Humanized Exposures of Cefiderocol, a Siderophore Cephalosporin, Display Sustained in vivo Activity against Siderophore-Resistant Pseudomonas aeruginosa

Understanding the mechanisms and drivers of antimicrobial resistance

(2016) Alison H Holmes et al.   LANCET

Pharmacodynamic Profiling of a Siderophore-Conjugated Monocarbam in Pseudomonas aeruginosa: Assessing the Risk for Resistance and Attenuated Efficacy

(2015) Aryun Kim et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Potentiation of Antibacterial Activity of the MB-1 Siderophore-Monobactam Conjugate Using an Efflux Pump Inhibitor

(2015) Andrew P. Tomaras et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In VivoActivities of Simulated Human Doses of Cefepime and Cefepime-AAI101 against Multidrug-Resistant Gram-Negative Enterobacteriaceae

(2015) Jared L. Crandon et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In VitroAntimicrobial Activity of a Siderophore Cephalosporin, S-649266, against Enterobacteriaceae Clinical Isolates, Including Carbapenem-Resistant Strains

(2015) Naoki Kohira et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In vitroantimicrobial activity of S-649266, a catechol-substituted siderophore cephalosporin, when tested against non-fermenting Gram-negative bacteria

(2015) Akinobu Ito et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Multidrug evolutionary strategies to reverse antibiotic resistance

(2015) M. Baym et al.   SCIENCE

Adaptation-Based Resistance to Siderophore-Conjugated Antibacterial Agents by Pseudomonas aeruginosa

(2013) Andrew P. Tomaras et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Targeting iron assimilation to develop new antibacterials

(2012) Timothy L Foley et al.   Expert Opinion on Drug Discovery

Design, Synthesis, and Study of a Mycobactin−Artemisinin Conjugate That Has Selective and Potent Activity against Tuberculosis and Malaria

(2011) Marvin J. Miller et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Utilization of microbial iron assimilation processes for the development of new antibiotics and inspiration for the design of new anticancer agents

(2009) Marvin J. Miller et al.   BIOMETALS

Sideromycins: tools and antibiotics

(2009) Volkmar Braun et al.   BIOMETALS