Synthesis of novel, DNA binding heterocyclic dehydroabietylamine derivatives as potential antiproliferative and apoptosis-inducing agents

Trifluoromethyl aryl sulfonates (TFMS): An applicable trifluoromethoxylation reagent

(2019) Meng Lei et al.   TETRAHEDRON LETTERS

Preparation and biological evaluation of soluble tetrapeptide epoxyketone proteasome inhibitors

(2019) Meng Lei et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Design, synthesis, molecular docking of new lipophilic acetamide derivatives affording potential anticancer and antimicrobial agents

(2018) Hany E.A. Ahmed et al.   BIOORGANIC CHEMISTRY

Synthesis and Antitumor Activity of 1-Phenyl-4-substituted Phthalazine Derivatives

(2018) Jingchao Xin et al.   CHINESE JOURNAL OF ORGANIC CHEMISTRY

High anticancer potency on tumor cells of dehydroabietylamine Schiff-base derivatives and a copper(II) complex

(2018) Fengyi Zhao et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

One-pot palladium-catalyzed synthesis of functionalized 10 H -pyrido[1,2- a ]quinoxalin-10-ones under copper-free conditions

(2018) Atena Soozani et al.   TETRAHEDRON

Co-delivery nanoparticles of doxorubicin and chloroquine for improving the anti-cancer effect in vitro

(2018) Jia-Hui Sun et al.   NANOTECHNOLOGY

Hypocrellin A-based photodynamic action induces apoptosis in A549 cells through ROS-mediated mitochondrial signaling pathway

(2018) Shanshan Qi et al.   Acta Pharmaceutica Sinica B

Synthesis and biological evaluation of novel chalcone derivatives as a new class of microtubule destabilizing agents

(2017) Xiaochao Huang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Novel Fully Biobased Benzoxazines from Rosin: Synthesis and Properties

(2017) Xiaoyun Liu et al.   ACS Sustainable Chemistry & Engineering

Synthesis of novel diterpenoid analogs with in-vivo antitumor activity

(2016) Ying-Ying Wang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Sulfonamide chalcones: Synthesis and in vitro exploration for therapeutic potential against Brugia malayi

(2016) Sandeep P. Bahekar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and antileishmanial activity of C7- and C12-functionalized dehydroabietylamine derivatives

(2016) M. Auxiliadora Dea-Ayuela et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, synthesis, cytotoxicities and DNA cleavage activities of dibenzoxepine and isoquinoline derivatives starting from dehydroabietylamine

(2016) Chao-Xiang Liu et al.   JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

Enantiopure copper(II) complex of natural product rosin derivative: DNA binding, DNA cleavage and cytotoxicity

(2016) Bao-Li Fei et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

(+)-Dehydroabietylamine derivatives target triple-negative breast cancer

(2015) Taotao Ling et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

High loading of doxorubicin into styrene-terminated porous silicon nanoparticles via π-stacking for cancer treatments in vitro

(2015) Bing Xia et al.   RSC Advances

Antitumor Activity and Structure-Activity Relationship of Diterpenoids with a Dehydroabietyl Skeleton

(2014) Xiaoping Rao et al.   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

Synthesis and Biological Evaluation of New Quinoxaline Derivatives of ICF01012 as Melanoma-Targeting Probes

(2014) Radhia El Aissi et al.   ACS Medicinal Chemistry Letters

Natural product based leads to fight against leishmaniasis

(2013) Nisha Singh et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Sulphonamido-quinoxalines: Search for anticancer agent

(2013) Rahul Ingle et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Reaction of pregnenolone with cyanoacetylhydrazine: Novel synthesis of hydrazide–hydrazone, pyrazole, pyridine, thiazole, thiophene derivatives and their cytotoxicity evaluations

(2012) Rafat M. Mohareb et al.   STEROIDS

Synthesis of D-ring-substituted (5′R)- and (5′S)-17β-pyrazolinylandrostene epimers and comparison of their potential anticancer activities

(2012) Zoltán Iványi et al.   STEROIDS

Synthesis and antimycobacterial properties of N-substituted 6-amino-5-cyanopyrazine-2-carboxamides

(2011) Jan Zitko et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Synthesis of novel D-ring fused 7′-aryl-androstano[17,16-d][1,2,4] triazolo[1,5-a]pyrimidines

(2011) Li-Hua Huang et al.   STEROIDS

Novel thiophene derivatives as PTP1B inhibitors with selectivity and cellular activity

(2010) Deju Ye et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Identification of 2,3,6-trisubstituted quinoxaline derivatives as a Wnt2/β-catenin pathway inhibitor in non-small-cell lung cancer cell lines

(2010) Sang-Bum Lee et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Hairpin-shaped tetranuclear palladium(II) complex: Synthesis, crystal structure, DNA binding and cytotoxicity activity studies

(2010) En-Jun Gao et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Fused aromatic thienopyrazines: structure, properties and function

(2010) Rajib Mondal et al.   JOURNAL OF MATERIALS CHEMISTRY

Intensely blue-fluorescent 2,5-bis(benzoimidazol-2-yl)pyrazine dyes with improved solubility: their synthesis, fluorescent properties, and application as microenvironment polarity probes

(2010) Ryota Saito et al.   TETRAHEDRON

A new class of anticonvulsants possessing 6Hz activity: 3,4-Dialkyloxy thiophene bishydrazones

(2009) Ravi Kulandasamy et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

QSAR analysis for quinoxaline-2-carboxylate 1,4-di-N-oxides as anti-mycobacterial agents

(2009) Esther Vicente et al.   JOURNAL OF MOLECULAR GRAPHICS & MODELLING

Cytochrome P450 Oxidation of the Thiophene-Containing Anticancer Drug 3-[(Quinolin-4-ylmethyl)-amino]-thiophene-2-carboxylic Acid (4-Trifluoromethoxy-phenyl)-amide to an Electrophilic Intermediate

(2008) Christine Medower et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Synthesis and characterization of dinuclear macrocyclic cobalt(II), copper(II) and zinc(II) complexes derived from 2,2,2′,2′-S,S[bis(bis-N,N-2-thiobenzimidazolyloxalato-1,2-ethane)]: DNA binding and cleavage studies

(2008) Farukh Arjmand et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Fragment Based Design of New H4Receptor−Ligands with Anti-inflammatory Properties in Vivo

(2008) Rogier A. Smits et al.   JOURNAL OF MEDICINAL CHEMISTRY

Androgenic profile and genotoxicity evaluation of testosterone propionate and novel synthesized heterocyclic steroids

(2008) Hanaa Y. Hana et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY