Uncovering the essential genes of the human malaria parasitePlasmodium falciparumby saturation mutagenesis

A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes

(2016) Saima M. Sidik et al.   CELL

Quantitative insertion-site sequencing (QIseq) for high throughput phenotyping of transposon mutants

(2016) Iraad F. Bronner et al.   GENOME RESEARCH

Structure- and function-based design of Plasmodium-selective proteasome inhibitors

(2016) Hao Li et al.   NATURE

Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond

(2016) Wesley C. Van Voorhis et al.   PLoS Pathogens

Translational regulation in blood stages of the malaria parasite Plasmodium spp. : systems-wide studies pave the way

(2016) Shruthi Sridhar Vembar et al.   Wiley Interdisciplinary Reviews-RNA

High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities

(2015) Traver Hart et al.   CELL

A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria

(2015) Alassane Mbengue et al.   NATURE

Advances in molecular genetic systems in malaria

(2015) Tania F. de Koning-Ward et al.   NATURE REVIEWS MICROBIOLOGY

Gene essentiality and synthetic lethality in haploid human cells

(2015) V. A. Blomen et al.   SCIENCE

Identification and characterization of essential genes in the human genome

(2015) T. Wang et al.   SCIENCE

Chemogenomic profiling of Plasmodium falciparum as a tool to aid antimalarial drug discovery

(2015) Anupam Pradhan et al.   Scientific Reports

Targeting the Cell Stress Response of Plasmodium falciparum to Overcome Artemisinin Resistance

(2015) Con Dogovski et al.   PLOS BIOLOGY

Exonuclease-mediated degradation of nascent RNA silences genes linked to severe malaria

(2014) Qingfeng Zhang et al.   NATURE

Genome editing in the human malaria parasite Plasmodium falciparum using the CRISPR-Cas9 system

(2014) Mehdi Ghorbal et al.   NATURE BIOTECHNOLOGY

Efficient CRISPR-Cas9–mediated genome editing in Plasmodium falciparum

(2014) Jeffrey C Wagner et al.   NATURE METHODS

Spread of Artemisinin Resistance in Plasmodium falciparum Malaria

(2014) Elizabeth A. Ashley et al.   NEW ENGLAND JOURNAL OF MEDICINE

Atypical Mitogen-Activated Protein Kinase Phosphatase Implicated in Regulating Transition from Pre-S-Phase Asexual Intraerythrocytic Development of Plasmodium falciparum

(2013) Bharath Balu et al.   EUKARYOTIC CELL

Transposon mutagenesis identifies genes essential for Plasmodium falciparum gametocytogenesis

(2013) H. Ikadai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Plasmodium falciparum phosphoethanolamine methyltransferase is essential for malaria transmission

(2013) A. M. Bobenchik et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

EuPathDB: The Eukaryotic Pathogen database

(2012) C. Aurrecoechea et al.   NUCLEIC ACIDS RESEARCH

Directional gene expression and antisense transcripts in sexual and asexual stages of Plasmodium falciparum

(2011) María J López-Barragán et al.   BMC GENOMICS

CCR4-Associated Factor 1 Coordinates the Expression of Plasmodium falciparum Egress and Invasion Proteins

(2011) Bharath Balu et al.   EUKARYOTIC CELL

Jumbled Genomes: Missing Apicomplexan Synteny

(2011) J. D. DeBarry et al.   MOLECULAR BIOLOGY AND EVOLUTION

Nucleosome landscape and control of transcription in the human malaria parasite

(2010) N. Ponts et al.   GENOME RESEARCH

New insights into the blood-stage transcriptome ofPlasmodium falciparumusing RNA-Seq

(2010) Thomas D. Otto et al.   MOLECULAR MICROBIOLOGY

Identification and Genome-Wide Prediction of DNA Binding Specificities for the ApiAP2 Family of Regulators from the Malaria Parasite

(2010) Tracey L. Campbell et al.   PLoS Pathogens

piggyBac is an effective tool for functional analysis of the Plasmodium falciparum genome

(2009) Bharath Balu et al.   BMC MICROBIOLOGY