Catalytic Enantioselective Direct Aldol Addition of Aryl Ketones to α-Fluorinated Ketones

Direct Catalytic Asymmetric Aldol Reaction of α-Alkoxyamides to α-Fluorinated Ketones

(2019) Roman Pluta et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The fluorination of C-H bonds: developments and perspectives

(2019) Veronique Gouverneur et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Modern Approaches for Asymmetric Construction of Carbon–Fluorine Quaternary Stereogenic Centers: Synthetic Challenges and Pharmaceutical Needs

(2018) Yi Zhu et al.   CHEMICAL REVIEWS

Catalytic enantioselective aldol reactions

(2018) Yasuhiro Yamashita et al.   CHEMICAL SOCIETY REVIEWS

Combining prolinamides with 2-pyrrolidinone: Novel organocatalysts for the asymmetric aldol reaction

(2018) Ismini Vlasserou et al.   TETRAHEDRON

Bifunctional iminophosphorane superbases: Potent organocatalysts for enantio- and diastereoselective Michael addition reactions

(2018) Alistair J.M. Farley et al.   TETRAHEDRON

Bifunctional iminophosphorane catalysed enantioselective sulfa-Michael addition of alkyl thiols to alkenyl benzimidazoles

(2018) Michele Formica et al.   Chemical Science

Asymmetric vinylogous aldol addition of alkylidene oxindoles on trifluoromethyl-α,β-unsaturated ketones

(2018) Simone Crotti et al.   RSC Advances

Direct Catalytic Asymmetric Aldol Addition of an α-CF3 Amide to Arylglyoxal Hydrates

(2017) Akinobu Matsuzawa et al.   JOURNAL OF ORGANIC CHEMISTRY

Total Synthesis of (−)-Himalensine A

(2017) Heyao Shi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalytic decarboxylative aldol reaction of β-ketoacids with α-ketophosphonates en route to the enantioselective synthesis of tertiary α-hydroxyphosphonates

(2017) Ganga B. Vamisetti et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Organocatalytic Enantioselective Cross-Aldol Reaction of o-Hydroxyarylketones and Trifluoromethyl Ketones

(2017) Pei Wang et al.   ORGANIC LETTERS

Enantio- and Diastereoselective Organocatalytic Conjugate Additions of Nitroalkanes to Enone Diesters

(2017) Matthew A. Horwitz et al.   ORGANIC LETTERS

Enantioselective Synthesis of anti-β-Hydroxy-α-amino Esters via an Organocatalyzed Decarboxylative Aldol Reaction

(2017) Yoshiji Takemoto et al.   SYNLETT

Enantioselective aldol reactions with masked fluoroacetates

(2016) Jakub Saadi et al.   Nature Chemistry

Tertiary amino thiourea-catalyzed asymmetric cross aldol reaction of aryl methyl ketones with aryl trifluoromethyl ketones

(2016) Léopold Mpaka Lutete et al.   TETRAHEDRON LETTERS

Ni-Catalyzed Highly Chemo-, Regio-, and Enantioselective Decarboxylative Aldol Reaction of β,γ-Unsaturated α-Ketoesters with β-Ketoacids

(2015) Ai-Jia Wei et al.   JOURNAL OF ORGANIC CHEMISTRY

Bifunctional Iminophosphorane Catalyzed Enantioselective Sulfa-Michael Addition to Unactivated α-Substituted Acrylate Esters

(2015) Alistair J. M. Farley et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Organocatalytic Reductive Coupling Reactions between Benzylidene Pyruvates and Aldehydes

(2015) Matthew A. Horwitz et al.   ORGANIC LETTERS

Direct Catalytic Asymmetric Synthesis of β-Hydroxy Acids from Malonic Acid

(2015) Hang Gao et al.   ORGANIC LETTERS

Dependence of Stereoelectronic and Charge Effects on pKaValues of 1,3-Dithiane-Derived Sulfides, Sulfoxides, and Sulfones: An Experimental and Computational Investigation

(2014) Bastian D. Süveges et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Fine-Tuning the Structures of Chiral Diamine Ligands in the Catalytic Asymmetric Aldol Reactions of Trifluoromethyl Aromatic Ketones with Linear Aliphatic Ketones

(2014) Hua Zong et al.   JOURNAL OF ORGANIC CHEMISTRY

Iterative Direct Aldol Strategy for Polypropionates: Enantioselective Total Synthesis of (−)-Membrenone A and B

(2014) Kaliyamoorthy Alagiri et al.   ORGANIC LETTERS

Asymmetric Synthesis of Trisubstituted Oxazolidinones by the Thiourea-Catalyzed Aldol Reaction of 2-Isocyanatomalonate Diester

(2014) Shota Sakamoto et al.   ORGANIC LETTERS

Creation through Immobilization: A New Family of High Performance Heterogeneous Bifunctional Iminophosphorane (BIMP) Superbase Organocatalysts

(2014) Anna M. Goldys et al.   ORGANIC LETTERS

Enantioselective Primary Amine Catalyzed Aldol-Type Construction of Trifluoromethylated Tertiary Alcohols

(2014) Li Li et al.   SYNLETT

Enantioselective aldol reactions of α,β-unsaturated ketones with trifluoroacetophenone catalyzed by a chiral primary amine

(2014) Jing Lin et al.   TETRAHEDRON-ASYMMETRY

Asymmetric Aldol Reaction of Glyoxal Catalyzed by Diarylprolinol

(2013) Yujiro Hayashi et al.   ChemCatChem

Direct Aldol Strategy in Enantioselective Total Synthesis of Thuggacin B

(2013) Akinobu Matsuzawa et al.   CHEMISTRY-A EUROPEAN JOURNAL

Bifunctional Iminophosphorane Organocatalysts for Enantioselective Synthesis: Application to the Ketimine Nitro-Mannich Reaction

(2013) Marta G. Núñez et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Aqueous organocatalyzed aldol reaction of glyoxylic acid for the enantioselective synthesis of α-hydroxy-γ-keto acids

(2013) Fernando J. N. Moles et al.   RSC Advances

Biomimetic catalytic enantioselective decarboxylative aldol reaction of β-ketoacids with trifluoromethyl ketones

(2012) Yan Zheng et al.   CHEMICAL COMMUNICATIONS

Highly Enantioselective Organocatalytic Trifluoromethyl Carbinol Synthesis—A Caveat on Reaction Times and Product Isolation

(2012) Nongnaphat Duangdee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Direct α-Functionalization of Simple Aldehydes via Oxidative N-Heterocyclic Carbene Catalysis

(2012) Junming Mo et al.   ORGANIC LETTERS

Anti-Selective Direct Catalytic Asymmetric Aldol Reaction of Thiolactams

(2012) Devarajulu Sureshkumar et al.   ORGANIC LETTERS

Convenient and efficient decarboxylative aldol reaction of malonic acid half esters with trifluoromethyl ketones

(2012) Xiao-Juan Li et al.   TETRAHEDRON LETTERS

Construction of Tertiary Alcohols Bearing Perfluoroalkyl Chains Catalyzed by Prolinamide-Thioureas

(2011) Christoforos G. Kokotos   JOURNAL OF ORGANIC CHEMISTRY

Efficient Organocatalytic Cross-Aldol Reaction between Aliphatic Aldehydes through Their Functional Differentiation

(2011) Taichi Kano et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly diastereoselective vinylogous Mukaiyama aldol reaction of α-keto phosphonates with 2-(trimethylsilyloxy)furan catalyzed by Cu(OTf)2

(2011) Jipan Yu et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

N-(Heteroarenesulfonyl)prolinamides-Catalyzed Aldol Reaction between Acetone and Aryl Trihalomethyl Ketones

(2011) Noriyuki Hara et al.   ORGANIC LETTERS

Quinidine Thiourea-Catalyzed Aldol Reaction of Unactivated Ketones: Highly Enantioselective Synthesis of 3-Alkyl-3-hydroxyindolin-2-ones

(2010) Qunsheng Guo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The direct catalytic asymmetric aldol reaction

(2010) Barry M. Trost et al.   CHEMICAL SOCIETY REVIEWS

A Graphical Journey of Innovative Organic Architectures That Have Improved Our Lives

(2010) Nicholas A. McGrath et al.   JOURNAL OF CHEMICAL EDUCATION

Fluorine in health care: Organofluorine containing blockbuster drugs

(2010) David O’Hagan   JOURNAL OF FLUORINE CHEMISTRY

Highly Enantioselective and Efficient Organocatalytic Aldol Reaction of Acetone and β,γ-Unsaturated α-Keto Ester

(2010) Pengfei Li et al.   ORGANIC LETTERS

Stereoselective Synthesis of Highly Functionalized Structures from Lactate-Derived Halo Ketones†

(2009) Joaquim Nebot et al.   JOURNAL OF ORGANIC CHEMISTRY

Titanocene-Promoted Intermolecular Couplings of Epoxides with Nitriles. An Easy Access to β-Hydroxyketones

(2009) A. Fernández-Mateos et al.   JOURNAL OF ORGANIC CHEMISTRY

Understanding organofluorine chemistry. An introduction to the C–F bond

(2007) David O'Hagan   CHEMICAL SOCIETY REVIEWS

Fluorine in medicinal chemistry

(2007) Sophie Purser et al.   CHEMICAL SOCIETY REVIEWS