The Roles of Cyclin-Dependent Kinases in Cell-Cycle Progression and Therapeutic Strategies in Human Breast Cancer
出版年份 2020 全文链接
标题
The Roles of Cyclin-Dependent Kinases in Cell-Cycle Progression and Therapeutic Strategies in Human Breast Cancer
作者
关键词
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出版物
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 21, Issue 6, Pages 1960
出版商
MDPI AG
发表日期
2020-03-13
DOI
10.3390/ijms21061960
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Anticancer effect of nor-wogonin (5, 7, 8-trihydroxyflavone) on human triple-negative breast cancer cells via downregulation of TAK1, NF-κB, and STAT3
- (2019) Amer Ali Abd El-Hafeez et al. Pharmacological Reports
- Fomes fomentarius Ethanol Extract Exerts Inhibition of Cell Growth and Motility Induction of Apoptosis via Targeting AKT in Human Breast Cancer MDA-MB-231 Cells
- (2019) Seon-OK Lee et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Combined inhibition of STAT3 and DNA repair in palbociclib-resistant ER-positive breast cancer
- (2019) Nicole M. Kettner et al. CLINICAL CANCER RESEARCH
- Role of Cyclin-Dependent Kinase Inhibitors in Endometrial Cancer
- (2019) Gaia Giannone et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Updates on the CDK4/6 Inhibitory Strategy and Combinations in Breast Cancer
- (2019) Sobhani et al. Cells
- MiR-128-3p suppresses breast cancer cellular progression via targeting LIMK1
- (2019) Junyong Zhao et al. BIOMEDICINE & PHARMACOTHERAPY
- Overexpression of TK1 and CDK9 in plasma-derived exosomes is associated with clinical resistance to CDK4/6 inhibitors in metastatic breast cancer patients
- (2019) Marzia Del Re et al. BREAST CANCER RESEARCH AND TREATMENT
- Long noncoding RNA CASC2 promotes paclitaxel resistance in breast cancer through regulation of miR-18a-5p/CDK19
- (2019) Pengfei Zheng et al. HISTOCHEMISTRY AND CELL BIOLOGY
- Resveratrol chemosensitizes adriamycin‐resistant breast cancer cells by modulating miR‐122‐5p
- (2019) Wei Zhang et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Upregulation of hsa_circ_0136666 contributes to breast cancer progression by sponging miR‐1299 and targeting CDK6
- (2019) Li‐Hong Liu et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- The microRNA‐141‐3p/ CDK8 pathway regulates the chemosensitivity of breast cancer cells to trastuzumab
- (2019) Wenqing Song et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- LINC00511 knockdown enhances paclitaxel cytotoxicity in breast cancer via regulating miR-29c/CDK6 axis
- (2019) Hualong Zhang et al. LIFE SCIENCES
- Overall Survival with Ribociclib plus Endocrine Therapy in Breast Cancer
- (2019) Seock-Ah Im et al. NEW ENGLAND JOURNAL OF MEDICINE
- Icariin induces apoptosis by suppressing autophagy in tamoxifen-resistant breast cancer cell line MCF-7/TAM
- (2019) Xia Cheng et al. Breast Cancer
- Cyclin dependent kinase (CDK) inhibitors as anticancer drugs: Recent advances (2015–2019)
- (2019) Concepción Sánchez-Martínez et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Therapeutic Targeting of CDK12/CDK13 in Triple-Negative Breast Cancer
- (2019) Victor Quereda et al. CANCER CELL
- Potent Cell-Cycle Inhibition and Upregulation of Immune Response with Abemaciclib and Anastrozole in neoMONARCH, Phase II Neoadjuvant Study in HR+/HER2− Breast Cancer
- (2019) Sara A. Hurvitz et al. CLINICAL CANCER RESEARCH
- A clinical evaluation of treatments that target cell cycle machinery in breast cancer
- (2019) Palma Fedele et al. EXPERT OPINION ON PHARMACOTHERAPY
- Antitumor Activity of Vanicoside B Isolated from Persicaria dissitiflora by Targeting CDK8 in Triple-Negative Breast Cancer Cells
- (2019) Donghwa Kim et al. JOURNAL OF NATURAL PRODUCTS
- CDK2-mediated site-specific phosphorylation of EZH2 drives and maintains triple-negative breast cancer
- (2019) Lei Nie et al. Nature Communications
- An increased cell cycle gene network determines MEK and Akt inhibitor double resistance in triple-negative breast cancer
- (2019) Vera E. van der Noord et al. Scientific Reports
- Concurrent targeting of BMI1 and CDK4/6 abrogates tumor growth in vitro and in vivo
- (2019) Ramesh Elango et al. Scientific Reports
- Pre-treatment with the CDK4/6 inhibitor palbociclib improves the efficacy of paclitaxel in TNBC cells
- (2019) Daniele Cretella et al. Scientific Reports
- MicroRNAs Involved in Carcinogenesis, Prognosis, Therapeutic Resistance, and Applications in Human Triple-Negative Breast Cancer
- (2019) Lei Ding et al. Cells
- PA28α/β Promote Breast Cancer Cell Invasion and Metastasis via Down-Regulation of CDK15
- (2019) Shengnan Li et al. Frontiers in Oncology
- Overall Survival with Ribociclib plus Fulvestrant in Advanced Breast Cancer
- (2019) Dennis J. Slamon et al. NEW ENGLAND JOURNAL OF MEDICINE
- Panduratin A Inhibits Cell Proliferation by Inducing G0/G1 Phase Cell Cycle Arrest and Induces Apoptosis in Breast Cancer Cells
- (2018) Qiuming Liu et al. Biomolecules & Therapeutics
- Downregulation of dual-specificity tyrosine-regulated kinase 2 promotes tumor cell proliferation and invasion by enhancing cyclin-dependent kinase 14 expression in breast cancer
- (2018) Yoshimi Imawari et al. CANCER SCIENCE
- Cycling Toward Progress: Ribociclib, a CDK 4/6 Inhibitor for Breast Cancer
- (2018) Laura Spring et al. CLINICAL CANCER RESEARCH
- The Emerging Picture of CDK11: Genetic, Functional and Medicinal Aspects
- (2018) Nikolas Ferreira dos Santos Paparidis et al. CURRENT MEDICINAL CHEMISTRY
- C-glycosyl flavone from Urginea indica inhibits proliferation & angiogenesis & induces apoptosis via cyclin-dependent kinase 6 in human breast, hepatic & colon cancer cell lines
- (2018) RamaRao Malla et al. INDIAN JOURNAL OF MEDICAL RESEARCH
- Phase III Randomized Study of Ribociclib and Fulvestrant in Hormone Receptor–Positive, Human Epidermal Growth Factor Receptor 2–Negative Advanced Breast Cancer: MONALEESA-3
- (2018) Dennis J. Slamon et al. JOURNAL OF CLINICAL ONCOLOGY
- Ribociclib plus endocrine therapy for premenopausal women with hormone-receptor-positive, advanced breast cancer (MONALEESA-7): a randomised phase 3 trial
- (2018) Debu Tripathy et al. LANCET ONCOLOGY
- Combined Inhibition of mTOR and CDK4/6 Is Required for Optimal Blockade of E2F Function and Long-term Growth Inhibition in Estrogen Receptor–positive Breast Cancer
- (2018) Chrysiis Michaloglou et al. MOLECULAR CANCER THERAPEUTICS
- Loss of Cdk5 in breast cancer cells promotes ROS-mediated cell death through dysregulation of the mitochondrial permeability transition pore
- (2018) Saranya NavaneethaKrishnan et al. ONCOGENE
- Galangin Induces Apoptosis in MCF-7 Human Breast Cancer Cells Through Mitochondrial Pathway and Phosphatidylinositol 3-Kinase/Akt Inhibition
- (2018) Dan Liu et al. PHARMACOLOGY
- The relationship of CDK18 expression in breast cancer to clinicopathological parameters and therapeutic response
- (2018) Giancarlo Barone et al. Oncotarget
- Combined Inhibition of ATR and WEE1 as a Novel Therapeutic Strategy in Triple-Negative Breast Cancer
- (2018) Juan Jin et al. NEOPLASIA
- Targeting the cell cycle in breast cancer: towards the next phase
- (2018) KL Thu et al. CELL CYCLE
- The Dual Role of MicroRNAs in Colorectal Cancer Progression
- (2018) Lei Ding et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Current Landscape of Targeted Therapies for Hormone-Receptor Positive, HER2 Negative Metastatic Breast Cancer
- (2018) Tarah J. Ballinger et al. Frontiers in Oncology
- Activated kinase screening identifies the IKBKE oncogene as a positive regulator of autophagy
- (2018) Margherita Leonardi et al. Autophagy
- Rhomboid domain-containing protein 1 promotes breast cancer progression by regulating the p-Akt and CDK2 levels
- (2018) Xin Zhang et al. Cell Communication and Signaling
- Overall Survival with Palbociclib and Fulvestrant in Advanced Breast Cancer
- (2018) Nicholas C. Turner et al. NEW ENGLAND JOURNAL OF MEDICINE
- Keeping CDK18 in balance to prevent DNA replication stress in breast cancer
- (2018) Esmée Braams et al. Oncotarget
- miR-455 inhibits breast cancer cell proliferation through targeting CDK14
- (2017) Bing Wang et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Effect of bis(hydroxymethyl) alkanoate curcuminoid derivative MTH-3 on cell cycle arrest, apoptotic and autophagic pathway in triple-negative breast adenocarcinoma MDA-MB-231 cells: An in vitro study
- (2017) Ling-Chu Chang et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- MONARCH 2: Abemaciclib in Combination With Fulvestrant in Women With HR+/HER2− Advanced Breast Cancer Who Had Progressed While Receiving Endocrine Therapy
- (2017) George W. Sledge et al. JOURNAL OF CLINICAL ONCOLOGY
- Evaluation of CDK12 Protein Expression as a Potential Novel Biomarker for DNA Damage Response–Targeted Therapies in Breast Cancer
- (2017) Kalnisha Naidoo et al. MOLECULAR CANCER THERAPEUTICS
- CDK12 regulates alternative last exon mRNA splicing and promotes breast cancer cell invasion
- (2017) Jerry F. Tien et al. NUCLEIC ACIDS RESEARCH
- Clinical Management of Potential Toxicities and Drug Interactions Related to Cyclin‐Dependent Kinase 4/6 Inhibitors in Breast Cancer: Practical Considerations and Recommendations
- (2017) Laura M. Spring et al. ONCOLOGIST
- Inhibitors of cyclin-dependent kinases as cancer therapeutics
- (2017) Steven R. Whittaker et al. PHARMACOLOGY & THERAPEUTICS
- CDK8: a new breast cancer target
- (2017) John Crown Oncotarget
- The awakening of the CDK10/Cyclin M protein kinase
- (2017) Vincent J. Guen et al. Oncotarget
- Mechanisms of the anti-tumor activity of Methyl 2-(-5-fluoro-2-hydroxyphenyl)-1 H-benzo[d]imidazole-5-carboxylate against breast cancer in vitro and in vivo
- (2017) Mohadeseh Hasanpourghadi et al. Oncotarget
- Ribociclib plus letrozole in early breast cancer: A presurgical, window-of-opportunity study
- (2016) G. Curigliano et al. BREAST
- Clinical Development of the CDK4/6 Inhibitors Ribociclib and Abemaciclib in Breast Cancer
- (2016) Romualdo Barroso-Sousa et al. Breast Care
- A Phase I Study of the Cyclin-Dependent Kinase 4/6 Inhibitor Ribociclib (LEE011) in Patients with Advanced Solid Tumors and Lymphomas
- (2016) J. R. Infante et al. CLINICAL CANCER RESEARCH
- Cyclin-Dependent Kinase 14 Promotes Cell Proliferation, Migration and Invasion in Ovarian Cancer by Inhibiting Wnt Signaling Pathway
- (2016) Jun Ou-Yang et al. GYNECOLOGIC AND OBSTETRIC INVESTIGATION
- The RNA Polymerase II CTD: The Increasing Complexity of a Low-Complexity Protein Domain
- (2016) Célia Jeronimo et al. JOURNAL OF MOLECULAR BIOLOGY
- Fulvestrant plus palbociclib versus fulvestrant plus placebo for treatment of hormone-receptor-positive, HER2-negative metastatic breast cancer that progressed on previous endocrine therapy (PALOMA-3): final analysis of the multicentre, double-blind, phase 3 randomised controlled trial
- (2016) Massimo Cristofanilli et al. LANCET ONCOLOGY
- Sequential Combination Therapy of CDK Inhibition and Doxorubicin Is Synthetically Lethal in p53-Mutant Triple-Negative Breast Cancer
- (2016) N. A. Jabbour-Leung et al. MOLECULAR CANCER THERAPEUTICS
- Spectrum and Degree of CDK Drug Interactions Predicts Clinical Performance
- (2016) P. Chen et al. MOLECULAR CANCER THERAPEUTICS
- Triple-negative breast cancer: challenges and opportunities of a heterogeneous disease
- (2016) Giampaolo Bianchini et al. Nature Reviews Clinical Oncology
- Ribociclib as First-Line Therapy for HR-Positive, Advanced Breast Cancer
- (2016) Gabriel N. Hortobagyi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Human CDK18 promotes replication stress signaling and genome stability
- (2016) Giancarlo Barone et al. NUCLEIC ACIDS RESEARCH
- Cyclin-Dependent Kinase Inhibitors for the Treatment of Breast Cancer: Past, Present, and Future
- (2016) Adam J. DiPippo et al. PHARMACOTHERAPY
- Cdk5 disruption attenuates tumor PD-L1 expression and promotes antitumor immunity
- (2016) R. D. Dorand et al. SCIENCE
- Insights into APC/C: from cellular function to diseases and therapeutics
- (2016) Zhuan Zhou et al. Cell Division
- Potential role of PCTAIRE-2, PCTAIRE-3 and P-Histone H4 in amyloid precursor protein-dependent Alzheimer pathology
- (2016) Dale Chaput et al. Oncotarget
- The emerging roles and therapeutic potential of cyclin-dependent kinase 11 (CDK11) in human cancer
- (2016) Yubing Zhou et al. Oncotarget
- CDK4/6 inhibitors in breast cancer
- (2015) Tim Dukelow et al. ANTI-CANCER DRUGS
- Critical role of CDK11p58 in human breast cancer growth and angiogenesis
- (2015) Yayun Chi et al. BMC CANCER
- CDK7-Dependent Transcriptional Addiction in Triple-Negative Breast Cancer
- (2015) Yubao Wang et al. CELL
- PCTAIRE1/PCTK1/CDK16: a new oncotarget?
- (2015) Teruki Yanagi et al. CELL CYCLE
- FDA Approval: Palbociclib for the Treatment of Postmenopausal Patients with Estrogen Receptor-Positive, HER2-Negative Metastatic Breast Cancer
- (2015) J. A. Beaver et al. CLINICAL CANCER RESEARCH
- The Molecular Biology of Spindle Assembly Checkpoint Signaling Dynamics
- (2015) Andrea Musacchio CURRENT BIOLOGY
- Expression of CDK8 and CDK8-interacting Genes as Potential Biomarkers in Breast Cancer
- (2015) Eugenia Broude et al. CURRENT CANCER DRUG TARGETS
- miRNAs and Other Epigenetic Changes as Biomarkers in Triple Negative Breast Cancer
- (2015) Andrea Mathe et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Final results of EFC6663: A multicenter, international, phase 2 study of alvocidib for patients with fludarabine-refractory chronic lymphocytic leukemia
- (2015) Mark C. Lanasa et al. LEUKEMIA RESEARCH
- Characterization of Human Cyclin-Dependent Kinase 12 (CDK12) and CDK13 Complexes in C-Terminal Domain Phosphorylation, Gene Transcription, and RNA Processing
- (2015) Kaiwei Liang et al. MOLECULAR AND CELLULAR BIOLOGY
- The history and future of targeting cyclin-dependent kinases in cancer therapy
- (2015) Uzma Asghar et al. NATURE REVIEWS DRUG DISCOVERY
- Spatiotemporal regulation of the anaphase-promoting complex in mitosis
- (2015) Sushama Sivakumar et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The Mediator complex: a central integrator of transcription
- (2015) Benjamin L. Allen et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Palbociclib in Hormone-Receptor–Positive Advanced Breast Cancer
- (2015) Nicholas C. Turner et al. NEW ENGLAND JOURNAL OF MEDICINE
- Targeting Cyclin-Dependent Kinases and Cell Cycle Progression in Human Cancers
- (2015) Loredana Santo et al. SEMINARS IN ONCOLOGY
- Decreased CDK10 expression correlates with lymph node metastasis and predicts poor outcome in breast cancer patients - a short report
- (2015) Yanjie You et al. CELLULAR ONCOLOGY
- Cyclin-dependent kinase 11p110 (CDK11p110) is crucial for human breast cancer cell proliferation and growth
- (2015) Yubing Zhou et al. Scientific Reports
- PCTAIRE1-Knockdown Sensitizes Cancer Cells to TNF Family Cytokines
- (2015) Teruki Yanagi et al. PLoS One
- Phylogenetic analysis of CDK and cyclin proteins in premetazoan lineages
- (2014) Lihuan Cao et al. BMC EVOLUTIONARY BIOLOGY
- The Mediator complex: a master coordinator of transcription and cell lineage development
- (2014) J.-w. Yin et al. DEVELOPMENT
- Preclinical characterization of the CDK4/6 inhibitor LY2835219: in-vivo cell cycle-dependent/independent anti-tumor activities alone/in combination with gemcitabine
- (2014) Lawrence M. Gelbert et al. INVESTIGATIONAL NEW DRUGS
- Integrated Analysis of Whole Genome and Transcriptome Sequencing Reveals Diverse Transcriptomic Aberrations Driven by Somatic Genomic Changes in Liver Cancers
- (2014) Yuichi Shiraishi et al. PLoS One
- Cyclin-dependent kinases
- (2014) Marcos Malumbres GENOME BIOLOGY
- The two faces of Cdk8, a positive/negative regulator of transcription
- (2013) Josipa Nemet et al. BIOCHIMIE
- The Role of Cdk5 in Neuroendocrine Thyroid Cancer
- (2013) Karine Pozo et al. CANCER CELL
- HIF1A Employs CDK8-Mediator to Stimulate RNAPII Elongation in Response to Hypoxia
- (2013) Matthew D. Galbraith et al. CELL
- The Writers, Readers, and Functions of the RNA Polymerase II C-Terminal Domain Code
- (2013) Célia Jeronimo et al. CHEMICAL REVIEWS
- Randomized Phase II Trial of the Cyclin-Dependent Kinase Inhibitor Dinaciclib (MK-7965) Versus Capecitabine in Patients With Advanced Breast Cancer
- (2013) Monica M. Mita et al. Clinical Breast Cancer
- Cdks, cyclins and CKIs: roles beyond cell cycle regulation
- (2013) S. Lim et al. DEVELOPMENT
- The C-Terminal Domain of Rpb1 Functions on Other RNA Polymerase II Subunits
- (2013) Hyunsuk Suh et al. MOLECULAR CELL
- RB1 Status in Triple Negative Breast Cancer Cells Dictates Response to Radiation Treatment and Selective Therapeutic Drugs
- (2013) Tyler J. W. Robinson et al. PLoS One
- CDK5 is essential for TGF-β1-induced epithelial-mesenchymal transition and breast cancer progression
- (2013) Qian Liang et al. Scientific Reports
- Cyclin dependent kinases in cancer
- (2012) Miriam Canavese et al. CANCER BIOLOGY & THERAPY
- The Spindle Assembly Checkpoint
- (2012) Pablo Lara-Gonzalez et al. CURRENT BIOLOGY
- MYC pathway activation in triple-negative breast cancer is synthetic lethal with CDK inhibition
- (2012) Dai Horiuchi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Comprehensive molecular portraits of human breast tumours
- (2012) Daniel C. Koboldt et al. NATURE
- The hard facts
- (2012) Amy Maxmen NATURE
- Cyclin-dependent kinase control of the initiation-to-elongation switch of RNA polymerase II
- (2012) Stéphane Larochelle et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Cyclin K goes with Cdk12 and Cdk13
- (2012) Jiri Kohoutek et al. Cell Division
- Phase I study of PD 0332991, a cyclin-dependent kinase inhibitor, administered in 3-week cycles (Schedule 2/1)
- (2011) G K Schwartz et al. BRITISH JOURNAL OF CANCER
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Phase I, Dose-Escalation Trial of the Oral Cyclin-Dependent Kinase 4/6 Inhibitor PD 0332991, Administered Using a 21-Day Schedule in Patients with Advanced Cancer
- (2011) K. T. Flaherty et al. CLINICAL CANCER RESEARCH
- The Cyclin K/Cdk12 complex maintains genomic stability via regulation of expression of DNA damage response genes
- (2011) D. Blazek et al. GENES & DEVELOPMENT
- The CDK inhibitors in cancer research and therapy
- (2011) Jonas Cicenas et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Cdc14 phosphatase promotes segregation of telomeres through repression of RNA polymerase II transcription
- (2011) Andres Clemente-Blanco et al. NATURE CELL BIOLOGY
- CYY-1/Cyclin Y and CDK-5 Differentially Regulate Synapse Elimination and Formation for Rewiring Neural Circuits
- (2011) Mikyoung Park et al. NEURON
- Cdc14b regulates mammalian RNA polymerase II and represses cell cycle transcription
- (2011) María Guillamot et al. Scientific Reports
- Two Cyclin-Dependent Kinase Pathways Are Essential for Polarized Trafficking of Presynaptic Components
- (2010) Chan-Yen Ou et al. CELL
- CDK Inhibitors: From the Bench to Clinical Trials
- (2010) Flavio Rizzolio et al. CURRENT DRUG TARGETS
- Progressive Activation of CyclinB1-Cdk1 Coordinates Entry to Mitosis
- (2010) Olivier Gavet et al. DEVELOPMENTAL CELL
- Cell Cycle-dependent Regulation of the Forkhead Transcription Factor FOXK2 by CDK·Cyclin Complexes
- (2010) Anett Marais et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Therapeutic CDK4/6 inhibition in breast cancer: key mechanisms of response and failure
- (2010) J L Dean et al. ONCOGENE
- Emerging links between CDK cell cycle regulators and Wnt signaling
- (2010) Gary Davidson et al. TRENDS IN CELL BIOLOGY
- High cyclin B1 expression is associated with poor survival in breast cancer
- (2009) K Aaltonen et al. BRITISH JOURNAL OF CANCER
- A Conserved Phosphorylation Site within the Forkhead Domain of FoxM1B Is Required for Its Activation by Cyclin-CDK1
- (2009) Yi-Ju Chen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Phase II Study of Flavopiridol in Relapsed Chronic Lymphocytic Leukemia Demonstrating High Response Rates in Genetically High-Risk Disease
- (2009) Thomas S. Lin et al. JOURNAL OF CLINICAL ONCOLOGY
- TFIIH and P-TEFb Coordinate Transcription with Capping Enzyme Recruitment at Specific Genes in Fission Yeast
- (2009) Laia Viladevall et al. MOLECULAR CELL
- Identification of CDK10 as an Important Determinant of Resistance to Endocrine Therapy for Breast Cancer
- (2008) Elizabeth Iorns et al. CANCER CELL
- An Integrative Genomic and Proteomic Analysis of PIK3CA, PTEN, and AKT Mutations in Breast Cancer
- (2008) K. Stemke-Hale et al. CANCER RESEARCH
- Characterization of Cyclin L1 and L2 Interactions with CDK11 and Splicing Factors
- (2008) Pascal Loyer et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- CDK8 is a colorectal cancer oncogene that regulates β-catenin activity
- (2008) Ron Firestein et al. NATURE
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