Apelin/APJ system: A potential therapeutic target for endothelial dysfunction-related diseases
出版年份 2018 全文链接
标题
Apelin/APJ system: A potential therapeutic target for endothelial dysfunction-related diseases
作者
关键词
-
出版物
JOURNAL OF CELLULAR PHYSIOLOGY
Volume -, Issue -, Pages -
出版商
Wiley
发表日期
2018-12-26
DOI
10.1002/jcp.27942
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Apelin impairs myogenic response to induce diabetic nephropathy in mice
- (2018) Jia Zhang et al. FASEB JOURNAL
- The apelin receptor influences biomechanical and morphological properties of endothelial cells
- (2018) Anne Strohbach et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Apelin/APJ system: A critical regulator of vascular smooth muscle cell
- (2018) Xuling Luo et al. JOURNAL OF CELLULAR PHYSIOLOGY
- ROS-Autophagy pathway mediates monocytes-human umbilical vein endothelial cells adhesion induced by apelin-13
- (2018) Meiqing Liu et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Association of polymorphisms of leptin, leptin receptor and apelin receptor genes with susceptibility to coronary artery disease and hypertension
- (2018) Zohreh Nowzari et al. LIFE SCIENCES
- An Expedient Synthesis of CMF-019: (S)-5-Methyl-3-{1-(pentan-3-yl)-2-(thiophen-2-ylmethyl)-1H-benzo[d]imidazole-5-carboxamido}hexanoic acid, a Potent Apelin Receptor (APJ) Agonist
- (2018) Lena Trifonov et al. Medicinal Chemistry
- MiR-503 suppresses hypoxia-induced proliferation, migration and angiogenesis of endothelial progenitor cells by targeting Apelin
- (2018) Ya Wen et al. PEPTIDES
- The hypotensive effect of activated apelin receptor is correlated with β-arrestin recruitment
- (2018) Élie Besserer-Offroy et al. PHARMACOLOGICAL RESEARCH
- Targeting drugs to APJ receptor: From signaling to pathophysiological effects
- (2018) Zhen Huang et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Erythro-myeloid progenitors contribute endothelial cells to blood vessels
- (2018) Alice Plein et al. NATURE
- Apelin promotes mesenchymal stem cells survival and vascularization under hypoxic-ischemic condition in vitro involving the upregulation of vascular endothelial growth factor
- (2017) Jingying Hou et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- Protamine is an antagonist of apelin receptor, and its activity is reversed by heparin
- (2017) Sophie Le Gonidec et al. FASEB JOURNAL
- The differential effects of low and high doses of apelin through opioid receptors on the blood pressure of rats with renovascular hypertension
- (2017) Mahboobeh Yeganeh-Hajahmadi et al. HYPERTENSION RESEARCH
- Apelin involved in progression of diabetic nephropathy by inhibiting autophagy in podocytes
- (2017) Yu Liu et al. Cell Death & Disease
- Apln-CreERT:mT/mG reporter mice as a tool for sprouting angiogenesis study
- (2017) Jingjiang Pi et al. BMC Ophthalmology
- Apelin protects against myocardial ischemic injury by inhibiting dynamin-related protein 1
- (2017) Wei Xu et al. Oncotarget
- An apelin receptor antagonist prevents pathological retinal angiogenesis with ischemic retinopathy in mice
- (2017) Yuki Ishimaru et al. Scientific Reports
- Apelin receptor signaling: a novel mechanism of endothelial cell polarization
- (2016) Hong Zhao et al. ACTA BIOCHIMICA ET BIOPHYSICA SINICA
- Amelioration of acute myocardial infarction by saponins from flower buds of Panax notoginseng via pro-angiogenesis and anti-apoptosis
- (2016) Bin-Rui Yang et al. JOURNAL OF ETHNOPHARMACOLOGY
- Apelinergic system in endothelial cells and its role in angiogenesis in myocardial ischemia
- (2016) Vera Novakova et al. VASCULAR PHARMACOLOGY
- In vivo modulation of endothelial polarization by Apelin receptor signalling
- (2016) Hyouk-Bum Kwon et al. Nature Communications
- Suppression of endothelial CD39/ENTPD1 is associated with pulmonary vascular remodeling in pulmonary arterial hypertension
- (2015) Mikko H. Helenius et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Characterization of apela, a novel endogenous ligand of apelin receptor, in the adult heart
- (2015) Ábel Perjés et al. BASIC RESEARCH IN CARDIOLOGY
- Apelin-13 impedes foam cell formation by activating Class III PI3K/Beclin-1-mediated autophagic pathway
- (2015) Feng Yao et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Regulation of the endothelial apelin/APJ system by hemodynamic fluid flow
- (2015) Raila Busch et al. CELLULAR SIGNALLING
- Post-infarct treatment with [Pyr1]apelin-13 improves myocardial function by increasing neovascularization and overexpression of angiogenic growth factors in rats
- (2015) Yaser Azizi et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Apelin receptors: From signaling to antidiabetic strategy
- (2015) C. Chaves-Almagro et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Design, Characterization, and First-In-Human Study of the Vascular Actions of a Novel Biased Apelin Receptor Agonist
- (2015) A. L. Brame et al. HYPERTENSION
- Apelin promotes diabetic nephropathy by inducing podocyte dysfunction via inhibiting proteasome activities
- (2015) Caixia Guo et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Investigation of changes in apelin receptor mRNA and protein expression in the myocardium and aorta of rats with two-kidney, one-clip (2K1C) Goldblatt hypertension
- (2015) Hamid Najafipour et al. JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY
- Serum apelin is associated with left ventricular hypertrophy in untreated hypertension patients
- (2015) Lijun Ye et al. Journal of Translational Medicine
- Hypoxia induces the proliferation of endothelial progenitor cells via upregulation of Apelin/APLNR/MAPK signaling
- (2015) JINGCHANG ZHANG et al. Molecular Medicine Reports
- Apelin/APJ signaling promotes hypoxia-induced proliferation of endothelial progenitor cells via Phosphoinositide-3 kinase/Akt signaling
- (2015) JINGCHANG ZHANG et al. Molecular Medicine Reports
- Apelin Protects Primary Rat Retinal Pericytes from Chemical Hypoxia-Induced Apoptosis
- (2015) Li Chen et al. Journal of Ophthalmology
- The hormonal peptide Elabela guides angioblasts to the midline during vasculogenesis
- (2015) Christian SM Helker et al. eLife
- TIMP3 interplays with apelin to regulate cardiovascular metabolism in hypercholesterolemic mice
- (2015) Robert Stöhr et al. Molecular Metabolism
- Apelin promotes lymphangiogenesis and lymph node metastasis
- (2015) Judit Berta et al. Oncotarget
- Elabela-Apelin Receptor Signaling Pathway is Functional in Mammalian Systems
- (2015) Zhi Wang et al. Scientific Reports
- Apelin-13 and APJ in paraventricular nucleus contribute to hypertension via sympathetic activation and vasopressin release in spontaneously hypertensive rats
- (2014) F. Zhang et al. Acta Physiologica
- Activation of the Endothelin System Mediates Pathological Angiogenesis during Ischemic Retinopathy
- (2014) Chintan Patel et al. AMERICAN JOURNAL OF PATHOLOGY
- Adiponectin/T-cadherin and apelin/APJ expression in human arteries and periadventitial fat: implication of local adipokine signaling in atherosclerosis?
- (2014) Christos G. Kostopoulos et al. CARDIOVASCULAR PATHOLOGY
- Apelin
- (2014) Ying Zhou et al. International Heart Journal
- Sirt3 is essential for apelin-induced angiogenesis in post-myocardial infarction of diabetes
- (2014) Xuwei Hou et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Systems-level regulation of microRNA networks by miR-130/301 promotes pulmonary hypertension
- (2014) Thomas Bertero et al. JOURNAL OF CLINICAL INVESTIGATION
- Apelin-13 stimulates angiogenesis by promoting cross-talk between AMP-activated protein kinase and Akt signaling in myocardial microvascular endothelial cells
- (2014) XIAOMAN YANG et al. Molecular Medicine Reports
- Teaching NeuroImages: Primary Sjogren syndrome presenting as isolated lesion of medulla oblongata
- (2014) J. Chen et al. NEUROLOGY
- Therapeutic angiogenesis for critical limb ischemia
- (2014) Sae Hee Ko et al. Seminars in Vascular Surgery
- Apelin gene therapy increases myocardial vascular density and ameliorates diabetic cardiomyopathy via upregulation of sirtuin 3
- (2013) Heng Zeng et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Inhibition of apelin expression switches endothelial cells from proliferative to mature state in pathological retinal angiogenesis
- (2013) Atsushi Kasai et al. ANGIOGENESIS
- Apelin Effects on Blood Pressure and RAS in DOCA-Salt-Induced Hypertensive Rats
- (2013) Raziye Akcılar et al. CLINICAL AND EXPERIMENTAL HYPERTENSION
- ELABELA: A Hormone Essential for Heart Development Signals via the Apelin Receptor
- (2013) Serene C. Chng et al. DEVELOPMENTAL CELL
- Masked Hypertension and Atherogenesis: The Impact of Apelin and Relaxin Plasma Levels
- (2013) Dimitris P. Papadopoulos et al. Journal of Clinical Hypertension
- Apelin inhibits the development of diabetic nephropathy by regulating histone acetylation in Akita mouse
- (2013) Hong Chen et al. JOURNAL OF PHYSIOLOGY-LONDON
- Regulation of feeding behavior, gastrointestinal function and fluid homeostasis by apelin
- (2013) Shuang-Yu Lv et al. PEPTIDES
- Post-infarct treatment with [Pyr1]-apelin-13 reduces myocardial damage through reduction of oxidative injury and nitric oxide enhancement in the rat model of myocardial infarction
- (2013) Yaser Azizi et al. PEPTIDES
- Promoting Effects of the Adipokine, Apelin, on Diabetic Nephropathy
- (2013) Bao-hai Zhang et al. PLoS One
- Myocardial Injection of Apelin-Overexpressing Bone Marrow Cells Improves Cardiac Repair via Upregulation of Sirt3 after Myocardial Infarction
- (2013) Lanfang Li et al. PLoS One
- Loss of Apelin Exacerbates Myocardial Infarction Adverse Remodeling and Ischemia‐reperfusion Injury: Therapeutic Potential of Synthetic Apelin Analogues
- (2013) Wang Wang et al. Journal of the American Heart Association
- Inhibition of apelin expression by BMP signaling in endothelial cells
- (2012) Odette Poirier et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Apelin-13 increases myocardial progenitor cells and improves repair postmyocardial infarction
- (2012) Lanfang Li et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Apelin–APJ induces ICAM-1, VCAM-1 and MCP-1 expression via NF-κB/JNK signal pathway in human umbilical vein endothelial cells
- (2012) Ying Lu et al. AMINO ACIDS
- Apelin-13 increases expression of ATP-binding cassette transporter A1 via activating protein kinase C α signaling in THP-1 macrophage-derived foam cells
- (2012) Xiao-Yan Liu et al. ATHEROSCLEROSIS
- Discovery of 4-oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 4-nitrobenzoate (ML221) as a functional antagonist of the apelin (APJ) receptor
- (2012) Patrick R. Maloney et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- PDGFRβ triggered by bFGF promotes the proliferation and migration of endothelial progenitor cells via p-ERK signalling
- (2012) Sufen Guo et al. CELL BIOLOGY INTERNATIONAL
- Adipokines: a novel link between adiposity and carotid plaque vulnerability
- (2012) Nikolaos P. E. Kadoglou et al. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
- An endothelial apelin-FGF link mediated by miR-424 and miR-503 is disrupted in pulmonary arterial hypertension
- (2012) Jongmin Kim et al. NATURE MEDICINE
- Interactive Association of Five Candidate Polymorphisms in Apelin/APJ Pathway with Coronary Artery Disease among Chinese Hypertensive Patients
- (2012) Wei Jin et al. PLoS One
- In Vivo Reduction of Reperfusion Injury to the Heart with Apelin-12 Peptide in Rats
- (2011) O. I. Pisarenko et al. BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE
- Discovery of a Competitive Apelin Receptor (APJ) Antagonist
- (2011) N. J. Maximilian Macaluso et al. ChemMedChem
- Apelin levels in normal pregnancy
- (2011) Anargyros Kourtis et al. CLINICAL ENDOCRINOLOGY
- Apelin Serum Levels are not Associated with Early Atherosclerosis or Fat Distribution in Young Subjects with Increased Risk for Type 2 Diabetes
- (2011) K. Rittig et al. EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES
- Apelin stimulates glucose uptake through the PI3K/Akt pathway and improves insulin resistance in 3T3-L1 adipocytes
- (2011) Shunming Zhu et al. MOLECULAR AND CELLULAR BIOCHEMISTRY
- 14-3-3 mediates apelin-13-induced enhancement of adhesion of monocytes to human umbilical vein endothelial cells
- (2010) X. Li et al. ACTA BIOCHIMICA ET BIOPHYSICA SINICA
- Apelin Attenuates Hyperoxic Lung and Heart Injury in Neonatal Rats
- (2010) Yvonne P. de Visser et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Apelin Is a Crucial Factor for Hypoxia-Induced Retinal Angiogenesis
- (2010) Atsushi Kasai et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Identification and functional analysis of endothelial tip cell-enriched genes
- (2010) R. del Toro et al. BLOOD
- Apelin Expression in Human Non-small Cell Lung Cancer: Role in Angiogenesis and Prognosis
- (2010) Judit Berta et al. Journal of Thoracic Oncology
- Apelin is a novel islet peptide
- (2010) Camilla Ringström et al. REGULATORY PEPTIDES
- Apelin Gene Transfer Into the Rostral Ventrolateral Medulla Induces Chronic Blood Pressure Elevation in Normotensive Rats
- (2009) Qi Zhang et al. CIRCULATION RESEARCH
- Plasma apelin concentration is depressed following acute myocardial infarction in man
- (2009) Robin A.P. Weir et al. EUROPEAN JOURNAL OF HEART FAILURE
- Identification and pharmacological properties of E339-3D6, the first nonpeptidic apelin receptor agonist
- (2009) Xavier Iturrioz et al. FASEB JOURNAL
- Family-based analysis of apelin and AGTRL1 gene polymorphisms with hypertension in Han Chinese
- (2009) Wei-Wei Li et al. JOURNAL OF HYPERTENSION
- Effects of rosiglitazone and metformin treatment on apelin, visfatin, and ghrelin levels in patients with type 2 diabetes mellitus
- (2009) Nikolaos P.E. Kadoglou et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Apelin Levels Are Increased in Morbidly Obese Subjects with Type 2 Diabetes Mellitus
- (2009) Federico Soriguer et al. OBESITY SURGERY
- Apelin protects heart against ischemia/reperfusion injury in rat
- (2009) Xiang Jun Zeng et al. PEPTIDES
- Maturation of blood vessels by haematopoietic stem cells and progenitor cells: Involvement of apelin/APJ and angiopoietin/Tie2 interactions in vessel caliber size regulation
- (2009) Nobuyuki Takakura et al. THROMBOSIS AND HAEMOSTASIS
- Vascular endothelial growth factor immobilized in collagen scaffold promotes penetration and proliferation of endothelial cells
- (2008) Yi Hao Shen et al. Acta Biomaterialia
- Retardation of Retinal Vascular Development in Apelin-Deficient Mice
- (2008) Atsushi Kasai et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Apelin Stimulates Glucose Utilization in Normal and Obese Insulin-Resistant Mice
- (2008) Cédric Dray et al. Cell Metabolism
- Hypoxia-Induced Apelin Expression Regulates Endothelial Cell Proliferation and Regenerative Angiogenesis
- (2008) Mélanie Eyries et al. CIRCULATION RESEARCH
- Spatial and temporal role of the apelin/APJ system in the caliber size regulation of blood vessels during angiogenesis
- (2008) Hiroyasu Kidoya et al. EMBO JOURNAL
- Effect of hypocaloric diet-induced weight loss in obese women on plasma apelin and adipose tissue expression of apelin and APJ.
- (2008) Isabelle Castan-Laurell et al. EUROPEAN JOURNAL OF ENDOCRINOLOGY
- Low Plasma Apelin Levels in Newly Diagnosed Type 2 Diabetes Mellitus
- (2008) G. Erdem et al. EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES
- Apelin/APJ signaling system: a potential link between adipose tissue and endothelial angiogenic processes
- (2008) O. Kunduzova et al. FASEB JOURNAL
- Apelin signaling modulates splanchnic angiogenesis and portosystemic collateral vessel formation in rats with portal hypertension
- (2008) Carolina Tiani et al. JOURNAL OF HEPATOLOGY
- Pericyte coverage decreases invasion of tumour cells into blood vessels in prostate cancer xenografts
- (2008) K Welén et al. PROSTATE CANCER AND PROSTATIC DISEASES
- In vivo genetic profiling and cellular localization of apelin reveals a hypoxia-sensitive, endothelial-centered pathway activated in ischemic heart failure
- (2007) Ahmad Y. Sheikh et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More