期刊
TETRAHEDRON
卷 74, 期 1, 页码 150-156出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2017.11.055
关键词
Palladium-catalyzed reaction; Sonogashira coupling reaction; Copper-free; Pyrido[1,2-a]quinoxaline
资金
- Research Council of the Shahrood University of Technology
Reactions of 3-substituted-2-chloroquinoxalines, terminal alkynes, and 1,3-dicarbonyl compounds in the presence of palladium catalyst afforded a number of 6,8,9-trisubstituted-10H-pyrido[1,2-a]quinoxalin10-ones in 60-86% reaction yields. This one-pot protocol provided an efficient, practical, and direct method for the synthesis of pyrido[1,2-alquinoxalines from readily available starting materials in the absence of a copper salt. (C) 2017 Elsevier Ltd. All rights reserved.
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