Peptide-Based Molecular Strategies To Interfere with Protein Misfolding, Aggregation, and Cell Degeneration
出版年份 2019 全文链接
标题
Peptide-Based Molecular Strategies To Interfere with Protein Misfolding, Aggregation, and Cell Degeneration
作者
关键词
-
出版物
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume -, Issue -, Pages -
出版商
Wiley
发表日期
2019-09-17
DOI
10.1002/anie.201906908
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- The proteostasis network and its decline in ageing
- (2019) Mark S. Hipp et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- α-Sheet secondary structure in amyloid β-peptide drives aggregation and toxicity in Alzheimer’s disease
- (2019) Dylan Shea et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Secondary nucleation and elongation occur at different sites on Alzheimer’s amyloid-β aggregates
- (2019) Tom Scheidt et al. Science Advances
- Designed Macrocyclic Peptides as Nanomolar Amyloid Inhibitors Based on Minimal Recognition Elements
- (2018) Anna Spanopoulou et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Improving oral bioavailability of cyclic peptides by N -methylation
- (2018) Andreas F.B. Räder et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Peptide chemistry toolbox – Transforming natural peptides into peptide therapeutics
- (2018) Miloš Erak et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Inhibition of tau-derived hexapeptide aggregation and toxicity by a self-assembled cyclic d,l-α-peptide conformational inhibitor
- (2018) A. Belostozky et al. CHEMICAL COMMUNICATIONS
- In Vitro Potency and Preclinical Pharmacokinetic Comparison of All-D-Enantiomeric Peptides Developed for the Treatment of Alzheimer’s Disease
- (2018) Elena Schartmann et al. JOURNAL OF ALZHEIMERS DISEASE
- BRICHOS domain of Bri2 inhibits islet amyloid polypeptide (IAPP) fibril formation and toxicity in human beta cells
- (2018) Marie E. Oskarsson et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Exploiting the therapeutic potential of ready-to-use drugs: Repurposing antibiotics against amyloid aggregation in neurodegenerative diseases
- (2018) Sergio B. Socias et al. PROGRESS IN NEUROBIOLOGY
- The Physiological Roles of Amyloid-β Peptide Hint at New Ways to Treat Alzheimer's Disease
- (2018) Holly M. Brothers et al. Frontiers in Aging Neuroscience
- Cryo-EM structure of alpha-synuclein fibrils
- (2018) Ricardo Guerrero-Ferreira et al. eLife
- Impact of nanoparticles on amyloid peptide and protein aggregation: a review with a focus on gold nanoparticles
- (2018) Torsten John et al. Nanoscale
- The amyloid hypothesis on trial
- (2018) Simon Makin NATURE
- Common fibrillar spines of amyloid-β and human islet amyloid polypeptide revealed by microelectron diffraction and structure-based inhibitors
- (2017) Pascal Krotee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Key aromatic/hydrophobic amino acids controlling a cross-amyloid peptide interaction versus amyloid self-assembly
- (2017) Maria Bakou et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Current State of Peptide Drug Discovery: Back to the Future?
- (2017) Antoine Henninot et al. JOURNAL OF MEDICINAL CHEMISTRY
- Backbone Engineering within a Latent β-Hairpin Structure to Design Inhibitors of Polyglutamine Amyloid Formation
- (2017) Karunakar Kar et al. JOURNAL OF MOLECULAR BIOLOGY
- Structure-based inhibitors of tau aggregation
- (2017) P. M. Seidler et al. Nature Chemistry
- Monomeric and fibrillar α-synuclein exert opposite effects on the catalytic cycle that promotes the proliferation of Aβ42 aggregates
- (2017) Sean Chia et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Rationally Designed Peptides and Peptidomimetics as Inhibitors of Amyloid-β (Aβ) Aggregation: Potential Therapeutics of Alzheimer’s Disease
- (2017) Deepti Goyal et al. ACS Combinatorial Science
- Noncerebral Amyloidoses: Aspects on Seeding, Cross-Seeding, and Transmission
- (2017) Gunilla T. Westermark et al. Cold Spring Harbor Perspectives in Medicine
- Chaperones as Suppressors of Protein Misfolded Oligomer Toxicity
- (2017) Benedetta Mannini et al. Frontiers in Molecular Neuroscience
- Targeting Apolipoprotein E/Amyloid β Binding by Peptoid CPO_Aβ17-21 P Ameliorates Alzheimer’s Disease Related Pathology and Cognitive Decline
- (2017) Shan Liu et al. Scientific Reports
- TANGO-Inspired Design of Anti-Amyloid Cyclic Peptides
- (2016) Xiaomeng Lu et al. ACS Chemical Neuroscience
- Alpha-crystallin-derived peptides as therapeutic chaperones
- (2016) Murugesan Raju et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Functional sequences in human alphaB crystallin
- (2016) John I. Clark BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Structure and function of α-crystallins: Traversing from in vitro to in vivo
- (2016) Martin Haslbeck et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Self-Assembled Cyclic d,l -α-Peptides as Generic Conformational Inhibitors of the α-Synuclein Aggregation and Toxicity: In Vitro and Mechanistic Studies
- (2016) Marina Chemerovski-Glikman et al. CHEMISTRY-A EUROPEAN JOURNAL
- Peptide Inhibitors of the amyloidogenesis of IAPP: verification of the hairpin-binding geometry hypothesis
- (2016) Kalkena Sivanesam et al. FEBS LETTERS
- Cross-interactions between the Alzheimer Disease Amyloid-β Peptide and Other Amyloid Proteins: A Further Aspect of the Amyloid Cascade Hypothesis
- (2016) Jinghui Luo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Peptides Composed of Alternating L- and D-Amino Acids Inhibit Amyloidogenesis in Three Distinct Amyloid Systems Independent of Sequence
- (2016) Jackson Kellock et al. JOURNAL OF MOLECULAR BIOLOGY
- Switchable photooxygenation catalysts that sense higher-order amyloid structures
- (2016) Atsuhiko Taniguchi et al. Nature Chemistry
- Cross-talk between amyloidogenic proteins in type-2 diabetes and Parkinson’s disease
- (2016) Istvan Horvath et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Cyclic Peptide Mimic of the β-Amyloid Binding Domain on Transthyretin
- (2015) Patricia Y. Cho et al. ACS Chemical Neuroscience
- In Vivo Seeding and Cross-Seeding of Localized Amyloidosis
- (2015) Marie E. Oskarsson et al. AMERICAN JOURNAL OF PATHOLOGY
- Contact between the β1 and β2 Segments of α-Synuclein that Inhibits Amyloid Formation
- (2015) Hamed Shaykhalishahi et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- A Hot-Segment-Based Approach for the Design of Cross-Amyloid Interaction Surface Mimics as Inhibitors of Amyloid Self-Assembly
- (2015) Erika Andreetto et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Uncovering the Mechanism of Aggregation of Human Transthyretin
- (2015) Lorena Saelices et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Targeting protein aggregation for the treatment of degenerative diseases
- (2015) Yvonne S. Eisele et al. NATURE REVIEWS DRUG DISCOVERY
- A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers
- (2015) Samuel I A Cohen et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The role of type 2 diabetes in neurodegeneration
- (2015) Giuseppe Verdile et al. NEUROBIOLOGY OF DISEASE
- Rational design of antibodies targeting specific epitopes within intrinsically disordered proteins
- (2015) Pietro Sormanni et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers
- (2015) Samuel I A Cohen et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Transthyretin-Derived Peptides as β-Amyloid Inhibitors
- (2014) Patricia Y. Cho et al. ACS Chemical Neuroscience
- Rational Design and Identification of a Non-Peptidic Aggregation Inhibitor of Amyloid-β Based on a Pharmacophore Motif Obtained fromcyclo[-Lys-Leu-Val-Phe-Phe-]
- (2014) Tadamasa Arai et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- A β-Hairpin-Binding Protein for Three Different Disease-Related Amyloidogenic Proteins
- (2014) Hamed Shaykhalishahi et al. CHEMBIOCHEM
- The structured core domain of B-crystallin can prevent amyloid fibrillation and associated toxicity
- (2014) G. K. A. Hochberg et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Designed α-sheet peptides inhibit amyloid formation by targeting toxic oligomers
- (2014) Gene Hopping et al. eLife
- Attenuation of the Aggregation and Neurotoxicity of Amyloid-β Peptides by Catalytic Photooxygenation
- (2013) Atsuhiko Taniguchi et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Selectively N-Methylated Soluble IAPP Mimics as Potent IAPP Receptor Agonists and Nanomolar Inhibitors of Cytotoxic Self-Assembly of Both IAPP and Aβ40
- (2013) Li-Mei Yan et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Multifaceted Roles of Disulfide Bonds. Peptides as Therapeutics
- (2013) Miriam Góngora-Benítez et al. CHEMICAL REVIEWS
- Inhibiting and Reversing Amyloid-β Peptide (1-40) Fibril Formation with Gramicidin S and Engineered Analogues
- (2013) Jinghui Luo et al. CHEMISTRY-A EUROPEAN JOURNAL
- In Vitro and Mechanistic Studies of an Antiamyloidogenic Self-Assembled Cyclic d,l-α-Peptide Architecture
- (2013) Michal Richman et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- A Novel Retro-Inverso Peptide Inhibitor Reduces Amyloid Deposition, Oxidation and Inflammation and Stimulates Neurogenesis in the APPswe/PS1ΔE9 Mouse Model of Alzheimer’s Disease
- (2013) Vadivel Parthsarathy et al. PLoS One
- Designed Trpzip-3 β-Hairpin Inhibits Amyloid Formation in Two Different Amyloid Systems
- (2013) Gene Hopping et al. ACS Medicinal Chemistry Letters
- The Future of Peptide-based Drugs
- (2012) David J. Craik et al. Chemical Biology & Drug Design
- A Two-Step Strategy for Structure-Activity Relationship Studies of N-Methylated Aβ42 C-Terminal Fragments as Aβ42 Toxicity Inhibitors
- (2012) Huiyuan Li et al. ChemMedChem
- Peptides for Therapy and Diagnosis of Alzheimer's Disease
- (2012) Susanne Aileen Funke et al. CURRENT PHARMACEUTICAL DESIGN
- Inhibition of Amyloid Formation
- (2012) Torleif Härd et al. JOURNAL OF MOLECULAR BIOLOGY
- Amyloid β-sheet mimics that antagonize protein aggregation and reduce amyloid toxicity
- (2012) Pin-Nan Cheng et al. Nature Chemistry
- The many faces of α-synuclein: from structure and toxicity to therapeutic target
- (2012) Hilal A. Lashuel et al. NATURE REVIEWS NEUROSCIENCE
- Rational design of potent domain antibody inhibitors of amyloid fibril assembly
- (2012) A. R. A. Ladiwala et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The generic amyloid formation inhibition effect of a designed small aromatic β-breaking peptide
- (2011) Anat Frydman-Marom et al. AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS
- Designed Hairpin Peptides Interfere with Amyloidogenesis Pathways: Fibril Formation and Cytotoxicity Inhibition, Interception of the Preamyloid State
- (2011) Kelly N. L. Huggins et al. BIOCHEMISTRY
- Macrocyclic β-Sheet Peptides That Inhibit the Aggregation of a Tau-Protein-Derived Hexapeptide
- (2011) Jing Zheng et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Structure-based design of non-natural amino-acid inhibitors of amyloid fibril formation
- (2011) Stuart A. Sievers et al. NATURE
- Islet Amyloid Polypeptide, Islet Amyloid, and Diabetes Mellitus
- (2011) Per Westermark et al. PHYSIOLOGICAL REVIEWS
- Structure-based design of conformation- and sequence-specific antibodies against amyloid
- (2011) J. M. Perchiacca et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Identification of Hot Regions of the Aβ-IAPP Interaction Interface as High-Affinity Binding Sites in both Cross- and Self-Association
- (2010) Erika Andreetto et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Development of a Proteolytically Stable Retro-Inverso Peptide Inhibitor of β-Amyloid Oligomerization as a Potential Novel Treatment for Alzheimer’s Disease
- (2010) Mark Taylor et al. BIOCHEMISTRY
- Retro-Enantio N-Methylated Peptides as β-Amyloid Aggregation Inhibitors
- (2009) Dolors Grillo-Bosch et al. ChemMedChem
- Atomic structures of IAPP (amylin) fusions suggest a mechanism for fibrillation and the role of insulin in the process
- (2009) Jed J. W. Wiltzius et al. PROTEIN SCIENCE
- N-Methylation of Peptides: A New Perspective in Medicinal Chemistry
- (2008) Jayanta Chatterjee et al. ACCOUNTS OF CHEMICAL RESEARCH
- Exploiting Cross-Amyloid Interactions To Inhibit Protein Aggregation but not Function: Nanomolar Affinity Inhibition of Insulin Aggregation by an IAPP Mimic
- (2008) Aleksandra Velkova et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Cognitive-Performance Recovery of Alzheimer's Disease Model Mice by Modulation of Early Soluble Amyloidal Assemblies
- (2008) Anat Frydman-Marom et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Reduction of Alzheimer’s Disease Amyloid Plaque Load in Transgenic Mice by D3, a D-Enantiomeric Peptide Identified by Mirror Image Phage Display
- (2008) Thomas van Groen et al. ChemMedChem
- Transthyretin protects Alzheimer's mice from the behavioral and biochemical effects of A toxicity
- (2008) J. N. Buxbaum et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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