASE

HDAC3 Is a Critical Negative Regulator of Long-Term Memory Formation

(2011) S. C. McQuown et al.   JOURNAL OF NEUROSCIENCE

HDAC6 inhibitors reverse axonal loss in a mouse model of mutant HSPB1–induced Charcot-Marie-Tooth disease

(2011) Constantin d'Ydewalle et al.   NATURE MEDICINE

Hdac6 Knock-Out Increases Tubulin Acetylation but Does Not Modify Disease Progression in the R6/2 Mouse Model of Huntington's Disease

(2011) Anna Bobrowska et al.   PLoS One

Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models

(2010) Lars M. Ittner et al.   CELL

Phenylbutyrate rescues dendritic spine loss associated with memory deficits in a mouse model of Alzheimer disease

(2010) Ana Ricobaraza et al.   HIPPOCAMPUS

Aβ promotes Alzheimer’s disease-like cytoskeleton abnormalities with consequences to APP processing in neurons

(2010) Ana Gabriela Henriques et al.   JOURNAL OF NEUROCHEMISTRY

The anaphase promoting complex is required for memory function in mice

(2010) T. Kuczera et al.   LEARNING & MEMORY

Amyloid-β-Derived Diffusible Ligands Cause Impaired Axonal Transport of Mitochondria in Neurons

(2010) Xinglong Wang et al.   Neurodegenerative Diseases

HDAC6 Regulates Mitochondrial Transport in Hippocampal Neurons

(2010) Sigeng Chen et al.   PLoS One

Relative Capability of MR Imaging and FDG PET to Depict Changes Associated with Prodromal and Early Alzheimer Disease

(2010) David S. Karow et al.   RADIOLOGY

Altered Histone Acetylation Is Associated with Age-Dependent Memory Impairment in Mice

(2010) S. Peleg et al.   SCIENCE

Targeting the correct HDAC(s) to treat cognitive disorders

(2010) André Fischer et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

The epigenetic bottleneck of neurodegenerative and psychiatric diseases

(2009) Farahnaz Sananbenesi et al.   BIOLOGICAL CHEMISTRY

Elongator Controls the Migration and Differentiation of Cortical Neurons through Acetylation of α-Tubulin

(2009) Catherine Creppe et al.   CELL

Impaired Balance of Mitochondrial Fission and Fusion in Alzheimer's Disease

(2009) X. Wang et al.   JOURNAL OF NEUROSCIENCE

HDAC2 negatively regulates memory formation and synaptic plasticity

(2009) Ji-Song Guan et al.   NATURE

Phenylbutyrate Ameliorates Cognitive Deficit and Reduces Tau Pathology in an Alzheimer's Disease Mouse Model

(2009) Ana Ricobaraza et al.   NEUROPSYCHOPHARMACOLOGY

Inhibitors of Class 1 Histone Deacetylases Reverse Contextual Memory Deficits in a Mouse Model of Alzheimer's Disease

(2009) Mark Kilgore et al.   NEUROPSYCHOPHARMACOLOGY

HDAC6 is a target for protection and regeneration following injury in the nervous system

(2009) M. A. Rivieccio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epigenetic targets of HDAC inhibition in neurodegenerative and psychiatric disorders

(2008) T ABEL et al.   CURRENT OPINION IN PHARMACOLOGY

Histone deacetylase 6 interacts with the microtubule-associated protein tau

(2008) Huiping Ding et al.   JOURNAL OF NEUROCHEMISTRY

Mice Lacking Histone Deacetylase 6 Have Hyperacetylated Tubulin but Are Viable and Develop Normally

(2008) Y. Zhang et al.   MOLECULAR AND CELLULAR BIOLOGY

GTPase dependent recruitment of Grif-1 by Miro1 regulates mitochondrial trafficking in hippocampal neurons

(2008) Andrew F. MacAskill et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

(2008) Ganesh M Shankar et al.   NATURE MEDICINE

Thirty years of Alzheimer's disease genetics: the implications of systematic meta-analyses

(2008) Lars Bertram et al.   NATURE REVIEWS NEUROSCIENCE

Tau-based treatment strategies in neurodegenerative diseases

(2008) Anja Schneider et al.   Neurotherapeutics

HDAC6: a key regulator of cytoskeleton, cell migration and cell–cell interactions

(2008) Agustín Valenzuela-Fernández et al.   TRENDS IN CELL BIOLOGY

SIRT2, tubulin deacetylation, and oligodendroglia differentiation

(2007) Bor Luen Tang et al.   CELL MOTILITY AND THE CYTOSKELETON