Genome editing with the CRISPR‐Cas system: an art, ethics and global regulatory perspective
出版年份 2020 全文链接
标题
Genome editing with the CRISPR‐Cas system: an art, ethics and global regulatory perspective
作者
关键词
-
出版物
PLANT BIOTECHNOLOGY JOURNAL
Volume -, Issue -, Pages -
出版商
Wiley
发表日期
2020-04-10
DOI
10.1111/pbi.13383
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- CRISPR/Cas Systems in Genome Editing: Methodologies and Tools for sgRNA Design, Off‐Target Evaluation, and Strategies to Mitigate Off‐Target Effects
- (2020) Hakim Manghwar et al. Advanced Science
- CRISPR–Cas9 a boon or bane: the bumpy road ahead to cancer therapeutics
- (2019) Debarati Ghosh et al. Cancer Cell International
- Experiments that led to the first gene-edited babies: the ethical failings and the urgent need for better governance
- (2019) Jing-ru LI et al. Journal of Zhejiang University-SCIENCE B
- Gene-Edited Crops: Towards a Harmonized Safety Assessment
- (2019) Gijs A. Kleter et al. TRENDS IN BIOTECHNOLOGY
- The Challenges of Medical Ethics in China: Are Gene-Edited Babies Enough?
- (2019) Zeng Jie Ye et al. SCIENCE AND ENGINEERING ETHICS
- Did a permissive scientific culture encourage the ‘CRISPR babies’ experiment?
- (2019) Donna Dickenson et al. NATURE BIOTECHNOLOGY
- Genome-wide target specificity of CRISPR RNA-guided adenine base editors
- (2019) Daesik Kim et al. NATURE BIOTECHNOLOGY
- Adopt a moratorium on heritable genome editing
- (2019) Eric S. Lander et al. NATURE
- Advances in CRISPR-Cas systems for RNA targeting, tracking and editing
- (2019) Fei Wang et al. BIOTECHNOLOGY ADVANCES
- The application of the CRISPR-Cas9 genome editing machinery in food and agricultural science: Current status, future perspectives, and associated challenges
- (2019) Ismail Eş et al. BIOTECHNOLOGY ADVANCES
- Ethics of Human Genome Editing
- (2019) Barry S. Coller Annual Review of Medicine
- Australian gene-editing rules adopt ‘middle ground’
- (2019) Smriti Mallapaty NATURE
- Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors
- (2019) Julian Grünewald et al. NATURE
- Robust CRISPR /Cpf1(Cas12a) mediated genome editing in allotetraploid cotton ( G. hirsutum )
- (2019) Bo Li et al. PLANT BIOTECHNOLOGY JOURNAL
- A New Rice Breeding Method: CRISPR /Cas9 System Editing of the Xa13 Promoter to Cultivate Transgene‐free Bacterial Blight‐resistant Rice
- (2019) Changyan Li et al. PLANT BIOTECHNOLOGY JOURNAL
- European Court of Justice delivers no justice to Europe on genome‐edited crops
- (2019) Alan H. Schulman et al. PLANT BIOTECHNOLOGY JOURNAL
- Simplified adenine base editors improve adenine base editing efficiency in rice
- (2019) Kai Hua et al. PLANT BIOTECHNOLOGY JOURNAL
- Transient cotransformation of CRISPR /Cas9 and oligonucleotide templates enables efficient editing of target loci in Physcomitrella patens
- (2019) Peishan Yi et al. PLANT BIOTECHNOLOGY JOURNAL
- Generation of a multiplex mutagenesis population via pooled CRISPR ‐Cas9 in soya bean
- (2019) Mengyan Bai et al. PLANT BIOTECHNOLOGY JOURNAL
- Knockout of two Bna MAX 1 homologs by CRISPR /Cas9‐targeted mutagenesis improves plant architecture and increases yield in rapeseed ( Brassica napus L.)
- (2019) Ming Zheng et al. PLANT BIOTECHNOLOGY JOURNAL
- Genome-editing technologies: the gap between application and policy
- (2019) Gousi Li et al. Science China-Life Sciences
- CRISPR/Cas System: Recent Advances and Future Prospects for Genome Editing
- (2019) Hakim Manghwar et al. TRENDS IN PLANT SCIENCE
- CRISPR base editors: genome editing without double-stranded breaks
- (2018) Ayman Eid et al. BIOCHEMICAL JOURNAL
- Legal Regulation of Plant Genome Editing with the CRISPR/Cas9 Technology as an Example
- (2018) M. O. Medvedieva et al. Cytology and Genetics
- Risk analysis for genome editing-derived food safety in China
- (2018) Wei Gao et al. FOOD CONTROL
- History of CRISPR-Cas from Encounter with a Mysterious Repeated Sequence to Genome Editing Technology
- (2018) Yoshizumi Ishino et al. JOURNAL OF BACTERIOLOGY
- CRISPR Ethics: Moral Considerations for Applications of a Powerful Tool
- (2018) Carolyn Brokowski et al. JOURNAL OF MOLECULAR BIOLOGY
- Editing the human genome: balancing safety and regulation
- (2018) The Lancet LANCET
- Improved Base Editor for Efficiently Inducing Genetic Variations in Rice with CRISPR/Cas9-Guided Hyperactive hAID Mutant
- (2018) Bin Ren et al. Molecular Plant
- With a free pass, CRISPR-edited plants reach market in record time
- (2018) Emily Waltz NATURE BIOTECHNOLOGY
- CRISPR off-target analysis in genetically engineered rats and mice
- (2018) Keith R. Anderson et al. NATURE METHODS
- The Swedish policy approach to directed mutagenesis in a European context
- (2018) Dennis Eriksson PHYSIOLOGIA PLANTARUM
- High-efficiency genome editing using a dmc1 promoter-controlled CRISPR/Cas9 system in maize
- (2018) Chao Feng et al. PLANT BIOTECHNOLOGY JOURNAL
- Activities and specificities of CRISPR-Cas9 and Cas12a nucleases for targeted mutagenesis in maize
- (2018) Keunsub Lee et al. PLANT BIOTECHNOLOGY JOURNAL
- Potential high-frequency off-target mutagenesis induced by CRISPR/Cas9 in Arabidopsis and its prevention
- (2018) Qiang Zhang et al. PLANT MOLECULAR BIOLOGY
- The CRISPR tool kit for genome editing and beyond
- (2018) Mazhar Adli Nature Communications
- Agricultural GMOs—What We Know and Where Scientists Disagree
- (2018) David Zilberman et al. Sustainability
- High Efficiency Gene Correction in Hematopoietic Cells by Donor-Template-Free CRISPR/Cas9 Genome Editing
- (2018) Duran Sürün et al. Molecular Therapy-Nucleic Acids
- CRISPR-Cas systems: ushering in the new genome editing era
- (2018) Fernando Perez Rojo et al. Bioengineered
- CRISPR/Cascade 9-Mediated Genome Editing-Challenges and Opportunities
- (2018) Bhaskar Roy et al. Frontiers in Genetics
- Gene editing in human development: ethical concerns and practical applications
- (2018) Janet Rossant DEVELOPMENT
- Erratum: Repair of double-strand breaks induced by CRISPR–Cas9 leads to large deletions and complex rearrangements
- (2018) Michael Kosicki et al. NATURE BIOTECHNOLOGY
- CRISPR-Cas9 ribonucleoprotein-mediated co-editing and counterselection in the rice blast fungus
- (2018) Andrew J. Foster et al. Scientific Reports
- A New Zealand Perspective on the Application and Regulation of Gene Editing
- (2018) Steffi Fritsche et al. Frontiers in Plant Science
- Gene-edited babies: Chinese Academy of Medical Sciences’ response and action
- (2018) Chen Wang et al. LANCET
- A comparison of the EU regulatory approach to directed mutagenesis with that of other jurisdictions, consequences for international trade and potential steps forward
- (2018) Dennis Eriksson et al. NEW PHYTOLOGIST
- Whole genome sequencing reveals rare off-target mutations and considerable inherent genetic or/and somaclonal variations in CRISPR/Cas9-edited cotton plants
- (2018) Jianying Li et al. PLANT BIOTECHNOLOGY JOURNAL
- Enhanced genome editing in rice using single transcript unit CRISPR-Lb Cpf1 systems
- (2018) Rongfang Xu et al. PLANT BIOTECHNOLOGY JOURNAL
- CRISPR/Cas9 can mediate high-efficiency off-target mutations in mice in vivo
- (2018) Neeraj K Aryal et al. Cell Death & Disease
- Development of Wheat With Hypoimmunogenic Gluten Obstructed by the Gene Editing Policy in Europe
- (2018) Aurélie Jouanin et al. Frontiers in Plant Science
- Programmable Molecular Scissors: Applications of a New Tool for Genome Editing in Biotech
- (2018) Subbroto Kumar Saha et al. Molecular Therapy-Nucleic Acids
- Bioethics Panels Open Door Slightly to Germline Gene Editing
- (2017) Jeff Lyon JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- A technological and regulatory outlook on CRISPR crop editing
- (2017) Rea Globus et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- The Application of CRISPR/Cas Technology to Efficiently Model Complex Cancer Genomes in Stem Cells
- (2017) Adam Albitar et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Methods and Applications of CRISPR-Mediated Base Editing in Eukaryotic Genomes
- (2017) Gaelen T. Hess et al. MOLECULAR CELL
- Gene editing in legal limbo in Europe
- (2017) NATURE
- Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage
- (2017) Nicole M. Gaudelli et al. NATURE
- Precise base editing in rice, wheat and maize with a Cas9-cytidine deaminase fusion
- (2017) Yuan Zong et al. NATURE BIOTECHNOLOGY
- Targeted base editing in rice and tomato using a CRISPR-Cas9 cytidine deaminase fusion
- (2017) Zenpei Shimatani et al. NATURE BIOTECHNOLOGY
- Designing Ethical Trials of Germline Gene Editing
- (2017) Bryan Cwik NEW ENGLAND JOURNAL OF MEDICINE
- Multiplexed CRISPR/Cas9-mediated metabolic engineering of γ-aminobutyric acid levels in Solanum lycopersicum
- (2017) Rui Li et al. PLANT BIOTECHNOLOGY JOURNAL
- Fostering responsible research with genome editing technologies: a European perspective
- (2017) Hervé Chneiweiss et al. TRANSGENIC RESEARCH
- CRISPR-Cpf1: A New Tool for Plant Genome Editing
- (2017) Syed Shan-e-Ali Zaidi et al. TRENDS IN PLANT SCIENCE
- Efficient DNA-free genome editing of bread wheat using CRISPR/Cas9 ribonucleoprotein complexes
- (2017) Zhen Liang et al. Nature Communications
- How should the applications of genome editing be assessed and regulated?
- (2017) Robin Fears et al. eLife
- Generation of High-Amylose Rice through CRISPR/Cas9-Mediated Targeted Mutagenesis of Starch Branching Enzymes
- (2017) Yongwei Sun et al. Frontiers in Plant Science
- New GMO regulations for old: Determining a new future for EU crop biotechnology
- (2017) John Davison et al. GM Crops & Food-Biotechnology in Agriculture and the Food Chain
- A high-efficiency CRISPR/Cas9 system for targeted mutagenesis in Cotton (Gossypium hirsutum L.)
- (2017) Chao Li et al. Scientific Reports
- Genomic variation and DNA repair associated with soybean transgenesis: a comparison to cultivars and mutagenized plants
- (2016) Justin E. Anderson et al. BMC BIOTECHNOLOGY
- CRISPR/Cas9 Platforms for Genome Editing in Plants: Developments and Applications
- (2016) Xingliang Ma et al. Molecular Plant
- UK scientists gain licence to edit genes in human embryos
- (2016) Ewen Callaway NATURE
- CRISPR gene-editing tested in a person for the first time
- (2016) David Cyranoski NATURE
- Embryology policy: Revisit the 14-day rule
- (2016) Insoo Hyun et al. NATURE
- How the US CRISPR patent probe will play out
- (2016) Heidi Ledford NATURE
- Gene-edited CRISPR mushroom escapes US regulation
- (2016) Emily Waltz NATURE
- Genome-wide specificities of CRISPR-Cas Cpf1 nucleases in human cells
- (2016) Benjamin P Kleinstiver et al. NATURE BIOTECHNOLOGY
- A proposed regulatory framework for genome-edited crops
- (2016) Sanwen Huang et al. NATURE GENETICS
- Directed evolution using dCas9-targeted somatic hypermutation in mammalian cells
- (2016) Gaelen T Hess et al. NATURE METHODS
- Structural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B
- (2016) Ke Shi et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- CRISPR-Cas: biology, mechanisms and relevance
- (2016) Frank Hille et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Efficient targeted multiallelic mutagenesis in tetraploid potato (Solanum tuberosum) by transient CRISPR-Cas9 expression in protoplasts
- (2016) Mariette Andersson et al. PLANT CELL REPORTS
- Regulatory hurdles for genome editing: process- vs. product-based approaches in different regulatory contexts
- (2016) Thorben Sprink et al. PLANT CELL REPORTS
- Structural basis for targeted DNA cytosine deamination and mutagenesis by APOBEC3A and APOBEC3B
- (2016) Ke Shi et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- DNA-Free Genetically Edited Grapevine and Apple Protoplast Using CRISPR/Cas9 Ribonucleoproteins
- (2016) Mickael Malnoy et al. Frontiers in Plant Science
- A future scenario of the global regulatory landscape regarding genome-edited crops
- (2016) Tetsuya Ishii et al. GM Crops & Food-Biotechnology in Agriculture and the Food Chain
- Canadian regulatory perspectives on genome engineered crops
- (2016) Stuart J. Smyth GM Crops & Food-Biotechnology in Agriculture and the Food Chain
- The History of Patenting Genetic Material
- (2015) Jacob S. Sherkow et al. Annual Review of Genetics
- Germ line genome editing in clinics: the approaches, objectives and global society
- (2015) Tetsuya Ishii Briefings in Functional Genomics
- Co-transcriptional DNA and RNA Cleavage during Type III CRISPR-Cas Immunity
- (2015) Poulami Samai et al. CELL
- Genome-wide CRISPR Screen in a Mouse Model of Tumor Growth and Metastasis
- (2015) Sidi Chen et al. CELL
- Genome editing in plants via designed zinc finger nucleases
- (2015) Joseph F. Petolino IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-PLANT
- CRISPR, the disruptor
- (2015) Heidi Ledford NATURE
- Don’t edit the human germ line
- (2015) Edward Lanphier et al. NATURE
- Unbiased detection of off-target cleavage by CRISPR-Cas9 and TALENs using integrase-defective lentiviral vectors
- (2015) Xiaoling Wang et al. NATURE BIOTECHNOLOGY
- Therapeutic genome editing: prospects and challenges
- (2015) David Benjamin Turitz Cox et al. NATURE MEDICINE
- Digenome-seq: genome-wide profiling of CRISPR-Cas9 off-target effects in human cells
- (2015) Daesik Kim et al. NATURE METHODS
- Oligonucleotide-directed mutagenesis for precision gene editing
- (2015) Noel J. Sauer et al. PLANT BIOTECHNOLOGY JOURNAL
- The Regulatory Status of Genome-edited Crops
- (2015) Jeffrey D. Wolt et al. PLANT BIOTECHNOLOGY JOURNAL
- A prudent path forward for genomic engineering and germline gene modification
- (2015) D. Baltimore et al. SCIENCE
- Are we ready for back-to-nature crop breeding?
- (2015) Michael G. Palmgren et al. TRENDS IN PLANT SCIENCE
- Towards social acceptance of plant breeding by genome editing
- (2015) Motoko Araki et al. TRENDS IN PLANT SCIENCE
- CRISPR/Cas9-mediated gene editing in human tripronuclear zygotes
- (2015) Puping Liang et al. Protein & Cell
- Off-target Effects in CRISPR/Cas9-mediated Genome Engineering
- (2015) Xiao-Hui Zhang et al. Molecular Therapy-Nucleic Acids
- Precise Correction of the Dystrophin Gene in Duchenne Muscular Dystrophy Patient Induced Pluripotent Stem Cells by TALEN and CRISPR-Cas9
- (2015) Hongmei Lisa Li et al. Stem Cell Reports
- Sustainability Council of New Zealand Trust v. The Environmental Protection Authority: Gene editing technologies and the law
- (2015) Drew L Kershen GM Crops & Food-Biotechnology in Agriculture and the Food Chain
- Regulatory framework for gene editing and other new breeding techniques (NBTs) in Argentina
- (2015) Agustina I Whelan et al. GM Crops & Food-Biotechnology in Agriculture and the Food Chain
- Genome Engineering with Targetable Nucleases
- (2014) Dana Carroll Annual Review of Biochemistry
- Seamless gene correction of β-thalassemia mutations in patient-specific iPSCs using CRISPR/Cas9 andpiggyBac
- (2014) Fei Xie et al. GENOME RESEARCH
- Genetically engineered crops that fly under the US regulatory radar
- (2014) Alex Camacho et al. NATURE BIOTECHNOLOGY
- Simultaneous editing of three homoeoalleles in hexaploid bread wheat confers heritable resistance to powdery mildew
- (2014) Yanpeng Wang et al. NATURE BIOTECHNOLOGY
- Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype
- (2014) Hao Yin et al. NATURE BIOTECHNOLOGY
- Social, ethical and legal considerations raised by the discovery and patenting of the BRCA1 and BRCA2 genes
- (2014) Yann Joly et al. NEW GENETICS AND SOCIETY
- Efficient Gene Editing in Tomato in the First Generation Using the Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR-Associated9 System
- (2014) C. Brooks et al. PLANT PHYSIOLOGY
- Targeted Genome Editing of Sweet Orange Using Cas9/sgRNA
- (2014) Hongge Jia et al. PLoS One
- Prevention of muscular dystrophy in mice by CRISPR/Cas9-mediated editing of germline DNA
- (2014) C. Long et al. SCIENCE
- The new frontier of genome engineering with CRISPR-Cas9
- (2014) J. A. Doudna et al. SCIENCE
- Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity
- (2013) F. Ann Ran et al. CELL
- Efficient genome editing in plants using a CRISPR/Cas system
- (2013) Zhengyan Feng et al. CELL RESEARCH
- Targeted mutagenesis in rice using CRISPR-Cas system
- (2013) Jin Miao et al. CELL RESEARCH
- Functional Repair of CFTR by CRISPR/Cas9 in Intestinal Stem Cell Organoids of Cystic Fibrosis Patients
- (2013) Gerald Schwank et al. Cell Stem Cell
- Targeted Mutagenesis in Zea mays Using TALENs and the CRISPR/Cas System
- (2013) Zhen Liang et al. Journal of Genetics and Genomics
- Genome-wide recessive genetic screening in mammalian cells with a lentiviral CRISPR-guide RNA library
- (2013) Hiroko Koike-Yusa et al. NATURE BIOTECHNOLOGY
- High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells
- (2013) Yanfang Fu et al. NATURE BIOTECHNOLOGY
- Multiplex Genome Engineering Using CRISPR/Cas Systems
- (2013) L. Cong et al. SCIENCE
- Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria
- (2012) G. Gasiunas et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Discovery of Zinc Fingers and Their Applications in Gene Regulation and Genome Manipulation
- (2010) Aaron Klug Annual Review of Biochemistry
- TAL nucleases (TALNs): hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain
- (2010) Ting Li et al. NUCLEIC ACIDS RESEARCH
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