Systems-level regulation of microRNA networks by miR-130/301 promotes pulmonary hypertension

Walking the interactome to identify human miRNA-disease associations through the functional link between miRNA targets and disease genes

(2013) Hongbo Shi et al.   BMC Systems Biology

MicroRNA-Antagonism Regulates Breast Cancer Stemness and Metastasis via TET-Family-Dependent Chromatin Remodeling

(2013) Su Jung Song et al.   CELL

Role for DNA Damage Signaling in Pulmonary Arterial Hypertension

(2013) Jolyane Meloche et al.   CIRCULATION

Regulation of Cardiac MicroRNAs by Cardiac MicroRNAs

(2013) Scot J. Matkovich et al.   CIRCULATION RESEARCH

The Role of miRNAs in Regulating Gene Expression Networks

(2013) Allan M. Gurtan et al.   JOURNAL OF MOLECULAR BIOLOGY

Genetics and Genomics of Pulmonary Arterial Hypertension

(2013) Florent Soubrier et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

MiR-221 and miR-130a Regulate Lung Airway and Vascular Development

(2013) Sana Mujahid et al.   PLoS One

Circulating miRNAs as Potential Marker for Pulmonary Hypertension

(2013) Chuanyu Wei et al.   PLoS One

Signal Transduction in the Development of Pulmonary Arterial Hypertension

(2013) Simon Malenfant et al.   Pulmonary Circulation

miRNA-130a Targets ATG2B and DICER1 to Inhibit Autophagy and Trigger Killing of Chronic Lymphocytic Leukemia Cells

(2012) V. Kovaleva et al.   CANCER RESEARCH

Sequential Application of Anticancer Drugs Enhances Cell Death by Rewiring Apoptotic Signaling Networks

(2012) Michael J. Lee et al.   CELL

MicroRNA-21 Integrates Pathogenic Signaling to Control Pulmonary Hypertension

(2012) Victoria N. Parikh et al.   CIRCULATION

The Emerging Paradigm of Network Medicine in the Study of Human Disease

(2012) Stephen Y. Chan et al.   CIRCULATION RESEARCH

Peroxisome Proliferator-Activated Receptor-γ Ameliorates Pulmonary Arterial Hypertension by Inhibiting 5-Hydroxytryptamine 2B Receptor

(2012) Yahan Liu et al.   HYPERTENSION

An endothelial apelin-FGF link mediated by miR-424 and miR-503 is disrupted in pulmonary arterial hypertension

(2012) Jongmin Kim et al.   NATURE MEDICINE

Holding our breath: The emerging and anticipated roles of microRNA in pulmonary hypertension

(2012) Kevin White et al.   Pulmonary Circulation

MicroRNA-130a Mediates Proliferation of Vascular Smooth Muscle Cells in Hypertension

(2011) W.-H. Wu et al.   AMERICAN JOURNAL OF HYPERTENSION

Dehydroepiandrosterone inhibits the Src/STAT3 constitutive activation in pulmonary arterial hypertension

(2011) Roxane Paulin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The PPARγ ligand rosiglitazone attenuates hypoxia-induced endothelin signaling in vitro and in vivo

(2011) Bum-Yong Kang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

A Novel Murine Model of Severe Pulmonary Arterial Hypertension

(2011) Loredana Ciuclan et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

MicroRNA-130a-mediated down-regulation of Smad4 contributes to reduced sensitivity to TGF- 1 stimulation in granulocytic precursors

(2011) M. Hager et al.   BLOOD

Signal Transducers and Activators of Transcription-3/Pim1 Axis Plays a Critical Role in the Pathogenesis of Human Pulmonary Arterial Hypertension

(2011) Roxane Paulin et al.   CIRCULATION

Disruption of PPARγ/β-catenin–mediated regulation of apelin impairs BMP-induced mouse and human pulmonary arterial EC survival

(2011) Tero-Pekka Alastalo et al.   JOURNAL OF CLINICAL INVESTIGATION

Role for miR-204 in human pulmonary arterial hypertension

(2011) Audrey Courboulin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Silencing of microRNA families by seed-targeting tiny LNAs

(2011) Susanna Obad et al.   NATURE GENETICS

Schistosomiasis-Induced Experimental Pulmonary Hypertension

(2010) Brian B. Graham et al.   AMERICAN JOURNAL OF PATHOLOGY

Upregulation of Oct-4 isoforms in pulmonary artery smooth muscle cells from patients with pulmonary arterial hypertension

(2010) Amy L. Firth et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

miR-301a as an NF-κB activator in pancreatic cancer cells

(2010) Zhongxin Lu et al.   EMBO JOURNAL

Heme oxygenase-1/p21WAF1 mediates peroxisome proliferator-activated receptor-γ signaling inhibition of proliferation of rat pulmonary artery smooth muscle cells

(2010) Manxiang Li et al.   FEBS Journal

The von Hippel–Lindau Chuvash mutation promotes pulmonary hypertension and fibrosis in mice

(2010) Michele M. Hickey et al.   JOURNAL OF CLINICAL INVESTIGATION

miR-130 Suppresses Adipogenesis by Inhibiting Peroxisome Proliferator-Activated Receptor   Expression

(2010) E. K. Lee et al.   MOLECULAR AND CELLULAR BIOLOGY

Network medicine: a network-based approach to human disease

(2010) Albert-László Barabási et al.   NATURE REVIEWS GENETICS

Rosiglitazone Attenuates Chronic Hypoxia–Induced Pulmonary Hypertension in a Mouse Model

(2009) Rachel E. Nisbet et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

PPAR  Activation: A Potential Treatment For Pulmonary Hypertension

(2009) G. Hansmann et al.   Science Translational Medicine

Interleukin-6 Overexpression Induces Pulmonary Hypertension

(2008) M. Kathryn Steiner et al.   CIRCULATION RESEARCH

Most mammalian mRNAs are conserved targets of microRNAs

(2008) R. C. Friedman et al.   GENOME RESEARCH

An antiproliferative BMP-2/PPARγ/apoE axis in human and murine SMCs and its role in pulmonary hypertension

(2008) Georg Hansmann et al.   JOURNAL OF CLINICAL INVESTIGATION

Pathogenic mechanisms of pulmonary arterial hypertension

(2007) Stephen Y. Chan et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY