Design, Synthesis, and Biological Evaluation of Two Series of Novel A-Ring Fused Steroidal Pyrazines as Potential Anticancer Agents
出版年份 2020 全文链接
标题
Design, Synthesis, and Biological Evaluation of Two Series of Novel A-Ring Fused Steroidal Pyrazines as Potential Anticancer Agents
作者
关键词
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出版物
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 21, Issue 5, Pages 1665
出版商
MDPI AG
发表日期
2020-03-03
DOI
10.3390/ijms21051665
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- (2019) Alejandro Corona-Díaz et al. STEROIDS
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- (2019) Anita Kiss et al. STEROIDS
- Heterocyclic steroids: Efficient routes for annulation of pentacyclic steroidal pyrimidines
- (2019) M. Monier et al. STEROIDS
- Induction of apoptosis and cell cycle arrest by ethyl acetate fraction of Phoenix dactylifera L. (Ajwa dates) in prostate cancer cells
- (2018) Muqtadir Baig Mirza et al. JOURNAL OF ETHNOPHARMACOLOGY
- Synthesis and Evaluation of Manganese(II)-Based Ethylenediaminetetraacetic Acid–Ethoxybenzyl Conjugate as a Highly Stable Hepatobiliary Magnetic Resonance Imaging Contrast Agent
- (2018) Md. Kamrul Islam et al. BIOCONJUGATE CHEMISTRY
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- (2018) Hongling Gu et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Synthesis, cytotoxic evaluation, and molecular docking studies of the semi-synthetic “triterpenoid-steroid” hybrids
- (2018) Irina A. Tolmacheva et al. STEROIDS
- Design, synthesis and antitumor activity of steroidal pyridine derivatives based on molecular docking
- (2018) Ya-Ling Song et al. STEROIDS
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- (2017) Jian Li et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Design, synthesis and biological evaluation of novel androst-3,5-diene-3-carboxylic acid derivatives as inhibitors of 5α-reductase type 1 and 2
- (2017) Kejing Lao et al. STEROIDS
- Investigation of pH and substituent effects on the distribution ratio of novel steroidal ring D- and A-fused arylpyrazole regioisomers and evaluation of their cell-growth inhibitory effects in vitro
- (2017) Ádám Baji et al. STEROIDS
- Novel 3,4- seco bile acid diamides as selective anticancer proliferation and migration agents
- (2016) Shi-Wei Mao et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
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- (2016) Jian Li et al. STEROIDS
- Microwave-assisted one-pot synthesis of steroid–quinoline hybrids and an evaluation of their antiproliferative activities on gynecological cancer cell lines
- (2016) Ádám Baji et al. RSC Advances
- Synthesis and anticancer cell potential of steroidal 16,17-seco-16,17a-dinitriles: Identification of a selective inhibitor of hormone-independent breast cancer cells
- (2015) Andrea R. Nikolić et al. BIOORGANIC & MEDICINAL CHEMISTRY
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- (2015) Bernard Barlaam et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Synthesis and biological evaluation of pharbinilic acid and derivatives as NF-κB pathway inhibitors
- (2015) J. R. Annand et al. CHEMICAL COMMUNICATIONS
- The Cephalostatins. 24. Isolation, Structure, and Cancer Cell Growth Inhibition of Cephalostatin 20
- (2015) George R. Pettit et al. JOURNAL OF NATURAL PRODUCTS
- Therapeutic Potential of Steroidal Alkaloids in Cancer and Other Diseases
- (2015) Qi-Wei Jiang et al. MEDICINAL RESEARCH REVIEWS
- Tryptophan Hydroxylase 1 (Tph-1)-Targeted Bone Anabolic Agents for Osteoporosis
- (2014) Hai-Jian Fu et al. JOURNAL OF MEDICINAL CHEMISTRY
- Design, synthesis and biological evaluation of novel steroidal spiro-oxindoles as potent antiproliferative agents
- (2014) Bin Yu et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Synthesis of E- and Z-isomeric progesterone 3-O-methyloximes
- (2014) V. A. Zolottsev et al. RUSSIAN CHEMICAL BULLETIN
- Multicomponent synthesis of 4,4-dimethyl sterol analogues and their effect on eukaryotic cells
- (2014) Fernando Alonso et al. STEROIDS
- Heterocyclic ring extension of androstenedione: Synthesis and cytotoxicity of fused pyran, pyrimidine and thiazole derivatives
- (2014) Rafat M. Mohareb et al. STEROIDS
- Heterocyclic ring extension of estrone: Synthesis and cytotoxicity of fused pyran, pyrimidine and thiazole derivatives
- (2014) Rafat M. Mohareb et al. STEROIDS
- Autophagy contributes to the survival of CD133+ liver cancer stem cells in the hypoxic and nutrient-deprived tumor microenvironment
- (2013) Yu-jiao Song et al. CANCER LETTERS
- A novel [1,2,4] triazolo [1,5-a] pyrimidine-based phenyl-linked steroid dimer: Synthesis and its cytotoxic activity
- (2013) Bin Yu et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- The Knoevenagel reactions of pregnenolone with cyanomethylene reagents: Synthesis of thiophene, thieno[2,3-b]pyridine, thieno[3,2-d]isoxazole derivatives of pregnenolone and their in vitro cytotoxicity towards tumor and normal cell lines
- (2013) Rafat M. Mohareb et al. STEROIDS
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- (2013) Biao Ma et al. STEROIDS
- Ursane-type pentacyclic triterpenoids as useful platforms to discover anticancer drugs
- (2012) Jorge A. R. Salvador et al. NATURAL PRODUCT REPORTS
- Anticancer steroids: linking natural and semi-synthetic compounds
- (2012) Jorge A. R. Salvador et al. NATURAL PRODUCT REPORTS
- Reaction of pregnenolone with cyanoacetylhydrazine: Novel synthesis of hydrazide–hydrazone, pyrazole, pyridine, thiazole, thiophene derivatives and their cytotoxicity evaluations
- (2012) Rafat M. Mohareb et al. STEROIDS
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- (2012) Rafat M. Mohareb et al. STEROIDS
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- (2012) Mustapha Haddach et al. ACS Medicinal Chemistry Letters
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- (2010) Abid H. Banday et al. STEROIDS
- Studies on novel D-ring substituted steroidal pyrazolines as potential anticancer agents
- (2010) Abid H. Banday et al. STEROIDS
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