标题
Metabolism of pancreatic cancer: paving the way to better anticancer strategies
作者
关键词
-
出版物
Molecular Cancer
Volume 19, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2020-03-02
DOI
10.1186/s12943-020-01169-7
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Cancer statistics, 2019
- (2019) Rebecca L. Siegel et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Acetyl-CoA metabolism supports multi-step pancreatic tumorigenesis
- (2019) Alessandro Carrer et al. Cancer Discovery
- Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers
- (2019) Conan G. Kinsey et al. NATURE MEDICINE
- Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer
- (2019) Kirsten L. Bryant et al. NATURE MEDICINE
- Topical Diclofenac Reprograms Metabolism and Immune Cell Infiltration in Actinic Keratosis
- (2019) Katrin Singer et al. Frontiers in Oncology
- Altered Gene Expression along the Glycolysis–Cholesterol Synthesis Axis Is Associated with Outcome in Pancreatic Cancer
- (2019) Joanna M. Karasinska et al. CLINICAL CANCER RESEARCH
- Modulation of redox metabolism negates cancer-associated fibroblasts-induced treatment resistance in a heterotypic 3D culture platform of pancreatic cancer
- (2019) Mans Broekgaarden et al. BIOMATERIALS
- Metabolic Subtyping for Novel Personalized Therapies Against Pancreatic Cancer
- (2019) Kamiya Mehla et al. CLINICAL CANCER RESEARCH
- Real‐world outcomes of FOLFIRINOX vs gemcitabine and nab‐paclitaxel in advanced pancreatic cancer: A population‐based propensity score‐weighted analysis
- (2019) Kelvin K. W. Chan et al. Cancer Medicine
- FOLFIRINOX Versus Gemcitabine/Nab-Paclitaxel for Neoadjuvant Treatment of Resectable and Borderline Resectable Pancreatic Head Adenocarcinoma
- (2018) Mashaal Dhir et al. ANNALS OF SURGICAL ONCOLOGY
- Survival of the fittest: Cancer challenges T cell metabolism
- (2018) Davide G. Franchina et al. CANCER LETTERS
- Oxidative Phosphorylation as an Emerging Target in Cancer Therapy
- (2018) Thomas M. Ashton et al. CLINICAL CANCER RESEARCH
- Pyruvate Kinase Isozyme M2 Plays a Critical Role in the Interactions Between Pancreatic Stellate Cells and Cancer Cells
- (2018) Atsushi Masamune et al. DIGESTIVE DISEASES AND SCIENCES
- Molecular targeted therapy: treating cancer with specificity
- (2018) Yeuan Ting Lee et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- MiR-21-mediated Metabolic Alteration of Cancer-associated Fibroblasts and Its Effect on Pancreatic Cancer Cell Behavior
- (2018) Shuo Chen et al. International Journal of Biological Sciences
- Durable Remissions with Ivosidenib in IDH1-Mutated Relapsed or Refractory AML
- (2018) Courtney D. DiNardo et al. NEW ENGLAND JOURNAL OF MEDICINE
- The responsively decreased PKM2 facilitates the survival of pancreatic cancer cells in hypoglucose
- (2018) Xiang Li et al. Cell Death & Disease
- Tumor-associated macrophages promote progression and the Warburg effect via CCL18/NF-kB/VCAM-1 pathway in pancreatic ductal adenocarcinoma
- (2018) Huilin Ye et al. Cell Death & Disease
- USP9X inhibition improves gemcitabine sensitivity in pancreatic cancer by inhibiting autophagy
- (2018) Tao Ma et al. CANCER LETTERS
- Paracrine HGF/c-MET enhances the stem cell-like potential and glycolysis of pancreatic cancer cells via activation of YAP/HIF-1α
- (2018) Bin Yan et al. EXPERIMENTAL CELL RESEARCH
- Rescue of 2-Deoxyglucose Side Effects by Ketogenic Diet
- (2018) Martin Voss et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Tumor microenvironment participates in metastasis of pancreatic cancer
- (2018) Bo Ren et al. Molecular Cancer
- Omega-3 Fatty Acids Prevent Early Pancreatic Carcinogenesis via Repression of the AKT Pathway
- (2018) Yongzeng Ding et al. Nutrients
- The Potential of CAR T Cell Therapy in Pancreatic Cancer
- (2018) Mehmet Akce et al. Frontiers in Immunology
- Significance of 18F-Fluorodeoxyglucose (FDG) Uptake in Response to Chemoradiotherapy for Pancreatic Cancer
- (2018) Hiroshi Kurahara et al. ANNALS OF SURGICAL ONCOLOGY
- Metastasis and chemoresistance in CD133 expressing pancreatic cancer cells are dependent on their lipid raft integrity
- (2018) Vineet Kumar Gupta et al. CANCER LETTERS
- A Paradigm Shift in Cancer Immunotherapy: From Enhancement to Normalization
- (2018) Miguel F. Sanmamed et al. CELL
- An Inhibitor of GSK3B and HDACs Kills Pancreatic Cancer Cells and Slows Pancreatic Tumor Growth and Metastasis in Mice
- (2018) Mouad Edderkaoui et al. GASTROENTEROLOGY
- LAT2 regulates glutamine-dependent mTOR activation to promote glycolysis and chemoresistance in pancreatic cancer
- (2018) Mengyu Feng et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- FOLFIRINOX or Gemcitabine as Adjuvant Therapy for Pancreatic Cancer
- (2018) Thierry Conroy et al. NEW ENGLAND JOURNAL OF MEDICINE
- Systemic treatment of pancreatic cancer revisited
- (2018) Michel Ducreux et al. SEMINARS IN ONCOLOGY
- Oncogenic KRAS supports pancreatic cancer through regulation of nucleotide synthesis
- (2018) Naiara Santana-Codina et al. Nature Communications
- Stereotactic radiotherapy of pancreatic cancer: a systematic review on pain relief
- (2018) Milly Buwenge et al. Journal of Pain Research
- Pancreatic stellate cell activation is regulated by fatty acids and ER stress
- (2017) Yael Ben-Harosh et al. EXPERIMENTAL CELL RESEARCH
- Resection of pancreatic cancer in Europe and USA: an international large-scale study highlighting large variations
- (2017) Lei Huang et al. GUT
- Fibroblast drug scavenging increases intratumoural gemcitabine accumulation in murine pancreas cancer
- (2017) E Hessmann et al. GUT
- Targeting metabolic reprogramming in KRAS-driven cancers
- (2017) Kenji Kawada et al. International Journal of Clinical Oncology
- Up-regulation of glycolysis promotes the stemness and EMT phenotypes in gemcitabine-resistant pancreatic cancer cells
- (2017) Hengqiang Zhao et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Gambogic acid sensitizes gemcitabine efficacy in pancreatic cancer by reducing the expression of ribonucleotide reductase subunit-M2 (RRM2)
- (2017) Guanggai Xia et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Safety and tolerability of the first-in-class agent CPI-613 in combination with modified FOLFIRINOX in patients with metastatic pancreatic cancer: a single-centre, open-label, dose-escalation, phase 1 trial
- (2017) Angela Alistar et al. LANCET ONCOLOGY
- Paraoxonase 2 Facilitates Pancreatic Cancer Growth and Metastasis by Stimulating GLUT1-Mediated Glucose Transport
- (2017) Arvindhan Nagarajan et al. MOLECULAR CELL
- mTOR Inhibition Restores Amino Acid Balance in Cells Dependent on Catabolism of Extracellular Protein
- (2017) Michel Nofal et al. MOLECULAR CELL
- Glucose feeds the TCA cycle via circulating lactate
- (2017) Sheng Hui et al. NATURE
- Epigenomic reprogramming during pancreatic cancer progression links anabolic glucose metabolism to distant metastasis
- (2017) Oliver G McDonald et al. NATURE GENETICS
- Connexin-43 channels are a pathway for discharging lactate from glycolytic pancreatic ductal adenocarcinoma cells
- (2017) T H Dovmark et al. ONCOGENE
- Stromal cues regulate the pancreatic cancer epigenome and metabolome
- (2017) Mara H. Sherman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Consuming a Ketogenic Diet while Receiving Radiation and Chemotherapy for Locally Advanced Lung Cancer and Pancreatic Cancer: The University of Iowa Experience of Two Phase 1 Clinical Trials
- (2017) Amir Zahra et al. RADIATION RESEARCH
- The Role of Radiation Therapy for Pancreatic Cancer in the Adjuvant and Neoadjuvant Settings
- (2017) Shahed N. Badiyan et al. Surgical Oncology Clinics of North America
- Metabolic Interactions in the Tumor Microenvironment
- (2017) Costas A. Lyssiotis et al. TRENDS IN CELL BIOLOGY
- Nano albumin bound-paclitaxel in pancreatic cancer: Current evidences and future directions
- (2017) Guido Giordano et al. WORLD JOURNAL OF GASTROENTEROLOGY
- Glycolysis regulates the expansion of myeloid-derived suppressor cells in tumor-bearing hosts through prevention of ROS-mediated apoptosis
- (2017) Shiou-Ling Jian et al. Cell Death & Disease
- Collagen-derived proline promotes pancreatic ductal adenocarcinoma cell survival under nutrient limited conditions
- (2017) Orianne Olivares et al. Nature Communications
- Critical role for arginase 2 in obesity-associated pancreatic cancer
- (2017) Tamara Zaytouni et al. Nature Communications
- Compensatory metabolic networks in pancreatic cancers upon perturbation of glutamine metabolism
- (2017) Douglas E. Biancur et al. Nature Communications
- Galectin-3, a Druggable Vulnerability for KRAS-Addicted Cancers
- (2017) Laetitia Seguin et al. Cancer Discovery
- Disrupting glutamine metabolic pathways to sensitize gemcitabine-resistant pancreatic cancer
- (2017) Ru Chen et al. Scientific Reports
- Macropinocytosis of Nab-paclitaxel Drives Macrophage Activation in Pancreatic Cancer
- (2017) Jane Cullis et al. Cancer Immunology Research
- Lipid Metabolism and Lipid Droplets in Pancreatic Cancer and Stellate Cells
- (2017) Yoshiaki Sunami et al. Cancers
- Pancreatic Cancer Chemoresistance to Gemcitabine
- (2017) Manoj Amrutkar et al. Cancers
- Energy sources identify metabolic phenotypes in pancreatic cancer
- (2016) Chen Liang et al. ACTA BIOCHIMICA ET BIOPHYSICA SINICA
- Amino acid transporter SLC6A14 is a novel and effective drug target for pancreatic cancer
- (2016) V Coothankandaswamy et al. BRITISH JOURNAL OF PHARMACOLOGY
- Cancer statistics in China, 2015
- (2016) Wanqing Chen et al. CA-A CANCER JOURNAL FOR CLINICIANS
- Regulation of the Nampt-mediated NAD salvage pathway and its therapeutic implications in pancreatic cancer
- (2016) Huai-Qiang Ju et al. CANCER LETTERS
- Gemcitabine treatment promotes pancreatic cancer stemness through the Nox/ROS/NF-κB/STAT3 signaling cascade
- (2016) Zhengle Zhang et al. CANCER LETTERS
- Current progress in immunotherapy for pancreatic cancer
- (2016) Kelly Foley et al. CANCER LETTERS
- Oncogenic KRAS Regulates Tumor Cell Signaling via Stromal Reciprocation
- (2016) Christopher J. Tape et al. CELL
- Tumor-Induced IL-6 Reprograms Host Metabolism to Suppress Anti-tumor Immunity
- (2016) Thomas R. Flint et al. Cell Metabolism
- FBW7 (F-box and WD Repeat Domain-Containing 7) Negatively Regulates Glucose Metabolism by Targeting the c-Myc/TXNIP (Thioredoxin-Binding Protein) Axis in Pancreatic Cancer
- (2016) S. Ji et al. CLINICAL CANCER RESEARCH
- Metformin in pancreatic cancer treatment: from clinical trials through basic research to biomarker quantification
- (2016) Archana Bhaw-Luximon et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Influence of Statins and Cholesterol on Mortality Among Patients With Pancreatic Cancer
- (2016) Brian Z. Huang et al. JNCI-Journal of the National Cancer Institute
- Targeting tumour-associated macrophages with CCR2 inhibition in combination with FOLFIRINOX in patients with borderline resectable and locally advanced pancreatic cancer: a single-centre, open-label, dose-finding, non-randomised, phase 1b trial
- (2016) Timothy M Nywening et al. LANCET ONCOLOGY
- FOLFIRINOX for locally advanced pancreatic cancer: a systematic review and patient-level meta-analysis
- (2016) Mustafa Suker et al. LANCET ONCOLOGY
- Arginine Methylation of MDH1 by CARM1 Inhibits Glutamine Metabolism and Suppresses Pancreatic Cancer
- (2016) Yi-Ping Wang et al. MOLECULAR CELL
- Mitochondria-Translocated PGK1 Functions as a Protein Kinase to Coordinate Glycolysis and the TCA Cycle in Tumorigenesis
- (2016) Xinjian Li et al. MOLECULAR CELL
- Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion
- (2016) Cristovão M. Sousa et al. NATURE
- Direct evidence for cancer-cell-autonomous extracellular protein catabolism in pancreatic tumors
- (2016) Shawn M Davidson et al. NATURE MEDICINE
- Cancer metabolism: a therapeutic perspective
- (2016) Ubaldo E. Martinez-Outschoorn et al. Nature Reviews Clinical Oncology
- Abrogating cholesterol esterification suppresses growth and metastasis of pancreatic cancer
- (2016) J Li et al. ONCOGENE
- Monocarboxylate Transporters MCT1 and MCT4 Regulate Migration and Invasion of Pancreatic Ductal Adenocarcinoma Cells
- (2016) Su Chii Kong et al. PANCREAS
- Tissue of origin dictates branched-chain amino acid metabolism in mutant Kras-driven cancers
- (2016) J. R. Mayers et al. SCIENCE
- The Warburg Effect: How Does it Benefit Cancer Cells?
- (2016) Maria V. Liberti et al. TRENDS IN BIOCHEMICAL SCIENCES
- Obesity-Induced Inflammation and Desmoplasia Promote Pancreatic Cancer Progression and Resistance to Chemotherapy
- (2016) J. Incio et al. Cancer Discovery
- Molecular targeted therapy for pancreatic adenocarcinoma: A review of completed and ongoing late phase clinical trials
- (2016) Catalina Mosquera et al. Cancer Genetics
- Tumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolism
- (2016) Hongyun Zhao et al. eLife
- Influence of Statins and Cholesterol on Mortality Among Patients With Pancreatic Cancer
- (2016) Brian Z. Huang et al. JNCI-Journal of the National Cancer Institute
- Warburg metabolism in tumor-conditioned macrophages promotes metastasis in human pancreatic ductal adenocarcinoma
- (2016) Hweixian Leong Penny et al. OncoImmunology
- Hypoxic repression of pyruvate dehydrogenase activity is necessary for metabolic reprogramming and growth of model tumours
- (2016) Tereza Golias et al. Scientific Reports
- The MUC1 oncomucin regulates pancreatic cancer cell biological properties and chemoresistance. Implication of p42–44 MAPK, Akt, Bcl-2 and MMP13 pathways
- (2015) Solange Tréhoux et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Addition of radiotherapy to adjuvant chemotherapy is associated with improved overall survival in resected pancreatic adenocarcinoma: An analysis of the National Cancer Data Base
- (2015) Charles E. Rutter et al. CANCER
- Phase II study of capecitabine and the oral mTOR inhibitor everolimus in patients with advanced pancreatic cancer
- (2015) S. Kordes et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Four types of fatty acids exert differential impact on pancreatic cancer growth
- (2015) Ming Yu et al. CANCER LETTERS
- Therapeutic Targeting of the Warburg Effect in Pancreatic Cancer Relies on an Absence of p53 Function
- (2015) N. V. Rajeshkumar et al. CANCER RESEARCH
- Human Pancreatic Cancer Tumors Are Nutrient Poor and Tumor Cells Actively Scavenge Extracellular Protein
- (2015) J. J. Kamphorst et al. CANCER RESEARCH
- The Utilization of Extracellular Proteins as Nutrients Is Suppressed by mTORC1
- (2015) Wilhelm Palm et al. CELL
- Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression
- (2015) Chih-Hao Chang et al. CELL
- MYC/PGC-1α Balance Determines the Metabolic Phenotype and Plasticity of Pancreatic Cancer Stem Cells
- (2015) Patricia Sancho et al. Cell Metabolism
- Pyruvate kinase isoenzyme M2 is a therapeutic target of gemcitabine-resistant pancreatic cancer cells
- (2015) Dong Joon Kim et al. EXPERIMENTAL CELL RESEARCH
- Tumor mechanics and metabolic dysfunction
- (2015) Jason C. Tung et al. FREE RADICAL BIOLOGY AND MEDICINE
- Stromal biology and therapy in pancreatic cancer: a changing paradigm
- (2015) Albrecht Neesse et al. GUT
- Aromatase inhibitors versus tamoxifen in early breast cancer: patient-level meta-analysis of the randomised trials
- (2015) LANCET
- Targeting pancreatic cancer using a combination of gemcitabine with the omega-3 polyunsaturated fatty acid emulsion, Lipidem™
- (2015) Jonathan Haqq et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Transcriptional control of autophagy–lysosome function drives pancreatic cancer metabolism
- (2015) Rushika M. Perera et al. NATURE
- Asparagine Synthetase Expression and Phase I Study With L-Asparaginase Encapsulated in Red Blood Cells in Patients With Pancreatic Adenocarcinoma
- (2015) Jean-Baptiste Bachet et al. PANCREAS
- Cholesterol uptake disruption, in association with chemotherapy, is a promising combined metabolic therapy for pancreatic adenocarcinoma
- (2015) Fabienne Guillaumond et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Metabolite profiling stratifies pancreatic ductal adenocarcinomas into subtypes with distinct sensitivities to metabolic inhibitors
- (2015) Anneleen Daemen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inhibition of Fatty Acid Oxidation Modulates Immunosuppressive Functions of Myeloid-Derived Suppressor Cells and Enhances Cancer Therapies
- (2015) F. Hossain et al. Cancer Immunology Research
- Salmonella-Based Therapy Targeting Indoleamine 2,3-Dioxygenase Coupled with Enzymatic Depletion of Tumor Hyaluronan Induces Complete Regression of Aggressive Pancreatic Tumors
- (2015) E. R. Manuel et al. Cancer Immunology Research
- Unbiased analysis of pancreatic cancer radiation resistance reveals cholesterol biosynthesis as a novel target for radiosensitisation
- (2014) J J Souchek et al. BRITISH JOURNAL OF CANCER
- Knockdown or inhibition of aldo-keto reductase 1B10 inhibits pancreatic carcinoma growth via modulating Kras–E-cadherin pathway
- (2014) Wanying Zhang et al. CANCER LETTERS
- Repurposing of Metformin and Aspirin by Targeting AMPK-mTOR and Inflammation for Pancreatic Cancer Prevention and Treatment
- (2014) W. Yue et al. Cancer Prevention Research
- Cell Surface Lactate Receptor GPR81 Is Crucial for Cancer Cell Survival
- (2014) C. L. Roland et al. CANCER RESEARCH
- Projecting Cancer Incidence and Deaths to 2030: The Unexpected Burden of Thyroid, Liver, and Pancreas Cancers in the United States
- (2014) L. Rahib et al. CANCER RESEARCH
- Targeting the Warburg effect with a novel glucose transporter inhibitor to overcome gemcitabine resistance in pancreatic cancer cells
- (2014) I-Lu Lai et al. CARCINOGENESIS
- Metabolic Control of Autophagy
- (2014) Lorenzo Galluzzi et al. CELL
- Vitamin D Receptor-Mediated Stromal Reprogramming Suppresses Pancreatitis and Enhances Pancreatic Cancer Therapy
- (2014) Mara H. Sherman et al. CELL
- FOXM1 Promotes the Warburg Effect and Pancreatic Cancer Progression via Transactivation of LDHA Expression
- (2014) J. Cui et al. CLINICAL CANCER RESEARCH
- Autophagy is needed for the growth of pancreatic adenocarcinoma and has a cytoprotective effect against anticancer drugs
- (2014) Daisuke Hashimoto et al. EUROPEAN JOURNAL OF CANCER
- Baseline Metabolic Tumor Volume and Total Lesion Glycolysis Are Associated With Survival Outcomes in Patients With Locally Advanced Pancreatic Cancer Receiving Stereotactic Body Radiation Therapy
- (2014) Avani S. Dholakia et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Functional polarization of tumour-associated macrophages by tumour-derived lactic acid
- (2014) Oscar R. Colegio et al. NATURE
- Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages
- (2014) Stanley Ching-Cheng Huang et al. NATURE IMMUNOLOGY
- Elevation of circulating branched-chain amino acids is an early event in human pancreatic adenocarcinoma development
- (2014) Jared R Mayers et al. NATURE MEDICINE
- Mass Spectrometry-Based Metabolic Profiling of Gemcitabine-Sensitive and Gemcitabine-Resistant Pancreatic Cancer Cells
- (2014) Yoshinori Fujimura et al. PANCREAS
- KRAS: feeding pancreatic cancer proliferation
- (2014) Kirsten L. Bryant et al. TRENDS IN BIOCHEMICAL SCIENCES
- Role of abnormal lipid metabolism in development, progression, diagnosis and therapy of pancreatic cancer
- (2014) Julian Swierczynski WORLD JOURNAL OF GASTROENTEROLOGY
- Autophagy Is Critical for Pancreatic Tumor Growth and Progression in Tumors with p53 Alterations
- (2014) A. Yang et al. Cancer Discovery
- Immune cell infiltration as an indicator of the immune microenvironment of pancreatic cancer
- (2013) Y Ino et al. BRITISH JOURNAL OF CANCER
- Lysine-5 Acetylation Negatively Regulates Lactate Dehydrogenase A and Is Decreased in Pancreatic Cancer
- (2013) Di Zhao et al. CANCER CELL
- Randomized double-blinded, placebo-controlled phase II trial of simvastatin and gemcitabine in advanced pancreatic cancer patients
- (2013) Jung Yong Hong et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis
- (2013) Chih-Hao Chang et al. CELL
- Integration of Metabolomics and Transcriptomics Revealed a Fatty Acid Network Exerting Growth Inhibitory Effects in Human Pancreatic Cancer
- (2013) G. Zhang et al. CLINICAL CANCER RESEARCH
- nab-Paclitaxel mechanisms of action and delivery
- (2013) Denise A. Yardley JOURNAL OF CONTROLLED RELEASE
- Tumor-Derived Lactate Modifies Antitumor Immune Response: Effect on Myeloid-Derived Suppressor Cells and NK Cells
- (2013) Z. Husain et al. JOURNAL OF IMMUNOLOGY
- Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells
- (2013) Cosimo Commisso et al. NATURE
- p53 status determines the role of autophagy in pancreatic tumour development
- (2013) Mathias T. Rosenfeldt et al. NATURE
- Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway
- (2013) Jaekyoung Son et al. NATURE
- Hypoxic and Ras-transformed cells support growth by scavenging unsaturated fatty acids from lysophospholipids
- (2013) J. J. Kamphorst et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Strengthened glycolysis under hypoxia supports tumor symbiosis and hexosamine biosynthesis in pancreatic adenocarcinoma
- (2013) F. Guillaumond et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Tumour-associated mutant p53 drives the Warburg effect
- (2013) Cen Zhang et al. Nature Communications
- Prognostic significance of L-type amino-acid transporter 1 expression in surgically resected pancreatic cancer
- (2012) K Kaira et al. BRITISH JOURNAL OF CANCER
- A phase I dose-escalation trial of 2-deoxy-d-glucose alone or combined with docetaxel in patients with advanced solid tumors
- (2012) Luis E. Raez et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Oncogenic Kras Maintains Pancreatic Tumors through Regulation of Anabolic Glucose Metabolism
- (2012) Haoqiang Ying et al. CELL
- The Metabolic Profile of Tumors Depends on Both the Responsible Genetic Lesion and Tissue Type
- (2012) Mariia O. Yuneva et al. Cell Metabolism
- Overexpression and oncogenic function of aldo-keto reductase family 1B10 (AKR1B10) in pancreatic carcinoma
- (2012) Yeon Tae Chung et al. MODERN PATHOLOGY
- Pancreatic Tumor Sensitivity to Plasma L-Asparagine Starvation
- (2012) Emmanuelle Dufour et al. PANCREAS
- Differential Expression of Metabolic Genes in Tumor and Stromal Components of Primary and Metastatic Loci in Pancreatic Adenocarcinoma
- (2012) Nina V. Chaika et al. PLoS One
- Causes, consequences, and remedies for growth-induced solid stress in murine and human tumors
- (2012) T. Stylianopoulos et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- MUC1 mucin stabilizes and activates hypoxia-inducible factor 1 alpha to regulate metabolism in pancreatic cancer
- (2012) N. V. Chaika et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Reduction in circulating pro‐angiogenic and pro‐inflammatory factors is related to improved outcomes in patients with advanced pancreatic cancer treated with gemcitabine and intravenous omega‐3 fish oil
- (2012) Ali Arshad et al. HPB
- nab -Paclitaxel Potentiates Gemcitabine Activity by Reducing Cytidine Deaminase Levels in a Mouse Model of Pancreatic Cancer
- (2012) Kristopher K. Frese et al. Cancer Discovery
- Harnessing gemcitabine metabolism: a step towards personalized medicine for pancreatic cancer
- (2012) Muhammad Wasif Saif et al. Therapeutic Advances in Medical Oncology
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- The reverse Warburg effect: Aerobic glycolysis in cancer associated fibroblasts and the tumor stroma
- (2011) Stephanos Pavlides et al. CELL CYCLE
- Pancreatic cancers require autophagy for tumor growth
- (2011) S. Yang et al. GENES & DEVELOPMENT
- Indoleamine-2,3-dioxygenase, an immunosuppressive enzyme that inhibits natural killer cell function, as a useful target for ovarian cancer therapy
- (2011) DONGDONG WANG et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Gemcitabine Alone Versus Gemcitabine Plus Radiotherapy in Patients With Locally Advanced Pancreatic Cancer: An Eastern Cooperative Oncology Group Trial
- (2011) Patrick J. Loehrer et al. JOURNAL OF CLINICAL ONCOLOGY
- Cutting Edge: Distinct Glycolytic and Lipid Oxidative Metabolic Programs Are Essential for Effector and Regulatory CD4+ T Cell Subsets
- (2011) R. D. Michalek et al. JOURNAL OF IMMUNOLOGY
- Non-redox-active lipoate derivates disrupt cancer cell mitochondrial metabolism and are potent anticancer agents in vivo
- (2011) Zuzana Zachar et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Glutamine: pleiotropic roles in tumor growth and stress resistance
- (2011) Naval P. Shanware et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- FOLFIRINOX versus Gemcitabine for Metastatic Pancreatic Cancer
- (2011) Thierry Conroy et al. NEW ENGLAND JOURNAL OF MEDICINE
- The role of the Atg1/ULK1 complex in autophagy regulation
- (2010) Noboru Mizushima CURRENT OPINION IN CELL BIOLOGY
- Regulation of the mTOR Complex 1 Pathway by Nutrients, Growth Factors, and Stress
- (2010) Shomit Sengupta et al. MOLECULAR CELL
- Glutamine addiction: a new therapeutic target in cancer
- (2010) David R. Wise et al. TRENDS IN BIOCHEMICAL SCIENCES
- Regulation Mechanisms and Signaling Pathways of Autophagy
- (2009) Congcong He et al. Annual Review of Genetics
- CD147 silencing inhibits lactate transport and reduces malignant potential of pancreatic cancer cells in in vivo and in vitro models
- (2009) W Schneiderhan et al. GUT
- Glucose Deprivation Contributes to the Development of KRAS Pathway Mutations in Tumor Cells
- (2009) J. Yun et al. SCIENCE
- Immunosurveillance of pancreatic adenocarcinoma: Insights from genetically engineered mouse models of cancer
- (2008) Carolyn E. Clark et al. CANCER LETTERS
- Gemcitabine Resistance in Pancreatic Cancer: Picking the Key Players
- (2008) M. P. Kim et al. CLINICAL CANCER RESEARCH
- Glucose deprivation inhibits multiple key gene expression events and effector functions in CD8+ T cells
- (2008) Candace M. Cham et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Oral mTOR Inhibitor Everolimus in Patients With Gemcitabine-Refractory Metastatic Pancreatic Cancer
- (2008) Brian M. Wolpin et al. JOURNAL OF CLINICAL ONCOLOGY
- Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses
- (2008) S. Jones et al. SCIENCE
- 2-Deoxy-d-glucose causes cytotoxicity, oxidative stress, and radiosensitization in pancreatic cancer
- (2007) Mitchell C. Coleman et al. FREE RADICAL BIOLOGY AND MEDICINE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search