Innate immune memory: a paradigm shift in understanding host defense

Cytomegalovirus Infection Drives Adaptive Epigenetic Diversification of NK Cells with Altered Signaling and Effector Function

(2015) Heinrich Schlums et al.   IMMUNITY

Epigenetic Modification and Antibody-Dependent Expansion of Memory-like NK Cells in Human Cytomegalovirus-Infected Individuals

(2015) Jaewon Lee et al.   IMMUNITY

The biology of innate lymphoid cells

(2015) David Artis et al.   NATURE

Heterologous Immunological Effects of Early BCG Vaccination in Low-Birth-Weight Infants in Guinea-Bissau: A Randomized-controlled Trial

(2014) Kristoffer Jarlov Jensen et al.   JOURNAL OF INFECTIOUS DISEASES

Neutrophils prime a long-lived effector macrophage phenotype that mediates accelerated helminth expulsion

(2014) Fei Chen et al.   NATURE IMMUNOLOGY

Autophagy Controls BCG-Induced Trained Immunity and the Response to Intravesical BCG Therapy for Bladder Cancer

(2014) Kathrin Buffen et al.   PLoS Pathogens

Detection of a TLR2 agonist by hematopoietic stem and progenitor cells impacts the function of the macrophages they produce

(2013) Alberto Yáñez et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Succinate is an inflammatory signal that induces IL-1β through HIF-1α

(2013) G. M. Tannahill et al.   NATURE

High-density lipoprotein mediates anti-inflammatory reprogramming of macrophages via the transcriptional regulator ATF3

(2013) Dominic De Nardo et al.   NATURE IMMUNOLOGY

Innate immune memory: implications for development of pediatric immunomodulatory agents and adjuvanted vaccines

(2013) Ofer Levy et al.   PEDIATRIC RESEARCH

A Role for SIRT2-Dependent Histone H3K18 Deacetylation in Bacterial Infection

(2013) H. A. Eskandarian et al.   SCIENCE

A small jab – a big effect: nonspecific immunomodulation by vaccines

(2013) Christine S. Benn et al.   TRENDS IN IMMUNOLOGY

Epigenetics and Bacterial Infections

(2013) H. Bierne et al.   Cold Spring Harbor Perspectives in Medicine

Daddy Issues: Paternal Effects on Phenotype

(2012) Oliver J. Rando   CELL

NAD+-dependent Sirtuin 1 and 6 Proteins Coordinate a Switch from Glucose to Fatty Acid Oxidation during the Acute Inflammatory Response

(2012) Tie Fu Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Trained Immunity: A Memory for Innate Host Defense

(2011) Mihai G. Netea et al.   Cell Host & Microbe

Systems biology of vaccination for seasonal influenza in humans

(2011) Helder I Nakaya et al.   NATURE IMMUNOLOGY

Identification and functions of pattern-recognition receptors

(2010) Yutaro Kumagai et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Hemocyte Differentiation Mediates Innate Immune Memory in Anopheles gambiae Mosquitoes

(2010) Janneth Rodrigues et al.   SCIENCE

Adaptive immune features of natural killer cells

(2009) Joseph C. Sun et al.   NATURE