MST1 is a key regulator of beta cell apoptosis and dysfunction in diabetes

Loss of Pdk1-Foxo1 Signaling in Myeloid Cells Predisposes to Adipose Tissue Inflammation and Insulin Resistance

(2012) Y. Kawano et al.   DIABETES

TCF7L2 promotes beta cell regeneration in human and mouse pancreas

(2012) L. Shu et al.   DIABETOLOGIA

Pdx1 Is Post-Translationally Modified In vivo and Serine 61 Is the Principal Site of Phosphorylation

(2012) Thomas Frogne et al.   PLoS One

Protein kinases of the Hippo pathway: Regulation and substrates

(2012) Joseph Avruch et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Mst1 regulates integrin-dependent thymocyte trafficking and antigen recognition in the thymus

(2012) Yoshihiro Ueda et al.   Nature Communications

Hippo/Mst1 Stimulates Transcription of the Proapoptotic Mediator NOXA in a FoxO1-Dependent Manner

(2011) K. Valis et al.   CANCER RESEARCH

Daxx mediates activation-induced cell death in microglia by triggering MST1 signalling

(2011) Hee Jae Yun et al.   EMBO JOURNAL

Neutralizing Interleukin-1β (IL-1β) Induces β-Cell Survival by Maintaining PDX1 Protein Nuclear Localization

(2011) Amin Ardestani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GLUT2 (SLC2A2) is not the principal glucose transporter in human pancreatic beta cells: Implications for understanding genetic association signals at this locus

(2011) Laura J. McCulloch et al.   MOLECULAR GENETICS AND METABOLISM

GABA exerts protective and regenerative effects on islet beta cells and reverses diabetes

(2011) N. Soltani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deletion of Irs2 causes reduced kidney size in mice: role for inhibition of GSK3β?

(2010) Rosemarie M Carew et al.   BMC DEVELOPMENTAL BIOLOGY

 -Cell Dysfunctional ERAD/Ubiquitin/Proteasome System in Type 2 Diabetes Mediated by Islet Amyloid Polypeptide-Induced UCH-L1 Deficiency

(2010) S. Costes et al.   DIABETES

Proapoptotic Rassf1A/Mst1 signaling in cardiac fibroblasts is protective against pressure overload in mice

(2010) Dominic P. Del Re et al.   JOURNAL OF CLINICAL INVESTIGATION

Pcif1 modulates Pdx1 protein stability and pancreatic β cell function and survival in mice

(2010) Kathryn C. Claiborn et al.   JOURNAL OF CLINICAL INVESTIGATION

Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression

(2010) H. Song et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The BH3-only protein Bim plays a critical role in leukemia cell death triggered by concomitant inhibition of the PI3K/Akt and MEK/ERK1/2 pathways

(2009) M. Rahmani et al.   BLOOD

Mst1 and Mst2 Maintain Hepatocyte Quiescence and Suppress Hepatocellular Carcinoma Development through Inactivation of the Yap1 Oncogene

(2009) Dawang Zhou et al.   CANCER CELL

CXCL10 Impairs β Cell Function and Viability in Diabetes through TLR4 Signaling

(2009) Fabienne T. Schulthess et al.   Cell Metabolism

Proinflammatory Cytokines Activate the Intrinsic Apoptotic Pathway in  -Cells

(2009) L. G. Grunnet et al.   DIABETES

Transfection of Rat Pancreatic Islet Tissue by Polymeric Gene Vectors

(2009) Han Chang Kang et al.   Diabetes Technology & Therapeutics

Glucose Regulates Steady-state Levels of PDX1 via the Reciprocal Actions of GSK3 and AKT Kinases

(2009) Rohan K. Humphrey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

c-Jun N-terminal Kinase Enhances MST1-mediated Pro-apoptotic Signaling through Phosphorylation at Serine 82

(2009) Wenzhi Bi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphoinositide 3-Kinase/Akt Inhibits MST1-Mediated Pro-apoptotic Signaling through Phosphorylation of Threonine 120

(2009) Zengqiang Yuan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Cell-Intrinsic Role for Mst1 in Regulating Thymocyte Egress

(2009) Y. Dong et al.   JOURNAL OF IMMUNOLOGY

Glucose Effects on Beta-Cell Growth and Survival Require Activation of Insulin Receptors and Insulin Receptor Substrate 2

(2009) A. Assmann et al.   MOLECULAR AND CELLULAR BIOLOGY

Mst1-FoxO Signaling Protects Naïve T Lymphocytes from Cellular Oxidative Stress in Mice

(2009) Juhyun Choi et al.   PLoS One

Biosignaling of mammalian Ste20-related kinases

(2008) Pin Ling et al.   CELLULAR SIGNALLING

The Antiinflammatory Cytokine Interleukin-1 Receptor Antagonist Protects from High-Fat Diet-Induced Hyperglycemia

(2008) Nadine S. Sauter et al.   ENDOCRINOLOGY

Apoptosis-associated mitochondrial outer membrane permeabilization assays

(2008) Damien Arnoult   METHODS

Linear Motif Atlas for Phosphorylation-Dependent Signaling

(2008) M. L. Miller et al.   Science Signaling