Exploring the pre-immune landscape of antigen-specific T cells

High-throughput immune repertoire analysis with IGoR

(2018) Quentin Marcou et al.   Nature Communications

Method for identification of condition-associated public antigen receptor sequences

(2018) Mikhail V Pogorelyy et al.   eLife

Quantifiable predictive features define epitope-specific T cell receptor repertoires

(2017) Pradyot Dash et al.   NATURE

Identifying specificity groups in the T cell receptor repertoire

(2017) Jacob Glanville et al.   NATURE

Immunosequencing identifies signatures of cytomegalovirus exposure history and HLA-mediated effects on the T cell repertoire

(2017) Ryan O Emerson et al.   NATURE GENETICS

VDJdb: a curated database of T-cell receptor sequences with known antigen specificity

(2017) Mikhail Shugay et al.   NUCLEIC ACIDS RESEARCH

Persisting fetal clonotypes influence the structure and overlap of adult human T cell receptor repertoires

(2017) Mikhail V. Pogorelyy et al.   PLoS Computational Biology

Discovery of T Cell Receptor β Motifs Specific to HLA-B27-Positive Ankylosing Spondylitis by Deep Repertoire Sequence Analysis

(2017) Malek Faham et al.   Arthritis & Rheumatology

The Immune Epitope Database and Analysis Resource in Epitope Discovery and Synthetic Vaccine Design

(2017) Ward Fleri et al.   Frontiers in Immunology

Toward a Rapid Production of Multivirus-Specific T Cells Targeting BKV, Adenovirus, CMV, and EBV from Umbilical Cord Blood

(2017) Hema Dave et al.   Molecular Therapy-Methods & Clinical Development

VDJviz: a versatile browser for immunogenomics data

(2016) Dmitriy V. Bagaev et al.   BMC GENOMICS

Genetic Ancestry and Natural Selection Drive Population Differences in Immune Responses to Pathogens

(2016) Yohann Nédélec et al.   CELL

Genetic Adaptation and Neandertal Admixture Shaped the Immune System of Human Populations

(2016) Hélène Quach et al.   CELL

Linking the T cell receptor to the single cell transcriptome in antigen-specific human T cells

(2016) Auda A Eltahla et al.   IMMUNOLOGY AND CELL BIOLOGY

Dynamics of Individual T Cell Repertoires: From Cord Blood to Centenarians

(2016) Olga V. Britanova et al.   JOURNAL OF IMMUNOLOGY

Computational genomics tools for dissecting tumour–immune cell interactions

(2016) Hubert Hackl et al.   NATURE REVIEWS GENETICS

Targeting of cancer neoantigens with donor-derived T cell receptor repertoires

(2016) E. Stronen et al.   SCIENCE

Cross-Reactivity of TCR Repertoire: Current Concepts, Challenges, and Implication for Allotransplantation

(2016) Nicolas Degauque et al.   Frontiers in Immunology

T Cell Antigen Receptor Recognition of Antigen-Presenting Molecules

(2015) Jamie Rossjohn et al.   Annual Review of Immunology

αβ T cell receptors as predictors of health and disease

(2015) Meriem Attaf et al.   Cellular & Molecular Immunology

Naive CD8+ T-cell precursors display structured TCR repertoires and composite antigen-driven selection dynamics

(2015) Michelle A Neller et al.   IMMUNOLOGY AND CELL BIOLOGY

MiXCR: software for comprehensive adaptive immunity profiling

(2015) Dmitriy A Bolotin et al.   NATURE METHODS

How a well-adapted immune system is organized

(2015) Andreas Mayer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TCR contact residue hydrophobicity is a hallmark of immunogenic CD8+T cell epitopes

(2015) Diego Chowell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-throughput pairing of T cell receptor α and β sequences

(2015) Bryan Howie et al.   Science Translational Medicine

Bioinformatic and Statistical Analysis of Adaptive Immune Repertoires

(2015) Victor Greiff et al.   TRENDS IN IMMUNOLOGY

VDJtools: Unifying Post-analysis of T Cell Receptor Repertoires

(2015) Mikhail Shugay et al.   PLoS Computational Biology

Contribution of TCR-  Locus and HLA to the Shape of the Mature Human V  Repertoire

(2014) J. J. Melenhorst et al.   JOURNAL OF IMMUNOLOGY

Quantification of HTLV-1 Clonality and TCR Diversity

(2014) Daniel J. Laydon et al.   PLoS Computational Biology

Theories and Quantification of Thymic Selection

(2014) Andrew J. Yates   Frontiers in Immunology

Race and sex-based differences in cytokine immune responses to smallpox vaccine in healthy individuals

(2013) Iana H. Haralambieva et al.   HUMAN IMMUNOLOGY

Age-Specific Prevalence of Epstein–Barr Virus Infection Among Individuals Aged 6–19 Years in the United States and Factors Affecting Its Acquisition

(2013) Henry H. Balfour et al.   JOURNAL OF INFECTIOUS DISEASES

Properties of MHC Class I Presented Peptides That Enhance Immunogenicity

(2013) Jorg J. A. Calis et al.   PLoS Computational Biology

Huge Overlap of Individual TCR Beta Repertoires

(2013) Mikhail Shugay et al.   Frontiers in Immunology

Peptide length determines the outcome of TCR/peptide-MHCI engagement

(2012) J. Ekeruche-Makinde et al.   BLOOD

The Role of Naive T Cell Precursor Frequency and Recruitment in Dictating Immune Response Magnitude

(2012) M. K. Jenkins et al.   JOURNAL OF IMMUNOLOGY

Statistical inference of the generation probability of T-cell receptors from sequence repertoires

(2012) A. Murugan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rep-Seq: uncovering the immunological repertoire through next-generation sequencing

(2011) Jennifer Benichou et al.   IMMUNOLOGY

Enumeration of human antigen-specific naive CD8+ T cells reveals conserved precursor frequencies

(2010) C. Alanio et al.   BLOOD

Germ Line-governed Recognition of a Cancer Epitope by an Immunodominant Human T-cell Receptor

(2009) David K. Cole et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endogenous Naive CD8+ T Cell Precursor Frequency Regulates Primary and Memory Responses to Infection

(2008) Joshua J. Obar et al.   IMMUNITY

Host Ethnicity and Virus Genotype Shape the Hepatitis B Virus-Specific T-Cell Repertoire

(2008) A. T. Tan et al.   JOURNAL OF VIROLOGY

IMGT(R), the international ImMunoGeneTics information system(R)

(2008) M.-P. Lefranc et al.   NUCLEIC ACIDS RESEARCH