T-Cell Receptor Cognate Target Prediction Based on Paired α and β Chain Sequence and Structural CDR Loop Similarities

Identification of the cognate peptide-MHC target of T cell receptors using molecular modeling and force field scoring

(2018) Esteban Lanzarotti et al.   MOLECULAR IMMUNOLOGY

TCRmodel: high resolution modeling of T cell receptors from sequence

(2018) Ragul Gowthaman et al.   NUCLEIC ACIDS RESEARCH

Changes in the TCRβ Repertoire and Tumor Immune Signature From a Cutaneous Melanoma Patient Immunized With the CSF-470 Vaccine: A Case Report

(2018) Mariana Aris et al.   Frontiers in Immunology

A cancer vaccine approach for personalized treatment of Lynch Syndrome

(2018) Snigdha Majumder et al.   Scientific Reports

Exploring the pre-immune landscape of antigen-specific T cells

(2018) Mikhail V. Pogorelyy et al.   Genome Medicine

Predicting CD4 T-cell epitopes based on antigen cleavage, MHCII presentation, and TCR recognition

(2018) Dina Schneidman-Duhovny et al.   PLoS One

Unbiased Identification of T-Cell Receptors Targeting Immunodominant Peptide–MHC Complexes for T-Cell Receptor Immunotherapy

(2017) Felix K.M. Lorenz et al.   HUMAN GENE THERAPY

On the feasibility of mining CD8+ T cell receptor patterns underlying immunogenic peptide recognition

(2017) Nicolas De Neuter et al.   IMMUNOGENETICS

Comparative analysis of murine T-cell receptor repertoires

(2017) Mark Izraelson et al.   IMMUNOLOGY

Emerging Concepts in TCR Specificity: Rationalizing and (Maybe) Predicting Outcomes

(2017) Nishant K. Singh et al.   JOURNAL OF IMMUNOLOGY

Quantifiable predictive features define epitope-specific T cell receptor repertoires

(2017) Pradyot Dash et al.   NATURE

Identifying specificity groups in the T cell receptor repertoire

(2017) Jacob Glanville et al.   NATURE

Immunosequencing identifies signatures of cytomegalovirus exposure history and HLA-mediated effects on the T cell repertoire

(2017) Ryan O Emerson et al.   NATURE GENETICS

VDJdb: a curated database of T-cell receptor sequences with known antigen specificity

(2017) Mikhail Shugay et al.   NUCLEIC ACIDS RESEARCH

DynaDom: structure-based prediction of T cell receptor inter-domain and T cell receptor-peptide-MHC (class I) association angles

(2017) Thomas Hoffmann et al.   BMC STRUCTURAL BIOLOGY

T cell receptor repertoires of mice and humans are clustered in similarity networks around conserved public CDR3 sequences

(2017) Asaf Madi et al.   eLife

Discovery of immunodominant T-cell epitopes reveals penton protein as a second immunodominant target in human adenovirus infection

(2016) Sabine Tischer et al.   Journal of Translational Medicine

T cell fate and clonality inference from single-cell transcriptomes

(2016) Michael J T Stubbington et al.   NATURE METHODS

Human CD8+T Cells Target Multiple Epitopes in Respiratory Syncytial Virus Polymerase

(2016) Daniel Burbulla et al.   VIRAL IMMUNOLOGY

T Cell Antigen Receptor Recognition of Antigen-Presenting Molecules

(2015) Jamie Rossjohn et al.   Annual Review of Immunology

Identification of a Novel Immunodominant HLA-B*07

(2015) Patrick S. Günther et al.   JOURNAL OF IMMUNOTHERAPY

Improved structural method for T-cell cross-reactivity prediction

(2015) Marcus F.A. Mendes et al.   MOLECULAR IMMUNOLOGY

LYRA, a webserver for lymphocyte receptor structural modeling

(2015) Michael Schantz Klausen et al.   NUCLEIC ACIDS RESEARCH

High-throughput pairing of T cell receptor α and β sequences

(2015) Bryan Howie et al.   Science Translational Medicine

A bioinformatic framework for immune repertoire diversity profiling enables detection of immunological status

(2015) Victor Greiff et al.   Genome Medicine

Deconstructing the Peptide-MHC Specificity of T Cell Recognition

(2014) Michael E. Birnbaum et al.   CELL

Understanding the structural dynamics of TCR-pMHC interactions

(2014) Itamar Kass et al.   TRENDS IN IMMUNOLOGY

Studying the antibody repertoire after vaccination: practical applications

(2014) Jacob D. Galson et al.   TRENDS IN IMMUNOLOGY

Immune Activation and a 9-Year Ongoing Complete Remission Following CD40 Antibody Therapy and Metastasectomy in a Patient with Metastatic Melanoma

(2014) D. L. Bajor et al.   Cancer Immunology Research

TCR Repertoire Analysis by Next Generation Sequencing Allows Complex Differential Diagnosis of T Cell-Related Pathology

(2013) M. Dziubianau et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Genome-wide structural modelling of TCR-pMHC interactions

(2013) I-Hsin Liu et al.   BMC GENOMICS

Pairing of T-cell receptor chains via emulsion PCR

(2013) Maria A. Turchaninova et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Introduction to the Peptide Binding Problem of Computational Immunology: New Results

(2013) Wen-Jun Shen et al.   FOUNDATIONS OF COMPUTATIONAL MATHEMATICS

High-throughput sequencing of the paired human immunoglobulin heavy and light chain repertoire

(2013) Brandon J DeKosky et al.   NATURE BIOTECHNOLOGY

Structure-Based, Rational Design of T Cell Receptors

(2013) V. Zoete et al.   Frontiers in Immunology

Analysis of the Paired TCR α- and β-chains of Single Human T Cells

(2012) Song-Min Kim et al.   PLoS One

Rep-Seq: uncovering the immunological repertoire through next-generation sequencing

(2011) Jennifer Benichou et al.   IMMUNOLOGY

TCRep 3D: An Automated In Silico Approach to Study the Structural Properties of TCR Repertoires

(2011) Antoine Leimgruber et al.   PLoS One

Paired analysis of TCRα and TCRβ chains at the single-cell level in mice

(2010) Pradyot Dash et al.   JOURNAL OF CLINICAL INVESTIGATION