The Role of Iron and Siderophores in Infection, and the Development of Siderophore Antibiotics
出版年份 2019 全文链接
标题
The Role of Iron and Siderophores in Infection, and the Development of Siderophore Antibiotics
作者
关键词
-
出版物
CLINICAL INFECTIOUS DISEASES
Volume 69, Issue Supplement_7, Pages S529-S537
出版商
Oxford University Press (OUP)
发表日期
2019-09-01
DOI
10.1093/cid/ciz825
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Complexes formed by the siderophore-based monosulfactam antibiotic BAL30072 and their interaction with the outer membrane receptor PiuA of P. aeruginosa
- (2019) Mariano Andrea Scorciapino et al. BIOMETALS
- Pharmacodynamics of cefiderocol, a novel siderophore cephalosporin, in a Pseudomonas aeruginosa neutropenic murine thigh model
- (2018) Islam M. Ghazi et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Humanized Exposures of Cefiderocol, a Siderophore Cephalosporin, Display Sustained in vivo Activity against Siderophore-Resistant Pseudomonas aeruginosa
- (2018) Islam M. Ghazi et al. PHARMACOLOGY
- ARGONAUT-I: Activity of Cefiderocol (S-649266), a Siderophore Cephalosporin, against Gram-Negative Bacteria, Including Carbapenem-Resistant Nonfermenters and Enterobacteriaceae with Defined Extended-Spectrum β-Lactamases and Carbapenemases
- (2018) Michael R. Jacobs et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Cefiderocol versus imipenem-cilastatin for the treatment of complicated urinary tract infections caused by Gram-negative uropathogens: a phase 2, randomised, double-blind, non-inferiority trial
- (2018) Simon Portsmouth et al. LANCET INFECTIOUS DISEASES
- Pharmacokinetics, Safety, and Tolerability Evaluation of Single and Multiple Doses of GSK3342830 in Healthy Volunteers
- (2018) David Tenero et al. Clinical Pharmacology in Drug Development
- 1351. In vitro Activity of Cefiderocol (S-649266), a Siderophore Cephalosporin, Against Enterobacteriaceae With Defined Extended-Spectrum Β-Lactamases and Carbapenemases
- (2018) Michael R Jacobs et al. Open Forum Infectious Diseases
- Activity of the novel siderophore cephalosporin cefiderocol against multidrug-resistant Gram-negative pathogens
- (2017) J. Dobias et al. EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
- Activity of cefiderocol (S-649266) against carbapenem-resistant Gram-negative bacteria collected from inpatients in Greek hospitals
- (2017) Matthew E. Falagas et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- What we may expect from novel antibacterial agents in the pipeline with respect to resistance and pharmacodynamic principles
- (2017) Karen Bush et al. JOURNAL OF PHARMACOKINETICS AND PHARMACODYNAMICS
- Coordination of Bactericidal and Iron Regulatory Functions of Hepcidin in Innate Antimicrobial Immunity in a Zebrafish Model
- (2017) Xiao-feng Jiang et al. Scientific Reports
- Stability of Novel Siderophore Cephalosporin S-649266 against Clinically Relevant Carbapenemases
- (2016) Tsukasa Ito-Horiyama et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Adaptive resistance to antibiotics in bacteria: a systems biology perspective
- (2016) Santiago Sandoval-Motta et al. Wiley Interdisciplinary Reviews-Systems Biology and Medicine
- Structural basis for haem piracy from host haemopexin by Haemophilus influenzae
- (2016) Silvia Zambolin et al. Nature Communications
- Coordination Chemistry of Microbial Iron Transport
- (2015) Kenneth N. Raymond et al. ACCOUNTS OF CHEMICAL RESEARCH
- Pharmacodynamic Profiling of a Siderophore-Conjugated Monocarbam in Pseudomonas aeruginosa: Assessing the Risk for Resistance and Attenuated Efficacy
- (2015) Aryun Kim et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Potentiation of Antibacterial Activity of the MB-1 Siderophore-Monobactam Conjugate Using an Efflux Pump Inhibitor
- (2015) Andrew P. Tomaras et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- In VitroAntimicrobial Activity of a Siderophore Cephalosporin, S-649266, against Enterobacteriaceae Clinical Isolates, Including Carbapenem-Resistant Strains
- (2015) Naoki Kohira et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Discovery of Efficacious Pseudomonas aeruginosa-Targeted Siderophore-Conjugated Monocarbams by Application of a Semi-mechanistic Pharmacokinetic/Pharmacodynamic Model
- (2015) Kerry E. Murphy-Benenato et al. JOURNAL OF MEDICINAL CHEMISTRY
- SAR and Structural Analysis of Siderophore-Conjugated Monocarbam Inhibitors of Pseudomonas aeruginosa PBP3
- (2015) Kerry E. Murphy-Benenato et al. ACS Medicinal Chemistry Letters
- Adaptive Resistance in Bacteria Requires Epigenetic Inheritance, Genetic Noise, and Cost of Efflux Pumps
- (2015) Santiago Sandoval Motta et al. PLoS One
- Heme uptake in bacterial pathogens
- (2014) Heidi Contreras et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Adaptation of Iron Homeostasis Pathways by a Pseudomonas aeruginosa Pyoverdine Mutant in the Cystic Fibrosis Lung
- (2014) A. T. Nguyen et al. JOURNAL OF BACTERIOLOGY
- Coordinated Rearrangements between Cytoplasmic and Periplasmic Domains of the Membrane Protein Complex ExbB-ExbD of Escherichia coli
- (2014) Aleksandr Sverzhinsky et al. STRUCTURE
- Siderocalin Outwits the Coordination Chemistry of Vibriobactin, a Siderophore of Vibrio cholerae
- (2013) Benjamin E. Allred et al. ACS Chemical Biology
- Siderophore conjugates
- (2013) Malcolm G. P. Page Annals of the New York Academy of Sciences
- Involvement of Fe Uptake Systems and AmpC β-Lactamase in Susceptibility to the Siderophore Monosulfactam BAL30072 in Pseudomonas aeruginosa
- (2013) Christian van Delden et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Adaptation-Based Resistance to Siderophore-Conjugated Antibacterial Agents by Pseudomonas aeruginosa
- (2013) Andrew P. Tomaras et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Iron deficiency and susceptibility to infections: evaluation of the clinical evidence
- (2013) G. S. Tansarli et al. EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
- Pyridone-Conjugated Monobactam Antibiotics with Gram-Negative Activity
- (2013) Matthew F. Brown et al. JOURNAL OF MEDICINAL CHEMISTRY
- Pseudomonas aeruginosa adapts its iron uptake strategies in function of the type of infections
- (2013) Pierre Cornelis et al. Frontiers in Cellular and Infection Microbiology
- Iron, copper, zinc, and manganese transport and regulation in pathogenic Enterobacteria: correlations between strains, site of infection and the relative importance of the different metal transport systems for virulence
- (2013) Gaëlle Porcheron et al. Frontiers in Cellular and Infection Microbiology
- Biosynthesis of Albomycin δ2 Provides a Template for Assembling Siderophore and Aminoacyl-tRNA Synthetase Inhibitor Conjugates
- (2012) Yu Zeng et al. ACS Chemical Biology
- Clinically Relevant Gram-Negative Resistance Mechanisms Have No Effect on the Efficacy of MC-1, a Novel Siderophore-Conjugated Monocarbam
- (2012) Craig J. McPherson et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- NGAL-Siderocalin in kidney disease
- (2012) Neal Paragas et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Characterization of the aqueous iron(III) chelation chemistry of a potential Trojan Horse antimicrobial agent: chelate structure, stability and pH dependent speciation
- (2012) James M. Harrington et al. BIOMETALS
- Chemical syntheses and in vitro antibacterial activity of two desferrioxamine B-ciprofloxacin conjugates with potential esterase and phosphatase triggered drug release linkers
- (2012) Cheng Ji et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Siderocalins: Siderophore binding proteins evolved for primary pathogen host defense
- (2012) Allyson K Sia et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Mammalian Siderophores, Siderophore-binding Lipocalins, and the Labile Iron Pool
- (2012) Colin Correnti et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Immune Interference inMycobacterium tuberculosisIntracellular Iron Acquisition through Siderocalin Recognition of Carboxymycobactins
- (2011) Trisha M. Hoette et al. ACS Chemical Biology
- In vitro activity of BAL30072 against Burkholderia pseudomallei
- (2011) Takehiko Mima et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Adaptive resistance to cationic compounds in Pseudomonas aeruginosa
- (2011) Anna Skiada et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Distinctive Attributes of β-Lactam Target Proteins inAcinetobacter baumanniiRelevant to Development of New Antibiotics
- (2011) Seungil Han et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Iron Homeostasis and the Inflammatory Response
- (2010) Marianne Wessling-Resnick Annual Review of Nutrition
- Mechanism of Bactericidal Activity of Microcin L inEscherichia coliandSalmonella enterica
- (2010) Natacha Morin et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Adaptive Resistance to the "Last Hope" Antibiotics Polymyxin B and Colistin in Pseudomonas aeruginosa Is Mediated by the Novel Two-Component Regulatory System ParR-ParS
- (2010) L. Fernandez et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- In Vitro Properties of BAL30072, a Novel Siderophore Sulfactam with Activity against Multiresistant Gram-Negative Bacilli
- (2010) M. G. P. Page et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Siderophore uptake in bacteria and the battle for iron with the host; a bird’s eye view
- (2010) Byron C. Chu et al. BIOMETALS
- The struggle for iron - a metal at the host-pathogen interface
- (2010) Manfred Nairz et al. CELLULAR MICROBIOLOGY
- The Role of Iron and Chelators on Infections in Iron Overload and Non Iron Loaded Conditions: Prospects for the Design of New Antimicrobial Therapies
- (2010) George J. Kontoghiorghes et al. HEMOGLOBIN
- Chemistry and biology of siderophores
- (2010) Robert C. Hider et al. NATURAL PRODUCT REPORTS
- Structural basis for effectiveness of siderophore-conjugated monocarbams against clinically relevant strains of Pseudomonas aeruginosa
- (2010) S. Han et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Isolation and Characterization of Two Members of the Siderophore-Microcin Family, Microcins M and H47
- (2009) G. Vassiliadis et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Siderophores as drug delivery agents: application of the “Trojan Horse” strategy
- (2009) Ute Möllmann et al. BIOMETALS
- Sideromycins: tools and antibiotics
- (2009) Volkmar Braun et al. BIOMETALS
- Heme uptake across the outer membrane as revealed by crystal structures of the receptor-hemophore complex
- (2009) S. Krieg et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Bacterial heme-transport proteins and their heme-coordination modes
- (2008) Yong Tong et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Investigations of the MceIJ-Catalyzed Posttranslational Modification of the Microcin E492 C-Terminus: Linkage of Ribosomal and Nonribosomal Peptides To Form “Trojan Horse” Antibiotics†
- (2008) Elizabeth M. Nolan et al. BIOCHEMISTRY
- The Siderocalin/Enterobactin Interaction: A Link between Mammalian Immunity and Bacterial Iron Transport1
- (2008) Rebecca J. Abergel et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
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