Secondary nucleation and elongation occur at different sites on Alzheimer’s amyloid-β aggregates
出版年份 2019 全文链接
标题
Secondary nucleation and elongation occur at different sites on Alzheimer’s amyloid-β aggregates
作者
关键词
-
出版物
Science Advances
Volume 5, Issue 4, Pages eaau3112
出版商
American Association for the Advancement of Science (AAAS)
发表日期
2019-04-18
DOI
10.1126/sciadv.aau3112
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Chemical Kinetics for Bridging Molecular Mechanisms and Macroscopic Measurements of Amyloid Fibril Formation
- (2018) Thomas C.T. Michaels et al. Annual Review of Physical Chemistry
- Secondary nucleation in amyloid formation
- (2018) Mattias Törnquist et al. CHEMICAL COMMUNICATIONS
- Loss of clusterin shifts amyloid deposition to the cerebrovasculature via disruption of perivascular drainage pathways
- (2017) Aleksandra M. Wojtas et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Phage display and kinetic selection of antibodies that specifically inhibit amyloid self-replication
- (2017) Anna Munke et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inhibiting the Ca 2+ Influx Induced by Human CSF
- (2017) Anna Drews et al. Cell Reports
- Selective targeting of primary and secondary nucleation pathways in Aβ42 aggregation using a rational antibody scanning method
- (2017) Francesco A. Aprile et al. Science Advances
- Particle-Based Monte-Carlo Simulations of Steady-State Mass Transport at Intermediate Péclet Numbers
- (2016) Thomas Müller et al. INTERNATIONAL JOURNAL OF NONLINEAR SCIENCES AND NUMERICAL SIMULATION
- Clusterin Binds to Aβ1–42Oligomers with High Affinity and Interferes with Peptide Aggregation by Inhibiting Primary and Secondary Nucleation
- (2016) Marten Beeg et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Kinetic analysis reveals the diversity of microscopic mechanisms through which molecular chaperones suppress amyloid formation
- (2016) Paolo Arosio et al. Nature Communications
- Effect of CLU genetic variants on cerebrospinal fluid and neuroimaging markers in healthy, mild cognitive impairment and Alzheimer’s disease cohorts
- (2016) Lin Tan et al. Scientific Reports
- An anticancer drug suppresses the primary nucleation reaction that initiates the production of the toxic A 42 aggregates linked with Alzheimers disease
- (2016) J. Habchi et al. Science Advances
- Microfluidic Diffusion Analysis of the Sizes and Interactions of Proteins under Native Solution Conditions
- (2015) Paolo Arosio et al. ACS Nano
- Latent analysis of unmodified biomolecules and their complexes in solution with attomole detection sensitivity
- (2015) Emma V. Yates et al. Nature Chemistry
- A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers
- (2015) Samuel I A Cohen et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- A molecular chaperone breaks the catalytic cycle that generates toxic Aβ oligomers
- (2015) Samuel I A Cohen et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Interaction of the Molecular Chaperone DNAJB6 with Growing Amyloid-beta 42 (Aβ42) Aggregates Leads to Sub-stoichiometric Inhibition of Amyloid Formation
- (2014) Cecilia Månsson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The amyloid state and its association with protein misfolding diseases
- (2014) Tuomas P. J. Knowles et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Expression and Purification of Chaperone-Active Recombinant Clusterin
- (2014) Rebecca A. Dabbs et al. PLoS One
- Chemical kinetics for drug discovery to combat protein aggregation diseases
- (2014) Paolo Arosio et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Extracellular Chaperones and Proteostasis
- (2013) Amy R. Wyatt et al. Annual Review of Biochemistry
- Quantification of the Concentration of Aβ42 Propagons during the Lag Phase by an Amyloid Chain Reaction Assay
- (2013) Paolo Arosio et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Proliferation of amyloid- 42 aggregates occurs through a secondary nucleation mechanism
- (2013) S. I. A. Cohen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Amyloid State of Proteins in Human Diseases
- (2012) David Eisenberg et al. CELL
- BRICHOS Domains Efficiently Delay Fibrillation of Amyloid β-Peptide
- (2012) Hanna Willander et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes
- (2012) Iryna Benilova et al. NATURE NEUROSCIENCE
- Nucleated polymerization with secondary pathways. II. Determination of self-consistent solutions to growth processes described by non-linear master equations
- (2011) Samuel I. A. Cohen et al. JOURNAL OF CHEMICAL PHYSICS
- Nucleated polymerization with secondary pathways. I. Time evolution of the principal moments
- (2011) Samuel I. A. Cohen et al. JOURNAL OF CHEMICAL PHYSICS
- Molecular chaperones in protein folding and proteostasis
- (2011) F. Ulrich Hartl et al. NATURE
- The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics
- (2011) Eric Karran et al. NATURE REVIEWS DRUG DISCOVERY
- The extracellular chaperone clusterin sequesters oligomeric forms of the amyloid-β1−40 peptide
- (2011) Priyanka Narayan et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Extracellular chaperones modulate the effects of Alzheimer’s patient cerebrospinal fluid on Aβ1-42 toxicity and uptake
- (2009) Justin J. Yerbury et al. CELL STRESS & CHAPERONES
- An Analytical Solution to the Kinetics of Breakable Filament Assembly
- (2009) T. P. J. Knowles et al. SCIENCE
- α2-Macroglobulin and Haptoglobin Suppress Amyloid Formation by Interacting with Prefibrillar Protein Species
- (2008) Justin J. Yerbury et al. JOURNAL OF BIOLOGICAL CHEMISTRY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now