Abrogating cholesterol esterification suppresses growth and metastasis of pancreatic cancer

Avasimibe Encapsulated in Human Serum Albumin Blocks Cholesterol Esterification for Selective Cancer Treatment

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Blocking Lipid Synthesis Overcomes Tumor Regrowth and Metastasis after Antiangiogenic Therapy Withdrawal

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Cholesteryl Ester Accumulation Induced by PTEN Loss and PI3K/AKT Activation Underlies Human Prostate Cancer Aggressiveness

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Combining Hedgehog Signaling Inhibition with Focal Irradiation on Reduction of Pancreatic Cancer Metastasis

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Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway

(2013) Jaekyoung Son et al.   NATURE

Cavin-1 is essential for the tumor-promoting effect of caveolin-1 and enhances its prognostic potency in pancreatic cancer

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How does cancer cell metabolism affect tumor migration and invasion?

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Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate

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Tumor Metastasis: Molecular Insights and Evolving Paradigms

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Cholesterol esters as growth regulators of lymphocytic leukaemia cells

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Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth

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Acyl-coenzyme A: Cholesterol acyltransferase inhibitor Avasimibe affect survival and proliferation of glioma tumor cell lines

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Low Cholesterol Triggers Membrane Microdomain-dependent CD44 Shedding and Suppresses Tumor Cell Migration

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Metabolomic Characterization of Human Prostate Cancer Bone Metastases Reveals Increased Levels of Cholesterol

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High ACAT1 expression in estrogen receptor negative basal-like breast cancer cells is associated with LDL-induced proliferation

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Monoacylglycerol Lipase Regulates a Fatty Acid Network that Promotes Cancer Pathogenesis

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Caveolin-1 overexpression correlates with tumour progression markers in pancreatic ductal adenocarcinoma

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Statins Are Not Associated With a Reduced Risk of Pancreatic Cancer at the Population Level, When Taken at Low Doses for Managing Hypercholesterolemia: Evidence From a Meta-Analysis of 12 Studies

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Combined expression of caveolin-1 and an activated AKT/mTOR pathway predicts reduced disease-free survival in clinically confined renal cell carcinoma

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SREBP Activity Is Regulated by mTORC1 and Contributes to Akt-Dependent Cell Growth

(2008) Thomas Porstmann et al.   Cell Metabolism

Metastasis: a therapeutic target for cancer

(2008) Patricia S Steeg et al.   Nature clinical practice. Oncology