标题
Apelin/APJ system: an emerging therapeutic target for respiratory diseases
作者
关键词
-
出版物
CELLULAR AND MOLECULAR LIFE SCIENCES
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2020-03-04
DOI
10.1007/s00018-020-03461-7
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Obstructive sleep apnea treatment, slow wave activity, and amyloid-β
- (2019) Yo-El S. Ju et al. ANNALS OF NEUROLOGY
- Bmpr2 Mutant Rats Develop Pulmonary and Cardiac Characteristics of Pulmonary Arterial Hypertension
- (2019) Aurélie Hautefort et al. CIRCULATION
- Cardioprotective apelin effects and the cardiac-renal axis: review of existing science and potential therapeutic applications of synthetic and native regulated apelin
- (2019) Carina Ureche et al. JOURNAL OF HUMAN HYPERTENSION
- Hypoxia exposure alleviates impaired muscular metabolism, glucose tolerance, and aerobic capacity in apelin-knockout mice
- (2019) Shiyi He et al. FEBS Open Bio
- Warburg effect is involved in apelin-13-induced human aortic vascular smooth muscle cells proliferation
- (2019) Qionglin Zhou et al. JOURNAL OF CELLULAR PHYSIOLOGY
- ELABELA, as a potential diagnostic biomarker of pre-eclampsia, regulates abnormally shallow placentation via APJ
- (2019) Lu Zhou et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Ferritinophagy activation and sideroflexin1-dependent mitochondria iron overload is involved in apelin-13-induced cardiomyocytes hypertrophy
- (2019) Mingzhu Tang et al. FREE RADICAL BIOLOGY AND MEDICINE
- Mechanism of KLF4 Protection against Acute Liver Injury via Inhibition of Apelin Signaling
- (2019) Weitao Ji et al. Oxidative Medicine and Cellular Longevity
- Wnt/β-catenin pathway promotes acute lung injury induced by LPS through driving the Th17 response in mice
- (2018) Li Cheng et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Adipokine apelin ameliorates chronic colitis in Il-10−/− mice by promoting intestinal lymphatic functions
- (2018) Yuanyuan Ge et al. BIOCHEMICAL PHARMACOLOGY
- Review: Apelin in disease
- (2018) Hanna Antushevich et al. CLINICA CHIMICA ACTA
- Serum concentrations of apelin-17 isoform vary in accordance to blood pressure categories in individuals with obesity class 3
- (2018) Luis Javier Cano Martínez et al. CLINICAL AND EXPERIMENTAL HYPERTENSION
- Apelin-13 deficiency alters cortical bone geometry, organic bone matrix, and inhibits Wnt/β-catenin signaling
- (2018) Xiao-fang Han et al. GENERAL AND COMPARATIVE ENDOCRINOLOGY
- Acute inhalation of ozone induces DNA methylation of apelin in lungs of Long-Evans rats
- (2018) Colette N. Miller et al. INHALATION TOXICOLOGY
- Apelin Reduces Nitric Oxide–Induced Relaxation of Cerebral Arteries by Inhibiting Activation of Large-Conductance, Calcium-Activated K Channels
- (2018) Amreen Mughal et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- ROS-Autophagy pathway mediates monocytes-human umbilical vein endothelial cells adhesion induced by apelin-13
- (2018) Meiqing Liu et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Humanin prevents high glucose-induced monocyte adhesion to endothelial cells by targeting KLF2
- (2018) Xiaohui Wang et al. MOLECULAR IMMUNOLOGY
- Apelin, a promising target for Alzheimer disease prevention and treatment
- (2018) Javad Masoumi et al. NEUROPEPTIDES
- The hypotensive effect of activated apelin receptor is correlated with β-arrestin recruitment
- (2018) Élie Besserer-Offroy et al. PHARMACOLOGICAL RESEARCH
- Apelin in Reproductive Physiology and Pathology of Different Species: A Critical Review
- (2018) Patrycja Kurowska et al. International Journal of Endocrinology
- Inhibitory regulation of skin fibrosis in systemic sclerosis by apelin/APJ signaling
- (2018) Yoko Yokoyama et al. Arthritis & Rheumatology
- Hypoxia-Induced Pulmonary Hypertension in Different Mouse Strains - Relation to Transcriptome
- (2018) Kahori T Ikeda et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Association of Brain Natriuretic Peptide Gene Polymorphisms with Chronic Obstructive Pulmonary Disease Complicated with Pulmonary Hypertension and Its Mechanism
- (2018) Guangjun Jin et al. BIOSCIENCE REPORTS
- Apelin-13 Administration Protects Against LPS-Induced Acute Lung Injury by Inhibiting NF-κB Pathway and NLRP3 Inflammasome Activation
- (2018) Hailin Zhang et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Pulmonary Vascular Platform Models the Effects of Flow and Pressure on Endothelial Dysfunction in BMPR2 Associated Pulmonary Arterial Hypertension
- (2018) Reid D’Amico et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Endothelial AMP-Activated Kinase α1 Phosphorylates eNOS on Thr495 and Decreases Endothelial NO Formation
- (2018) Nina Zippel et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Targeting drugs to APJ receptor: From signaling to pathophysiological effects
- (2018) Zhen Huang et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Piezo1 and Gq/G11 promote endothelial inflammation depending on flow pattern and integrin activation
- (2018) Julián Albarrán-Juárez et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The exerkine apelin reverses age-associated sarcopenia
- (2018) Claire Vinel et al. NATURE MEDICINE
- MicroRNA-150 relieves vascular remodeling and fibrosis in hypoxia-induced pulmonary hypertension
- (2018) Ying Li et al. BIOMEDICINE & PHARMACOTHERAPY
- Apelin/APJ system: A novel promising target for anti-aging intervention
- (2018) Qionglin Zhou et al. CLINICA CHIMICA ACTA
- PINK1/Parkin-mediated mitophagy promotes apelin-13-induced vascular smooth muscle cell proliferation by AMPKα and exacerbates atherosclerotic lesions
- (2018) Lu He et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Apelin/APJ system: A potential therapeutic target for endothelial dysfunction-related diseases
- (2018) Jun Cheng et al. JOURNAL OF CELLULAR PHYSIOLOGY
- miR‑371b‑5p inhibits endothelial cell apoptosis in monocrotaline‑induced pulmonary arterial hypertension via PTEN/PI3K/Akt signaling pathways
- (2018) Guangfa Zhu et al. Molecular Medicine Reports
- Inflammatory cytokines tumor necrosis factor‑α, interleukin‑8 and sleep monitoring in patients with obstructive sleep apnea syndrome
- (2018) Hao Ming et al. Experimental and Therapeutic Medicine
- Apj+ Vessels Drive Tumor Growth and Represent a Tractable Therapeutic Target
- (2018) Huan Zhao et al. Cell Reports
- Apelin/APJ system: A bifunctional target for cardiac hypertrophy
- (2017) Liqun Lu et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Apelin/APJ system: A novel potential therapy target for kidney disease
- (2017) Zhen Huang et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Organotypic vasculature: From descriptive heterogeneity to functional pathophysiology
- (2017) Hellmut G. Augustin et al. SCIENCE
- Efficacy of continuous positive airway pressure treatment in treating obstructive sleep apnea hypopnea syndrome associated with carotid arteriosclerosis
- (2017) Yong‑Qian Jiang et al. Experimental and Therapeutic Medicine
- Endoplasmic reticulum stress: a novel mechanism and therapeutic target for cardiovascular diseases
- (2016) Mei-qing Liu et al. ACTA PHARMACOLOGICA SINICA
- Serum Apelin 13 Levels in Patients With Pulmonary Embolism
- (2016) Hadice Selimoglu Şen et al. CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS
- PAK1-cofilin phosphorylation mediates human lung adenocarcinoma cells migration induced by apelin-13
- (2016) Deguan Lv et al. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
- Proteins associated with EGFR-TKIs resistance in patients with non-small cell lung cancer revealed by mass spectrometry
- (2016) Shaoyu Yang et al. Molecular Medicine Reports
- The role of apelin in the assessment of response to chemotherapyand prognosis in stage 4 nonsmall cell lung cancer
- (2016) Sinem ERMİN et al. Turkish Journal Of Medical Sciences
- Using Multi-objective Optimization to Identify Dynamical Network Biomarkers as Early-warning Signals of Complex Diseases
- (2016) Fatemeh Vafaee Scientific Reports
- Apelin-13 promotes cardiomyocyte hypertrophy via PI3K-Akt-ERK1/2-p70S6K and PI3K-induced autophagy
- (2015) Feng Xie et al. ACTA BIOCHIMICA ET BIOPHYSICA SINICA
- Platelet-derived Wnt antagonist Dickkopf-1 is implicated in ICAM-1/VCAM-1-mediated neutrophilic acute lung inflammation
- (2015) Y. Guo et al. BLOOD
- The Apelin-APJ Axis Is an Endogenous Counterinjury Mechanism in Experimental Acute Lung Injury
- (2015) Xiao-Fang Fan et al. CHEST
- Is there an association between obstructive sleep apnea syndrome and periodontal inflammation?
- (2015) N. Nizam et al. Clinical Oral Investigations
- The Emerging Potential of the Apelin-APJ System in Heart Failure
- (2015) Jonathan R. Dalzell et al. JOURNAL OF CARDIAC FAILURE
- Genetic differences and aberrant methylation in the apelin system predict the risk of high-altitude pulmonary edema
- (2015) Aastha Mishra et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- ELABELA: a novel hormone in cardiac development acting as a new endogenous ligand for the APJ receptor
- (2014) Feng Xie et al. ACTA BIOCHIMICA ET BIOPHYSICA SINICA
- Better off Blue:BMPR-2Mutation, Arteriovenous Malformation, and Pulmonary Arterial Hypertension
- (2014) Elaine Soon et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Dynamics of apelin receptor/G protein coupling in living cells
- (2014) Bo Bai et al. EXPERIMENTAL CELL RESEARCH
- Apelin inhibits the proliferation and migration of rat PASMCsviathe activation of PI3K/Akt/mTOR signal and the inhibition of autophagy under hypoxia
- (2014) Hongyu Zhang et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Systems-level regulation of microRNA networks by miR-130/301 promotes pulmonary hypertension
- (2014) Thomas Bertero et al. JOURNAL OF CLINICAL INVESTIGATION
- Structure–Activity Relationship Studies toward the Discovery of Selective Apelin Receptor Agonists
- (2014) Jean-François Margathe et al. JOURNAL OF MEDICINAL CHEMISTRY
- Toddler: An Embryonic Signal That Promotes Cell Movement via Apelin Receptors
- (2014) A. Pauli et al. SCIENCE
- ERK1/2 mediates lung adenocarcinoma cell proliferation and autophagy induced by apelin-13
- (2013) L. Yang et al. ACTA BIOCHIMICA ET BIOPHYSICA SINICA
- The apelin receptor APJ: journey from an orphan to a multifaceted regulator of homeostasis
- (2013) Anne-Marie O'Carroll et al. JOURNAL OF ENDOCRINOLOGY
- Leptin, Obestatin and Apelin levels in patients with obstructive sleep apnoea syndrome
- (2013) Sabine Zirlik et al. MEDICAL SCIENCE MONITOR
- Decreased apelin and apelin-receptor expression in the pulmonary vasculature of nitrofen-induced congenital diaphragmatic hernia
- (2013) Alejandro D. Hofmann et al. PEDIATRIC SURGERY INTERNATIONAL
- Apelin/APJ Signaling Is a Critical Regulator of Statin Effects in Vascular Endothelial Cells—Brief Report
- (2012) Danielle L. McLean et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Expression of Angiotensin II Receptor-like 1 in the Placentas of Pregnancy-induced Hypertension
- (2012) Mitsuko Furuya et al. INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY
- Pak1/LIMK1/Cofilin Pathway Contributes to Tumor Migration and Invasion in Human Non-Small Cell Lung Carcinomas and Cell Lines
- (2012) Inseok Jang et al. KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY
- APJ acts as a dual receptor in cardiac hypertrophy
- (2012) Maria Cecilia Scimia et al. NATURE
- An endothelial apelin-FGF link mediated by miR-424 and miR-503 is disrupted in pulmonary arterial hypertension
- (2012) Jongmin Kim et al. NATURE MEDICINE
- Apelin receptor expression in ischemic and non- ischemic kidneys and cardiovascular responses to apelin in chronic two‐kidney–one‐clip hypertension in rats
- (2012) Hamid Najafipour et al. REGULATORY PEPTIDES
- Serum apelin-12 level is elevated in schoolchildren with atopic asthma
- (2012) Edyta Machura et al. RESPIRATORY MEDICINE
- Serum leptin and adiponectin levels correlate with exercise-induced bronchoconstriction in children with asthma
- (2011) Hey-Sung Baek et al. ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY
- Disruption of the Apelin-APJ System Worsens Hypoxia-Induced Pulmonary Hypertension
- (2011) Suparna M. Chandra et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Disruption of PPARγ/β-catenin–mediated regulation of apelin impairs BMP-induced mouse and human pulmonary arterial EC survival
- (2011) Tero-Pekka Alastalo et al. JOURNAL OF CLINICAL INVESTIGATION
- Emerging Role of Apelin as a Therapeutic Target in Cancer: A Patent Review
- (2011) Srujana Rayalam et al. Recent Patents on Anti-Cancer Drug Discovery
- Apelin and Pulmonary Hypertension
- (2011) Charlotte U. Andersen et al. Pulmonary Circulation
- Apelin Expression in Human Non-small Cell Lung Cancer: Role in Angiogenesis and Prognosis
- (2010) Judit Berta et al. Journal of Thoracic Oncology
- Hemodynamic effect of apelin in a canine model of acute pulmonary thromboembolism
- (2010) Jing-hui Feng et al. PEPTIDES
- Flow Activation of AMP-Activated Protein Kinase in Vascular Endothelium Leads to Krüppel-Like Factor 2 Expression
- (2009) Angela Young et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- G Protein-Coupled Receptor APJ and Its Ligand Apelin Act Downstream of Cripto to Specify Embryonic Stem Cells Toward the Cardiac Lineage Through Extracellular Signal-Regulated Kinase/p70S6 Kinase Signaling Pathway
- (2009) Cristina D'Aniello et al. CIRCULATION RESEARCH
- Identification and pharmacological properties of E339-3D6, the first nonpeptidic apelin receptor agonist
- (2009) Xavier Iturrioz et al. FASEB JOURNAL
- [Pyr 1 ]Apelin-13 Identified as the Predominant Apelin Isoform in the Human Heart
- (2009) Janet J. Maguire et al. HYPERTENSION
- Plasma apelin levels in obstructive sleep apnea and the effect of continuous positive airway pressure therapy
- (2009) David E Henley et al. JOURNAL OF ENDOCRINOLOGY
- Pulmonary apelin levels and effects in rats with hypoxic pulmonary hypertension
- (2009) C.U. Andersen et al. RESPIRATORY MEDICINE
- Apelin-13 induces ERK1/2 but not p38 MAPK activation through coupling of the human apelin receptor to the Gi2pathway
- (2008) Bo Bai et al. ACTA BIOCHIMICA ET BIOPHYSICA SINICA
- In vivo genetic profiling and cellular localization of apelin reveals a hypoxia-sensitive, endothelial-centered pathway activated in ischemic heart failure
- (2007) Ahmad Y. Sheikh et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
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