标题
Anti-colony-stimulating factor therapies for inflammatory and autoimmune diseases
作者
关键词
-
出版物
NATURE REVIEWS DRUG DISCOVERY
Volume 16, Issue 1, Pages 53-70
出版商
Springer Nature
发表日期
2016-12-29
DOI
10.1038/nrd.2016.231
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- G-CSF and Neutrophils Are Nonredundant Mediators of Murine Experimental Autoimmune Uveoretinitis
- (2016) Gabrielle L. Goldberg et al. AMERICAN JOURNAL OF PATHOLOGY
- Macrophage colony-stimulating factor (CSF1) controls monocyte production and maturation and the steady-state size of the liver in pigs
- (2016) Kristin A. Sauter et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Pharmacological targeting of CSF1R inhibits microglial proliferation and prevents the progression of Alzheimer’s-like pathology
- (2016) Adrian Olmos-Alonso et al. BRAIN
- Protective role of G-CSF in dextran sulfate sodium-induced acute colitis through generating gut-homing macrophages
- (2016) Shahab Meshkibaf et al. CYTOKINE
- Granulocyte colony-stimulating factor (G-CSF) plays an important role in immune complex-mediated arthritis
- (2016) Anne D. Christensen et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Pathogenic IL-23 signaling is required to initiate GM-CSF-driven autoimmune myocarditis in mice
- (2016) Lei Wu et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Tissue-Resident Macrophage Ontogeny and Homeostasis
- (2016) Florent Ginhoux et al. IMMUNITY
- Granulocyte macrophage colony-stimulating factor induces CCL17 production via IRF4 to mediate inflammation
- (2016) Adrian Achuthan et al. JOURNAL OF CLINICAL INVESTIGATION
- Therapeutic Targeting of the G-CSF Receptor Reduces Neutrophil Trafficking and Joint Inflammation in Antibody-Mediated Inflammatory Arthritis
- (2016) Ian K. Campbell et al. JOURNAL OF IMMUNOLOGY
- Cell-Surface and Secreted Isoforms of CSF-1 Exert Opposing Roles in Macrophage-Mediated Neural Damage in Cx32-Deficient Mice
- (2016) J. Groh et al. JOURNAL OF NEUROSCIENCE
- GM-CSF Enhances Macrophage Glycolytic Activity In Vitro and Improves Detection of Inflammation In Vivo
- (2016) P. Singh et al. JOURNAL OF NUCLEAR MEDICINE
- CD45 regulates GM-CSF, retinoic acid and T-cell homing in intestinal inflammation
- (2016) A Samarakoon et al. Mucosal Immunology
- Conformational Changes in the GM-CSF Receptor Suggest a Molecular Mechanism for Affinity Conversion and Receptor Signaling
- (2016) Sophie E. Broughton et al. STRUCTURE
- Emerging Roles for CSF-1 Receptor and its Ligands in the Nervous System
- (2016) Violeta Chitu et al. TRENDS IN NEUROSCIENCES
- Phase 2, randomised placebo-controlled trial to evaluate the efficacy and safety of an anti-GM-CSF antibody (KB003) in patients with inadequately controlled asthma
- (2016) Nestor A Molfino et al. BMJ Open
- Macrophage-Colony Stimulating Factor Derived from Injured Primary Afferent Induces Proliferation of Spinal Microglia and Neuropathic Pain in Rats
- (2016) Masamichi Okubo et al. PLoS One
- OP0022 Juvenile Idiopathic Arthritis in Adulthood: Clinical Pattern and Long-Term Outcomes of 512 Patients
- (2015) F. Oliveira Ramos et al. ANNALS OF THE RHEUMATIC DISEASES
- Synovial CD4+ T-cell-derived GM-CSF supports the differentiation of an inflammatory dendritic cell population in rheumatoid arthritis
- (2015) G Reynolds et al. ANNALS OF THE RHEUMATIC DISEASES
- FRI0167 Patient-Reported Outcomes (PROS) During Treatment with Mavrilimumab, A Fully Human Monoclonal Antibody Targeting GM–CSFR-Alpha, In the Phase IIB Earth Explorer 1 Study
- (2015) J.M. Kremer et al. ANNALS OF THE RHEUMATIC DISEASES
- NADPH oxidase controls neutrophilic response to sterile inflammation in mice by regulating the IL-1 /G-CSF axis
- (2015) J. Bagaitkar et al. BLOOD
- slan-defined subsets of CD16-positive monocytes: impact of granulomatous inflammation and M-CSF receptor mutation
- (2015) T. P. Hofer et al. BLOOD
- Administration of granulocyte-colony stimulating factor accompanied with a balanced diet improves cardiac function alterations induced by high fat diet in mice
- (2015) Pâmela Santana Daltro et al. BMC Cardiovascular Disorders
- Targeting the colony stimulating factor 1 receptor alleviates two forms of Charcot–Marie–Tooth disease in mice
- (2015) Dennis Klein et al. BRAIN
- Neutrophils: important contributors to tumor progression and metastasis
- (2015) Agnieszka Swierczak et al. CANCER AND METASTASIS REVIEWS
- Monoclonal antibody against macrophage colony-stimulating factor suppresses circulating monocytes and tissue macrophage function but does not alter cell infiltration/activation in cutaneous lesions or clinical outcomes in patients with cutaneous lupus ery
- (2015) K. Masek-Hammerman et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- Neutrophil functions in morbidly obese subjects
- (2015) E. Brotfain et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- The βc receptor family – Structural insights and their functional implications
- (2015) Sophie E. Broughton et al. CYTOKINE
- GM-CSF: An immune modulatory cytokine that can suppress autoimmunity
- (2015) Palash Bhattacharya et al. CYTOKINE
- IL-12-polarized Th1 cells produce GM-CSF and induce EAE independent of IL-23
- (2015) Heather M. Grifka-Walk et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- GM-CSF promotes migration of human monocytes across the blood brain barrier
- (2015) Daphne Y. S. Vogel et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Granulocyte-colony stimulating factor (G-CSF)-induced mechanical hyperalgesia in mice: Role for peripheral TNFα, IL-1β and IL-10
- (2015) Thacyana T. Carvalho et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- GM-CSF as a target in inflammatory/autoimmune disease: current evidence and future therapeutic potential
- (2015) John A Hamilton Expert Review of Clinical Immunology
- CSF1 Restores Innate Immunity After Liver Injury in Mice and Serum Levels Indicate Outcomes of Patients With Acute Liver Failure
- (2015) Benjamin M. Stutchfield et al. GASTROENTEROLOGY
- Granulocyte Macrophage Colony-Stimulating Factor-Activated Eosinophils Promote Interleukin-23 Driven Chronic Colitis
- (2015) Thibault Griseri et al. IMMUNITY
- The Cytokine GM-CSF Drives the Inflammatory Signature of CCR2+ Monocytes and Licenses Autoimmunity
- (2015) Andrew L. Croxford et al. IMMUNITY
- GM-CSF Mouse Bone Marrow Cultures Comprise a Heterogeneous Population of CD11c+MHCII+ Macrophages and Dendritic Cells
- (2015) Julie Helft et al. IMMUNITY
- GM-CSF and uPA are required for Porphyromonas gingivalis -induced alveolar bone loss in a mouse periodontitis model
- (2015) Roselind S Lam et al. IMMUNOLOGY AND CELL BIOLOGY
- Innate response activator B cells: origins and functions: Fig. 1.
- (2015) Benjamin G. Chousterman et al. INTERNATIONAL IMMUNOLOGY
- Macrophage depletion ameliorates nephritis induced by pathogenic antibodies
- (2015) Samantha A. Chalmers et al. JOURNAL OF AUTOIMMUNITY
- Neutrophil-related factors as biomarkers in EAE and MS
- (2015) Julie M. Rumble et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Unique and redundant functions of NKp46+ILC3s in models of intestinal inflammation
- (2015) Christina Song et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Specific Contributions of CSF-1 and GM-CSF to the Dynamics of the Mononuclear Phagocyte System
- (2015) Cynthia Louis et al. JOURNAL OF IMMUNOLOGY
- Th Cell Diversity in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis
- (2015) Kevin S. Carbajal et al. JOURNAL OF IMMUNOLOGY
- IL-3 Maintains Activation of the p90S6K/RPS6 Pathway and Increases Translation in Human Eosinophils
- (2015) Stephane Esnault et al. JOURNAL OF IMMUNOLOGY
- Technical Advance: Transcription factor, promoter, and enhancer utilization in human myeloid cells
- (2015) Anagha Joshi et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Granulocyte-Macrophage Colony Stimulating Factor Exerts Protective and Immunomodulatory Effects in Cortical Trauma
- (2015) Matthew L. Kelso et al. JOURNAL OF NEUROIMMUNOLOGY
- Colony-stimulating factor 1 receptor inhibition prevents microglial plaque association and improves cognition in 3xTg-AD mice
- (2015) Nabil N. Dagher et al. Journal of Neuroinflammation
- Results from a Phase IIA Parallel Group Study of JNJ-40346527, an Oral CSF-1R Inhibitor, in Patients with Active Rheumatoid Arthritis despite Disease-modifying Antirheumatic Drug Therapy
- (2015) M. C. Genovese et al. JOURNAL OF RHEUMATOLOGY
- IL-3 contributes to development of lupus nephritis in MRL/Ipr mice
- (2015) Kerstin Renner et al. KIDNEY INTERNATIONAL
- Proximal tubule-derived colony stimulating factor-1 mediates polarization of renal macrophages and dendritic cells, and recovery in acute kidney injury
- (2015) Yinqiu Wang et al. KIDNEY INTERNATIONAL
- CSL311, a novel, potent, therapeutic monoclonal antibody for the treatment of diseases mediated by the common β chain of the IL-3, GM-CSF and IL-5 receptors
- (2015) Con Panousis et al. mAbs
- IL-17-producing γδ T cells and neutrophils conspire to promote breast cancer metastasis
- (2015) Seth B. Coffelt et al. NATURE
- Injured sensory neuron–derived CSF1 induces microglial proliferation and DAP12-dependent pain
- (2015) Zhonghui Guan et al. NATURE NEUROSCIENCE
- Targeting GM-CSF in inflammatory diseases
- (2015) Ian P. Wicks et al. Nature Reviews Rheumatology
- Orally administered colony stimulating factor 1 receptor inhibitor PLX3397 in recurrent glioblastoma: an Ivy Foundation Early Phase Clinical Trials Consortium phase II study
- (2015) Nicholas Butowski et al. NEURO-ONCOLOGY
- Phenotypic characterization of a Csf1r haploinsufficient mouse model of adult-onset leukodystrophy with axonal spheroids and pigmented glia (ALSP)
- (2015) Violeta Chitu et al. NEUROBIOLOGY OF DISEASE
- Intra-articular administration of an antibody against CSF-1 receptor reduces pain-related behaviors and inflammation in CFA-induced knee arthritis
- (2015) P.A. Alvarado-Vazquez et al. NEUROSCIENCE LETTERS
- Structure-Guided Blockade of CSF1R Kinase in Tenosynovial Giant-Cell Tumor
- (2015) William D. Tap et al. NEW ENGLAND JOURNAL OF MEDICINE
- Systemic and Cardiac Depletion of M2 Macrophage through CSF-1R Signaling Inhibition Alters Cardiac Function Post Myocardial Infarction
- (2015) Anne-Laure Leblond et al. PLoS One
- Increased IL-3 serum levels in chronic patients with schizophrenia: Associated with psychopathology
- (2015) Mei Hong Xiu et al. PSYCHIATRY RESEARCH
- Interleukin-3 amplifies acute inflammation and is a potential therapeutic target in sepsis
- (2015) G. F. Weber et al. SCIENCE
- Proinflammatory GM-CSF–producing B cells in multiple sclerosis and B cell depletion therapy
- (2015) Rui Li et al. Science Translational Medicine
- Functional inflammatory profiles distinguish myelin-reactive T cells from patients with multiple sclerosis
- (2015) Yonghao Cao et al. Science Translational Medicine
- Structure and Assembly Mechanism of the Signaling Complex Mediated by Human CSF-1
- (2015) Jan Felix et al. STRUCTURE
- Complementary action of granulocyte macrophage colony-stimulating factor and interleukin-17A induces interleukin-23, receptor activator of nuclear factor-κB ligand, and matrix metalloproteinases and drives bone and cartilage pathology in experimental arthritis: rationale for combination therapy in rheumatoid arthritis
- (2015) Annemarie E. M. van Nieuwenhuijze et al. ARTHRITIS RESEARCH & THERAPY
- Granulocyte macrophage colony-stimulating factor is required for aortic dissection/intramural haematoma
- (2015) Bo-Kyung Son et al. Nature Communications
- Neutralization and clearance of GM-CSF by autoantibodies in pulmonary alveolar proteinosis
- (2015) Luca Piccoli et al. Nature Communications
- Adult-Onset Leukoencephalopathy with Axonal Spheroids and Pigmented Glia Caused by a Novel R782G Mutation in CSF1R
- (2015) Nicola Foulds et al. Scientific Reports
- MOR103, a human monoclonal antibody to granulocyte–macrophage colony-stimulating factor, in the treatment of patients with moderate rheumatoid arthritis: results of a phase Ib/IIa randomised, double-blind, placebo-controlled, dose-escalation trial
- (2014) Frank Behrens et al. ANNALS OF THE RHEUMATIC DISEASES
- Preclinical characterisation of the GM-CSF receptor as a therapeutic target in rheumatoid arthritis
- (2014) D E A Greven et al. ANNALS OF THE RHEUMATIC DISEASES
- Crystal structure of the mouse interleukin-3 β-receptor: insights into interleukin-3 binding and receptor activation
- (2014) Paul D. Carr et al. BIOCHEMICAL JOURNAL
- Activity of SL-401, a targeted therapy directed to interleukin-3 receptor, in blastic plasmacytoid dendritic cell neoplasm patients
- (2014) A. E. Frankel et al. BLOOD
- Early start and stop of biologics: has the time come?
- (2014) Ronald F van Vollenhoven et al. BMC Medicine
- CD123, the plasmacytoid dendritic cell phenotypic marker, is abundant in leprosy type 1 reaction
- (2014) P.R. Andrade et al. BRITISH JOURNAL OF DERMATOLOGY
- Targeting Tumor-Associated Macrophages with Anti-CSF-1R Antibody Reveals a Strategy for Cancer Therapy
- (2014) Carola H. Ries et al. CANCER CELL
- Crosstalk between Muscularis Macrophages and Enteric Neurons Regulates Gastrointestinal Motility
- (2014) Paul Andrew Muller et al. CELL
- STAT5 programs a distinct subset of GM-CSF-producing T helper cells that is essential for autoimmune neuroinflammation
- (2014) Wanqiang Sheng et al. CELL RESEARCH
- Innate Response Activator B Cells Aggravate Atherosclerosis by Stimulating T Helper-1 Adaptive Immunity
- (2014) Ingo Hilgendorf et al. CIRCULATION
- Targeting IL-34 in chronic inflammation
- (2014) Emma L. Masteller et al. DRUG DISCOVERY TODAY
- Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines
- (2014) Peter J. Murray et al. IMMUNITY
- CSF-1–dependant donor-derived macrophages mediate chronic graft-versus-host disease
- (2014) Kylie A. Alexander et al. JOURNAL OF CLINICAL INVESTIGATION
- Pleural innate response activator B cells protect against pneumonia via a GM-CSF-IgM axis
- (2014) Georg F. Weber et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The IL-3/IL-5/GM-CSF Common Receptor Plays a Pivotal Role in the Regulation of Th2 Immunity and Allergic Airway Inflammation
- (2014) K. L. Asquith et al. JOURNAL OF IMMUNOLOGY
- IL-3 Inhibits TNF- -Induced Bone Resorption and Prevents Inflammatory Arthritis
- (2014) S. D. Yogesha et al. JOURNAL OF IMMUNOLOGY
- GM-CSF but Not IL-17 Is Critical for the Development of Severe Interstitial Lung Disease in SKG Mice
- (2014) Aoi Shiomi et al. JOURNAL OF IMMUNOLOGY
- GM-CSF-Responsive Monocyte-Derived Dendritic Cells Are Pivotal in Th17 Pathogenesis
- (2014) H.-J. Ko et al. JOURNAL OF IMMUNOLOGY
- Analysis of the transcriptional networks underpinning the activation of murine macrophages by inflammatory mediators
- (2014) S. Raza et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Pleiotropic effects of extended blockade of CSF1R signaling in adult mice
- (2014) K. A. Sauter et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Macrophages from the synovium of active rheumatoid arthritis exhibit an activin A-dependent pro-inflammatory profile
- (2014) Blanca Soler Palacios et al. JOURNAL OF PATHOLOGY
- Colony-Stimulating Factor-1: A Potential Biomarker for Lupus Nephritis
- (2014) J. Menke et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- GM-CSF Promotes Macrophage Alternative Activation after Renal Ischemia/Reperfusion Injury
- (2014) S. C. Huen et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Targeting of acute myeloid leukemia in vitro and in vivo with an anti-CD123 mAb engineered for optimal ADCC
- (2014) S J Busfield et al. LEUKEMIA
- A Phase 1 study of the safety, pharmacokinetics and anti-leukemic activity of the anti-CD123 monoclonal antibody CSL360 in relapsed, refractory or high-risk acute myeloid leukemia
- (2014) Simon Z. He et al. LEUKEMIA & LYMPHOMA
- Efficacy and safety of mavrilimumab in Japanese subjects with rheumatoid arthritis: Findings from a Phase IIa study
- (2014) Tsutomu Takeuchi et al. Modern Rheumatology
- 2-(Trimethylammonium) Ethyl (R)-3-Methoxy-3-oxo-2-Stearamidopropyl Phosphate Suppresses Osteoclast Maturation and Bone Resorption by Targeting Macrophage-Colony Stimulating Factor Signaling
- (2014) So Jeong Park et al. MOLECULES AND CELLS
- Innate lymphoid cells integrate stromal and immunological signals to enhance antibody production by splenic marginal zone B cells
- (2014) Giuliana Magri et al. NATURE IMMUNOLOGY
- The multifactorial role of neutrophils in rheumatoid arthritis
- (2014) Helen L. Wright et al. Nature Reviews Rheumatology
- Critical Role of the GM-CSF Signaling Pathway in Macrophage Pro-Repair Activities
- (2014) Eric Bernasconi et al. PATHOBIOLOGY
- The Closely Related CD103+ Dendritic Cells (DCs) and Lymphoid-Resident CD8+ DCs Differ in Their Inflammatory Functions
- (2014) Zhijun Jiao et al. PLoS One
- A GM-CSF/IL-33 Pathway Facilitates Allergic Airway Responses to Sub-Threshold House Dust Mite Exposure
- (2014) Alba Llop-Guevara et al. PLoS One
- IL-17 and GM-CSF Expression Are Antagonistically Regulated by Human T Helper Cells
- (2014) R. Noster et al. Science Translational Medicine
- Homeostasis in the mononuclear phagocyte system
- (2014) Stephen J. Jenkins et al. TRENDS IN IMMUNOLOGY
- CSF-1 Receptor Signaling in Myeloid Cells
- (2014) E. R. Stanley et al. Cold Spring Harbor Perspectives in Biology
- Fc gamma receptor-TLR cross-talk elicits pro-inflammatory cytokine production by human M2 macrophages
- (2014) Lisa T. C. Vogelpoel et al. Nature Communications
- Dual Mechanism of Interleukin-3 Receptor Blockade by an Anti-Cancer Antibody
- (2014) Sophie E. Broughton et al. Cell Reports
- Bone- and Cartilage-Protective Effects of a Monoclonal Antibody Against Colony-Stimulating Factor 1 Receptor in Experimental Arthritis
- (2014) Myew-Ling Toh et al. Arthritis & Rheumatology
- Brief Report: T Cell Expression of Granulocyte-Macrophage Colony-Stimulating Factor in Juvenile Arthritis Is Contingent Upon Th17 Plasticity
- (2014) Christopher Piper et al. Arthritis & Rheumatology
- The Promotion of Breast Cancer Metastasis Caused by Inhibition of CSF-1R/CSF-1 Signaling Is Blocked by Targeting the G-CSF Receptor
- (2014) A. Swierczak et al. Cancer Immunology Research
- Breaking the vicious cycle between breast cancer cells and tumor-associated macrophages
- (2014) Shicheng Su et al. OncoImmunology
- Transgenic Expression of GM-CSF in T Cells Causes Disseminated Histiocytosis
- (2013) Annemarie E. van Nieuwenhuijze et al. AMERICAN JOURNAL OF PATHOLOGY
- Signalling by the βc family of cytokines
- (2013) Timothy R. Hercus et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Receptor-type Protein-tyrosine Phosphatase ζ Is a Functional Receptor for Interleukin-34
- (2013) Sayan Nandi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Colony-stimulating factor 1 receptor (CSF1R) signaling in injured neurons facilitates protection and survival
- (2013) Jian Luo et al. JOURNAL OF EXPERIMENTAL MEDICINE
- IL-4 directly signals tissue-resident macrophages to proliferate beyond homeostatic levels controlled by CSF-1
- (2013) Stephen J. Jenkins et al. JOURNAL OF EXPERIMENTAL MEDICINE
- GM-CSF Produced by Nonhematopoietic Cells Is Required for Early Epithelial Cell Proliferation and Repair of Injured Colonic Mucosa
- (2013) L. Egea et al. JOURNAL OF IMMUNOLOGY
- Regulation of Microglial Proliferation during Chronic Neurodegeneration
- (2013) D. Gomez-Nicola et al. JOURNAL OF NEUROSCIENCE
- Distinct roles of CSF family cytokines in macrophage infiltration and activation in glioma progression and injury response
- (2013) Malgorzata Sielska et al. JOURNAL OF PATHOLOGY
- Transcriptional Mechanisms Underlying Sensitization of Peripheral Sensory Neurons by Granulocyte-/Granulocyte-Macrophage Colony Stimulating Factors
- (2013) Kiran Kumar Bali et al. Molecular Pain
- M-CSF instructs myeloid lineage fate in single haematopoietic stem cells
- (2013) Noushine Mossadegh-Keller et al. NATURE
- CSF1R mutations link POLD and HDLS as a single disease entity
- (2013) A. M. Nicholson et al. NEUROLOGY
- Distinct bone marrow-derived and tissue-resident macrophage lineages proliferate at key stages during inflammation
- (2013) Luke C. Davies et al. Nature Communications
- Granulocyte-macrophage colony-stimulating factor is a key mediator in inflammatory and arthritic pain
- (2012) Andrew D Cook et al. ANNALS OF THE RHEUMATIC DISEASES
- Efficacy and safety of mavrilimumab in subjects with rheumatoid arthritis
- (2012) Gerd R Burmester et al. ANNALS OF THE RHEUMATIC DISEASES
- The mechanism of shared but distinct CSF-1R signaling by the non-homologous cytokines IL-34 and CSF-1
- (2012) Heli Liu et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Regulation of dendritic cell development by GM-CSF: molecular control and implications for immune homeostasis and therapy
- (2012) L. van de Laar et al. BLOOD
- Steady-state neutrophil homeostasis is dependent on TLR4/TRIF signaling
- (2012) S. Bugl et al. BLOOD
- Monoclonal antibodies against macrophage colony-stimulating factor diminish the number of circulating intermediate and nonclassical (CD14++CD16+/CD14+CD16++) monocytes in rheumatoid arthritis patient
- (2012) M. Korkosz et al. BLOOD
- Intravenous administration of granulocyte colony-stimulating factor for treating neuropathic pain associated with compression myelopathy: a phase I and IIa clinical trial
- (2012) Kei Kato et al. EUROPEAN SPINE JOURNAL
- GM-CSF Controls Nonlymphoid Tissue Dendritic Cell Homeostasis but Is Dispensable for the Differentiation of Inflammatory Dendritic Cells
- (2012) Melanie Greter et al. IMMUNITY
- Dysregulated Hematopoietic Stem and Progenitor Cell Activity Promotes Interleukin-23-Driven Chronic Intestinal Inflammation
- (2012) Thibault Griseri et al. IMMUNITY
- The GM-CSF/IL-3/IL-5 cytokine receptor family: from ligand recognition to initiation of signaling
- (2012) Sophie E. Broughton et al. IMMUNOLOGICAL REVIEWS
- CSF-1 signaling mediates recovery from acute kidney injury
- (2012) Ming-Zhi Zhang et al. JOURNAL OF CLINICAL INVESTIGATION
- Interleukin-1α controls allergic sensitization to inhaled house dust mite via the epithelial release of GM-CSF and IL-33
- (2012) Monique A.M. Willart et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Defining GM-CSF- and Macrophage-CSF-Dependent Macrophage Responses by In Vitro Models
- (2012) D. C. Lacey et al. JOURNAL OF IMMUNOLOGY
- Distribution of granulocyte–monocyte colony-stimulating factor and its receptor α-subunit in the adult human brain with specific reference to Alzheimer’s disease
- (2012) Sami Ridwan et al. JOURNAL OF NEURAL TRANSMISSION
- Early Systemic Granulocyte-Colony Stimulating Factor Treatment Attenuates Neuropathic Pain after Peripheral Nerve Injury
- (2012) Po-Kuan Chao et al. PLoS One
- Hypoxia Enhances the Proliferative Response of Macrophages to CSF-1 and Their Pro-Survival Response to TNF
- (2012) John A. Hamilton et al. PLoS One
- The Interleukin 3 Gene (IL3) Contributes to Human Brain Volume Variation by Regulating Proliferation and Survival of Neural Progenitors
- (2012) Xiong-jian Luo et al. PLoS One
- Innate Response Activator B Cells Protect Against Microbial Sepsis
- (2012) P. J. Rauch et al. SCIENCE
- The CSF-1 receptor fashions the intestinal stem cell niche
- (2012) Dilara Akcora et al. Stem Cell Research
- Structural Basis for the Dual Recognition of Helical Cytokines IL-34 and CSF-1 by CSF-1R
- (2012) Xiaolei Ma et al. STRUCTURE
- Colony stimulating factors and myeloid cell biology in health and disease
- (2012) John A. Hamilton et al. TRENDS IN IMMUNOLOGY
- Granulocyte-macrophage colony-stimulating factor is a key mediator in experimental osteoarthritis pain and disease development
- (2012) Andrew D Cook et al. ARTHRITIS RESEARCH & THERAPY
- Mavrilimumab, a human monoclonal antibody targeting GM-CSF receptor- , in subjects with rheumatoid arthritis: a randomised, double-blind, placebo-controlled, phase I, first-in-human study
- (2011) G. R. Burmester et al. ANNALS OF THE RHEUMATIC DISEASES
- Therapeutic applications of macrophage colony-stimulating factor-1 (CSF-1) and antagonists of CSF-1 receptor (CSF-1R) signaling
- (2011) D. A. Hume et al. BLOOD
- GM-CSF is not essential for optimal fertility or for weight control
- (2011) John A. Hamilton et al. CYTOKINE
- GM-CSF increases cross-presentation and CD103 expression by mouse CD8+ spleen dendritic cells
- (2011) Yifan Zhan et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- A quantifiable proliferative burst of tissue macrophages restores homeostatic macrophage populations after acute inflammation
- (2011) Luke C. Davies et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Control of macrophage lineage populations by CSF-1 receptor and GM-CSF in homeostasis and inflammation
- (2011) Jason C Lenzo et al. IMMUNOLOGY AND CELL BIOLOGY
- Pretransplant CSF-1 therapy expands recipient macrophages and ameliorates GVHD after allogeneic hematopoietic cell transplantation
- (2011) Daigo Hashimoto et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Differentiation of Inflammatory Dendritic Cells Is Mediated by NF- B1-Dependent GM-CSF Production in CD4 T Cells
- (2011) I. K. Campbell et al. JOURNAL OF IMMUNOLOGY
- IL-3 Attenuates Collagen-Induced Arthritis by Modulating the Development of Foxp3+ Regulatory T Cells
- (2011) R. K. Srivastava et al. JOURNAL OF IMMUNOLOGY
- Granulocyte-macrophage colony-stimulating factor (GM-CSF): a chemoattractive agent for murine leukocytes in vivo
- (2011) Maitham Khajah et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Mutations in the colony stimulating factor 1 receptor (CSF1R) gene cause hereditary diffuse leukoencephalopathy with spheroids
- (2011) Rosa Rademakers et al. NATURE GENETICS
- IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses
- (2011) Thomas Krausgruber et al. NATURE IMMUNOLOGY
- RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation
- (2011) Laura Codarri et al. NATURE IMMUNOLOGY
- The encephalitogenicity of TH17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF
- (2011) Mohamed El-Behi et al. NATURE IMMUNOLOGY
- Granulocyte-Colony Stimulating Factor (G-CSF) induces mechanical hyperalgesia via spinal activation of MAP kinases and PI3K in mice
- (2011) Thacyana T. Carvalho et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Batf3-Dependent CD11blow/− Peripheral Dendritic Cells Are GM-CSF-Independent and Are Not Required for Th Cell Priming after Subcutaneous Immunization
- (2011) Brian T. Edelson et al. PLoS One
- Absence of Colony Stimulation Factor-1 Receptor Results in Loss of Microglia, Disrupted Brain Development and Olfactory Deficits
- (2011) Bryna Erblich et al. PLoS One
- Local Macrophage Proliferation, Rather than Recruitment from the Blood, Is a Signature of TH2 Inflammation
- (2011) S. J. Jenkins et al. SCIENCE
- The number of elevated cytokines and chemokines in preclinical seropositive rheumatoid arthritis predicts time to diagnosis in an age-dependent manner
- (2010) Kevin D. Deane et al. ARTHRITIS AND RHEUMATISM
- Systematic cytokine receptor profiling reveals GM-CSF as a novel TLR-independent activator of human plasmacytoid predendritic cells
- (2010) C. Ghirelli et al. BLOOD
- An antibody against the colony-stimulating factor 1 receptor depletes the resident subset of monocytes and tissue- and tumor-associated macrophages but does not inhibit inflammation
- (2010) K. P. A. MacDonald et al. BLOOD
- Seeing old friends from a different angle: Novel properties of hematopoietic growth factors in the healthy and diseased brain
- (2010) Kai Diederich et al. HIPPOCAMPUS
- Development and functional specialization of CD103+dendritic cells
- (2010) Maria-Luisa del Rio et al. IMMUNOLOGICAL REVIEWS
- GM-CSF–dependent, CD103+dermal dendritic cells play a critical role in Th effector cell differentiation after subcutaneous immunization
- (2010) Irah L. King et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Cutting Edge: Granulocyte-Macrophage Colony-Stimulating Factor Is the Major CD8+ T Cell-Derived Licensing Factor for Dendritic Cell Activation
- (2010) L. Min et al. JOURNAL OF IMMUNOLOGY
- Hematopoietic colony-stimulating factors: new players in tumor–nerve interactions
- (2010) Sebastian Stösser et al. JOURNAL OF MOLECULAR MEDICINE-JMM
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- (2010) Jiin-Tarng Liou et al. JOURNAL OF NEUROIMMUNOLOGY
- The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection
- (2010) Takashi Satoh et al. NATURE IMMUNOLOGY
- GM-CSF: a role in immune and inflammatory reactions in the intestine
- (2010) Laia Egea et al. Expert Review of Gastroenterology & Hepatology
- The dynamics of macrophage lineage populations in inflammatory and autoimmune diseases
- (2009) John A. Hamilton et al. ARTHRITIS AND RHEUMATISM
- Important role of interleukin-3 in the early phase of collagen-induced arthritis
- (2009) Hilke Brühl et al. ARTHRITIS AND RHEUMATISM
- Monoclonal Antibody-Mediated Targeting of CD123, IL-3 Receptor α Chain, Eliminates Human Acute Myeloid Leukemic Stem Cells
- (2009) Liqing Jin et al. Cell Stem Cell
- Colony-Stimulating Factor-1 Receptor Inhibitors for the Treatment of Cancer and Inflammatory Disease
- (2009) Sharmila Patel et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Cutting Edge: Basophils Are Transiently Recruited into the Draining Lymph Nodes during Helminth Infection via IL-3, but Infection-Induced Th2 Immunity Can Develop without Basophil Lymph Node Recruitment or IL-3
- (2009) S. Kim et al. JOURNAL OF IMMUNOLOGY
- GM-CSF- and M-CSF-dependent macrophage phenotypes display differential dependence on Type I interferon signaling
- (2009) Andrew J. Fleetwood et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Hematopoietic colony–stimulating factors mediate tumor-nerve interactions and bone cancer pain
- (2009) Matthias Schweizerhof et al. NATURE MEDICINE
- G-CSF and GM-CSF as therapeutic targets in rheumatoid arthritis
- (2009) Ann L. Cornish et al. Nature Reviews Rheumatology
- Hematopoietic Cytokines Can Instruct Lineage Choice
- (2009) M. A. Rieger et al. SCIENCE
- The role of GM-CSF in adipose tissue inflammation
- (2008) Dong-Hoon Kim et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Role of M-CSF-dependent macrophages in colitis is driven by the nature of the inflammatory stimulus
- (2008) Jean-Eric Ghia et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- A key role for G-CSF-induced neutrophil production and trafficking during inflammatory arthritis
- (2008) J. L. Eyles et al. BLOOD
- Hematopoietic cytokines
- (2008) D. Metcalf BLOOD
- The Structure of the GM-CSF Receptor Complex Reveals a Distinct Mode of Cytokine Receptor Activation
- (2008) Guido Hansen et al. CELL
- The role of granulocyte macrophage-colony-stimulating factor in acute intestinal inflammation
- (2008) Yinghua Xu et al. CELL RESEARCH
- Suppression of macrophage functions impairs skeletal muscle regeneration with severe fibrosis
- (2008) M SEGAWA et al. EXPERIMENTAL CELL RESEARCH
- GM-CSF mediates autoimmunity by enhancing IL-6–dependent Th17 cell development and survival
- (2008) Ivo Sonderegger et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Recombinant human granulocyte colony-stimulating factor reduces colonic epithelial cell apoptosis and ameliorates murine dextran sulfate sodium-induced colitis
- (2008) Tetsuji Kudo et al. SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY
- Neuroinflammation: Implications for the Pathogenesis and Molecular Diagnosis of Alzheimer's Disease
- (2007) Leonel E. Rojo et al. ARCHIVES OF MEDICAL RESEARCH
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