Review
Medicine, Research & Experimental
Zeynab Kohandel, Tahereh Farkhondeh, Michael Aschner, Ali Mohammad Pourbagher-Shahri, Saeed Samarghandian
Summary: This study summarizes the anti-inflammatory efficacy of astaxanthin in various chronic and acute disorders, as well as the pathways through which it mediates its effects. Further experimental and clinical studies are needed to confirm the anti-inflammatory and protective effects of astaxanthin in humans. The review suggests that astaxanthin, with its demonstrated anti-inflammatory properties, may be a suitable candidate for drug design with novel technology.
BIOMEDICINE & PHARMACOTHERAPY
(2022)
Article
Biochemistry & Molecular Biology
Ashley K. Putman, G. Andres Contreras
Summary: Dysregulated inflammation and oxidative stress play significant roles in various diseases. Macrophages are crucial in immune responses and regulate inflammation by exhibiting different phenotypes. IsoPs, as biomarkers of oxidative stress, can promote an anti-inflammatory macrophage phenotype during inflammation, contributing to disease prevention and mitigation.
Article
Food Science & Technology
Danila Cianciosi, Tamara Y. Forbes-Hernandez, Jose M. Alvarez-Suarez, Johura Ansary, Denise Quinzi, Adolfo Amici, Maria D. Navarro-Hortal, Adelaida Esteban-Munoz, Jose Luis Quiles, Maurizio Battino, Francesca Giampieri
Summary: Chestnut and Eucalyptus honeys exhibited significant anti-inflammatory effects on LPS-stressed macrophages, reducing apoptosis, promoting wound healing, regulating antioxidant enzyme activities, and protecting mitochondrial respiration. These honeys modulated the expression of inflammatory biomarkers to decrease inflammation.
JOURNAL OF FUNCTIONAL FOODS
(2021)
Article
Chemistry, Organic
Huiqin Wei, Huijia Chen, Shun Liu, Meixia Tan, Zhiqiang Zhang, Xiuzhi Xu, Fang Ke
Summary: Reactive oxygen species (ROS) are significant species in biological cells and play important roles in cell functions. This study introduces a novel fluorescent probe, MPSPI, which can detect hydrogen peroxide with good selectivity, low cytotoxicity, low detection limit, and quick reaction time. It has been successfully applied in cell imaging.
TETRAHEDRON LETTERS
(2023)
Article
Engineering, Chemical
Thuy Thi Trinh, Ailyn Fadriquela, Johny Bajgai, Subham Sharma, Md. Habibur Rahman, Seong-Hoon Goh, Song-Sik Khang, Woo-Rham Khang, Cheol-Su Kim, Kyu-Jae Lee
Summary: The study demonstrated that weak alkaline reduced water exhibits antioxidant effects by regulating the MAPK signaling pathway to enhance cell viability and reduce levels of oxidative stress markers.
Article
Chemistry, Physical
Yu-Bo Wang, Hui-Zhen Luo, Cheng-Yun Wang, Zhi-Qian Guo, Wei-Hong Zhu
Summary: A novel "turn-on" fluorescent probe BC-OB was constructed in this study by regulating the intramolecular charge transfer process to detect H2O2 with high sensitivity. The probe showed a low detection limit and successfully trapped endogenous H2O2 in cells, indicating its potential as an efficient indicator for imaging H2O2.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
(2021)
Article
Endocrinology & Metabolism
Bilal Sahin, Mustafa Ergul
Summary: Captopril has a protective effect on glial cell damage after H2O2-induced oxidative stress by inhibiting oxidative stress, reducing inflammation, and suppressing apoptosis.
METABOLIC BRAIN DISEASE
(2022)
Article
Food Science & Technology
Thi Hoa My Tran, Sanghyun Lee, Jeong-Eun Huh, Haribalan Perumalsamy, Sri Renukadevi Balusamy, Yeon-Ju Kim
Summary: The study found that Bifidobacterium animalis subsp. lactis fermented Moringa oleifera Lam. (MO-B) has better anti-inflammatory effects, with significant downregulation of inflammatory factors and inflammatory cells. MO-B can inhibit TLR4/NF-kappa B pathway cells and improve PI3K/AKT and MAPK pathways, suggesting it has the potential to be used as an anti-inflammatory agent in therapeutics or as an ingredient in functional foods.
JOURNAL OF FUNCTIONAL FOODS
(2023)
Article
Plant Sciences
Adhimoolam Karthikeyan, Hun Hwan Kim, Vetrivel Preethi, Mohammad Moniruzzaman, Ki Ho Lee, Senthil Kalaiselvi, Gon Sup Kim, Taesun Min
Summary: Citrus unshiu peel contains various flavonoids, with a high concentration of naringin. Treatment with flavonoids can reduce inflammation and oxidative damage in LPS-stimulated RAW 264.7 macrophages, showing potential for treating inflammation-related diseases.
Article
Biochemistry & Molecular Biology
Seungmin Yu, Hyejeong Park, Wooki Kim
Summary: Studies have shown that trehalose has beneficial effects on metabolic syndromes, hyperlipidemia, and autophagy, but its mechanisms of action are still not fully understood. This study aimed to investigate the effects of trehalose on immunological phenotypes, energy metabolism, and LPS-induced macrophage mitochondrial functioning. The results suggest that trehalose reduces inflammatory mediators in LPS-induced macrophages and suppresses inflammatory cytokines and mediators via energy metabolism reprogramming.
Review
Biochemistry & Molecular Biology
Jaeeun Lee, Min-Hyun Kim, Hyeyoung Kim
Summary: A moderate amount of ROS plays an important role in cell signaling and immune response, while excessive production can lead to inflammation and pathological conditions. The gastrointestinal mucosa is continuously exposed to ROS, increasing the risk of GI disorders. AST, a compound with antioxidant and anti-inflammatory properties, has shown protective effects against GI diseases through various mechanisms, including ROS neutralization, enhancement of antioxidant enzyme activity, and suppression of inflammation.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Agriculture, Dairy & Animal Science
Shuai Chen, Xin Wu, Jielin Duan, Pan Huang, Tiejun Li, Yulong Yin, Jie Yin
Summary: The study demonstrated that low-protein diets supplemented with glutamic acid or aspartic acid can improve oxidative stress-induced intestinal dysfunction in weaned piglets by reducing oxidative stress-related protein expression, lowering serum diamine oxidase levels, inhibiting intestinal epithelial cell apoptosis, alleviating abnormal energy metabolism, and maintaining intestinal barrier integrity.
Article
Biochemistry & Molecular Biology
A. N. M. Mamun-Or-Rashid, Tanzima Tarannum Lucy, Masayuki Yagi, Yoshikazu Yonei
Summary: This study found that astaxanthin has potential as a remedy for CML-HSA-induced inflammation and RANKL-induced excessive bone loss.
Article
Biochemistry & Molecular Biology
Shan Hong, Vermont P. Dia, Qixin Zhong
Summary: Co-nanoencapsulation of apigenin and curcumin showed synergistic anti-inflammatory effects in macrophages by reducing nitric oxide production, inhibiting pro-inflammatory cytokines expression, and enhancing the inhibition of intracellular reactive oxygen species.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Medicine, Research & Experimental
Yuan Tian, Siqi Zhou, Reiko Takeda, Kazuma Okazaki, Marie Sekita, Kazuichi Sakamoto
Summary: The study demonstrates that the anti-inflammatory effect of amber extract on RAW 264.7 cells may be mediated by inhibiting NF-κB p65 signaling pathway, providing a potential pharmacological alternative for inflammation-related diseases.
BIOMEDICINE & PHARMACOTHERAPY
(2021)
Article
Biotechnology & Applied Microbiology
Mohamad Rais Hasan, Che Azurahanim Che Abdullah, Mustapha Nor Afizah, Mohd Sabri Mohd Ghazali, Mohd Adzahan Noranizan
Summary: This study evaluates the efficacy of ultrasound in the extraction process of calcium hydroxyapatite (HAp). The findings show that low-intensity and moderate-intensity ultrasonication reduce the whiteness index and yield of HAp, while high-intensity ultrasonication reduces particle size and improves crystallinity.
FOOD AND BIOPRODUCTS PROCESSING
(2024)
Article
Biotechnology & Applied Microbiology
Barbara Flaibam, Rosana Goldbeck
Summary: This study evaluated the possibility of extracting proteins and obtaining hydrolysates from non-animal agro-industrial waste using enzymes for the production of cultured meat inputs. Results showed that the application of enzymes can maximize the use of protein from these wastes, providing a low-cost and environmentally friendly route with nutritional potential for cultured meat.
FOOD AND BIOPRODUCTS PROCESSING
(2024)
Article
Biotechnology & Applied Microbiology
Robson Costa de Sousa, Ariany Binda Silva Costa, Marcos Daniel Martins Freitas, Maisa Tonon Bitti Perazzini, Hugo Perazzini
Summary: This study investigated the drying kinetics of black pepper through experimental and mathematical modeling approaches. The models developed provided valuable insights into the coupling between heat and mass transfers during the drying process, and accurately described the drying behavior of black pepper.
FOOD AND BIOPRODUCTS PROCESSING
(2024)
Article
Biotechnology & Applied Microbiology
Ali Nikkhah, Hasan Nikkhah, Amir Shahbazi, Mona Kamelan Zargar Zarin, Duygu Beykal Iz, Mohammad-Taghi Ebadi, Mohammad Fakhroleslam, Burcu Beykal
Summary: Cumin and eucalyptus essential oils were enriched to meet ISO standards using a dynamic fractional distillation process. The optimization results showed low operating costs and potential for improving process efficiency.
FOOD AND BIOPRODUCTS PROCESSING
(2024)
Article
Biotechnology & Applied Microbiology
Sakshi Gupta, Gargi Ghoshal
Summary: A study was conducted to prepare green gram protein hydrogel enriched with curcumin and evaluate its physicochemical properties. The results showed that the hydrogel had high encapsulation efficiency, swelling capacity, and antioxidant property. Furthermore, applying the hydrogel as a coating on tomatoes and apples proved to be effective.
FOOD AND BIOPRODUCTS PROCESSING
(2024)
Article
Biotechnology & Applied Microbiology
Calvin Lo, Rene H. Wijffels, Michel H. M. Eppink
Summary: This study developed a novel strategy to separate dissolved oils from imidazole/hexanoic acid mixture and regenerate the solvent using polar antisolvents. By adding small amounts of water and methanol, high recovery of lipids was achieved, while ethanol required a large amount and caused solvent dilution.
FOOD AND BIOPRODUCTS PROCESSING
(2024)
Article
Biotechnology & Applied Microbiology
Manoj Sawale, Patnarin Benyathiar, Pablo Coronel, Ajay Rawat, Josip Simunovic, Ferhan Ozadali, Dharmendra K. Mishra
Summary: Microwave and ohmic heating are popular choices for aseptic processing due to their rapid heating capabilities and better product quality. This study aims to find an alternative approach to simulate processing conditions by modeling and validating the process using surrogate particles and microorganisms. A mathematical model was used to simulate heat transfer in fluid and solid particles. The process was validated using simulated particles and surrogate microorganisms, with magnetic implants in spherical particles to measure residence time distribution. The microwave aseptic system was successfully validated for producing shelf-stable particulate food products.
FOOD AND BIOPRODUCTS PROCESSING
(2024)