PI3K/AKT/JNK/p38 signalling pathway-mediated neural apoptosis in the prefrontal cortex of mice is involved in the antidepressant-like effect of pioglitazone

Reversion of BDNF, Akt and CREB in Hippocampus of Chronic Unpredictable Stress Induced Rats: Effects of Phytochemical,Bacopa Monnieri

(2017) Somoday Hazra et al.   Psychiatry Investigation

Salvianolic acid B ameliorates depressive-like behaviors in chronic mild stress-treated mice: involvement of the neuroinflammatory pathway

(2016) Jin-qiang Zhang et al.   ACTA PHARMACOLOGICA SINICA

Apigenin ameliorates chronic mild stress-induced depressive behavior by inhibiting interleukin-1β production and NLRP3 inflammasome activation in the rat brain

(2016) Ruipeng Li et al.   BEHAVIOURAL BRAIN RESEARCH

Metabolomic analysis reveals metabolic disturbances in the prefrontal cortex of the lipopolysaccharide-induced mouse model of depression

(2016) Yu Wu et al.   BEHAVIOURAL BRAIN RESEARCH

Trazodone treatment protects neuronal-like cells from inflammatory insult by inhibiting NF-κB, p38 and JNK

(2015) Simona Daniele et al.   CELLULAR SIGNALLING

Therapeutic Actions of the Thiazolidinediones in Alzheimer’s Disease

(2015) María José Pérez et al.   PPAR Research

Mig-2 attenuates cisplatin-induced apoptosis of human glioma cells in vitro through AKT/JNK and AKT/p38 signaling pathways

(2014) Yun-wei Ou et al.   ACTA PHARMACOLOGICA SINICA

Contribution of neural cell death to depressive phenotypes of streptozotocin-induced diabetic mice

(2014) C. Chen et al.   Disease Models & Mechanisms

Antidepressant-like effect of atorvastatin in the forced swimming test in mice: The role of PPAR-gamma receptor and nitric oxide pathway

(2014) Arash Shahsavarian et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Neuroprotective activities of catalpol against CaMKII-dependent apoptosis induced by LPS in PC12 cells

(2013) Wenna Chen et al.   BRITISH JOURNAL OF PHARMACOLOGY

PPAR-γ: Therapeutic Prospects in Parkinson's Disease

(2013) Anna R. Carta   CURRENT DRUG TARGETS

Intracerebroventricular administration of lipopolysaccharide induces indoleamine-2,3-dioxygenase-dependent depression-like behaviors

(2013) Marcus A Lawson et al.   Journal of Neuroinflammation

The neurobiology of depression

(2012) E. Palazidou   BRITISH MEDICAL BULLETIN

Pathological parainflammation and endoplasmic reticulum stress in depression: potential translational targets through the CNS insulin, klotho and PPAR-γ systems

(2012) P W Gold et al.   MOLECULAR PSYCHIATRY

Pioglitazone Adjunctive Therapy for Moderate-to-Severe Major Depressive Disorder: Randomized Double-Blind Placebo-Controlled Trial

(2012) Khatereh Sepanjnia et al.   NEUROPSYCHOPHARMACOLOGY

NMDA receptor involvement in antidepressant-like effect of pioglitazone in the forced swimming test in mice

(2012) Mohammad Salehi-Sadaghiani et al.   PSYCHOPHARMACOLOGY

A role for Akt and glycogen synthase kinase-3 as integrators of dopamine and serotonin neurotransmission in mental health

(2011) Jean-Martin Beaulieu   JOURNAL OF PSYCHIATRY & NEUROSCIENCE

Involvement of PI3K, GSK-3β and PPARγ in the antidepressant-like effect of folic acid in the forced swimming test in mice

(2011) Josiane Budni et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Cognition and Depression: Current Status and Future Directions

(2010) Ian H. Gotlib et al.   Annual Review of Clinical Psychology

Altered expression of genes involved in inflammation and apoptosis in frontal cortex in major depression

(2010) R C Shelton et al.   MOLECULAR PSYCHIATRY

Molecular Mechanism of JNK/Bim/Bax Apoptotic Pathway Induced by TNF-α in Differentiated PC12 Cells*

(2010) Lan ZHANG et al.   PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS

The glucocorticoid receptor: Pivot of depression and of antidepressant treatment?

(2010) Christoph Anacker et al.   PSYCHONEUROENDOCRINOLOGY

Depression and immunity: A role for T cells?

(2009) Andrew H. Miller   BRAIN BEHAVIOR AND IMMUNITY

Evidence for Involvement of ERK, PI3K, and RSK in Induction of Bcl-2 by Valproate

(2008) Thomas K. Creson et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Pioglitazone inhibition of lipopolysaccharide-induced nitric oxide synthase is associated with altered activity of p38 MAP kinase and PI3K/Akt

(2008) Bin Xing et al.   Journal of Neuroinflammation