Artemisinin activity-based probes identify multiple molecular targets within the asexual stage of the malaria parasitesPlasmodium falciparum3D7

Efficacy and safety of RTS,S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial

(2015)   LANCET

Wolbachia lipoproteins: abundance, localisation and serology of Wolbachia peptidoglycan associated lipoprotein and the Type IV Secretion System component, VirB6 from Brugia malayi and Aedes albopictus

(2014) Denis Voronin et al.   Parasites & Vectors

A Chemical Proteomics Approach for the Search of Pharmacological Targets of the Antimalarial Clinical Candidate Albitiazolium in Plasmodium falciparum Using Photocrosslinking and Click Chemistry

(2014) Diana Marcela Penarete-Vargas et al.   PLoS One

Population transcriptomics of human malaria parasites reveals the mechanism of artemisinin resistance

(2014) S. Mok et al.   SCIENCE

The proliferating cell hypothesis: a metabolic framework for Plasmodium growth and development

(2014) J. Enrique Salcedo-Sora et al.   TRENDS IN PARASITOLOGY

Efficacy and Safety of the RTS,S/AS01 Malaria Vaccine during 18 Months after Vaccination: A Phase 3 Randomized, Controlled Trial in Children and Young Infants at 11 African Sites

(2014)   PLOS MEDICINE

Rapid kill of malaria parasites by artemisinin and semi-synthetic endoperoxides involves ROS-dependent depolarization of the membrane potential

(2013) Thomas Antoine et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

A molecular marker of artemisinin-resistant Plasmodium falciparum malaria

(2013) Frédéric Ariey et al.   NATURE

STITCH 4: integration of protein–chemical interactions with user data

(2013) Michael Kuhn et al.   NUCLEIC ACIDS RESEARCH

Pyrethroid activity-based probes for profiling cytochrome P450 activities associated with insecticide interactions

(2013) H. M. Ismail et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A travel guide to Cytoscape plugins

(2012) Rintaro Saito et al.   NATURE METHODS

Malarial dihydrofolate reductase as a paradigm for drug development against a resistance-compromised target

(2012) Y. Yuthavong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein S-Glutathionylation in Malaria Parasites

(2011) Sebastian Kehr et al.   ANTIOXIDANTS & REDOX SIGNALING

Purine and Pyrimidine Pathways as Targets in Plasmodium falciparum

(2011) Maria Belen Cassera et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Molecular chaperones in protein folding and proteostasis

(2011) F. Ulrich Hartl et al.   NATURE

Artemisinin activity against Plasmodium falciparum requires hemoglobin uptake and digestion

(2011) N. Klonis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Facile Oxidation of Leucomethylene Blue and Dihydroflavins by Artemisinins: Relationship with Flavoenzyme Function and Antimalarial Mechanism of Action

(2010) Richard K. Haynes et al.   ChemMedChem

The Role of Heme and the Mitochondrion in the Chemical and Molecular Mechanisms of Mammalian Cell Death Induced by the Artemisinin Antimalarials

(2010) Amy E. Mercer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Redox Regulation of Plasmodium falciparum Ornithine δ-Aminotransferase

(2010) Esther Jortzik et al.   JOURNAL OF MOLECULAR BIOLOGY

Central carbon metabolism of Plasmodium parasites

(2010) Kellen L. Olszewski et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

The Molecular Mechanism of Action of Artemisinin—The Debate Continues

(2010) Paul M. O’Neill et al.   MOLECULES

Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality

(2009) Ellen M. Sletten et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks

(2009) Gabriela Bindea et al.   BIOINFORMATICS

Alkylating ability of artemisinin after Cu(I)-induced activation

(2009) Fatima Bousejra-El Garah et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Heme activates artemisinin more efficiently than hemin, inorganic iron, or hemoglobin

(2008) Shiming Zhang et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Plasmodium Food Vacuole Plasmepsins Are Activated by Falcipains

(2008) Mark E. Drew et al.   JOURNAL OF BIOLOGICAL CHEMISTRY