Apelin inhibits the proliferation and migration of rat PASMCsviathe activation of PI3K/Akt/mTOR signal and the inhibition of autophagy under hypoxia

Chloroquine Prevents Progression of Experimental Pulmonary Hypertension via Inhibition of Autophagy and Lysosomal Bone Morphogenetic Protein Type II Receptor Degradation

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Suppression of Autophagy Enhanced Growth Inhibition and Apoptosis of Interferon-β in Human Glioma Cells

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Regulation and Functional Significance of Autophagy in Respiratory Cell Biology and Disease

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Autophagy is induced through the ROS-TP53-DRAM1 pathway in response to mitochondrial protein synthesis inhibition

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The role of autophagy during coxsackievirus infection of neural progenitor and stem cells

(2012) Jenna M. Tabor-Godwin et al.   Autophagy

Autophagy and cardiovascular aging

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Attenuating Endoplasmic Reticulum Stress as a Novel Therapeutic Strategy in Pulmonary Hypertension

(2012) Peter Dromparis et al.   CIRCULATION

Modulation of glutamine metabolism by the PI(3)K–PKB–FOXO network regulates autophagy

(2012) Kristan E. van der Vos et al.   NATURE CELL BIOLOGY

An endothelial apelin-FGF link mediated by miR-424 and miR-503 is disrupted in pulmonary arterial hypertension

(2012) Jongmin Kim et al.   NATURE MEDICINE

Inhibition of CLIC4 Enhances Autophagy and Triggers Mitochondrial and ER Stress-Induced Apoptosis in Human Glioma U251 Cells under Starvation

(2012) Jiateng Zhong et al.   PLoS One

Caffeine induces apoptosis by enhancement of autophagy via PI3K/Akt/mTOR/p70S6K inhibition

(2011) Shinji Saiki et al.   Autophagy

Hypoxia-inducible factors in human pulmonary arterial hypertension: a link to the intrinsic myeloid abnormalities

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AMPK-mediated autophagy is a survival mechanism in androgen-dependent prostate cancer cells subjected to androgen deprivation and hypoxia

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Pulmonary Artery Smooth Muscle Cell Senescence Is a Pathogenic Mechanism for Pulmonary Hypertension in Chronic Lung Disease

(2011) Hibo Noureddine et al.   CIRCULATION RESEARCH

Characteristics and Outcome After Hospitalization for Acute Right Heart Failure in Patients With Pulmonary Arterial Hypertension

(2011) François Haddad et al.   Circulation-Heart Failure

On the role of autophagy in human diseases: a gender perspective

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mTOR-STAT3-notch signalling contributes to ALDH2-induced protection against cardiac contractile dysfunction and autophagy under alcoholism

(2011) Wei Ge et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Disruption of PPARγ/β-catenin–mediated regulation of apelin impairs BMP-induced mouse and human pulmonary arterial EC survival

(2011) Tero-Pekka Alastalo et al.   JOURNAL OF CLINICAL INVESTIGATION

Apelin stimulates glucose uptake through the PI3K/Akt pathway and improves insulin resistance in 3T3-L1 adipocytes

(2011) Shunming Zhu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Apelin Attenuates the Osteoblastic Differentiation of Vascular Smooth Muscle Cells

(2011) Peng-Fei Shan et al.   PLoS One

Glycogen Synthase Kinase 3beta Contributes to Proliferation of Arterial Smooth Muscle Cells in Pulmonary Hypertension

(2011) Piotr Sklepkiewicz et al.   PLoS One

Apelin and Pulmonary Hypertension

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Autophagosome Formation and Molecular Mechanism of Autophagy

(2010) Isei Tanida   ANTIOXIDANTS & REDOX SIGNALING

Targeting the pro-death and pro-survival functions of autophagy as novel therapeutic strategies in cancer

(2010) Kevin Dalby et al.   Autophagy

New perspectives for the treatment of pulmonary hypertension

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Pulmonary hypertension and pulmonary arterial hypertension: a clarification is needed

(2010) N. Galie et al.   EUROPEAN RESPIRATORY JOURNAL

Autophagy plays a protective role in free cholesterol overload-induced death of smooth muscle cells

(2010) Kedi Xu et al.   JOURNAL OF LIPID RESEARCH

Circulating smooth muscle progenitor cells in arterial remodeling

(2010) Jan-Marcus Daniel et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Autophagy: Snapshot of the network

(2010) Beth Levine et al.   NATURE

Autophagy in mammalian development and differentiation

(2010) Noboru Mizushima et al.   NATURE CELL BIOLOGY

Autophagy gone awry in neurodegenerative diseases

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Factors that prognosticate mortality in idiopathic pulmonary arterial hypertension: A systematic review of the literature

(2010) John Robert Swiston et al.   RESPIRATORY MEDICINE

Autophagy in cigarette smoke-induced chronic obstructive pulmonary disease

(2010) Stefan W Ryter et al.   Expert Review of Respiratory Medicine

Apelin decreases myocardial injury and improves right ventricular function in monocrotaline-induced pulmonary hypertension

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Prognostic factors of acute heart failure in patients with pulmonary arterial hypertension

(2009) B. Sztrymf et al.   EUROPEAN RESPIRATORY JOURNAL

Mechanisms of intermittent hypoxia induced hypertension

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The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5

(2009) Kasper M.A. Rouschop et al.   JOURNAL OF CLINICAL INVESTIGATION

Pulmonary apelin levels and effects in rats with hypoxic pulmonary hypertension

(2009) C.U. Andersen et al.   RESPIRATORY MEDICINE

Apelin Stimulates Glucose Utilization in Normal and Obese Insulin-Resistant Mice

(2008) Cédric Dray et al.   Cell Metabolism

Regulation of cell cycle entry by PTEN in smooth muscle cell proliferation of human coronary artery bypass conduits

(2008) Guanghong Jia et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Egr-1 Regulates Autophagy in Cigarette Smoke-Induced Chronic Obstructive Pulmonary Disease

(2008) Zhi-Hua Chen et al.   PLoS One

In vivo genetic profiling and cellular localization of apelin reveals a hypoxia-sensitive, endothelial-centered pathway activated in ischemic heart failure

(2007) Ahmad Y. Sheikh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY