标题
SMYD3: An Oncogenic Driver Targeting Epigenetic Regulation and Signaling Pathways
作者
关键词
-
出版物
Cancers
Volume 12, Issue 1, Pages 142
出版商
MDPI AG
发表日期
2020-01-06
DOI
10.3390/cancers12010142
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- ANKHD1 is required for SMYD3 to promote tumor metastasis in hepatocellular carcinoma
- (2019) Zhenyu Zhou et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Expression patterns and the prognostic value of the SMYD family members in human breast carcinoma using integrative bioinformatics analysis
- (2019) Jianping Song et al. Oncology Letters
- Small-molecule inhibitors of lysine methyltransferases SMYD2 and SMYD3: current trends
- (2019) Edoardo Fabini et al. Future Medicinal Chemistry
- Discovery of Irreversible Inhibitors Targeting Histone Methyltransferase, SMYD3
- (2019) Chuhui Huang et al. ACS Medicinal Chemistry Letters
- STAT3-induced SMYD3 transcription enhances chronic lymphocytic leukemia cell growth in vitro and in vivo
- (2019) Fujia Lin et al. INFLAMMATION RESEARCH
- A Novel lncRNA IHS Promotes Tumor Proliferation and Metastasis in HCC by Regulating the ERK- and AKT/GSK-3β-Signaling Pathways
- (2019) Zheng Chen et al. Molecular Therapy-Nucleic Acids
- Overexpression of the SMYD3 Promotes Proliferation, Migration, and Invasion of Pancreatic Cancer
- (2019) Cheng-lin Zhu et al. DIGESTIVE DISEASES AND SCIENCES
- SMYD3 promotes implant metastasis of ovarian cancer via H3K4 trimethylation of integrin promoters
- (2019) Tianjiao Lyu et al. INTERNATIONAL JOURNAL OF CANCER
- Lysine Methylation Regulators Moonlighting outside the Epigenome
- (2019) Evan M. Cornett et al. MOLECULAR CELL
- The SMYD3 methyltransferase promotes myogenesis by activating the myogenin regulatory network
- (2019) Roberta Codato et al. Scientific Reports
- SMYD3 controls a Wnt-responsive epigenetic switch for ASCL2 activation and cancer stem cell maintenance
- (2018) Tao Wang et al. CANCER LETTERS
- SMYD3 promoter hypomethylation is associated with the risk of colorectal cancer
- (2018) Bin Li et al. Future Oncology
- Small molecule inhibitors and CRISPR/Cas9 mutagenesis demonstrate that SMYD2 and SMYD3 activity are dispensable for autonomous cancer cell proliferation
- (2018) Michael J. Thomenius et al. PLoS One
- Notch ligand Delta-like 4 induces epigenetic regulation of Treg cell differentiation and function in viral infection
- (2018) Hung-An Ting et al. Mucosal Immunology
- SMYD3 promotes the epithelial–mesenchymal transition in breast cancer
- (2018) Claudio Fenizia et al. NUCLEIC ACIDS RESEARCH
- Smyd3-associated regulatory pathways in cancer
- (2017) Antonis Giakountis et al. SEMINARS IN CANCER BIOLOGY
- MiR-346 suppresses cell proliferation through SMYD3 dependent approach in hepatocellular carcinoma
- (2017) Weiyou Zhu et al. Oncotarget
- Protein lysine methyltransferase SMYD3 is involved in tumorigenesis through regulation of HER2 homodimerization
- (2017) Yuichiro Yoshioka et al. Cancer Medicine
- Network analyses elucidate the role of SMYD3 in esophageal squamous cell carcinoma
- (2017) Xinning Liu et al. FEBS Open Bio
- The long noncoding RNA SPRIGHTLY acts as an intranuclear organizing hub for pre-mRNA molecules
- (2017) Bongyong Lee et al. Science Advances
- ATM Signaling Pathway Is Implicated in the SMYD3-mediated Proliferation and Migration of Gastric Cancer Cells
- (2017) Lei Wang et al. Journal of Gastric Cancer
- Smyd3 open & closed lock mechanism for substrate recruitment: The hinge motion of C-terminal domain inferred from μ-second molecular dynamics simulations
- (2016) Balasubramanian Chandramouli et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Smyd3 Is a Transcriptional Potentiator of Multiple Cancer-Promoting Genes and Required for Liver and Colon Cancer Development
- (2016) Michalis E. Sarris et al. CANCER CELL
- SMYD3-Mediated H2A.Z.1 Methylation Promotes Cell Cycle and Cancer Proliferation
- (2016) C.-H. Tsai et al. CANCER RESEARCH
- EMT: 2016
- (2016) M. Angela Nieto et al. CELL
- Therapeutical potential of deregulated lysine methyltransferase SMYD3 as a safe target for novel anticancer agents
- (2016) Gurukumari Rajajeyabalachandran et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- SMYD3 stimulates EZR and LOXL2 transcription to enhance proliferation, migration, and invasion in esophageal squamous cell carcinoma
- (2016) Ying Zhu et al. HUMAN PATHOLOGY
- Structural Basis for Substrate Preference of SMYD3, a SET Domain-containing Protein Lysine Methyltransferase
- (2016) Weiqi Fu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Conformational Dynamics of Lysine Methyltransferase Smyd2. Insights into the Different Substrate Crevice Characteristics of Smyd2 and Smyd3
- (2016) Balasubramanian Chandramouli et al. Journal of Chemical Information and Modeling
- Structure-Based Design of a Novel SMYD3 Inhibitor that Bridges the SAM-and MEKK2-Binding Pockets
- (2016) Glenn S. Van Aller et al. STRUCTURE
- SMYD3-mediated lysine methylation in the PH domain is critical for activation of AKT1
- (2016) Yuichiro Yoshioka et al. Oncotarget
- RIZ1: a potential tumor suppressor in glioma
- (2015) Chenran Zhang et al. BMC CANCER
- Histone methyltransferase SMYD3 regulates the expression of transcriptional factors during bovine oocyte maturation and early embryonic development
- (2015) Haidong Bai et al. CYTOTECHNOLOGY
- A SMYD3 Small-Molecule Inhibitor Impairing Cancer Cell Growth
- (2015) Alessia Peserico et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Epigenetic control of Foxp3 by SMYD3 H3K4 histone methyltransferase controls iTreg development and regulates pathogenic T-cell responses during pulmonary viral infection
- (2015) D E de Almeida Nagata et al. Mucosal Immunology
- Cooperation between SMYD3 and PC4 drives a distinct transcriptional program in cancer cells
- (2015) Jin-Man Kim et al. NUCLEIC ACIDS RESEARCH
- SET and MYND domain-containing protein 3 is overexpressed in human glioma and contributes to tumorigenicity
- (2015) BIN DAI et al. ONCOLOGY REPORTS
- Overexpression of SMYD3 and matrix metalloproteinase-9 are associated with poor prognosis of patients with gastric cancer
- (2015) Yong Liu et al. TUMOR BIOLOGY
- Novel Oxindole Sulfonamides and Sulfamides: EPZ031686, the First Orally Bioavailable Small Molecule SMYD3 Inhibitor
- (2015) Lorna H. Mitchell et al. ACS Medicinal Chemistry Letters
- SMYD3 contributes to a more aggressive phenotype of prostate cancer and targets Cyclin D2 through H4K20me3
- (2015) Filipa Quintela Vieira et al. Oncotarget
- C-terminal domain of SMYD3 serves as a unique HSP90-regulated motif in oncogenesis
- (2015) Mark A. Brown et al. Oncotarget
- Genetic alterations of histone lysine methyltransferases and their significance in breast cancer
- (2015) Lanxin Liu et al. Oncotarget
- SMYD Proteins: Key Regulators in Skeletal and Cardiac Muscle Development and Function
- (2014) Shao Jun Du et al. Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology
- SMYD3 links lysine methylation of MAP3K2 to Ras-driven cancer
- (2014) Pawel K. Mazur et al. NATURE
- Effect of the downregulation of SMYD3 expression by RNAi on RIZ1 expression and proliferation of esophageal squamous cell carcinoma
- (2014) SHANG-WEN DONG et al. ONCOLOGY REPORTS
- Interplay between the Cancer Genome and Epigenome
- (2013) Hui Shen et al. CELL
- The methyltransferase SMYD3 mediates the recruitment of transcriptional cofactors at the myostatin and c-Met genes and regulates skeletal muscle atrophy
- (2013) V. Proserpio et al. GENES & DEVELOPMENT
- SMYD3 as an Oncogenic Driver in Prostate Cancer by Stimulation of Androgen Receptor Transcription
- (2013) Cheng Liu et al. JNCI-Journal of the National Cancer Institute
- A Comprehensive Survey of Ras Mutations in Cancer
- (2012) I. A. Prior et al. CANCER RESEARCH
- Cancer Epigenetics: From Mechanism to Therapy
- (2012) Mark A. Dawson et al. CELL
- Smyd3 regulates cancer cell phenotypes and catalyzes histone H4 lysine 5 methylation
- (2012) Glenn S. Van Aller et al. Epigenetics
- Epigenetic regulation of miR-124 by Hepatitis C Virus core protein promotes migration and invasion of intrahepatic cholangiocarcinoma cells by targeting SMYD3
- (2012) Bing Zeng et al. FEBS LETTERS
- Histone Lysine Methylation Dynamics: Establishment, Regulation, and Biological Impact
- (2012) Joshua C. Black et al. MOLECULAR CELL
- Intronic RNAs mediate EZH2 regulation of epigenetic targets
- (2012) Sònia Guil et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Perceiving the epigenetic landscape through histone readers
- (2012) Catherine A Musselman et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Knockdown of SMYD3 by RNA interference inhibits cervical carcinoma cell growth and invasion in vitro
- (2011) Shu-zhen Wang et al. BMB Reports
- SMYD3 Promotes Cancer Invasion by Epigenetic Upregulation of the Metalloproteinase MMP-9
- (2011) A. M. Cock-Rada et al. CANCER RESEARCH
- The Histone Modifications GoverningTFF1Transcription Mediated by Estrogen Receptor
- (2011) Yanyan Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structural and biochemical studies of human lysine methyltransferase Smyd3 reveal the important functional roles of its post-SET and TPR domains and the regulation of its activity by DNA binding
- (2011) Shutong Xu et al. NUCLEIC ACIDS RESEARCH
- Structural and Functional Profiling of the Human Histone Methyltransferase SMYD3
- (2011) Kenneth W. Foreman et al. PLoS One
- Smyd3 Is Required for the Development of Cardiac and Skeletal Muscle in Zebrafish
- (2011) Tomoaki Fujii et al. PLoS One
- The Language of Histone Crosstalk
- (2010) Jung-Shin Lee et al. CELL
- Structural Insights into the Autoinhibition and Posttranslational Activation of Histone Methyltransferase SmyD3
- (2010) Nualpun Sirinupong et al. JOURNAL OF MOLECULAR BIOLOGY
- Effects of SMYD3 over-expression on cell cycle acceleration and cell proliferation in MDA-MB-231 human breast cancer cells
- (2010) Tian-nian Ren et al. MEDICAL ONCOLOGY
- Knockdown of SMYD3 by RNA interference down-regulates c-Met expression and inhibits cells migration and invasion induced by HGF
- (2009) Jia-Ning Zou et al. CANCER LETTERS
- Secreted LOXL2 is a novel therapeutic target that promotes gastric cancer metastasis via the Src/FAK pathway
- (2009) Liang Peng et al. CARCINOGENESIS
- Requirement of Histone Methyltransferase SMYD3 for Estrogen Receptor-mediated Transcription
- (2009) Hyunjung Kim et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Association of the variable number of tandem repeats polymorphism in the promoter region of the SMYD3 gene with risk of esophageal squamous cell carcinoma in relation to tobacco smoking
- (2008) Haijian Wang et al. CANCER SCIENCE
- The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells
- (2008) Sendurai A. Mani et al. CELL
- The emerging field of dynamic lysine methylation of non-histone proteins
- (2008) Jing Huang et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search