Novel Cellular Functions of Very Long Chain-Fatty Acids: Insight From ELOVL4 Mutations
出版年份 2019 全文链接
标题
Novel Cellular Functions of Very Long Chain-Fatty Acids: Insight From ELOVL4 Mutations
作者
关键词
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出版物
Frontiers in Cellular Neuroscience
Volume 13, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2019-09-20
DOI
10.3389/fncel.2019.00428
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Decreased very long chain polyunsaturated fatty acids in sperm correlates with sperm quantity and quality
- (2019) LaTasha B. Craig et al. JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
- Prevalence and clinicoradiological features of spinocerebellar ataxia type 34 in a Japanese ataxia cohort
- (2019) Kokoro Ozaki et al. PARKINSONISM & RELATED DISORDERS
- Very long-chain tear film lipids produced by fatty acid elongase ELOVL1 prevent dry eye disease in mice
- (2018) Takayuki Sassa et al. FASEB JOURNAL
- Cloning, tissue distribution, functional characterization and nutritional regulation of a fatty acyl Elovl5 elongase in chu's croaker Nibea coibor
- (2018) Zhideng Lin et al. GENE
- Differential Composition of DHA and Very Long Chain PUFAs in Rod and Cone Photoreceptors
- (2018) Martin-Paul G. Agbaga et al. JOURNAL OF LIPID RESEARCH
- Elovl4andFa2hexpression during rat spermatogenesis: a link to the very-long-chain PUFAs typical of germ cell sphingolipids
- (2018) Florencia X. Santiago Valtierra et al. JOURNAL OF LIPID RESEARCH
- Ca2+ and lipid signals hold hands at endoplasmic reticulum-plasma membrane contact sites
- (2018) Tamas Balla JOURNAL OF PHYSIOLOGY-LONDON
- “Lipid raft aging” in the human frontal cortex during nonpathological aging: gender influences and potential implications in Alzheimer's disease
- (2018) Mario Díaz et al. NEUROBIOLOGY OF AGING
- Age-related DNA methylation changes are tissue-specific with ELOVL2 promoter methylation as exception
- (2018) Roderick C. Slieker et al. Epigenetics & Chromatin
- FADS1-FADS2 and ELOVL2 gene polymorphisms in susceptibility to autism spectrum disorders in Chinese children
- (2018) Caihong Sun et al. BMC Psychiatry
- The Role of Lipids and Membranes in the Pathogenesis of Alzheimer's Disease: A Comprehensive View
- (2018) Botond Penke et al. Current Alzheimer Research
- DNA methylation of the ELOVL2, FHL2, KLF14, C1orf132/MIR29B2C, and TRIM59 genes for age prediction from blood, saliva, and buccal swab samples
- (2018) Sang-Eun Jung et al. Forensic Science International-Genetics
- PI3K Signaling in Neurons: A Central Node for the Control of Multiple Functions
- (2018) Karina Sánchez-Alegría et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- De novo mutation in ELOVL1 causes ichthyosis, acanthosis nigricans, hypomyelination, spastic paraplegia, high frequency deafness and optic atrophy
- (2018) Noomi Mueller et al. JOURNAL OF MEDICAL GENETICS
- Docosanoids and elovanoids from omega-3 fatty acids are pro-homeostatic modulators of inflammatory responses, cell damage and neuroprotection
- (2018) Nicolas G. Bazan MOLECULAR ASPECTS OF MEDICINE
- ELOVL4: Very long-chain fatty acids serve an eclectic role in mammalian health and function
- (2018) Blake R. Hopiavuori et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Association of GALC, ZNF184, IL1R2 and ELOVL7 With Parkinson’s Disease in Southern Chinese
- (2018) Gen Li et al. Frontiers in Aging Neuroscience
- Trends in DNA Methylation with Age Replicate Across Diverse Human Populations
- (2017) Shyamalika Gopalan et al. GENETICS
- DNA methylation in ELOVL2 and C1orf132 correctly predicted chronological age of individuals from three disease groups
- (2017) M. Spólnicka et al. INTERNATIONAL JOURNAL OF LEGAL MEDICINE
- Regional changes in CNS and retinal glycerophospholipid profiles with age: a molecular blueprint
- (2017) Blake R. Hopiavuori et al. JOURNAL OF LIPID RESEARCH
- Cross-sectional associations of cortical β-amyloid with erythrocyte membrane long-chain polyunsaturated fatty acids in older adults with subjective memory complaints
- (2017) Claudie Hooper et al. JOURNAL OF NEUROCHEMISTRY
- Homozygous Expression of Mutant ELOVL4 Leads to Seizures and Death in a Novel Animal Model of Very Long-Chain Fatty Acid Deficiency
- (2017) Blake R. Hopiavuori et al. MOLECULAR NEUROBIOLOGY
- Effect of omega-3 fatty acids on cognition: an updated systematic review of randomized clinical trials
- (2017) Oscar D Rangel-Huerta et al. NUTRITION REVIEWS
- Motor Deficits and Cerebellar Atrophy in Elovl5 Knock Out Mice
- (2017) Eriola Hoxha et al. Frontiers in Cellular Neuroscience
- Distribution of ELOVL4 in the Developing and Adult Mouse Brain
- (2017) David M. Sherry et al. Frontiers in Neuroanatomy
- Trends in DNA Methylation with Age Replicate Across Diverse Human Populations
- (2017) Shyamalika Gopalan et al. GENETICS
- Elovanoids are a novel class of homeostatic lipid mediators that protect neural cell integrity upon injury
- (2017) Surjyadipta Bhattacharjee et al. Science Advances
- Changes in lipid membranes may trigger amyloid toxicity in Alzheimer's disease
- (2017) Elizabeth Drolle et al. PLoS One
- Elovanoids are novel cell-specific lipid mediators necessary for neuroprotective signaling for photoreceptor cell integrity
- (2017) Bokkyoo Jun et al. Scientific Reports
- To treat or not to treat drug-refractory epilepsy by the ketogenic diet? That is the question
- (2016) Marzena Ułamek-Kozioł et al. ANNALS OF AGRICULTURAL AND ENVIRONMENTAL MEDICINE
- Biosynthesis of long-chain polyunsaturated fatty acids in the African catfish Clarias gariepinus: Molecular cloning and functional characterisation of fatty acyl desaturase (fads2) and elongase (elovl2) cDNAs7
- (2016) Angela Oboh et al. AQUACULTURE
- Analysis of ELOVL4 and PRPH2 genes in Turkish Stargardt disease patients
- (2016) H. Bardak et al. GENETICS AND MOLECULAR RESEARCH
- Associations between Serum Omega-3 Fatty Acid Levels and Cognitive Functions among Community-Dwelling Octogenarians in Okinawa, Japan: The KOCOA Study
- (2016) Junko Nishihira et al. JOURNAL OF ALZHEIMERS DISEASE
- Membrane Lipids in Presynaptic Function and Disease
- (2016) Elsa Lauwers et al. NEURON
- Crucial Role of Elovl6 in Chondrocyte Growth and Differentiation during Growth Plate Development in Mice
- (2016) Manami Kikuchi et al. PLoS One
- Ectopic expression of ceramide synthase 2 in neurons suppresses neurodegeneration induced by ceramide synthase 1 deficiency
- (2016) Stefka D. Spassieva et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Long-chain polyunsaturated fatty acid biosynthesis in chordates: Insights into the evolution of Fads and Elovl gene repertoire
- (2016) L. Filipe C. Castro et al. PROGRESS IN LIPID RESEARCH
- Intakes of fish and polyunsaturated fatty acids and mild-to-severe cognitive impairment risks: a dose-response meta-analysis of 21 cohort studies1–3
- (2015) Yu Zhang et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Brain membrane lipids in major depression and anxiety disorders
- (2015) Christian P. Müller et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Phosphatidylserine-Dependent Catalysis of Stalk and Pore Formation by Synaptobrevin JMR-TMD Peptide
- (2015) Pradip K. Tarafdar et al. BIOPHYSICAL JOURNAL
- Male meiotic cytokinesis requires ceramide synthase 3-dependent sphingolipids with unique membrane anchors
- (2015) Mariona Rabionet et al. HUMAN MOLECULAR GENETICS
- No Effect of Omega-3 Fatty Acid Supplementation on Cognition and Mood in Individuals with Cognitive Impairment and Probable Alzheimer’s Disease: A Randomised Controlled Trial
- (2015) Michelle Phillips et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Organization and Evolution of Brain Lipidome Revealed by Large-Scale Analysis of Human, Chimpanzee, Macaque, and Mouse Tissues
- (2015) Katarzyna Bozek et al. NEURON
- Phosphoinositide regulation of TRPV1 revisited
- (2015) Tibor Rohacs PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- From zero to six double bonds: phospholipid unsaturation and organelle function
- (2015) Bruno Antonny et al. TRENDS IN CELL BIOLOGY
- Autophagy in synaptic development, function, and pathology
- (2015) Dan-Na Shen et al. Neuroscience Bulletin
- Brown Adipose Tissue Thermogenic Capacity Is Regulated by Elovl6
- (2015) Chong Yew Tan et al. Cell Reports
- A NewELOVL4Mutation in a Case of Spinocerebellar Ataxia With Erythrokeratodermia
- (2015) Cynthia V. Bourassa et al. JAMA Neurology
- A Novel Mutation inELOVL4Leading to Spinocerebellar Ataxia (SCA) With the Hot Cross Bun Sign but Lacking Erythrokeratodermia
- (2015) Kokoro Ozaki et al. JAMA Neurology
- Effect of n−3 PUFA supplementation on cognitive function throughout the life span from infancy to old age: a systematic review and meta-analysis of randomized controlled trials
- (2014) Jingjing Jiao et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- ELOVL5 Mutations Cause Spinocerebellar Ataxia 38
- (2014) Eleonora Di Gregorio et al. AMERICAN JOURNAL OF HUMAN GENETICS
- A novel recessive mutation in the gene ELOVL4 causes a neuro-ichthyotic disorder with variable expressivity
- (2014) Hina Mir et al. BMC Medical Genetics
- Deletion of ELOVL6 blocks the synthesis of oleic acid but does not prevent the development of fatty liver or insulin resistance
- (2014) Young-Ah Moon et al. JOURNAL OF LIPID RESEARCH
- Endoplasmic reticulum microenvironment and conserved histidines govern ELOVL4 fatty acid elongase activity
- (2014) Sreemathi Logan et al. JOURNAL OF LIPID RESEARCH
- Elovl2 ablation demonstrates that systemic DHA is endogenously produced and is essential for lipid homeostasis in mice
- (2014) Anna M. Pauter et al. JOURNAL OF LIPID RESEARCH
- Polyunsaturated fatty acids and their metabolites in brain function and disease
- (2014) Richard P. Bazinet et al. NATURE REVIEWS NEUROSCIENCE
- Membrane Lipids Tune Synaptic Transmission by Direct Modulation of Presynaptic Potassium Channels
- (2014) Mario Carta et al. NEURON
- The Morphological and Molecular Nature of Synaptic Vesicle Priming at Presynaptic Active Zones
- (2014) Cordelia Imig et al. NEURON
- Expanding the Clinical Phenotype Associated WithELOVL4Mutation
- (2014) Maxime Cadieux-Dion et al. JAMA Neurology
- Differentiation of epidermal keratinocytes is dependent on glucosylceramide:ceramide processing
- (2013) Nicole Amen et al. HUMAN MOLECULAR GENETICS
- Worldwide Dietary Therapies for Adults With Epilepsy and Other Disorders
- (2013) Mackenzie C. Cervenka et al. JOURNAL OF CHILD NEUROLOGY
- Current evidence for the clinical use of long-chain polyunsaturated N-3 fatty acids to prevent age-related cognitive decline and Alzheimer’s disease
- (2013) P. A. Dacks et al. Journal of Nutrition Health & Aging
- Impaired Epidermal Permeability Barrier in Mice Lacking Elovl1, the Gene Responsible for Very-Long-Chain Fatty Acid Production
- (2013) T. Sassa et al. MOLECULAR AND CELLULAR BIOLOGY
- Synaptic PI(3,4,5)P3 Is Required for Syntaxin1A Clustering and Neurotransmitter Release
- (2013) Thang Manh Khuong et al. NEURON
- Ketogenic Diet Efficacy in the Treatment of Intractable Epileptic Spasms
- (2013) Husam R. Kayyali et al. PEDIATRIC NEUROLOGY
- Deciphering mutant ELOVL4 activity in autosomal-dominant Stargardt macular dystrophy
- (2013) S. Logan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Methylation ofELOVL2gene as a new epigenetic marker of age
- (2012) Paolo Garagnani et al. AGING CELL
- Impaired neurotransmission in ether lipid-deficient nerve terminals
- (2012) Alexander Brodde et al. HUMAN MOLECULAR GENETICS
- Very long-chain fatty acids: elongation, physiology and related disorders
- (2012) A. Kihara JOURNAL OF BIOCHEMISTRY
- Cholesterol as a key player in the balance of evoked and spontaneous glutamate release in rat brain cortical synaptosomes
- (2012) Graziele Teixeira et al. NEUROCHEMISTRY INTERNATIONAL
- Lipid rafts, synaptic transmission and plasticity: Impact in age-related neurodegenerative diseases
- (2012) Ana M. Sebastião et al. NEUROPHARMACOLOGY
- Recessive Mutations in ELOVL4 Cause Ichthyosis, Intellectual Disability, and Spastic Quadriplegia
- (2011) Mohammed A. Aldahmesh et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Biosynthesis of very long-chain fatty acids (C>24) in Atlantic salmon: Cloning, functional characterisation, and tissue distribution of an Elovl4 elongase
- (2011) Greta Carmona-Antoñanzas et al. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
- Omega-3 Polyunsaturated Fatty Acids in Alzheimers Disease: Key Questions and Partial Answers
- (2011) F. Calon Current Alzheimer Research
- Biochemical characterization of the very long-chain fatty acid elongase ELOVL7
- (2011) Tatsuro Naganuma et al. FEBS LETTERS
- ELOVL4 protein preferentially elongates 20:5n3 to very long chain PUFAs over 20:4n6 and 22:6n3
- (2011) Man Yu et al. JOURNAL OF LIPID RESEARCH
- Synaptic Vesicle Exocytosis
- (2011) T. C. Sudhof et al. Cold Spring Harbor Perspectives in Biology
- Biosynthesis of long-chain polyunsaturated fatty acids in marine fish: Characterization of an Elovl4-like elongase from cobia Rachycentron canadum and activation of the pathway during early life stages
- (2010) Óscar Monroig et al. AQUACULTURE
- Expression and role of Elovl4 elongases in biosynthesis of very long-chain fatty acids during zebrafish Danio rerio early embryonic development
- (2010) Óscar Monroig et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Characterization of HACD1 K64Q mutant found in arrhythmogenic right ventricular dysplasia patients
- (2010) H. Konishi et al. JOURNAL OF BIOCHEMISTRY
- Cholesterol reduction impairs exocytosis of synaptic vesicles
- (2010) A. Linetti et al. JOURNAL OF CELL SCIENCE
- Retinal very long-chain PUFAs: new insights from studies on ELOVL4 protein
- (2010) Martin-Paul Agbaga et al. JOURNAL OF LIPID RESEARCH
- ELOVL2 controls the level of n-6 28:5 and 30:5 fatty acids in testis, a prerequisite for male fertility and sperm maturation in mice
- (2010) Damir Zadravec et al. JOURNAL OF LIPID RESEARCH
- ELOVL1 production of C24 acyl-CoAs is linked to C24 sphingolipid synthesis
- (2010) Y. Ohno et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Defective lipid transport and biosynthesis in recessive and dominant Stargardt macular degeneration
- (2010) Robert S. Molday et al. PROGRESS IN LIPID RESEARCH
- Oiling the Brain: A Review of Randomized Controlled Trials of Omega-3 Fatty Acids in Psychopathology across the Lifespan
- (2010) Natalie Sinn et al. Nutrients
- PUFA for Prevention and Treatment of Dementia?
- (2009) Carrie I. et al. CURRENT PHARMACEUTICAL DESIGN
- Contiguous gene deletion of ELOVL7, ERCC8 and NDUFAF2 in a patient with a fatal multisystem disorder
- (2009) R. J.R.J. Janssen et al. HUMAN MOLECULAR GENETICS
- Munc18-1 binding to the neuronal SNARE complex controls synaptic vesicle priming
- (2009) Ferenc Deák et al. JOURNAL OF CELL BIOLOGY
- Highly Unsaturated Fatty Acid Synthesis in Atlantic Salmon: Characterization of ELOVL5- and ELOVL2-like Elongases
- (2009) Sofia Morais et al. MARINE BIOTECHNOLOGY
- The key roles of elongases and desaturases in mammalian fatty acid metabolism: Insights from transgenic mice
- (2009) Hervé Guillou et al. PROGRESS IN LIPID RESEARCH
- Membrane Fusion: Grappling with SNARE and SM Proteins
- (2009) T. C. Sudhof et al. SCIENCE
- Medium-chain triglyceride (MCT) ketogenic therapy
- (2008) Yeou-mei Christiana Liu EPILEPSIA
- Male Germ Cells Require Polyenoic Sphingolipids with Complex Glycosylation for Completion of Meiosis
- (2008) Mariona Rabionet et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Role of Stargardt-3 macular dystrophy protein (ELOVL4) in the biosynthesis of very long chain fatty acids
- (2008) M.-P. Agbaga et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Polyunsaturated Fatty Acids Influence Synaptojanin Localization to Regulate Synaptic Vesicle Recycling
- (2007) Esther Marza et al. MOLECULAR BIOLOGY OF THE CELL
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