标题
Epigenetics in cancer therapy and nanomedicine
作者
关键词
-
出版物
Clinical Epigenetics
Volume 11, Issue 1, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2019-05-16
DOI
10.1186/s13148-019-0675-4
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Targeting Epigenetics in Cancer
- (2018) Richard L. Bennett et al. Annual Review of Pharmacology and Toxicology
- The DOT1L inhibitor pinometostat reduces H3K79 methylation and has modest clinical activity in adult acute leukemia
- (2018) Eytan M. Stein et al. BLOOD
- Non-coding RNAs, epigenetics, and cancer: tying it all together
- (2018) Humberto J. Ferreira et al. CANCER AND METASTASIS REVIEWS
- Stimuli Responsive Nanoparticles for Controlled Anti-cancer Drug Release
- (2018) Qi Tang et al. CURRENT MEDICINAL CHEMISTRY
- Current progress and challenges of nanoparticle-based therapeutics in pain management
- (2018) Vanesa Andreu et al. JOURNAL OF CONTROLLED RELEASE
- Nucleosidic DNA demethylating epigenetic drugs – A comprehensive review from discovery to clinic
- (2018) Khushboo Agrawal et al. PHARMACOLOGY & THERAPEUTICS
- Nanogel-mediated delivery of a cocktail of epigenetic drugs plus doxorubicin overcomes drug resistance in breast cancer cells
- (2018) Sivakumar Vijayaraghavalu et al. Drug Delivery and Translational Research
- Combination Therapy With Histone Deacetylase Inhibitors (HDACi) for the Treatment of Cancer: Achieving the Full Therapeutic Potential of HDACi
- (2018) Amila Suraweera et al. Frontiers in Oncology
- Clinical epigenetics: seizing opportunities for translation
- (2018) María Berdasco et al. NATURE REVIEWS GENETICS
- Immunotoxicity, genotoxicity and epigenetic toxicity of nanomaterials: New strategies for toxicity testing?
- (2017) Maria Dusinska et al. FOOD AND CHEMICAL TOXICOLOGY
- Bone-targeting nanoparticle to co-deliver decitabine and arsenic trioxide for effective therapy of myelodysplastic syndrome with low systemic toxicity
- (2017) Xiaoyan Wu et al. JOURNAL OF CONTROLLED RELEASE
- Pendant HDAC inhibitor SAHA derivatised polymer as a novel prodrug micellar carrier for anticancer drugs
- (2017) Jieni Xu et al. JOURNAL OF DRUG TARGETING
- Parameters Affecting the Enhanced Permeability and Retention Effect: The Need for Patient Selection
- (2017) Az Alddien Natfji et al. JOURNAL OF PHARMACEUTICAL SCIENCES
- Epigenetics and immunotherapy: The current state of play
- (2017) Jennifer Dunn et al. MOLECULAR IMMUNOLOGY
- Triplet therapy with afatinib, cetuximab, and bevacizumab induces deep remission in lung cancer cells harboring EGFR T790M in vivo
- (2017) Kenichiro Kudo et al. Molecular Oncology
- DNA methylation changes in human lung epithelia cells exposed to multi-walled carbon nanotubes
- (2017) Marta I. Sierra et al. Nanotoxicology
- DNA methylation markers for diagnosis and prognosis of common cancers
- (2017) Xiaoke Hao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The cancer epigenome: Concepts, challenges, and therapeutic opportunities
- (2017) Mark A. Dawson SCIENCE
- Biological Identity of Nanoparticles In Vivo : Clinical Implications of the Protein Corona
- (2017) Giulio Caracciolo et al. TRENDS IN BIOTECHNOLOGY
- Advances in the delivery of RNA therapeutics: from concept to clinical reality
- (2017) James C. Kaczmarek et al. Genome Medicine
- Targeting Strategies for the Combination Treatment of Cancer Using Drug Delivery Systems
- (2017) Janel Kydd et al. Pharmaceutics
- Liposomal Formulations in Clinical Use: An Updated Review
- (2017) Upendra Bulbake et al. Pharmaceutics
- Epigenetic targeting drugs potentiate chemotherapeutic effects in solid tumor therapy
- (2017) Jingjing Li et al. Scientific Reports
- lncRNAs and microRNAs with a role in cancer development
- (2016) Julia Liz et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- The effect of exposure to nanoparticles and nanomaterials on the mammalian epigenome
- (2016) Marta I. Sierra et al. International Journal of Nanomedicine
- Epigenetic profiling to classify cancer of unknown primary: a multicentre, retrospective analysis
- (2016) Sebastian Moran et al. LANCET ONCOLOGY
- Safety and Efficacy in Advanced Solid Tumors of a Targeted Nanocomplex Carrying the p53 Gene Used in Combination with Docetaxel: A Phase 1b Study
- (2016) Kathleen F Pirollo et al. MOLECULAR THERAPY
- Targeting cancer with hyaluronic acid-based nanocarriers: recent advances and translational perspectives
- (2016) Ana Cadete et al. Nanomedicine
- Quantitative comparison of DNA methylation assays for biomarker development and clinical applications
- (2016) Christoph Bock et al. NATURE BIOTECHNOLOGY
- Targeting EZH2 in cancer
- (2016) Kimberly H Kim et al. NATURE MEDICINE
- Epigenetic modulators, modifiers and mediators in cancer aetiology and progression
- (2016) Andrew P. Feinberg et al. NATURE REVIEWS GENETICS
- Targeting the cancer epigenome for therapy
- (2016) Peter A. Jones et al. NATURE REVIEWS GENETICS
- The molecular hallmarks of epigenetic control
- (2016) C. David Allis et al. NATURE REVIEWS GENETICS
- Epigenetic Determinants of Cancer
- (2016) Stephen B. Baylin et al. Cold Spring Harbor Perspectives in Biology
- Type II enteropathy-associated T-cell lymphoma features a unique genomic profile with highly recurrent SETD2 alterations
- (2016) Annalisa Roberti et al. Nature Communications
- Changes of bivalent chromatin coincide with increased expression of developmental genes in cancer
- (2016) Stephan H. Bernhart et al. Scientific Reports
- Nanoparticle formulations of histone deacetylase inhibitors for effective chemoradiotherapy in solid tumors
- (2015) Edina C. Wang et al. BIOMATERIALS
- DNA demethylation and invasive cancer: implications for therapeutics
- (2015) David Cheishvili et al. BRITISH JOURNAL OF PHARMACOLOGY
- DNA-Demethylating Agents Target Colorectal Cancer Cells by Inducing Viral Mimicry by Endogenous Transcripts
- (2015) David Roulois et al. CELL
- Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses
- (2015) Katherine B. Chiappinelli et al. CELL
- Molecular Pathways: At the Crossroads of Cancer Epigenetics and Immunotherapy
- (2015) M. Maio et al. CLINICAL CANCER RESEARCH
- Histone deacetylase inhibitor-polymer conjugate nanoparticles for acid-responsive drug delivery
- (2015) Iza Denis et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Advancements in the delivery of epigenetic drugs
- (2015) Samantha A Cramer et al. Expert Opinion on Drug Delivery
- Nanoparticles in food. Epigenetic changes induced by nanomaterials and possible impact on health
- (2015) Bozena Smolkova et al. FOOD AND CHEMICAL TOXICOLOGY
- Two distinct modes for propagation of histone PTMs across the cell cycle
- (2015) Constance Alabert et al. GENES & DEVELOPMENT
- Advanced targeted nanomedicine
- (2015) Mohan C.M. Arachchige et al. JOURNAL OF BIOTECHNOLOGY
- Vorinostat, a histone deacetylase (HDAC) inhibitor, promotes cell cycle arrest and re-sensitizes rituximab- and chemo-resistant lymphoma cells to chemotherapy agents
- (2015) Kai Xue et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- H3K4/H3K9me3 Bivalent Chromatin Domains Targeted by Lineage-Specific DNA Methylation Pauses Adipocyte Differentiation
- (2015) Yoshihiro Matsumura et al. MOLECULAR CELL
- TET2 mutations predict response to hypomethylating agents in myelodysplastic syndrome patients
- (2014) R. Bejar et al. BLOOD
- Hyaluronic acid-coated solid lipid nanoparticles for targeted delivery of vorinostat to CD44 overexpressing cancer cells
- (2014) Tuan Hiep Tran et al. CARBOHYDRATE POLYMERS
- Delivery of epidrugs
- (2014) Fatima el Bahhaj et al. DRUG DISCOVERY TODAY
- Lipid based nanocarrier system for the potential oral delivery of decitabine: Formulation design, characterization, ex vivo, and in vivo assessment
- (2014) Yub Raj Neupane et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Epigenomic alterations define lethal CIMP-positive ependymomas of infancy
- (2014) S. C. Mack et al. NATURE
- Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia
- (2014) Liran I. Shlush et al. NATURE
- Development of Vorinostat-Loaded Solid Lipid Nanoparticles to Enhance Pharmacokinetics and Efficacy against Multidrug-Resistant Cancer Cells
- (2014) Tuan Hiep Tran et al. PHARMACEUTICAL RESEARCH
- Novel Epigenetic Target Therapy for Prostate Cancer: A Preclinical Study
- (2014) Ilaria Naldi et al. PLoS One
- Correlating animal and human phase Ia/Ib clinical data with CALAA-01, a targeted, polymer-based nanoparticle containing siRNA
- (2014) J. E. Zuckerman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- RNAi Therapies: Drugging the Undruggable
- (2014) S. Y. Wu et al. Science Translational Medicine
- Tumor Vasculature Targeting: A Generally Applicable Approach for Functionalized Nanomaterials
- (2014) Feng Chen et al. Small
- Mutations in epigenetic regulators including SETD2 are gained during relapse in paediatric acute lymphoblastic leukaemia
- (2014) Brenton G. Mar et al. Nature Communications
- Pancreatic cancer gene therapy using an siRNA-functionalized single walled carbon nanotubes (SWNTs) nanoplex
- (2014) Tommy Anderson et al. Biomaterials Science
- Hypoxia-responsive polymeric nanoparticles for tumor-targeted drug delivery
- (2013) Thavasyappan Thambi et al. BIOMATERIALS
- Potent inhibition of DOT1L as treatment of MLL-fusion leukemia
- (2013) S. R. Daigle et al. BLOOD
- Efficacy of decitabine-loaded nanogels in overcoming cancer drug resistance is mediated via sustained DNA methyltransferase 1 (DNMT1) depletion
- (2013) Sivakumar Vijayaraghavalu et al. CANCER LETTERS
- DNA Methylation Biomarkers for Noninvasive Diagnosis of Colorectal Cancer
- (2013) F. J. Carmona et al. Cancer Prevention Research
- Lessons from the Cancer Genome
- (2013) Levi A. Garraway et al. CELL
- Long Noncoding RNAs: Cellular Address Codes in Development and Disease
- (2013) Pedro J. Batista et al. CELL
- The role of genetics in the establishment and maintenance of the epigenome
- (2013) Covadonga Huidobro et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Design of pH responsive clickable prodrugs applied to histone deacetylase inhibitors: A new strategy for anticancer therapy
- (2013) Régis Delatouche et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- A double take on bivalent promoters
- (2013) P. Voigt et al. GENES & DEVELOPMENT
- Metabolism, mechanism of action and sensitivity profile of fluorocyclopentenylcytosine (RX-3117; TV-1360)
- (2013) Godefridus J. Peters et al. INVESTIGATIONAL NEW DRUGS
- DNA Methylation Signatures Identify Biologically Distinct Thyroid Cancer Subtypes
- (2013) Sandra Rodríguez-Rodero et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- DNA methylation: roles in mammalian development
- (2013) Zachary D. Smith et al. NATURE REVIEWS GENETICS
- How is epigenetic information maintained through DNA replication?
- (2013) Varija N Budhavarapu et al. Epigenetics & Chromatin
- Epigenetics advancing personalized nanomedicine in cancer therapy
- (2012) Shujun Liu ADVANCED DRUG DELIVERY REVIEWS
- Functionalization of single-walled carbon nanotubes enables efficient intracellular delivery of siRNA targeting MDM2 to inhibit breast cancer cells growth
- (2012) Hailong Chen et al. BIOMEDICINE & PHARMACOTHERAPY
- Cancer Genetics and Epigenetics: Two Sides of the Same Coin?
- (2012) Jueng Soo You et al. CANCER CELL
- Dynamics and Memory of Heterochromatin in Living Cells
- (2012) Nathaniel A. Hathaway et al. CELL
- Histone phosphorylation
- (2012) Dorine Rossetto et al. Epigenetics
- BRCA1epigenetic inactivation predicts sensitivity to platinum-based chemotherapy in breast and ovarian cancer
- (2012) Olafur A. Stefansson et al. Epigenetics
- Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery
- (2012) Hyukjin Lee et al. Nature Nanotechnology
- DNA methylation profiling in the clinic: applications and challenges
- (2012) Holger Heyn et al. NATURE REVIEWS GENETICS
- Epigenetics and the environment: emerging patterns and implications
- (2012) Robert Feil et al. NATURE REVIEWS GENETICS
- Ionizing Radiation Induces Stemness in Cancer Cells
- (2012) Laura Ghisolfi et al. PLoS One
- The transferrin receptor and the targeted delivery of therapeutic agents against cancer
- (2011) Tracy R. Daniels et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Epigenetic inheritance: Uncontested?
- (2011) Bing Zhu et al. CELL RESEARCH
- Epigenetic modifications in cancer
- (2011) R Kanwal et al. CLINICAL GENETICS
- A DNA methylation fingerprint of 1628 human samples
- (2011) A. F. Fernandez et al. GENOME RESEARCH
- Landscape of TET2 mutations in acute myeloid leukemia
- (2011) S Weissmann et al. LEUKEMIA
- Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma
- (2011) Ryan D. Morin et al. NATURE
- Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes
- (2011) Lydia Alvarez-Erviti et al. NATURE BIOTECHNOLOGY
- Cancer epigenetics reaches mainstream oncology
- (2011) Manuel Rodríguez-Paredes et al. NATURE MEDICINE
- Non-coding RNAs in human disease
- (2011) Manel Esteller NATURE REVIEWS GENETICS
- Newly Engineered Magnetic Erythrocytes for Sustained and Targeted Delivery of Anti-Cancer Therapeutic Compounds
- (2011) Caterina Cinti et al. PLoS One
- Combination Epigenetic Therapy Has Efficacy in Patients with Refractory Advanced Non-Small Cell Lung Cancer
- (2011) R. A. Juergens et al. Cancer Discovery
- Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic Differentiation
- (2010) Maria E. Figueroa et al. CANCER CELL
- microRNA Signature and Expression of Dicer and Drosha Can Predict Prognosis and Delineate Risk Groups in Neuroblastoma
- (2010) R.-J. Lin et al. CANCER RESEARCH
- DNA methylation profiling in doxorubicin treated primary locally advanced breast tumours identifies novel genes associated with survival and treatment response
- (2010) Emelyne Dejeux et al. Molecular Cancer
- Delivery of 5-Azacytidine to Human Cancer Cells by Elaidic Acid Esterification Increases Therapeutic Drug Efficacy
- (2010) B. Brueckner et al. MOLECULAR CANCER THERAPEUTICS
- Receptor-targeted nanocarriers for therapeutic delivery to cancer
- (2010) Bo Yu et al. MOLECULAR MEMBRANE BIOLOGY
- Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes
- (2010) Gillian L. Dalgliesh et al. NATURE
- MicroRNAs in Cancer
- (2009) Ramiro Garzon et al. Annual Review of Medicine
- MicroRNA 29b functions in acute myeloid leukemia
- (2009) R. Garzon et al. BLOOD
- Histone deacetylase inhibitor prodrugs in nanoparticle vector enhanced gene expression in human cancer cells
- (2009) Yuta Ishii et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Beyond Trastuzumab: Small Molecule Tyrosine Kinase Inhibitors in HER-2-Positive Breast Cancer
- (2009) V. Roy et al. ONCOLOGIST
- Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1
- (2009) M. Tahiliani et al. SCIENCE
- A piRNA Pathway Primed by Individual Transposons Is Linked to De Novo DNA Methylation in Mice
- (2008) Alexei A. Aravin et al. MOLECULAR CELL
- Dicer, Drosha, and Outcomes in Patients with Ovarian Cancer
- (2008) William M. Merritt et al. NEW ENGLAND JOURNAL OF MEDICINE
- Epigenetics in Cancer
- (2008) Manel Esteller NEW ENGLAND JOURNAL OF MEDICINE
- A microRNA DNA methylation signature for human cancer metastasis
- (2008) A. Lujambio et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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