A Bottom-Up Whole-Body Physiologically Based Pharmacokinetic Model to Mechanistically Predict Tissue Distribution and the Rate of Subcutaneous Absorption of Therapeutic Proteins

标题
A Bottom-Up Whole-Body Physiologically Based Pharmacokinetic Model to Mechanistically Predict Tissue Distribution and the Rate of Subcutaneous Absorption of Therapeutic Proteins
作者
关键词
PBPK, pharmacokinetics, simulation, subcutaneous absorption, therapeutic protein
出版物
AAPS Journal
Volume 18, Issue 1, Pages 156-170
出版商
American Association of Pharmaceutical Scientists (AAPS)
发表日期
2015-09-26
DOI
10.1208/s12248-015-9819-4

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