Global Proteomic Analyses of STING‐Positive and ‐Negative Macrophages Reveal STING and Non‐STING Differentially Regulated Cellular and Molecular Pathways

Glycome and proteome components of Golgi membranes are common between two angiosperms with distinct cell wall structures

(2019) Ikenna O. Okekeogbu et al.   PLANT CELL

STING Polymer Structure Reveals Mechanisms for Activation, Hyperactivation, and Inhibition

(2019) Sabrina L. Ergun et al.   CELL

Suramin potently inhibits cGAMP synthase, cGAS, in THP1 cells to modulate IFN-β levels

(2018) Modi Wang et al.   Future Medicinal Chemistry

TMEM173 variants and potential importance to human biology and disease

(2018) Seema Patel et al.   GENES AND IMMUNITY

Galectin-3-binding protein: A multitask glycoprotein with innate immunity functions in viral and bacterial infections

(2018) Vuokko Loimaranta et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Targeting STING with covalent small-molecule inhibitors

(2018) Simone M. Haag et al.   NATURE

T-LAK cell-originated protein kinase (TOPK): an emerging target for cancer-specific therapeutics

(2018) Katharine J. Herbert et al.   Cell Death & Disease

Regulation of gingival epithelial cytokine response by bacterial cyclic dinucleotides

(2018) Samira Elmanfi et al.   Journal of Oral Microbiology

Cyclic Dinucleotides in Oral Bacteria and in Oral Biofilms

(2017) Ulvi K. Gürsoy et al.   Frontiers in Cellular and Infection Microbiology

Targeting sphingosine kinase 2 (SphK2) by ABC294640 inhibits colorectal cancer cell growth in vitro and in vivo

(2015) Cai Xun et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

STAM2, a member of the endosome-associated complex ESCRT-0 is highly expressed in neurons

(2015) Katarina Kapuralin et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

A secretory kinase complex regulates extracellular protein phosphorylation

(2015) Jixin Cui et al.   eLife

STING Ligand c-di-GMP Improves Cancer Vaccination against Metastatic Breast Cancer

(2014) D. Chandra et al.   Cancer Immunology Research

Molecular functions of the iron-regulated metastasis suppressor, NDRG1, and its potential as a molecular target for cancer therapy

(2013) Bernard A. Fang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Immune Responsive Gene 1 (IRG1) Promotes Endotoxin Tolerance by Increasing A20 Expression in Macrophages through Reactive Oxygen Species

(2013) Yingke Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING

(2013) Andrea Ablasser et al.   NATURE

Pivotal Roles of cGAS-cGAMP Signaling in Antiviral Defense and Immune Adjuvant Effects

(2013) X.-D. Li et al.   SCIENCE

Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway

(2012) L. Sun et al.   SCIENCE

Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment

(2011) Jürgen Cox et al.   JOURNAL OF PROTEOME RESEARCH

Mannose-6-phosphate pathway: A review on its role in lysosomal function and dysfunction

(2011) Maria Francisca Coutinho et al.   MOLECULAR GENETICS AND METABOLISM

A lipid binding domain in sphingosine kinase 2

(2009) Anthony S. Don et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

c-Abl and Src-family kinases cross-talk in regulation of myeloid cell migration

(2009) Anna Baruzzi et al.   FEBS LETTERS

An integrated approach for measuring copy number variation at theFCGR3(CD16) locus

(2009) Edward J. Hollox et al.   HUMAN MUTATION

STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

(2009) Hiroki Ishikawa et al.   NATURE

A practical guide to the MaxQuant computational platform for SILAC-based quantitative proteomics

(2009) Jürgen Cox et al.   Nature Protocols

Regulation of Histone Acetylation in the Nucleus by Sphingosine-1-Phosphate

(2009) N. C. Hait et al.   SCIENCE

Hematopoietic cell kinase (Hck) isoforms and phagocyte duties – From signaling and actin reorganization to migration and phagocytosis

(2008) R GUIET et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

(2008) Hiroki Ishikawa et al.   NATURE

MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification

(2008) Jürgen Cox et al.   NATURE BIOTECHNOLOGY