Partners in Mischief: Functional Networks of Heat Shock Proteins of Plasmodium falciparum and Their Influence on Parasite Virulence
出版年份 2019 全文链接
标题
Partners in Mischief: Functional Networks of Heat Shock Proteins of Plasmodium falciparum and Their Influence on Parasite Virulence
作者
关键词
-
出版物
Biomolecules
Volume 9, Issue 7, Pages 295
出版商
MDPI AG
发表日期
2019-07-23
DOI
10.3390/biom9070295
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Uncoupling the Threading and Unfoldase Actions of Plasmodium HSP101 Reveals Differences in Export between Soluble and Insoluble Proteins
- (2019) Kathryn M. Matthews et al. mBio
- Identification of Hsp90 Inhibitors with Anti -Plasmodium Activity
- (2018) Dora Posfai et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Global analysis of Plasmodium falciparum histidine-rich protein-2 ( pfhrp2 ) and pfhrp3 gene deletions using whole-genome sequencing data and meta-analysis
- (2018) Nuno Sepúlveda et al. INFECTION GENETICS AND EVOLUTION
- Error-prone protein synthesis in parasites with the smallest eukaryotic genome
- (2018) Sergey V. Melnikov et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Uncovering the essential genes of the human malaria parasitePlasmodium falciparumby saturation mutagenesis
- (2018) Min Zhang et al. SCIENCE
- Oxidative stress and protein damage responses mediate artemisinin resistance in malaria parasites
- (2018) Frances Rocamora et al. PLoS Pathogens
- Structural and biochemical characterization of Plasmodium falciparum Hsp70-x reveals functional versatility of its C-terminal EEVN motif
- (2018) Blessing Mabate et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- Discovering Putative Prion-Like Proteins in Plasmodium falciparum: A Computational and Experimental Analysis
- (2018) Irantzu Pallarès et al. Frontiers in Microbiology
- Targeting Heat Shock Proteins in Cancer: A Promising Therapeutic Approach
- (2017) et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Plasmodium Hsp40 and human Hsp70: A potential cochaperone-chaperone complex
- (2017) Payal Jha et al. MOLECULAR AND BIOCHEMICAL PARASITOLOGY
- Extracts Obtained from Pterocarpus angolensis DC and Ziziphus mucronata Exhibit Antiplasmodial Activity and Inhibit Heat Shock Protein 70 (Hsp70) Function
- (2017) Tawanda Zininga et al. MOLECULES
- (−)-Epigallocatechin-3-Gallate Inhibits the Chaperone Activity of Plasmodium falciparum Hsp70 Chaperones and Abrogates Their Association with Functional Partners
- (2017) Tawanda Zininga et al. MOLECULES
- The influence of related and unrelated co-infections on parasite dynamics and virulence
- (2017) A. M. Gleichsner et al. OECOLOGIA
- The exported chaperone Hsp70-x supports virulence functions for Plasmodium falciparum blood stage parasites
- (2017) Sarah C. Charnaud et al. PLoS One
- The Exported Chaperone PfHsp70x Is Dispensable for the Plasmodium falciparum Intraerythrocytic Life Cycle
- (2017) David W. Cobb et al. mSphere
- Proteomic analysis of exported chaperone/co-chaperone complexes of P. falciparum reveals an array of complex protein-protein interactions
- (2017) Qi Zhang et al. Scientific Reports
- Plasmodium falciparum Hsp70-z, an Hsp110 homologue, exhibits independent chaperone activity and interacts with Hsp70-1 in a nucleotide-dependent fashion
- (2016) Tawanda Zininga et al. CELL STRESS & CHAPERONES
- Plasmodium actin is incompletely folded by heterologous protein-folding machinery and likely requires the native Plasmodium chaperonin complex to enter a mature functional state
- (2016) Maya A. Olshina et al. FASEB JOURNAL
- Inhibition of Plasmodium falciparum Hsp90 Contributes to the Antimalarial Activities of Aminoalcohol-carbazoles
- (2016) Tai Wang et al. JOURNAL OF MEDICINAL CHEMISTRY
- The Malarial Exported PFA0660w Is an Hsp40 Co-Chaperone of PfHsp70-x
- (2016) Michael O. Daniyan et al. PLoS One
- Prevalence of pfhrp2 and/or pfhrp3 Gene Deletion in Plasmodium falciparum Population in Eight Highly Endemic States in India
- (2016) Praveen Kumar Bharti et al. PLoS One
- Use of a Chimeric Hsp70 to Enhance the Quality of Recombinant Plasmodium falciparum S-Adenosylmethionine Decarboxylase Protein Produced in Escherichia coli
- (2016) Xolani Henry Makhoba et al. PLoS One
- Artemisinin activity-based probes identify multiple molecular targets within the asexual stage of the malaria parasitesPlasmodium falciparum3D7
- (2016) Hanafy M. Ismail et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A broad analysis of resistance development in the malaria parasite
- (2016) Victoria C. Corey et al. Nature Communications
- Imidazopyridazine Inhibitors of Plasmodium falciparum Calcium-Dependent Protein Kinase 1 Also Target Cyclic GMP-Dependent Protein Kinase and Heat Shock Protein 90 To Kill the Parasite at Different Stages of Intracellular Development
- (2015) Judith L. Green et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Host Erythrocyte Environment Influences the Localization of Exported Protein 2, an Essential Component of the Plasmodium Translocon
- (2015) Elamaran Meibalan et al. EUKARYOTIC CELL
- PFB0595w is a Plasmodium falciparum J protein that co-localizes with PfHsp70-1 and can stimulate its in vitro ATP hydrolysis activity
- (2015) James M. Njunge et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Overexpression, Purification and Characterisation of the Plasmodium falciparum Hsp70-z (PfHsp70-z) Protein
- (2015) Tawanda Zininga et al. PLoS One
- Plasmodium falciparum Hop (PfHop) Interacts with the Hsp70 Chaperone in a Nucleotide-Dependent Fashion and Exhibits Ligand Selectivity
- (2015) Tawanda Zininga et al. PLoS One
- Selective modulation of plasmodial Hsp70s by small molecules with antimalarial activity
- (2014) Ingrid L. Cockburn et al. BIOLOGICAL CHEMISTRY
- Protein export in malaria parasites: an update
- (2014) Brendan Elsworth et al. CELLULAR MICROBIOLOGY
- PTEX is an essential nexus for protein export in malaria parasites
- (2014) Brendan Elsworth et al. NATURE
- PTEX component HSP101 mediates export of diverse malaria effectors into host erythrocytes
- (2014) Josh R. Beck et al. NATURE
- Dual targeting of heat shock proteins 90 and 70 promotes cell death and enhances the anticancer effect of chemotherapeutic agents in bladder cancer
- (2014) LIANG MA et al. ONCOLOGY REPORTS
- Co-chaperones of Hsp90 in Plasmodium falciparum and their concerted roles in cellular regulation
- (2014) CHUN-SONG CHUA et al. PARASITOLOGY
- Plasmodial Hsp40 and Hsp70 chaperones: current and future perspectives
- (2014) E.-R. PESCE et al. PARASITOLOGY
- Population transcriptomics of human malaria parasites reveals the mechanism of artemisinin resistance
- (2014) S. Mok et al. SCIENCE
- The fungal Achilles’ heel: targeting Hsp90 to cripple fungal pathogens
- (2013) Leah E Cowen CURRENT OPINION IN MICROBIOLOGY
- ThePlasmodiumtranslocon of exported proteins (PTEX) component thioredoxin-2 is important for maintaining normal blood-stage growth
- (2013) Kathryn Matthews et al. MOLECULAR MICROBIOLOGY
- A Purine Analog Synergizes with Chloroquine (CQ) by Targeting Plasmodium falciparum Hsp90 (PfHsp90)
- (2013) Dea Shahinas et al. PLoS One
- Plasmodium falciparum-encoded exported hsp70/hsp40 chaperone/co-chaperone complexes within the host erythrocyte
- (2012) Simone Külzer et al. CELLULAR MICROBIOLOGY
- Hsp70s and J Proteins of Plasmodium Parasites Infecting Rodents and Primates: Structure, Function, Clinical Relevance, and Drug Targets
- (2012) James M. Njunge et al. CURRENT PHARMACEUTICAL DESIGN
- The epidemiology of postpartum malaria: a systematic review
- (2012) Machteld E Boel et al. MALARIA JOURNAL
- Molecular dynamics simulations of PfAQP from the malarial parasite Plasmodium falciparum
- (2012) Yubao Cui Molecular Medicine Reports
- An Exported Heat Shock Protein 40 Associates with Pathogenesis-Related Knobs in Plasmodium falciparum Infected Erythrocytes
- (2012) Pragyan Acharya et al. PLoS One
- A Major Genome Region Underlying Artemisinin Resistance in Malaria
- (2012) I. H. Cheeseman et al. SCIENCE
- Screening for small molecule modulators of Hsp70 chaperone activity using protein aggregation suppression assays: inhibition of the plasmodial chaperone PfHsp70-1
- (2011) Ingrid L. Cockburn et al. BIOLOGICAL CHEMISTRY
- Characterisation of the Plasmodium falciparum Hsp70–Hsp90 organising protein (PfHop)
- (2011) Grace W. Gitau et al. CELL STRESS & CHAPERONES
- Functional Analysis of the Exported Type IV HSP40 Protein PfGECO in Plasmodium falciparum Gametocytes
- (2011) Belinda J. Morahan et al. EUKARYOTIC CELL
- Drug-resistant malaria: Molecular mechanisms and implications for public health
- (2011) Ines Petersen et al. FEBS LETTERS
- Plasmodium sporozoite motility: an update
- (2011) Georgina et al. Frontiers in Bioscience-Landmark
- Co-expression of the Plasmodium falciparum molecular chaperone, PfHsp70, improves the heterologous production of the antimalarial drug target GTP cyclohydrolase I, PfGCHI
- (2011) Linda L. Stephens et al. PROTEIN EXPRESSION AND PURIFICATION
- The pathogenesis of Plasmodium falciparum malaria in humans: insights from splenic physiology
- (2010) P. A. Buffet et al. BLOOD
- Parasite-encoded Hsp40 proteins define novel mobile structures in the cytosol of the P. falciparum-infected erythrocyte
- (2010) Simone Külzer et al. CELLULAR MICROBIOLOGY
- Heat Shock Protein 90 as a Drug Target against Protozoan Infections
- (2010) Rani Pallavi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Malaria Parasite Actin Polymerization and Filament Structure
- (2010) Stephan Schmitz et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Chaperone expression profiles correlate with distinct physiological states of Plasmodium falciparum in malaria patients
- (2010) Rani Pallavi et al. MALARIA JOURNAL
- Moving in and renovating: exporting proteins from Plasmodium into host erythrocytes
- (2010) Daniel E. Goldberg et al. NATURE REVIEWS MICROBIOLOGY
- A Large Proportion of P. falciparum Isolates in the Amazon Region of Peru Lack pfhrp2 and pfhrp3: Implications for Malaria Rapid Diagnostic Tests
- (2010) Dionicia Gamboa et al. PLoS One
- Select pyrimidinones inhibit the propagation of the malarial parasite, Plasmodium falciparum
- (2009) Annette N. Chiang et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Plasmodial heat shock proteins: targets for chemotherapy
- (2009) Addmore Shonhai FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY
- Co-ordinated stage-dependent enhancement of Plasmodium falciparum antioxidant enzymes and heat shock protein expression in parasites growing in oxidatively stressed or G6PD-deficient red blood cells
- (2009) Oscar Akide-Ndunge et al. MALARIA JOURNAL
- A Small Molecule Inhibitor of Inducible Heat Shock Protein 70
- (2009) J. I-Ju Leu et al. MOLECULAR CELL
- Malaria parasite proteins that remodel the host erythrocyte
- (2009) Alexander G. Maier et al. NATURE REVIEWS MICROBIOLOGY
- Protein export in malaria parasites: do multiple export motifs add up to multiple export pathways?
- (2009) Tobias Spielmann et al. TRENDS IN PARASITOLOGY
- Exported Proteins Required for Virulence and Rigidity of Plasmodium falciparum-Infected Human Erythrocytes
- (2008) Alexander G. Maier et al. CELL
- Molecular Chaperones in Pathogen Virulence: Emerging New Targets for Therapy
- (2008) Len Neckers et al. Cell Host & Microbe
- Malaria: progress, perils, and prospects for eradication
- (2008) Brian M. Greenwood et al. JOURNAL OF CLINICAL INVESTIGATION
- PlasmoDB: a functional genomic database for malaria parasites
- (2008) C. Aurrecoechea et al. NUCLEIC ACIDS RESEARCH
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now