标题
The Role of the BCL-2 Family of Proteins in HIV-1 Pathogenesis and Persistence
作者
关键词
-
出版物
CLINICAL MICROBIOLOGY REVIEWS
Volume 33, Issue 1, Pages -
出版商
American Society for Microbiology
发表日期
2019-10-29
DOI
10.1128/cmr.00107-19
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Modeling HIV-1 latency using primary CD4+ T cells from HIV-1 infected ART suppressed individuals
- (2019) Hiroshi Takata et al. JOURNAL OF VIROLOGY
- Naïve CD4+ T Cells Harbor a Large Inducible Reservoir of Latent, Replication-Competent HIV-1
- (2019) Jennifer M Zerbato et al. CLINICAL INFECTIOUS DISEASES
- Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
- (2018) Lorenzo Galluzzi et al. CELL DEATH AND DIFFERENTIATION
- Getting the “Kill” into “Shock and Kill”: Strategies to Eliminate Latent HIV
- (2018) Youry Kim et al. Cell Host & Microbe
- Small-molecule Mcl-1 inhibitors: Emerging anti-tumor agents
- (2018) Yichao Wan et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- The role of latency reversal agents in the cure of HIV: A review of current data
- (2018) Kiandokht Bashiri et al. IMMUNOLOGY LETTERS
- Latent HIV reservoirs exhibit inherent resistance to elimination by CD8+ T cells
- (2018) Szu-Han Huang et al. JOURNAL OF CLINICAL INVESTIGATION
- HIV Protease-Generated Casp8p41, When Bound and Inactivated by Bcl2, Is Degraded by the Proteasome
- (2018) Sekar Natesampillai et al. JOURNAL OF VIROLOGY
- Metabolically active CD4+ T cells expressing Glut1 and OX40 preferentially harbor HIV during in vitro infection
- (2017) Clovis S. Palmer et al. FEBS LETTERS
- CTLA-4 + PD-1 − Memory CD4 + T Cells Critically Contribute to Viral Persistence in Antiretroviral Therapy-Suppressed, SIV-Infected Rhesus Macaques
- (2017) Colleen S. McGary et al. IMMUNITY
- Caspase-8: regulating life and death
- (2017) Bart Tummers et al. IMMUNOLOGICAL REVIEWS
- Interval dosing with the HDAC inhibitor vorinostat effectively reverses HIV latency
- (2017) Nancie M. Archin et al. JOURNAL OF CLINICAL INVESTIGATION
- Clonal expansion of genome-intact HIV-1 in functionally polarized Th1 CD4+ T cells
- (2017) Guinevere Q. Lee et al. JOURNAL OF CLINICAL INVESTIGATION
- Maintenance of the HIV Reservoir Is Antagonized by Selective BCL2 Inhibition
- (2017) Nathan W. Cummins et al. JOURNAL OF VIROLOGY
- From basic apoptosis discoveries to advanced selective BCL-2 family inhibitors
- (2017) Avi Ashkenazi et al. NATURE REVIEWS DRUG DISCOVERY
- Identification of Genetically Intact HIV-1 Proviruses in Specific CD4 + T Cells from Effectively Treated Participants
- (2017) Bonnie Hiener et al. Cell Reports
- HIV-related proteins prolong macrophage survival through induction of Triggering receptor expressed on myeloid cells-1
- (2017) Zhihong Yuan et al. Scientific Reports
- HIV-infected macrophages and microglia that survive acute infection become viral reservoirs by a mechanism involving Bim
- (2017) Paul Castellano et al. Scientific Reports
- Inflammation Perturbs the IL-7 Axis, Promoting Senescence and Exhaustion that Broadly Characterize Immune Failure in Treated HIV Infection
- (2016) Carey L. Shive et al. JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
- Interleukins (from IL-1 to IL-38), interferons, transforming growth factor β, and TNF-α: Receptors, functions, and roles in diseases
- (2016) Mübeccel Akdis et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Cytokines and T-Cell Homeostasis in HIV Infection
- (2016) Michael L. Freeman et al. JOURNAL OF INFECTIOUS DISEASES
- Prime, Shock, and Kill: Priming CD4 T Cells from HIV Patients with a BCL-2 Antagonist before HIV Reactivation Reduces HIV Reservoir Size
- (2016) Nathan W. Cummins et al. JOURNAL OF VIROLOGY
- HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay
- (2016) Sara Sunshine et al. JOURNAL OF VIROLOGY
- PD-1+ and follicular helper T cells are responsible for persistent HIV-1 transcription in treated aviremic individuals
- (2016) Riddhima Banga et al. NATURE MEDICINE
- Distinct Patterns of Bcl-2 Expression Occur in R5- and X4-Tropic HIV-1-Producing Lymphoid Tissue Cells Infected Ex Vivo
- (2015) Michelle K. Haas et al. AIDS RESEARCH AND HUMAN RETROVIRUSES
- Combination with vorinostat overcomes ABT-263 (navitoclax) resistance of small cell lung cancer
- (2015) Wataru Nakajima et al. CANCER BIOLOGY & THERAPY
- BCL-2 Antagonism to Target the Intrinsic Mitochondrial Pathway of Apoptosis
- (2015) C. J. Gibson et al. CLINICAL CANCER RESEARCH
- A Subset of CD4/CD8 Double-Negative T Cells Expresses HIV Proteins in Patients on Antiretroviral Therapy
- (2015) Laura K. DeMaster et al. JOURNAL OF VIROLOGY
- Potent and selective small-molecule MCL-1 inhibitors demonstrate on-target cancer cell killing activity as single agents and in combination with ABT-263 (navitoclax)
- (2015) J D Leverson et al. Cell Death & Disease
- T Memory Stem Cells and HIV: a Long-Term Relationship
- (2015) Ann Chahroudi et al. Current HIV/AIDS Reports
- HIV-1 Tat affects the programming and functionality of human CD8+ T cells by modulating the expression of T-box transcription factors
- (2014) Fabio Sforza et al. AIDS
- Triggering Receptor Expressed on Myeloid Cells 1 (TREM-1)-mediated Bcl-2 Induction Prolongs Macrophage Survival
- (2014) Zhihong Yuan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Casp8p41 generated by HIV protease kills CD4 T cells through direct Bak activation
- (2014) Amy M. Sainski et al. JOURNAL OF CELL BIOLOGY
- An In Vitro System to Model the Establishment and Reactivation of HIV-1 Latency
- (2014) A. Marini et al. JOURNAL OF IMMUNOLOGY
- Tat-Induced FOXO3a Is a Key Mediator of Apoptosis in HIV-1-Infected Human CD4+ T Lymphocytes
- (2014) A. Dabrowska et al. JOURNAL OF IMMUNOLOGY
- Inflammatory Cytokines Drive CD4+ T-Cell Cycling and Impaired Responsiveness to Interleukin 7: Implications for Immune Failure in HIV Disease
- (2014) Carey L. Shive et al. JOURNAL OF INFECTIOUS DISEASES
- Type I interferon responses in rhesus macaques prevent SIV infection and slow disease progression
- (2014) Netanya G. Sandler et al. NATURE
- HIV-1 persistence in CD4+ T cells with stem cell–like properties
- (2014) Maria J Buzon et al. NATURE MEDICINE
- A primary CD4+ T cell model of HIV-1 latency established after activation through the T cell receptor and subsequent return to quiescence
- (2014) Michelle Kim et al. Nature Protocols
- Necroptosis Takes Place in Human Immunodeficiency Virus Type-1 (HIV-1)-Infected CD4+ T Lymphocytes
- (2014) Ting Pan et al. PLoS One
- Progressive contraction of the latent HIV reservoir around a core of less-differentiated CD4+ memory T Cells
- (2014) S. Jaafoura et al. Nature Communications
- Apoptosis and Molecular Targeting Therapy in Cancer
- (2014) Mohamed Hassan et al. Biomed Research International
- Panobinostat, a histone deacetylase inhibitor, for latent-virus reactivation in HIV-infected patients on suppressive antiretroviral therapy: a phase 1/2, single group, clinical trial
- (2014) Thomas A Rasmussen et al. Lancet HIV
- Interleukin-7 promotes HIV persistence during antiretroviral therapy
- (2013) C. Vandergeeten et al. BLOOD
- Replication-Competent Noninduced Proviruses in the Latent Reservoir Increase Barrier to HIV-1 Cure
- (2013) Ya-Chi Ho et al. CELL
- Bax Crystal Structures Reveal How BH3 Domains Activate Bax and Nucleate Its Oligomerization to Induce Apoptosis
- (2013) Peter E. Czabotar et al. CELL
- Cancer therapeutics: Targeting the apoptotic pathway
- (2013) Khurum H. Khan et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
- The Presence of HIV-1 Tat Protein Second Exon Delays Fas Protein-mediated Apoptosis in CD4+T Lymphocytes
- (2013) María Rosa López-Huertas et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Programmed Death-1 Is a Marker for Abnormal Distribution of Naive/Memory T Cell Subsets in HIV-1 Infection
- (2013) G. Breton et al. JOURNAL OF IMMUNOLOGY
- HIV-Specific CD8+ T Cells from Elite Controllers Are Primed for Survival
- (2013) J. Yan et al. JOURNAL OF VIROLOGY
- Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection
- (2013) Gilad Doitsh et al. NATURE
- ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets
- (2013) Andrew J Souers et al. NATURE MEDICINE
- Interferon-α Is the Primary Plasma Type-I IFN in HIV-1 Infection and Correlates with Immune Activation and Disease Markers
- (2013) Gareth A. D. Hardy et al. PLoS One
- Proteasome inhibitors act as bifunctional antagonists of human immunodeficiency virus type 1 latency and replication
- (2013) Leia K Miller et al. Retrovirology
- Multiple Functions of BCL-2 Family Proteins
- (2013) J. M. Hardwick et al. Cold Spring Harbor Perspectives in Biology
- Mechanisms of Action of Bcl-2 Family Proteins
- (2013) A. Shamas-Din et al. Cold Spring Harbor Perspectives in Biology
- HIV Latency
- (2013) R. F. Siliciano et al. Cold Spring Harbor Perspectives in Medicine
- Type I Interferon Upregulates Bak and Contributes to T Cell Loss during Human Immunodeficiency Virus (HIV) Infection
- (2013) Joseph A. Fraietta et al. PLoS Pathogens
- Regulation of the Intrinsic Apoptosis Pathway by Reactive Oxygen Species
- (2012) Chu-Chiao Wu et al. ANTIOXIDANTS & REDOX SIGNALING
- Follicular helper T cells serve as the major CD4 T cell compartment for HIV-1 infection, replication, and production
- (2012) Matthieu Perreau et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Shock and kill
- (2012) Steven G. Deeks NATURE
- CCL21/CCR7 Prevents Apoptosis via the ERK Pathway in Human Non-Small Cell Lung Cancer Cells
- (2012) Ying Xu et al. PLoS One
- HIV-1 Induced Bystander Apoptosis
- (2012) Himanshu Garg et al. Viruses-Basel
- Directly Infected Resting CD4+T Cells Can Produce HIV Gag without Spreading Infection in a Model of HIV Latency
- (2012) Matthew J. Pace et al. PLoS Pathogens
- In Vitro and In Vivo Selective Antitumor Activity of a Novel Orally Bioavailable Proteasome Inhibitor MLN9708 against Multiple Myeloma Cells
- (2011) Dharminder Chauhan et al. CLINICAL CANCER RESEARCH
- Virally induced changes in cellular microRNAs maintain latency of human cytomegalovirus in CD34+ progenitors
- (2011) E. Poole et al. JOURNAL OF GENERAL VIROLOGY
- A Unified Model of Mammalian BCL-2 Protein Family Interactions at the Mitochondria
- (2011) Fabien Llambi et al. MOLECULAR CELL
- A human memory T cell subset with stem cell–like properties
- (2011) Luca Gattinoni et al. NATURE MEDICINE
- Expression and reactivation of HIV in a chemokine induced model of HIV latency in primary resting CD4+ T cells
- (2011) Suha Saleh et al. Retrovirology
- Myeloid dendritic cells in HIV-1 infection
- (2011) Nina Derby et al. Current Opinion in HIV and AIDS
- ABT-737 synergizes with Bortezomib to kill melanoma cells
- (2011) S. N. Reuland et al. Biology Open
- Acquired resistance to ABT-737 in lymphoma cells that up-regulate MCL-1 and BFL-1
- (2010) D. Yecies et al. BLOOD
- Both CD31+and CD31−Naive CD4+T Cells Are Persistent HIV Type 1–Infected Reservoirs in Individuals Receiving Antiretroviral Therapy
- (2010) Fiona Wightman et al. JOURNAL OF INFECTIOUS DISEASES
- Blood Myeloid Dendritic Cells from HIV-1-Infected Individuals Display a Proapoptotic Profile Characterized by Decreased Bcl-2 Levels and by Caspase-3+ Frequencies That Are Associated with Levels of Plasma Viremia and T Cell Activation in an Exploratory Study
- (2010) S. M. Dillon et al. JOURNAL OF VIROLOGY
- BH3-Triggered Structural Reorganization Drives the Activation of Proapoptotic BAX
- (2010) Evripidis Gavathiotis et al. MOLECULAR CELL
- HIV-1 infects multipotent progenitor cells causing cell death and establishing latent cellular reservoirs
- (2010) Christoph C Carter et al. NATURE MEDICINE
- Autophagy and HIV
- (2010) Christina Dinkins et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Mechanisms of HIV-associated lymphocyte apoptosis: 2010
- (2010) N W Cummins et al. Cell Death & Disease
- Antiretroviral therapy initiation during primary HIV infection enhances both CD127 expression and the proliferative capacity of HIV-specific CD8+ T cells
- (2009) Camille Lécuroux et al. AIDS
- BAKandBAXdeletion using zinc-finger nucleases yields apoptosis-resistant CHO cells
- (2009) Gregory J. Cost et al. BIOTECHNOLOGY AND BIOENGINEERING
- IL-10 is up-regulated in multiple cell types during viremic HIV infection and reversibly inhibits virus-specific T cells
- (2009) M. A. Brockman et al. BLOOD
- Chemokine receptors CXCR4 and CCR7 promote metastasis by preventing anoikis in cancer cells
- (2009) M Kochetkova et al. CELL DEATH AND DIFFERENTIATION
- Autophagy pathway intersects with HIV-1 biosynthesis and regulates viral yields in macrophages
- (2009) George B. Kyei et al. JOURNAL OF CELL BIOLOGY
- Small-molecule screening using a human primary cell model of HIV latency identifies compounds that reverse latency without cellular activation
- (2009) Hung-Chih Yang et al. JOURNAL OF CLINICAL INVESTIGATION
- Stepwise Activation of BAX and BAK by tBID, BIM, and PUMA Initiates Mitochondrial Apoptosis
- (2009) Hyungjin Kim et al. MOLECULAR CELL
- HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation
- (2009) Nicolas Chomont et al. NATURE MEDICINE
- ABT-263: A Potent and Orally Bioavailable Bcl-2 Family Inhibitor
- (2008) C. Tse et al. CANCER RESEARCH
- S-phase entry leads to cell death in circulating T cells from HIV-infected persons
- (2008) S. F. Sieg et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Tumor transfected with CCL21 enhanced reactivity and apoptosis resistance of human monocyte-derived dendritic cells
- (2007) Sha Wu et al. IMMUNOBIOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now