Regulation of gingival epithelial cytokine response by bacterial cyclic dinucleotides

The ER membrane adaptor ERAdP senses the bacterial second messenger c-di-AMP and initiates anti-bacterial immunity

(2018) Pengyan Xia et al.   NATURE IMMUNOLOGY

Regulating STING in health and disease

(2017) Yang Li et al.   Journal of Inflammation-London

Cyclic Dinucleotides in Oral Bacteria and in Oral Biofilms

(2017) Ulvi K. Gürsoy et al.   Frontiers in Cellular and Infection Microbiology

c-di-AMP: An Essential Molecule in the Signaling Pathways that Regulate the Viability and Virulence of Gram-Positive Bacteria

(2017) Tazin Fahmi et al.   Genes

Regulation of oxidative response and extracellular polysaccharide synthesis by a diadenylate cyclase in S treptococcus mutans

(2015) Xingqun Cheng et al.   ENVIRONMENTAL MICROBIOLOGY

A jack of all trades: the multiple roles of the unique essential second messenger cyclic di-AMP

(2015) Fabian M. Commichau et al.   MOLECULAR MICROBIOLOGY

A bacterial cyclic dinucleotide activates the cytosolic surveillance pathway and mediates innate resistance to tuberculosis

(2015) Bappaditya Dey et al.   NATURE MEDICINE

Trained Immunity or Tolerance: Opposing Functional Programs Induced in Human Monocytes after Engagement of Various Pattern Recognition Receptors

(2014) Daniela C. Ifrim et al.   Clinical and Vaccine Immunology

Identification of a Diguanylate Cyclase and Its Role in Porphyromonas gingivalis Virulence

(2014) Swarnava Chaudhuri et al.   INFECTION AND IMMUNITY

Cyclic Dinucleotides and the Innate Immune Response

(2013) Olga Danilchanka et al.   CELL

Inactivation of Cyclic Di-GMP Binding Protein TDE0214 Affects the Motility, Biofilm Formation, and Virulence of Treponema denticola

(2013) J. Bian et al.   JOURNAL OF BACTERIOLOGY

MPYS/STING-Mediated TNF- , Not Type I IFN, Is Essential for the Mucosal Adjuvant Activity of (3'-5')-Cyclic-Di-Guanosine-Monophosphate In Vivo

(2013) S. M. Blaauboer et al.   JOURNAL OF IMMUNOLOGY

Cyclic di-GMP: the First 25 Years of a Universal Bacterial Second Messenger

(2013) U. Romling et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

STING Recognition of Cytoplasmic DNA Instigates Cellular Defense

(2013) Takayuki Abe et al.   MOLECULAR CELL

Nucleotide, c-di-GMP, c-di-AMP, cGMP, cAMP, (p)ppGpp signaling in bacteria and implications in pathogenesis

(2012) Dimpy Kalia et al.   CHEMICAL SOCIETY REVIEWS

STING Specifies IRF3 Phosphorylation by TBK1 in the Cytosolic DNA Signaling Pathway

(2012) Y. Tanaka et al.   Science Signaling

Low-Abundance Biofilm Species Orchestrates Inflammatory Periodontal Disease through the Commensal Microbiota and Complement

(2011) George Hajishengallis et al.   Cell Host & Microbe

Porphyromonas gingivalis lipopolysaccharide lipid A heterogeneity differentially modulates the expression of IL-6 and IL-8 in human gingival fibroblasts

(2011) Thanuja D. K. Herath et al.   JOURNAL OF CLINICAL PERIODONTOLOGY

Molecular Signaling Mechanisms of the Periopathogen, Treponema denticola

(2011) J.R. Frederick et al.   JOURNAL OF DENTAL RESEARCH

Immune Recognition of Gene Transfer Vectors: Focus on Adenovirus as a Paradigm

(2011) Yasser Ali Aldhamen et al.   Frontiers in Immunology

Cyclic di-nucleotides: new era for small molecules as adjuvants

(2011) Rimma Libanova et al.   Microbial Biotechnology

Cyclic di-GMP Signaling Regulates Invasion by Ehrlichia chaffeensis of Human Monocytes

(2010) Y. Kumagai et al.   JOURNAL OF BACTERIOLOGY

One-Flask Syntheses of c-di-GMP and the [Rp,Rp] and [Rp,Sp] Thiophosphate Analogues

(2010) Barbara L. Gaffney et al.   ORGANIC LETTERS

Microbial shift and periodontitis

(2010) Alex B. Berezow et al.   PERIODONTOLOGY 2000

c-di-AMP Secreted by Intracellular Listeria monocytogenes Activates a Host Type I Interferon Response

(2010) J. J. Woodward et al.   SCIENCE

3′,5′-Cyclic diguanylic acid elicits mucosal immunity against bacterial infection

(2009) Hongbin Yan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP

(2009) Sarah M. McWhirter et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The effect of c-di-GMP (3′–5′-cyclic diguanylic acid) on the biofilm formation and adherence of Streptococcus mutans

(2009) Wenjuan Yan et al.   MICROBIOLOGICAL RESEARCH

Host immune responses to Porphyromonas gingivalis antigens

(2009) Rishi D. Pathirana et al.   PERIODONTOLOGY 2000

ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization

(2009) W. Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HORMESIS: WHY IT IS IMPORTANT TO TOXICOLOGY AND TOXICOLOGISTS

(2008) Edward J. Calabrese   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Pro-inflammatory cytokine release in keratinocytes is mediated through the MAPK signal-integrating kinases

(2008) Rasmus Boye Kjellerup et al.   EXPERIMENTAL DERMATOLOGY

Cyclic Di-GMP (c-Di-GMP) Goes in1593to Host Cells—c-Di-GMP Signaling in the Obligate Intracellular PathogenAnaplasma phagocytophilum

(2008) Ute Römling   JOURNAL OF BACTERIOLOGY

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

(2008) Hiroki Ishikawa et al.   NATURE

Great Times for Small Molecules: c-di-AMP, a Second Messenger Candidate in Bacteria and Archaea

(2008) U. Romling   Science Signaling

c-di-GMP is an effective immunomodulator and vaccine adjuvant against pneumococcal infection

(2008) Abiodun D. Ogunniyi et al.   VACCINE

Immunohistochemical localization of Toll-like receptors 1-10 in periodontitis

(2008) A. Beklen et al.   Oral microbiology and immunology

The host cytokine response toPorphyromonas gingivalisis modified by gingipains

(2008) P. G. Stathopoulou et al.   Oral microbiology and immunology