Alterations in platelet behavior after major trauma: adaptive or maladaptive?

Contractile forces in platelet aggregates under microfluidic shear gradients reflect platelet inhibition and bleeding risk

(2019) Lucas H. Ting et al.   Nature Communications

Evaluation of a lyophilized platelet‐derived hemostatic product

(2019) James A. Bynum et al.   TRANSFUSION

Platelet‐derived extracellular vesicles released after trauma promote hemostasis and contribute to DVT in mice

(2019) Mitchell R. Dyer et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Platelet Inflammatory Response to Stress

(2019) Fabrice Cognasse et al.   Frontiers in Immunology

Histone H4 induces platelet ballooning and microparticle release during trauma hemorrhage

(2019) Paul Vulliamy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intravenous administration of synthetic platelets (SynthoPlate) in a mouse liver injury model of uncontrolled hemorrhage improves hemostasis

(2018) Mitchell R. Dyer et al.   Journal of Trauma and Acute Care Surgery

Perhaps It’s Not the Platelet

(2018) Lucy Z Kornblith et al.   Journal of Trauma and Acute Care Surgery

Innate immune responses to trauma

(2018) Markus Huber-Lang et al.   NATURE IMMUNOLOGY

Macrophage extracellular trap formation promoted by platelet activation is a key mediator of rhabdomyolysis-induced acute kidney injury

(2018) Koshu Okubo et al.   NATURE MEDICINE

Hemorrhagic Shock

(2018) Jeremy W. Cannon   NEW ENGLAND JOURNAL OF MEDICINE

Platelet-Derived Microvesicles

(2018) Ernesto Lopez et al.   SHOCK

Deep vein thrombosis in mice is regulated by platelet HMGB1 through release of neutrophil-extracellular traps and DNA

(2018) Mitchell R. Dyer et al.   Scientific Reports

Intravenous synthetic platelet (SynthoPlate) nanoconstructs reduce bleeding and improve ‘golden hour’ survival in a porcine model of traumatic arterial hemorrhage

(2018) DaShawn A. Hickman et al.   Scientific Reports

Splicing of platelet resident pre-mRNAs upon activation by physiological stimuli results in functionally relevant proteome modifications

(2018) Giovanni Nassa et al.   Scientific Reports

Intravenous administration of synthetic platelets (SynthoPlate) in a mouse liver injury model of uncontrolled hemorrhage improves hemostasis

(2018) Mitchell R. Dyer et al.   Journal of Trauma and Acute Care Surgery

Perhaps It’s Not the Platelet

(2018) Lucy Z Kornblith et al.   Journal of Trauma and Acute Care Surgery

Assessment of Platelet Function in Traumatic Brain Injury—A Retrospective Observational Study in the Neuro-Critical Care Setting

(2018) Caroline Lindblad et al.   Frontiers in Neurology

Platelet microparticles sustain autophagy-associated activation of neutrophils in systemic sclerosis

(2018) Norma Maugeri et al.   Science Translational Medicine

ADAMTS13: origins, applications, and prospects

(2018) William E. Plautz et al.   TRANSFUSION

Platelet dysfunction during trauma involves diverse signaling pathways and an inhibitory activity in patient-derived plasma

(2018) Christopher C. Verni et al.   Journal of Trauma and Acute Care Surgery

Platelet toll-like receptors in thromboinflammation

(2017) Mirta Schattner   Frontiers in Bioscience-Landmark

Assessment of three point-of-care platelet function assays in adult trauma patients

(2017) Christopher Robert Connelly et al.   JOURNAL OF SURGICAL RESEARCH

Impact of blood products on platelet function in patients with traumatic injuries: a translational study

(2017) Hanne Hee Henriksen et al.   JOURNAL OF SURGICAL RESEARCH

Syndecan-1: A Quantitative Marker for the Endotheliopathy of Trauma

(2017) Erika Gonzalez Rodriguez et al.   JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS

In vitrocharacterization of SynthoPlate™ (synthetic platelet) technology and itsin vivoevaluation in severely thrombocytopenic mice

(2017) M. Shukla et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Soluble fibrin causes an acquired platelet glycoprotein VI signaling defect: implications for coagulopathy

(2017) M. Y. Lee et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Fibrinolysis shutdown is associated with a fivefold increase in mortality in trauma patients lacking hypersensitivity to tissue plasminogen activator

(2017) Hunter B. Moore et al.   Journal of Trauma and Acute Care Surgery

High ratio plasma resuscitation does not improve survival in pediatric trauma patients

(2017) Jeremy W. Cannon et al.   Journal of Trauma and Acute Care Surgery

Acute traumatic coagulopathy

(2017) Michael A. Meledeo et al.   Journal of Trauma and Acute Care Surgery

Platelet transfusions reduce fibrinolysis but do not restore platelet function during trauma hemorrhage

(2017) Paul Vulliamy et al.   Journal of Trauma and Acute Care Surgery

Nonhuman primate model of polytraumatic hemorrhagic shock recapitulates early platelet dysfunction observed following severe injury in humans

(2017) Leasha J. Schaub et al.   Journal of Trauma and Acute Care Surgery

Endotheliopathy is associated with higher levels of cell-free DNA following major trauma: A prospective observational study

(2017) David N. Naumann et al.   PLoS One

Platelet adenosine diphosphate receptor inhibition provides no advantage in predicting need for platelet transfusion or massive transfusion

(2017) Gregory R. Stettler et al.   SURGERY

Platelet storage performance is consistent by donor: a pilot study comparing “good” and “poor” storing platelets

(2017) Ido J. Bontekoe et al.   TRANSFUSION

Multiplate and TEG platelet mapping in a population of severely injured trauma patients

(2017) M. J. George et al.   TRANSFUSION MEDICINE

Membrane Ballooning in Aggregated Platelets is Synchronised and Mediates a Surge in Microvesiculation

(2017) Ejaife O. Agbani et al.   Scientific Reports

Signatures of inflammation and impending multiple organ dysfunction in the hyperacute phase of trauma: A prospective cohort study

(2017) Claudia P. Cabrera et al.   PLOS MEDICINE

Fibrinolysis shutdown is associated with a fivefold increase in mortality in trauma patients lacking hypersensitivity to tissue plasminogen activator

(2017) Hunter B. Moore et al.   Journal of Trauma and Acute Care Surgery

High ratio plasma resuscitation does not improve survival in pediatric trauma patients

(2017) Jeremy W. Cannon et al.   Journal of Trauma and Acute Care Surgery

Acute traumatic coagulopathy

(2017) Michael A. Meledeo et al.   Journal of Trauma and Acute Care Surgery

Platelet transfusions reduce fibrinolysis but do not restore platelet function during trauma hemorrhage

(2017) Paul Vulliamy et al.   Journal of Trauma and Acute Care Surgery

Nonhuman primate model of polytraumatic hemorrhagic shock recapitulates early platelet dysfunction observed following severe injury in humans

(2017) Leasha J. Schaub et al.   Journal of Trauma and Acute Care Surgery

Association of Mechanism of Injury With Risk for Venous Thromboembolism After Trauma

(2017) Charles A. Karcutskie et al.   JAMA Surgery

NF-κB Links TLR2 and PAR1 to Soluble Immunomodulator Factor Secretion in Human Platelets

(2017) Pauline Damien et al.   Frontiers in Immunology

Platelet activation and dysfunction in a large-animal model of traumatic brain injury and hemorrhage

(2017) Martin Sillesen et al.   Journal of Trauma and Acute Care Surgery

Platelet-derived high-mobility group box 1 promotes recruitment and suppresses apoptosis of monocytes

(2016) Sebastian Vogel et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Disulfide HMGB1 derived from platelets coordinates venous thrombosis in mice

(2016) K. Stark et al.   BLOOD

Advances in the understanding of trauma-induced coagulopathy

(2016) R. Chang et al.   BLOOD

Acute Fibrinolysis Shutdown after Injury Occurs Frequently and Increases Mortality: A Multicenter Evaluation of 2,540 Severely Injured Patients

(2016) Hunter B. Moore et al.   JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS

Modulating the endotheliopathy of trauma

(2016) Shibani Pati et al.   Journal of Trauma and Acute Care Surgery

Inhibition of platelet function is common following even minor injury

(2016) Sarah Sirajuddin et al.   Journal of Trauma and Acute Care Surgery

Ex vivo recapitulation of trauma-induced coagulopathy and preliminary assessment of trauma patient platelet function under flow using microfluidic technology

(2016) Ruizhi Li et al.   Journal of Trauma and Acute Care Surgery

Platelet transfusion versus standard care after acute stroke due to spontaneous cerebral haemorrhage associated with antiplatelet therapy (PATCH): a randomised, open-label, phase 3 trial

(2016) M Irem Baharoglu et al.   LANCET

The effects of 22°C and 4°C storage of platelets on vascular endothelial integrity and function

(2016) Gyulnar Baimukanova et al.   TRANSFUSION

Platelets regulate vascular endothelial stability: assessing the storage lesion and donor variability of apheresis platelets

(2016) Gyulnar Baimukanova et al.   TRANSFUSION

Current Pathological and Laboratory Considerations in the Diagnosis of Disseminated Intravascular Coagulation

(2016) Cheng-Hock Toh et al.   Annals of Laboratory Medicine

Inhibition of platelet function is common following even minor injury

(2016) Sarah Sirajuddin et al.   Journal of Trauma and Acute Care Surgery

Ex vivo recapitulation of trauma-induced coagulopathy and preliminary assessment of trauma patient platelet function under flow using microfluidic technology

(2016) Ruizhi Li et al.   Journal of Trauma and Acute Care Surgery

Modulating the endotheliopathy of trauma

(2016) Shibani Pati et al.   Journal of Trauma and Acute Care Surgery

Metformin Uniquely Prevents Thrombosis by Inhibiting Platelet Activation and mtDNA Release

(2016) Guang Xin et al.   Scientific Reports

Activated platelet–T-cell conjugates in peripheral blood of patients with HIV infection

(2015) Samantha A. Green et al.   AIDS

Plasminogen associates with phosphatidylserine-exposing platelets and contributes to thrombus lysis under flow

(2015) C. S. Whyte et al.   BLOOD

Coordinated Membrane Ballooning and Procoagulant Spreading in Human PlateletsClinical Perspective

(2015) Ejaife O. Agbani et al.   CIRCULATION

Imaging the dynamic platelet-neutrophil response in sterile liver injury and repair in mice

(2015) Ingrid Slaba et al.   HEPATOLOGY

Circulating levels of platelet α-granule cytokines in trauma patients

(2015) N. A. Windeløv et al.   INFLAMMATION RESEARCH

The global burden of injury: incidence, mortality, disability-adjusted life years and time trends from the Global Burden of Disease study 2013

(2015) Juanita A Haagsma et al.   INJURY PREVENTION

Transfusion of Plasma, Platelets, and Red Blood Cells in a 1:1:1 vs a 1:1:2 Ratio and Mortality in Patients With Severe Trauma

(2015) John B. Holcomb et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Platelet-derived HMGB1 is a critical mediator of thrombosis

(2015) Sebastian Vogel et al.   JOURNAL OF CLINICAL INVESTIGATION

Mediators and molecular pathways involved in the regulation of neutrophil extracellular trap formation mediated by activated platelets

(2015) Agostina Carestia et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Platelet dysfunction and platelet transfusion in traumatic brain injury

(2015) Alexandra Briggs et al.   JOURNAL OF SURGICAL RESEARCH

Desmopressin treatment improves platelet function under flow in patients with postoperative bleeding

(2015) F. Swieringa et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Viscoelastic measurements of platelet function, not fibrinogen function, predicts sensitivity to tissue-type plasminogen activator in trauma patients

(2015) H. B. Moore et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Regulation of the genetic code in megakaryocytes and platelets

(2015) M. T. Rondina et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Can we ever stop worrying about venous thromboembolism after trauma?

(2015) Laura N. Godat et al.   Journal of Trauma and Acute Care Surgery

Thrombin generation and procoagulant microparticle profiles after acute trauma

(2015) Myung S. Park et al.   Journal of Trauma and Acute Care Surgery

Fresh frozen plasma and spray-dried plasma mitigate pulmonary vascular permeability and inflammation in hemorrhagic shock

(2015) Daniel R. Potter et al.   Journal of Trauma and Acute Care Surgery

Comparison of Aggregometry with Flow Cytometry for the Assessment of Agonists´-Induced Platelet Reactivity in Patients on Dual Antiplatelet Therapy

(2015) Thomas Gremmel et al.   PLoS One

Hemolysis Exacerbates Hyperfibrinolysis, Whereas Platelolysis Shuts Down Fibrinolysis

(2015) Hunter B. Moore et al.   SHOCK

Platelet components associated with adverse reactions: predictive value of mitochondrial DNA relative to biological response modifiers

(2015) Fabrice Cognasse et al.   TRANSFUSION

Haemostatic function and biomarkers of endothelial damage before and after platelet transfusion in patients with acute myeloid leukaemia

(2015) A. M. Larsen et al.   TRANSFUSION MEDICINE

Can we ever stop worrying about venous thromboembolism after trauma?

(2015) Laura N. Godat et al.   Journal of Trauma and Acute Care Surgery

Thrombin generation and procoagulant microparticle profiles after acute trauma

(2015) Myung S. Park et al.   Journal of Trauma and Acute Care Surgery

Fresh frozen plasma and spray-dried plasma mitigate pulmonary vascular permeability and inflammation in hemorrhagic shock

(2015) Daniel R. Potter et al.   Journal of Trauma and Acute Care Surgery

Genetic Deletion of Toll-Like Receptor 4 on Platelets Attenuates Experimental Pulmonary Hypertension

(2014) Eileen M. Bauer et al.   CIRCULATION RESEARCH

FLow-Induced PRotrusions (FLIPRs)

(2014) Claudia Tersteeg et al.   CIRCULATION RESEARCH

Toll-Like Receptor 4 Regulates Platelet Function and Contributes to Coagulation Abnormality and Organ Injury in Hemorrhagic Shock and Resuscitation

(2014) N. Ding et al.   Circulation-Cardiovascular Genetics

Treatment with a histone deacetylase inhibitor, valproic acid, is associated with increased platelet activation in a large animal model of traumatic brain injury and hemorrhagic shock

(2014) Simone E. Dekker et al.   JOURNAL OF SURGICAL RESEARCH

Platelets provoke distinct dynamics of immune responses by differentially regulating CD4+T-cell proliferation

(2014) L. Zhu et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Activated platelets present high mobility group box 1 to neutrophils, inducing autophagy and promoting the extrusion of neutrophil extracellular traps

(2014) N. Maugeri et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Hypercoagulability and other risk factors in trauma intensive care unit patients with venous thromboembolism

(2014) Robert M. Van Haren et al.   Journal of Trauma and Acute Care Surgery

The systemic immune response to trauma: an overview of pathophysiology and treatment

(2014) Janet M Lord et al.   LANCET

Release and activity of histone in diseases

(2014) R Chen et al.   Cell Death & Disease

A Randomized Controlled Pilot Trial of Modified Whole Blood Versus Component Therapy in Severely Injured Patients Requiring Large Volume Transfusions

(2013) Bryan A. Cotton et al.   ANNALS OF SURGERY

Oxidative Stress Elicits Platelet/Leukocyte Inflammatory Interactions via HMGB1: A Candidate for Microvessel Injury in Sytemic Sclerosis

(2013) Norma Maugeri et al.   ANTIOXIDANTS & REDOX SIGNALING

In vitro and in vivo hemostatic capabilities of a functionally integrated platelet-mimetic liposomal nanoconstruct

(2013) Christa L. Modery-Pawlowski et al.   BIOMATERIALS

Functional consequences of platelet binding to T lymphocytes in inflammation

(2013) Carlos Zamora et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Early Platelet Dysfunction in a Rodent Model of Blunt Traumatic Brain Injury Reflects the Acute Traumatic Coagulopathy Found in Humans

(2013) Deborah L. Donahue et al.   JOURNAL OF NEUROTRAUMA

Increased platelet storage time is associated with mitochondrial dysfunction and impaired platelet function

(2013) José Paul Perales Villarroel et al.   JOURNAL OF SURGICAL RESEARCH

A prospective evaluation of platelet function in patients on antiplatelet therapy with traumatic intracranial hemorrhage

(2013) Bellal Joseph et al.   Journal of Trauma and Acute Care Surgery

Persistent inflammation, immunosuppression, and catabolism syndrome after severe blunt trauma

(2013) Erin L. Vanzant et al.   Journal of Trauma and Acute Care Surgery

Response to antiplatelet therapy is independent of endogenous thrombin generation potential

(2013) Thomas Gremmel et al.   THROMBOSIS RESEARCH

Regulation of platelet responses triggered by Toll-like receptor 2 and 4 ligands is another non-genomic role of nuclear factor-kappaB

(2013) Leonardo Rivadeneyra et al.   THROMBOSIS RESEARCH

Circulating Histones Are Mediators of Trauma-associated Lung Injury

(2012) Simon T. Abrams et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Circulating platelets as a source of the damage-associated molecular pattern HMGB1 in patients with systemic sclerosis

(2012) Norma Maugeri et al.   AUTOIMMUNITY

Plasma angiopoietin-2 in clinical acute lung injury

(2012) Carolyn S. Calfee et al.   CRITICAL CARE MEDICINE

Platelets induce neutrophil extracellular traps in transfusion-related acute lung injury

(2012) Axelle Caudrillier et al.   JOURNAL OF CLINICAL INVESTIGATION

Histones from Dying Renal Cells Aggravate Kidney Injury via TLR2 and TLR4

(2012) R. Allam et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The incidence and magnitude of fibrinolytic activation in trauma patients

(2012) I. RAZA et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Utility of platelet transfusion in adult patients with traumatic intracranial hemorrhage and preinjury antiplatelet use

(2012) Daniel K. Nishijima et al.   Journal of Trauma and Acute Care Surgery

Characterization of platelet dysfunction after trauma

(2012) Matthew E. Kutcher et al.   Journal of Trauma and Acute Care Surgery

Platelet Dysfunction is an Early Marker for Traumatic Brain Injury-Induced Coagulopathy

(2012) Patrick K. Davis et al.   Neurocritical Care

Alterations of platelet function and clot formation kinetics after in vitro exposure to anti-A and -B

(2012) Majed A. Refaai et al.   TRANSFUSION

The clinical significance of platelet counts in the first 24 hours after severe injury

(2012) Lynn G. Stansbury et al.   TRANSFUSION

The Prospective, Observational, Multicenter, Major Trauma Transfusion (PROMMTT) Study

(2012) John B. Holcomb et al.   JAMA Surgery

Critical Role of Activated Protein C in Early Coagulopathy and Later Organ Failure, Infection and Death in Trauma Patients

(2011) Mitchell Jay Cohen et al.   ANNALS OF SURGERY

Trauma alarmins as activators of damage-induced inflammation

(2011) J. Manson et al.   BRITISH JOURNAL OF SURGERY

Functional definition and characterization of acute traumatic coagulopathy

(2011) Ross Davenport et al.   CRITICAL CARE MEDICINE

Toll-like receptors

(2011) Eva Marie Y. Moresco et al.   CURRENT BIOLOGY

The role of toll-like receptor-4 in the development of multi-organ failure following traumatic haemorrhagic shock and resuscitation

(2011) Lee J. McGhan et al.   INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED

A genomic storm in critically injured humans

(2011) Wenzhong Xiao et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Lipopolysaccharide Signaling without a Nucleus: Kinase Cascades Stimulate Platelet Shedding of Proinflammatory IL-1 -Rich Microparticles

(2011) G. T. Brown et al.   JOURNAL OF IMMUNOLOGY

High sCD40L levels early after trauma are associated with enhanced shock, sympathoadrenal activation, tissue and endothelial damage, coagulopathy and mortality

(2011) P. I. JOHANSSON et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Assessment of platelet transfusion for reversal of aspirin after traumatic brain injury

(2011) Arshad M. Bachelani et al.   SURGERY

An association of ABO non-identical platelet and cryoprecipitate transfusions with altered red cell transfusion needs in surgical patients

(2011) Majed A. Refaai et al.   VOX SANGUINIS

Understanding and Evaluating Platelet Function

(2011) L. Brass   Hematology-American Society of Hematology Education Program

High Ratios of Plasma and Platelets to Packed Red Blood Cells Do Not Affect Mortality in Nonmassively Transfused Patients

(2011) Chitra N. Sambasivan et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

A Normal Platelet Count May Not Be Enough: The Impact of Admission Platelet Count on Mortality and Transfusion in Severely Injured Trauma Patients

(2011) Lisa M. Brown et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Increased Platelet:RBC Ratios Are Associated With Improved Survival After Massive Transfusion

(2011) John B. Holcomb et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Ratio of angiopoietin-2 to angiopoietin-1 as a predictor of mortality in acute lung injury patients

(2010) Thida Ong et al.   CRITICAL CARE MEDICINE

Tranexamic acid partially improves platelet function in patients treated with dual antiplatelet therapy

(2010) Christian F Weber et al.   EUROPEAN JOURNAL OF ANAESTHESIOLOGY

Intracellular Toll-like Receptors

(2010) Amanda L. Blasius et al.   IMMUNITY

The Impact of Platelet Transfusion in Massively Transfused Trauma Patients

(2010) Kenji Inaba et al.   JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS

Platelets as Central Mediators of Systemic Inflammatory Responses

(2010) Tammy L. Smith et al.   THROMBOSIS RESEARCH

The Impact of Platelets on the Progression of Traumatic Intracranial Hemorrhage

(2010) Beat Schnüriger et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Platelet membrane proteomics: a novel repository for functional research

(2009) U. Lewandrowski et al.   BLOOD

Toll-like receptors 4 contribute to endothelial injury and inflammation in hemorrhagic shock in mice

(2009) Ygal Benhamou et al.   CRITICAL CARE MEDICINE

Coagulopathy in trauma patients: importance of thrombocyte function?

(2009) Ross A Davenport et al.   Current Opinion in Anesthesiology

Lipopolysaccharide Stimulates Platelet Secretion and Potentiates Platelet Aggregation via TLR4/MyD88 and the cGMP-Dependent Protein Kinase Pathway

(2009) G. Zhang et al.   JOURNAL OF IMMUNOLOGY

Warm Fresh Whole Blood Is Independently Associated With Improved Survival for Patients With Combat-Related Traumatic Injuries

(2009) Philip C. Spinella et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

An Evaluation of the Impact of Apheresis Platelets Used in the Setting of Massively Transfused Trauma Patients

(2009) Jeremy G. Perkins et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Amicus or Adversary

(2008) Fernando A. Bozza et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Toll-like receptor 4 ligand can differentially modulate the release of cytokines by human platelets

(2008) Fabrice Cognasse et al.   BRITISH JOURNAL OF HAEMATOLOGY

Platelets, Petechiae, and Preservation of the Vascular Wall

(2008) Ralph L. Nachman et al.   NEW ENGLAND JOURNAL OF MEDICINE