MST1 Regulates Neuronal Cell Death via JNK/Casp3 Signaling Pathway in HFD Mouse Brain and HT22 Cells

Procyanidin C1 Activates the Nrf2/HO-1 Signaling Pathway to Prevent Glutamate-Induced Apoptotic HT22 Cell Death

(2019) Ji Song et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Hesperetin, a Citrus Flavonoid, Attenuates LPS-Induced Neuroinflammation, Apoptosis and Memory Impairments by Modulating TLR4/NF-κB Signaling

(2019) Tahir Muhammad et al.   Nutrients

Mst1-Hippo pathway triggers breast cancer apoptosis via inducing mitochondrial fragmentation in a manner dependent on JNK–Drp1 axis

(2019) Hui Ouyang et al.   OncoTargets and Therapy

Hesperetin Confers Neuroprotection by Regulating Nrf2/TLR4/NF-κB Signaling in an Aβ Mouse Model

(2019) Muhammad Ikram et al.   MOLECULAR NEUROBIOLOGY

FcRn-Dependent Transcytosis of Monoclonal Antibody in Human Nasal Epithelial Cells In Vitro: A Prerequisite for a New Delivery Route for Therapy?

(2019) Emilie Bequignon et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Myristica fragrans Kernels Prevent Paracetamol-Induced Hepatotoxicity by Inducing Anti-Apoptotic Genes and Nrf2/HO-1 Pathway

(2019) Mohamed Dkhil et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Natural Dietary Supplementation of Curcumin Protects Mice Brains against Ethanol-Induced Oxidative Stress-Mediated Neurodegeneration and Memory Impairment via Nrf2/TLR4/RAGE Signaling

(2019) Muhammad Ikram et al.   Nutrients

Caffeine Modulates Cadmium-Induced Oxidative Stress, Neuroinflammation, and Cognitive Impairments by Regulating Nrf-2/HO-1 In Vivo and In Vitro

(2019) Amjad Khan et al.   Journal of Clinical Medicine

MST1 Suppression Reduces Early Brain Injury by Inhibiting the NF-κB/MMP-9 Pathway after Subarachnoid Hemorrhage in Mice

(2018) Jie Qu et al.   BEHAVIOURAL NEUROLOGY

PI3K/AKT/JNK/p38 signalling pathway-mediated neural apoptosis in the prefrontal cortex of mice is involved in the antidepressant-like effect of pioglitazone

(2018) Jie Li et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Pharmacological Basis for the Use of Evodiamine in Alzheimer’s Disease: Antioxidation and Antiapoptosis

(2018) Yongfeng Zhang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Soybean-Derived Phytoalexins Improve Cognitive Function through Activation of Nrf2/HO-1 Signaling Pathway

(2018) Ji Seo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Butterbur Leaves Attenuate Memory Impairment and Neuronal Cell Damage in Amyloid Beta-Induced Alzheimer’s Disease Models

(2018) Namkwon Kim et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A Proteomic Approach to Uncover Neuroprotective Mechanisms of Oleocanthal against Oxidative Stress

(2018) Laura Giusti et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Hyperglycemia-Associated Dysregulation of O-GlcNAcylation and HIF1A Reduces Anticancer Action of Metformin in Ovarian Cancer Cells (SKOV-3)

(2018) Aneta Rogalska et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Melatonin Rescue Oxidative Stress-Mediated Neuroinflammation/ Neurodegeneration and Memory Impairment in Scopolamine-Induced Amnesia Mice Model

(2018) Tahir Muhammad et al.   Journal of Neuroimmune Pharmacology

Identification of Proteins Differentially Expressed in the Striatum by Melatonin in a Middle Cerebral Artery Occlusion Rat Model—a Proteomic and in silico Approach

(2018) Fawad Ali Shah et al.   Frontiers in Neuroscience

Neuroprotective Effect of Quercetin Against the Detrimental Effects of LPS in the Adult Mouse Brain

(2018) Amjad Khan et al.   Frontiers in Pharmacology

Antarctic Krill Oil Diet Protects against Lipopolysaccharide-Induced Oxidative Stress, Neuroinflammation and Cognitive Impairment

(2017) Ji Choi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Long-term exposition to a high fat diet favors the appearance of β-amyloid depositions in the brain of C57BL/6J mice. A potential model of sporadic Alzheimer’s disease

(2017) Oriol Busquets et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Deletion of mammalian sterile 20-like kinase 1 attenuates neuronal loss and improves locomotor function in a mouse model of spinal cord trauma

(2017) Pan-feng Wang et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

17β-Estradiol via SIRT1/Acetyl-p53/NF-kB Signaling Pathway Rescued Postnatal Rat Brain Against Acute Ethanol Intoxication

(2017) Mehtab Khan et al.   MOLECULAR NEUROBIOLOGY

Oxidative Stress in Neurodegenerative Diseases: From Molecular Mechanisms to Clinical Applications

(2017) Zewen Liu et al.   Oxidative Medicine and Cellular Longevity

Alzheimer's disease and metabolic syndrome: A link from oxidative stress and inflammation to neurodegeneration

(2017) Eduardo Rojas-Gutierrez et al.   SYNAPSE

Disulfiram/copper selectively eradicates AML leukemia stem cells in vitro and in vivo by simultaneous induction of ROS-JNK and inhibition of NF-κB and Nrf2

(2017) Bing Xu et al.   Cell Death & Disease

Type 2 Diabetes Mellitus, Dyslipidemia, and Alzheimer's Disease

(2017) Cynthia M. Carlsson   JOURNAL OF ALZHEIMERS DISEASE

Palmitic Acid-BSA enhances Amyloid-β production through GPR40-mediated dual pathways in neuronal cells: Involvement of the Akt/mTOR/HIF-1α and Akt/NF-κB pathways

(2017) Jeong Yeon Kim et al.   Scientific Reports

Regulation of Myocardial Cell Growth and Death by the Hippo Pathway

(2016) Shohei Ikeda et al.   CIRCULATION JOURNAL

Anthocyanins abrogate glutamate-induced AMPK activation, oxidative stress, neuroinflammation, and neurodegeneration in postnatal rat brain

(2016) Shahid Ali Shah et al.   Journal of Neuroinflammation

Insulin Resistance Prevents AMPK-induced Tau Dephosphorylation through Akt-mediated Increase in AMPKSer-485Phosphorylation

(2015) Bhumsoo Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Brain metabolic stress and neuroinflammation at the basis of cognitive impairment in Alzheimer’s disease

(2015) Fernanda G. De Felice et al.   Frontiers in Aging Neuroscience

Role of Non-Neuronal Cells in Body Weight and Appetite Control

(2015) Pilar Argente-Arizón et al.   Frontiers in Endocrinology

The role of reciprocal activation of cAbl and Mst1 in the Oxidative death of cultured astrocytes

(2014) Sook-Jeong Lee et al.   GLIA

MST1 is a key regulator of beta cell apoptosis and dysfunction in diabetes

(2014) Amin Ardestani et al.   NATURE MEDICINE

Mst1 inhibits autophagy by promoting the interaction between Beclin1 and Bcl-2

(2013) Yasuhiro Maejima et al.   NATURE MEDICINE

Oxidative Stress and the Pathogenesis of Alzheimer's Disease

(2013) Yan Zhao et al.   Oxidative Medicine and Cellular Longevity

The Classification of Microglial Activation Phenotypes on Neurodegeneration and Regeneration in Alzheimer’s Disease Brain

(2012) Megan M. Varnum et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Metabolic syndrome: definitions and controversies

(2011) Eva Kassi et al.   BMC Medicine

Hippo/Mst1 Stimulates Transcription of the Proapoptotic Mediator NOXA in a FoxO1-Dependent Manner

(2011) K. Valis et al.   CANCER RESEARCH

Daxx mediates activation-induced cell death in microglia by triggering MST1 signalling

(2011) Hee Jae Yun et al.   EMBO JOURNAL

The c-Abl-MST1 Signaling Pathway Mediates Oxidative Stress-Induced Neuronal Cell Death

(2011) L. Xiao et al.   JOURNAL OF NEUROSCIENCE

MST1 Promotes Apoptosis through Phosphorylation of Histone H2AX

(2010) Weihong Wen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proapoptotic Rassf1A/Mst1 signaling in cardiac fibroblasts is protective against pressure overload in mice

(2010) Dominic P. Del Re et al.   JOURNAL OF CLINICAL INVESTIGATION

Meta-Analysis of Alzheimer's Disease Risk with Obesity, Diabetes, and Related Disorders

(2009) Louis A. Profenno et al.   BIOLOGICAL PSYCHIATRY

c-Jun N-terminal Kinase Enhances MST1-mediated Pro-apoptotic Signaling through Phosphorylation at Serine 82

(2009) Wenzhi Bi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphoinositide 3-Kinase/Akt Inhibits MST1-Mediated Pro-apoptotic Signaling through Phosphorylation of Threonine 120

(2009) Zengqiang Yuan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanisms of Neurodegeneration and Regeneration in Alcoholism

(2008) F. T. Crews et al.   ALCOHOL AND ALCOHOLISM

Insulin Resistance and Alzheimers Disease: Molecular Links & Clinical Implications

(2008) Karen Neumann et al.   Current Alzheimer Research

Mechanism of alcohol-induced oxidative stress and neuronal injury

(2008) James Haorah et al.   FREE RADICAL BIOLOGY AND MEDICINE

JNK and ERK1/2 pathways have a dual opposite effect on the expression of BACE1

(2008) Elena Tamagno et al.   NEUROBIOLOGY OF AGING