Targeting Apolipoprotein E/Amyloid β Binding by Peptoid CPO_Aβ17-21 P Ameliorates Alzheimer’s Disease Related Pathology and Cognitive Decline

Apolipoprotein E, Receptors, and Modulation of Alzheimer’s Disease

(2018) Na Zhao et al.   BIOLOGICAL PSYCHIATRY

Apolipoprotein E and Alzheimer’s disease: the influence of apolipoprotein E on amyloid-β and other amyloidogenic proteins

(2017) Tien-Phat V. Huynh et al.   JOURNAL OF LIPID RESEARCH

Innate Immunity Stimulation via Toll-Like Receptor 9 Ameliorates Vascular Amyloid Pathology in Tg-SwDI Mice with Associated Cognitive Benefits

(2017) Henrieta Scholtzova et al.   JOURNAL OF NEUROSCIENCE

Co-injection of Aβ1-40 and ApoE4 impaired spatial memory and hippocampal long-term potentiation in rats

(2017) Meina Wu et al.   NEUROSCIENCE LETTERS

Alzheimer’s disease: experimental models and reality

(2016) Eleanor Drummond et al.   ACTA NEUROPATHOLOGICA

Apolipoprotein E as a Therapeutic Target in Alzheimer’s Disease: A Review of Basic Research and Clinical Evidence

(2016) Yu Yamazaki et al.   CNS DRUGS

Apolipoprotein E metabolism and functions in brain and its role in Alzheimerʼs disease

(2016) Fan Liao et al.   CURRENT OPINION IN LIPIDOLOGY

The amyloid hypothesis of Alzheimer's disease at 25 years

(2016) Dennis J Selkoe et al.   EMBO Molecular Medicine

An Oral Aβ Vaccine Using a Recombinant Adeno-Associated Virus Vector in Aged Monkeys: Reduction in Plaque Amyloid and Increase in Aβ Oligomers

(2016) Hideo Hara et al.   JOURNAL OF ALZHEIMERS DISEASE

Alzheimer's disease

(2016) Philip Scheltens et al.   LANCET

Amyloid β-interacting partners in Alzheimer's disease: From accomplices to possible therapeutic targets

(2016) Sun-Ho Han et al.   PROGRESS IN NEUROBIOLOGY

Chemical Cross-Linking/Mass Spectrometry Maps the Amyloid β Peptide Binding Region on Both Apolipoprotein E Domains

(2015) Stéphanie Deroo et al.   ACS Chemical Biology

Amyloid β oligomers in Alzheimer’s disease pathogenesis, treatment, and diagnosis

(2015) Kirsten L. Viola et al.   ACTA NEUROPATHOLOGICA

An overview of peptide and peptoid foldamers in medicinal chemistry

(2015) István M Mándity et al.   Expert Opinion on Drug Discovery

Facile Solid-Phase Parallel Synthesis of Linear and Cyclic Peptoids for Comparative Studies of Biological Activity

(2015) Shinae Park et al.   ACS Combinatorial Science

The Binding of Apolipoprotein E to Oligomers and Fibrils of Amyloid-β Alters the Kinetics of Amyloid Aggregation

(2014) Kanchan Garai et al.   BIOCHEMISTRY

Apolipoprotein E: Structure and function in lipid metabolism, neurobiology, and Alzheimer's diseases

(2014) Yadong Huang et al.   NEUROBIOLOGY OF DISEASE

Blocking the apoE/Aβ interaction ameliorates Aβ-related pathology in APOE ε2 and ε4 targeted replacement Alzheimer model mice

(2014) Joanna E Pankiewicz et al.   Acta Neuropathologica Communications

Inflammatory components in human Alzheimer’s disease and after active amyloid-β42 immunization

(2013) Elina Zotova et al.   BRAIN

Immunomodulation targeting of both Aβ and tau pathological conformers ameliorates Alzheimer’s disease pathology in TgSwDI and 3xTg mouse models

(2013) Fernando Goñi et al.   Journal of Neuroinflammation

Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy

(2013) Chia-Chen Liu et al.   Nature Reviews Neurology

ApoE influences amyloid-  (A ) clearance despite minimal apoE/A  association in physiological conditions

(2013) P. B. Verghese et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

APOE4-specific Changes in Aβ Accumulation in a New Transgenic Mouse Model of Alzheimer Disease

(2012) Katherine L. Youmans et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Apolipoprotein E, Especially Apolipoprotein E4, Increases the Oligomerization of Amyloid   Peptide

(2012) T. Hashimoto et al.   JOURNAL OF NEUROSCIENCE

Mapping ApoE/Aβ binding regions to guide inhibitor discovery

(2011) Qian Liu et al.   Molecular BioSystems

Ring-Closing Metathesis Approaches for the Solid-Phase Synthesis of Cyclic Peptoids

(2011) Sharaf Nawaz Khan et al.   ORGANIC LETTERS

Human apoE Isoforms Differentially Regulate Brain Amyloid-  Peptide Clearance

(2011) J. M. Castellano et al.   Science Translational Medicine

Efficient Solid-Phase Synthesis of a Series of Cyclic and Linear Peptoid−Dexamethasone Conjugates for the Cell Permeability Studies

(2010) Suekyung Cho et al.   JOURNAL OF COMBINATORIAL CHEMISTRY

Dystrophic (senescent) rather than activated microglial cells are associated with tau pathology and likely precede neurodegeneration in Alzheimer’s disease

(2009) Wolfgang J. Streit et al.   ACTA NEUROPATHOLOGICA

Encoded combinatorial libraries for the construction of cyclic peptoid microarrays

(2008) Yong-Uk Kwon et al.   CHEMICAL COMMUNICATIONS