Comparative Genomics of Marine Sponge-Derived Streptomyces spp. Isolates SM17 and SM18 With Their Closest Terrestrial Relatives Provides Novel Insights Into Environmental Niche Adaptations and Secondary Metabolite Biosynthesis Potential

antiSMASH 5.0: updates to the secondary metabolite genome mining pipeline

(2019) Kai Blin et al.   NUCLEIC ACIDS RESEARCH

Control of Specialized Metabolism by Signaling and Transcriptional Regulation: Opportunities for New Platforms for Drug Discovery?

(2018) M. Daniel-Ivad et al.   Annual Review of Microbiology

Cracking the regulatory code of biosynthetic gene clusters as a strategy for natural product discovery

(2018) Sébastien Rigali et al.   BIOCHEMICAL PHARMACOLOGY

Diverse and Abundant Secondary Metabolism Biosynthetic Gene Clusters in the Genomes of Marine Sponge Derived Streptomyces spp. Isolates

(2018) Stephen Jackson et al.   Marine Drugs

Identification and Characterization of Mycemycin Biosynthetic Gene Clusters in Streptomyces olivaceus FXJ8.012 and Streptomyces sp. FXJ1.235

(2018) Fangying Song et al.   Marine Drugs

Fluostatins M–Q Featuring a 6-5-6-6 Ring Skeleton and High Oxidized A-Rings from Marine Streptomyces sp. PKU-MA00045

(2018) Jing Jin et al.   Marine Drugs

Marine sponge microbial association: Towards disclosing unique symbiotic interactions

(2018) G. Seghal Kiran et al.   MARINE ENVIRONMENTAL RESEARCH

Rational engineering of Streptomyces albus J1074 for the overexpression of secondary metabolite gene clusters

(2018) Dimitris Kallifidas et al.   Microbial Cell Factories

MEGA X: Molecular Evolutionary Genetics Analysis across Computing Platforms

(2018) Sudhir Kumar et al.   MOLECULAR BIOLOGY AND EVOLUTION

Genome mining of Streptomyces scabrisporus NF3 reveals symbiotic features including genes related to plant interactions

(2018) Corina Diana Ceapă et al.   PLoS One

Evolutionary stability of antibiotic protection in a defensive symbiosis

(2018) Tobias Engl et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome plasticity is governed by double strand break DNA repair in Streptomyces

(2018) Grégory Hoff et al.   Scientific Reports

Editorial: The Search for Biological Active Agent(s) From Actinobacteria

(2018) Learn-Han Lee et al.   Frontiers in Microbiology

Specificity and Application of the Lantibiotic Protease NisP

(2018) Manuel Montalbán-López et al.   Frontiers in Microbiology

Comparative Genomics Provides Insights Into the Marine Adaptation in Sponge-Derived Kocuriaflava S43

(2018) Wei Sun et al.   Frontiers in Microbiology

Comparative Genomics of Completely Sequenced Lactobacillus helveticus Genomes Provides Insights into Strain-Specific Genes and Resolves Metagenomics Data Down to the Strain Level

(2018) Michael Schmid et al.   Frontiers in Microbiology

Genome Mining of the Marine Actinomycete Streptomyces sp. DUT11 and Discovery of Tunicamycins as Anti-complement Agents

(2018) Xiao-Na Xu et al.   Frontiers in Microbiology

Antibiotic Resistance Mediated by the MacB ABC Transporter Family: A Structural and Functional Perspective

(2018) Nicholas P. Greene et al.   Frontiers in Microbiology

Butenolides from Streptomyces albus J1074 Act as External Signals To Stimulate Avermectin Production in Streptomyces avermitilis

(2018) Thao Bich Nguyen et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

OpuF, a New Bacillus Compatible Solute ABC Transporter with a Substrate-Binding Protein Fused to the Transmembrane Domain

(2018) Laura Teichmann et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

The Pfam protein families database in 2019

(2018) Sara El-Gebali et al.   NUCLEIC ACIDS RESEARCH

InterPro in 2019: improving coverage, classification and access to protein sequence annotations

(2018) Alex L Mitchell et al.   NUCLEIC ACIDS RESEARCH

Genome Mining for Mycemycin: Discovery and Elucidation of Related Methylation and Chlorination Biosynthetic Chemistries

(2018) Chunyan Zhang et al.   ORGANIC LETTERS

Cloning and Expression of the Chitinase Encoded by ChiKJ406136 from Streptomyces Sampsonii (Millard & Burr) Waksman KJ40 and Its Antifungal Effect

(2018) Shujiang Li et al.   Forests

Emerging biopharmaceuticals from marine actinobacteria

(2017) Syed Shams ul Hassan et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Canu: scalable and accurate long-read assembly via adaptivek-mer weighting and repeat separation

(2017) Sergey Koren et al.   GENOME RESEARCH

Metagenomic binning of a marine sponge microbiome reveals unity in defense but metabolic specialization

(2017) Beate M Slaby et al.   ISME Journal

Characterization of bafilomycin biosynthesis in Kitasatospora setae KM-6054 and comparative analysis of gene clusters in Actinomycetales microorganisms

(2017) Ayako Nara et al.   JOURNAL OF ANTIBIOTICS

Beta-lactamase database (BLDB) – structure and function

(2017) Thierry Naas et al.   JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY

Tryptorubin A: A Polycyclic Peptide from a Fungus-Derived Streptomycete

(2017) Thomas P. Wyche et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Isolation of Petrocidin A, a New Cytotoxic Cyclic Dipeptide from the Marine Sponge-Derived Bacterium Streptomyces sp. SBT348

(2017) Cheng Cheng et al.   Marine Drugs

Novel Bioactive Paulomycin Derivatives Produced by Streptomyces albus J1074

(2017) Jorge Fernández-De la Hoz et al.   MOLECULES

Symbiosis-inspired approaches to antibiotic discovery

(2017) Navid Adnani et al.   NATURAL PRODUCT REPORTS

GenBank

(2017) Dennis A Benson et al.   NUCLEIC ACIDS RESEARCH

antiSMASH 4.0—improvements in chemistry prediction and gene cluster boundary identification

(2017) Kai Blin et al.   NUCLEIC ACIDS RESEARCH

Volatiles from the fungal microbiome of the marine sponge Callyspongia cf. flammea

(2017) Lena Barra et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Secondary Metabolites Produced during the Germination of Streptomyces coelicolor

(2017) Matouš Čihák et al.   Frontiers in Microbiology

Focused Review: Cytotoxic and Antioxidant Potentials of Mangrove-Derived Streptomyces

(2017) Hooi-Leng Ser et al.   Frontiers in Microbiology

Deep Sea Actinomycetes and Their Secondary Metabolites

(2017) Manita Kamjam et al.   Frontiers in Microbiology

Caboxamycin biosynthesis pathway and identification of novel benzoxazoles produced by cross-talk in Streptomyces sp. NTK 937

(2017) Armando A. Losada et al.   Microbial Biotechnology

New natural products identified by combined genomics-metabolomics profiling of marine Streptomyces sp. MP131-18

(2017) Constanze Paulus et al.   Scientific Reports

Multiple Streptomyces species with distinct secondary metabolomes have identical 16S rRNA gene sequences

(2017) Sanjay Antony-Babu et al.   Scientific Reports

The role of sponge-bacteria interactions: the sponge Aplysilla rosea challenged by its associated bacterium Streptomyces ACT-52A in a controlled aquarium system

(2016) Mohammad F. Mehbub et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Biosynthetic Gene Cluster for Surugamide A Encompasses an Unrelated Decapeptide, Surugamide F

(2016) Akihiro Ninomiya et al.   CHEMBIOCHEM

Do we need new antibiotics?

(2016) J.-M. Rolain et al.   CLINICAL MICROBIOLOGY AND INFECTION

Cell wall distracting anti-Methicillin-resistant Staphylococcus aureus compound PVI331 from a marine sponge associated Streptomyces

(2016) Appadurai Muthamil Iniyan et al.   Journal of Applied Biomedicine

Bioprospecting Sponge-Associated Microbes for Antimicrobial Compounds

(2016) Anak Indraningrat et al.   Marine Drugs

Evolution and function of eukaryotic-like proteins from sponge symbionts

(2016) David Reynolds et al.   MOLECULAR ECOLOGY

The evolution of genome mining in microbes – a review

(2016) Nadine Ziemert et al.   NATURAL PRODUCT REPORTS

NCBI prokaryotic genome annotation pipeline

(2016) Tatiana Tatusova et al.   NUCLEIC ACIDS RESEARCH

An Enrichment of CRISPR and Other Defense-Related Features in Marine Sponge-Associated Microbial Metagenomes

(2016) Hannes Horn et al.   Frontiers in Microbiology

Leisingera sp. JC1, a Bacterial Isolate from Hawaiian Bobtail Squid Eggs, Produces Indigoidine and Differentially Inhibits Vibrios

(2016) Samantha M. Gromek et al.   Frontiers in Microbiology

Characterization of a New S8 serine Protease from Marine Sedimentary Photobacterium sp. A5–7 and the Function of Its Protease-Associated Domain

(2016) Hui-Juan Li et al.   Frontiers in Microbiology

Comparative Genomics Analysis of Streptomyces Species Reveals Their Adaptation to the Marine Environment and Their Diversity at the Genomic Level

(2016) Xinpeng Tian et al.   Frontiers in Microbiology

The Crystal Structure of the YknZ Extracellular Domain of ABC Transporter YknWXYZ from Bacillus amyloliquefaciens

(2016) Yongbin Xu et al.   PLoS One

Characterization of the mechanism of prolonged adaptation to osmotic stress of Jeotgalibacillus malaysiensis via genome and transcriptome sequencing analyses

(2016) Amira Suriaty Yaakop et al.   Scientific Reports

Roary: rapid large-scale prokaryote pan genome analysis

(2015) Andrew J. Page et al.   BIOINFORMATICS

The Streptomyces leeuwenhoekii genome: de novo sequencing and assembly in single contigs of the chromosome, circular plasmid pSLE1 and linear plasmid pSLE2

(2015) Juan Pablo Gomez-Escribano et al.   BMC GENOMICS

Inhibitory activities of the marine streptomycete-derived compound SF2446A2 against Chlamydia trachomatis and Schistosoma mansoni

(2015) Anastasija Reimer et al.   JOURNAL OF ANTIBIOTICS

Stability of the Osmoregulated Promoter-DerivedproPmRNA Is Posttranscriptionally Regulated by RNase III in Escherichia coli

(2015) Boram Lim et al.   JOURNAL OF BACTERIOLOGY

Bacterial responses to osmotic challenges

(2015) Janet M. Wood   JOURNAL OF GENERAL PHYSIOLOGY

Mycemycins A–E, New Dibenzoxazepinones Isolated from Two Different Streptomycetes

(2015) Ning Liu et al.   Marine Drugs

Isolation and characterization of multifunctional Streptomyces species with antimicrobial, nematicidal and phytohormone activities from marine environments in Egypt

(2015) Ferial M. Rashad et al.   MICROBIOLOGICAL RESEARCH

Minimum Information about a Biosynthetic Gene cluster

(2015) Marnix H Medema et al.   Nature Chemical Biology

Discovery of microbial natural products by activation of silent biosynthetic gene clusters

(2015) Peter J. Rutledge et al.   NATURE REVIEWS MICROBIOLOGY

Diversity of cultivable protease-producing bacteria in sediments of Jiaozhou Bay, China

(2015) Xi-Ying Zhang et al.   Frontiers in Microbiology

The Split-Apply-Combine Strategy for Data Analysis

(2015) Hadley Wickham   Journal of Statistical Software

Bacterial Sigma Factors: A Historical, Structural, and Genomic Perspective

(2014) Andrey Feklístov et al.   Annual Review of Microbiology

Diversity and biotechnological potential of microorganisms associated with marine sponges

(2014) John A. Fuerst   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Prokka: rapid prokaryotic genome annotation

(2014) T. Seemann   BIOINFORMATICS

Marine actinobacteria: An important source of bioactive natural products

(2014) Panchanathan Manivasagan et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Antimicrobial resistance: impact on clinical and economic outcomes and the need for new antimicrobials

(2014) Abrar K Thabit et al.   EXPERT OPINION ON PHARMACOTHERAPY

Defensive symbiosis: a microbial perspective

(2014) Keith Clay   FUNCTIONAL ECOLOGY

Antibiotic activity and microbial community of the temperate sponge,Haliclonasp.

(2014) A. Hoppers et al.   JOURNAL OF APPLIED MICROBIOLOGY

Structural diversity of ABC transporters

(2014) Josy ter Beek et al.   JOURNAL OF GENERAL PHYSIOLOGY

Diversity, abundance and natural products of marine sponge-associated actinomycetes

(2014) Usama Ramadan Abdelmohsen et al.   NATURAL PRODUCT REPORTS

CDD: NCBI's conserved domain database

(2014) Aron Marchler-Bauer et al.   NUCLEIC ACIDS RESEARCH

UniProt: a hub for protein information

(2014)   NUCLEIC ACIDS RESEARCH

Genomics of Sponge-Associated Streptomyces spp. Closely Related to Streptomyces albus J1074: Insights into Marine Adaptation and Secondary Metabolite Biosynthesis Potential

(2014) Elena Ian et al.   PLoS One

Host Control of Symbiont Natural Product Chemistry in Cryptic Populations of the Tunicate Lissoclinum patella

(2014) Jason C. Kwan et al.   PLoS One

Terpene synthases are widely distributed in bacteria

(2014) Yuuki Yamada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of Copper Treatment on the Composition and Function of the Bacterial Community in the Sponge Haliclona cymaeformis

(2014) Ren-Mao Tian et al.   mBio

Metabolic profiles of prokaryotic and eukaryotic communities in deep-sea sponge Neamphius huxleyi indicated by metagenomics

(2014) Zhi-Yong Li et al.   Scientific Reports

QUAST: quality assessment tool for genome assemblies

(2013) Alexey Gurevich et al.   BIOINFORMATICS

Systems biology and biotechnology of Streptomyces species for the production of secondary metabolites

(2013) Kyu-Sang Hwang et al.   BIOTECHNOLOGY ADVANCES

Characterization of the Bafilomycin Biosynthetic Gene Cluster fromStreptomyces lohii

(2013) Wei Zhang et al.   CHEMBIOCHEM

The genusPseudovibriocontains metabolically versatile bacteria adapted for symbiosis

(2013) Vladimir Bondarev et al.   ENVIRONMENTAL MICROBIOLOGY

Commercial proteases: Present and future

(2013) Qing Li et al.   FEBS LETTERS

Marine microbial symbiosis heats up: the phylogenetic and functional response of a sponge holobiont to thermal stress

(2013) Lu Fan et al.   ISME Journal

Fusion of Dioxygenase and Lignin-binding Domains in a Novel Secreted Enzyme from CellulolyticStreptomycessp. SirexAA-E

(2013) Christopher M. Bianchetti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Two-component systems in Streptomyces: key regulators of antibiotic complex pathways

(2013) Héctor Rodríguez et al.   Microbial Cell Factories

The TetR Family of Regulators

(2013) L. Cuthbertson et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

MAFFT Multiple Sequence Alignment Software Version 7: Improvements in Performance and Usability

(2013) K. Katoh et al.   MOLECULAR BIOLOGY AND EVOLUTION

Advantages of Single-Molecule Real-Time Sequencing in High-GC Content Genomes

(2013) Seung Chul Shin et al.   PLoS One

Marine Sediment-Derived Streptomyces Bacteria from British Columbia, Canada Are a Promising Microbiota Resource for the Discovery of Antimicrobial Natural Products

(2013) Doralyn S. Dalisay et al.   PLoS One

Surviving in a Marine Desert: The Sponge Loop Retains Resources Within Coral Reefs

(2013) Jasper M. de Goeij et al.   SCIENCE

Classification of Streptomyces phylogroup pratensis (Doroghazi and Buckley, 2010) based on genetic and phenotypic evidence, and proposal of Streptomyces pratensis sp. nov.

(2013) Xiaoying Rong et al.   SYSTEMATIC AND APPLIED MICROBIOLOGY

Activation and characterization of a cryptic polycyclic tetramate macrolactam biosynthetic gene cluster

(2013) Yunzi Luo et al.   Nature Communications

Osmoadaptation and plant growth promotion by salt tolerant bacteria under salt stress

(2012) Aisha Waheed Qurashi   African Journal of Microbiology Research

Assessing the Contributions of the LiaS Histidine Kinase to the Innate Resistance of Listeria monocytogenes to Nisin, Cephalosporins, and Disinfectants

(2012) Barry Collins et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Genome plasticity and systems evolution in Streptomyces

(2012) Zhan Zhou et al.   BMC BIOINFORMATICS

Genomic and transcriptomic insights into the thermo-regulated biosynthesis of validamycin in Streptomyces hygroscopicus 5008

(2012) Hang Wu et al.   BMC GENOMICS

Comparative genomics reveals evidence of marine adaptation in Salinispora species

(2012) Kevin Penn et al.   BMC GENOMICS

Characterization of replication and conjugation of plasmid pWTY27 from a widely distributed Streptomyces species

(2012) Tao Wang et al.   BMC MICROBIOLOGY

Copper-responsive gene regulation in bacteria

(2012) C. Rademacher et al.   MICROBIOLOGY-SGM

Crystal Structures of Two Transcriptional Regulators from Bacillus cereus Define the Conserved Structural Features of a PadR Subfamily

(2012) Guntur Fibriansah et al.   PLoS One

Functional equivalence and evolutionary convergence in complex communities of microbial sponge symbionts

(2012) L. Fan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MrBayes 3.2: Efficient Bayesian Phylogenetic Inference and Model Choice Across a Large Model Space

(2012) Fredrik Ronquist et al.   SYSTEMATIC BIOLOGY

Evolution of genome base composition and genome size in bacteria

(2012) Hiromi Nishida   Frontiers in Microbiology

Characterization of the multiple CRISPR loci on Streptomyces linear plasmid pSHK1

(2011) Peng Guo et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

BamTools: a C++ API and toolkit for analyzing and managing BAM files

(2011) D. W. Barnett et al.   BIOINFORMATICS

Antibiotics as Signal Molecules

(2011) Diego Romero et al.   CHEMICAL REVIEWS

Diversity and antimicrobial activities of microbes from two Irish marine sponges, Suberites carnosus and Leucosolenia sp.

(2011) B. Flemer et al.   JOURNAL OF APPLIED MICROBIOLOGY

A Single Streptomyces Symbiont Makes Multiple Antifungals to Support the Fungus Farming Ant Acromyrmex octospinosus

(2011) Ryan F. Seipke et al.   PLoS One

Disruption of the siderophore-binding desE receptor gene in Streptomyces coelicolor A3(2) results in impaired growth in spite of multiple iron-siderophore transport systems

(2011) Víctor H. Tierrafría et al.   Microbial Biotechnology

A guide to successful bioprospecting: informed by actinobacterial systematics

(2010) Michael Goodfellow et al.   ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY

Bacterial stimulus perception and signal transduction: Response to osmotic stress

(2010) Reinhard Krämer   CHEMICAL RECORD

Toxin–antitoxin systems: why so many, what for?

(2010) Laurence Van Melderen   CURRENT OPINION IN MICROBIOLOGY

Functional genomic signatures of sponge bacteria reveal unique and shared features of symbiosis

(2010) Torsten Thomas et al.   ISME Journal

A new angucycline and a new butenolide isolated from lichen-derived Streptomyces spp.

(2010) Keiichiro Motohashi et al.   JOURNAL OF ANTIBIOTICS

Daptomycin, a Bacterial Lipopeptide Synthesized by a Nonribosomal Machinery

(2010) Lars Robbel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mayamycin, a Cytotoxic Polyketide from aStreptomycesStrain Isolated from the Marine SpongeHalichondria panicea

(2010) Imke Schneemann et al.   JOURNAL OF NATURAL PRODUCTS

Production of Lantipeptides inEscherichia coli

(2010) Yanxiang Shi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chemistry and biology of siderophores

(2010) Robert C. Hider et al.   NATURAL PRODUCT REPORTS

CDD: a Conserved Domain Database for the functional annotation of proteins

(2010) A. Marchler-Bauer et al.   NUCLEIC ACIDS RESEARCH

Caboxamycin, a new antibiotic of the benzoxazole family produced by the deep-sea strain Streptomyces sp. NTK 937

(2009) Claudia Hohmann et al.   JOURNAL OF ANTIBIOTICS

DNAPlotter: circular and linear interactive genome visualization

(2008) T. Carver et al.   BIOINFORMATICS

StreptomycesTelomeres Contain a Promoter

(2008) Yuh-ru Lin et al.   JOURNAL OF BACTERIOLOGY

Intracellular Organic Osmolytes: Function and Regulation

(2008) Maurice B. Burg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phylogenetic Diversity and Antimicrobial Activities of Fungi Associated with Haliclona simulans Isolated from Irish Coastal Waters

(2008) Paul W. Baker et al.   MARINE BIOTECHNOLOGY

Isolation and Analysis of Bacteria with Antimicrobial Activities from the Marine Sponge Haliclona simulans Collected from Irish Waters

(2008) Jonathan Kennedy et al.   MARINE BIOTECHNOLOGY

Structure and function of the LysR-type transcriptional regulator (LTTR) family proteins

(2008) S. E. Maddocks et al.   MICROBIOLOGY-SGM

NCBI BLAST: a better web interface

(2008) M. Johnson et al.   NUCLEIC ACIDS RESEARCH