Rhodium‐Catalyzed Copper‐Assisted Intermolecular Domino C−H Annulation of 1,3‐Diynes with Picolinamides: Access to Pentacyclic π‐Extended Systems

Computational Characterization of the Mechanism for the Oxidative Coupling of Benzoic Acid and Alkynes by Rhodium/Copper and Rhodium/Silver Systems

(2018) Ignacio Funes-Ardoiz et al.   CHEMISTRY-A EUROPEAN JOURNAL

Weak Directing Group Steered Formal Oxidative [2+2+2]-Cyclization for Selective Benzannulation of Indoles

(2018) Kiran R. Bettadapur et al.   JOURNAL OF ORGANIC CHEMISTRY

An Orchestrated Unsymmetrical Annulation Episode of C(sp2)–H Bonds with Alkynes and Quinones: Access to Spiro-isoquinolones

(2018) Kallol Mukherjee et al.   ORGANIC LETTERS

Rhodium(III)-Catalyzed Oxidative Annulation of 2,2′-Bipyridine N-Oxides with Alkynes via Dual C–H Bond Activation

(2018) Xin Xu et al.   ORGANIC LETTERS

Highly Regioselective Domino Benzannulation Reaction of Buta-1,3-diynes to Construct Irregular Nanographenes

(2018) Wenlong Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A New Class of N-Doped Ionic PAHs via Intramolecular [4+2]-Cycloaddition between Arylpyridines and Alkynes

(2018) Ravindra D Mule et al.   CHEMICAL COMMUNICATIONS

A comprehensive overview of directing groups applied in metal-catalysed C–H functionalisation chemistry

(2018) Carlo Sambiagio et al.   CHEMICAL SOCIETY REVIEWS

Sulfoximine-Assisted One-Pot Unsymmetrical Multiple Annulation of Arenes: A Combined Experimental and Computational Study

(2018) Koushik Ghosh et al.   JOURNAL OF ORGANIC CHEMISTRY

One-Pot Unsymmetrical {[4 + 2] and [4 + 2]} Double Annulations of o/o′-C–H Bonds of Arenes: Access to Unusual Pyranoisoquinolines

(2018) Majji Shankar et al.   ORGANIC LETTERS

C–H activation-annulation on the N-heterocyclic carbene platform

(2018) Champak Dutta et al.   RSC Advances

Palladium-Catalyzed Hydride Addition/C–H Bond Activation Cascade: Cycloisomerization of 1,6-Diynes

(2018) José F. Rodríguez et al.   ORGANIC LETTERS

Amides as Weak Coordinating Groups in Proximal C-H Bond Activation

(2017) Riki Das et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

A Mild Rhodium Catalyzed Direct Synthesis of Quinolones from Pyridones: Application in the Detection of Nitroaromatics

(2017) Aniruddha Biswas et al.   JOURNAL OF ORGANIC CHEMISTRY

N-Doped Cationic PAHs by Rh(III)-Catalyzed Double C–H Activation and Annulation of 2-Arylbenzimidazoles with Alkynes

(2017) José M. Villar et al.   ORGANIC LETTERS

Cascade C–H Annulation of Aldoximes with Alkynes Using O2 as the Sole Oxidant: One-Pot Access to Multisubstituted Protoberberine Skeletons

(2017) Junbin Tang et al.   ORGANIC LETTERS

Synthesis of Fluorescent Indazoles by Palladium-Catalyzed Benzannulation of Pyrazoles with Alkynes

(2017) Og Soon Kim et al.   ORGANIC LETTERS

Synthesis of Naphthoquinolizinones through Rh(III)-Catalyzed Double C(sp2)–H Bond Carbenoid Insertion and Annulation of 2-Aryl-3-cyanopyridines with α-Diazo Carbonyl Compounds

(2017) Beibei Zhang et al.   ORGANIC LETTERS

Cobalt Catalyzed, Regioselective C(sp2)–H Activation of Amides with 1,3-Diynes

(2017) Subban Kathiravan et al.   ORGANIC LETTERS

Transformable Sulfoximine Assisted One-Pot Double Annulation of Vinylic C–H Bonds with Unactivated Alkynes

(2017) Majji Shankar et al.   ORGANIC LETTERS

Synthesis of Benzoquinolizinium Salts by Rh(III)-Catalyzed Cascade Double N-Annulation Reactions of Allylamines, Diarylacetylenes, and HBF4

(2017) Ye Ri Han et al.   ORGANIC LETTERS

Synthesis of Polycyclic Amides via Tandem RhIII -Catalyzed C−H Activation and Annulation from Dioxazolones and Alkynes

(2017) Guo-Tai Zhang et al.   Asian Journal of Organic Chemistry

Palladium-Catalyzed Selective Aryl Ring C-H Activation ofN-Acyl-2-aminobiaryls: Efficient Access to Multiaryl-Substituted Naphthalenes

(2016) Pratheepkumar Annamalai et al.   ADVANCED SYNTHESIS & CATALYSIS

Metal-Catalyzed Annulations through Activation and Cleavage of C−H Bonds

(2016) Moisés Gulías et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cooperative Reductive Elimination: The Missing Piece in the Oxidative-Coupling Mechanistic Puzzle

(2016) Ignacio Funes-Ardoiz et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Simple and Versatile Amide Directing Group for C−H Functionalizations

(2016) Ru-Yi Zhu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mild metal-catalyzed C–H activation: examples and concepts

(2016) T. Gensch et al.   CHEMICAL SOCIETY REVIEWS

Synthesis of Conjugated Polycyclic Quinoliniums by Rhodium(III)-Catalyzed Multiple C–H Activation and Annulation of Arylpyridiniums with Alkynes

(2016) Qingmei Ge et al.   ORGANIC LETTERS

Ru-Catalyzed One-Pot Diannulation of Heteroaryls: Direct Access to π-Conjugated Polycyclic Amides

(2016) Majji Shankar et al.   ORGANIC LETTERS

Carbonyl-assisted reverse regioselective cascade annulation of 2-acetylenic ketones triggered by Ru-catalyzed C–H activation

(2016) Krishna Kumar Gollapelli et al.   Chemical Science

Synthesis of Cyclopentadienols by Rhodium-Catalyzed C–H Activation of 8-Formylquinolines and [2+2+1] Carbocyclization with Alkynes

(2016) Xingwei Li et al.   ACS Catalysis

Undirected, Homogeneous C–H Bond Functionalization: Challenges and Opportunities

(2016) John F. Hartwig et al.   ACS Central Science

Substrate Activation Strategies in Rhodium(III)-Catalyzed Selective Functionalization of Arenes

(2015) Guoyong Song et al.   ACCOUNTS OF CHEMICAL RESEARCH

Chiral Cyclopentadienyls: Enabling Ligands for Asymmetric Rh(III)-Catalyzed C–H Functionalizations

(2015) Baihua Ye et al.   ACCOUNTS OF CHEMICAL RESEARCH

Transition-Metal-Catalyzed C–N Bond Forming Reactions Using Organic Azides as the Nitrogen Source: A Journey for the Mild and Versatile C–H Amination

(2015) Kwangmin Shin et al.   ACCOUNTS OF CHEMICAL RESEARCH

A Palladium(II)-Catalyzed CH Activation Cascade Sequence for Polyheterocycle Formation

(2015) Stephen P. Cooper et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rh/Cu-catalyzed multiple C–H, C–C, and C–N bond cleavage: facile synthesis of pyrido[2,1-a]indoles from 1-(pyridin-2-yl)-1H-indoles and γ-substituted propargyl alcohols

(2015) Ting Li et al.   CHEMICAL COMMUNICATIONS

Experimental and DFT Studies Explain Solvent Control of C–H Activation and Product Selectivity in the Rh(III)-Catalyzed Formation of Neutral and Cationic Heterocycles

(2015) David L. Davies et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of indoles and polycyclic amides via ruthenium(ii)-catalyzed C–H activation and annulation

(2015) Hui Lin et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Rhodium(iii)-catalyzed cascade oxidative annulation reactions of aryl imidazolium salts with alkynes involving multiple C–H bond activation

(2015) Qingmei Ge et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis of Polyheteroaromatic Compounds via Rhodium-Catalyzed Multiple C–H Bond Activation and Oxidative Annulation

(2015) Shiyong Peng et al.   ORGANIC LETTERS

RhI/RhIII catalyst-controlled divergent aryl/heteroaryl C–H bond functionalization of picolinamides with alkynes

(2015) Ángel Manu Martínez et al.   Chemical Science

Rhodium(III)–N-Heterocyclic Carbene-Driven Cascade C–H Activation Catalysis

(2015) Debasish Ghorai et al.   ACS Catalysis

Rhodium(III)-Catalyzed Oxidative Olefination of Picolinamides: Convenient Synthesis of 3-Alkenylpicolinamides

(2014) Jun Zhou et al.   ADVANCED SYNTHESIS & CATALYSIS

The CH Activation/1,3-Diyne Strategy: Highly Selective Direct Synthesis of Diverse Bisheterocycles by RhIIICatalysis

(2014) Da-Gang Yu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

One-Pot Synthesis of Highly Substituted Polyheteroaromatic Compounds by Rhodium(III)-Catalyzed Multiple CH Activation and Annulation

(2014) Jayachandran Jayakumar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Direct Functionalization with Complete and Switchable Positional Control: Free Phenol as a Role Model

(2014) Da-Gang Yu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ruthenium-Catalyzed Cascade CH Functionalization of Phenylacetophenones

(2014) Vaibhav P. Mehta et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Aromatic Homologation by Non-Chelate-Assisted RhIII-Catalyzed CH Functionalization of Arenes with Alkynes

(2014) Manh V. Pham et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of Extended π-Systems through C-H Activation

(2014) Yasutomo Segawa et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ligand-Enabled Triple CH Activation Reactions: One-Pot Synthesis of Diverse 4-Aryl-2-quinolinones from Propionamides

(2014) Youqian Deng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium(III)/Copper(II)-Promotedtrans-Selective Heteroaryl Acyloxylation of Alkynes: Stereodefined Access totrans-Enol Esters

(2014) Manh V. Pham et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of alkylidene pyrrolo[3,4-b]pyridin-7-one derivatives via RhIII-catalyzed cascade oxidative alkenylation/annulation of picolinamides

(2014) Ángel Manu Martínez et al.   CHEMICAL COMMUNICATIONS

Synthesis of Indolo[2,1-a]isoquinolines via a Triazene-Directed C–H Annulation Cascade

(2014) Huan Sun et al.   JOURNAL OF ORGANIC CHEMISTRY

Rhodium-Catalyzed Oxidative Annulation of Hydrazines with Alkynes Using a Nitrobenzene Oxidant

(2014) Deng Yuan Li et al.   ORGANIC LETTERS

Efficient Synthesis of Isoquinolines via Rh(III)-Catalyzed Oxidative Annu­lation of Picolinamides with Alkynes

(2014) Bing-Feng Shi et al.   SYNLETT

Transition metal-catalyzed direct nucleophilic addition of C–H bonds to carbon–heteroatom double bonds

(2014) Xi-Sha Zhang et al.   Chemical Science

Carboxylate-Assisted Ruthenium-Catalyzed Alkyne Annulations by C–H/Het–H Bond Functionalizations

(2013) Lutz Ackermann   ACCOUNTS OF CHEMICAL RESEARCH

Palladium-Catalyzed Through-Space C(sp3)H and C(sp2)H Bond Activation by 1,4-Palladium Migration: Efficient Synthesis of [3,4]-Fused Oxindoles

(2013) Tiffany Piou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

ICl-Mediated Intramolecular Twofold Iodoarylation of Diynes and Diynyl Diethers and Amines: Synthesis of Bis(2H-hydronaphthalene and chromene) and 2H-Quinoline Bearing an Alkenyl Iodide Moiety

(2013) Juntae Mo et al.   JOURNAL OF ORGANIC CHEMISTRY

Rhodium-Catalyzed Decarboxylative and Dehydrogenative Coupling of Maleic Acids with Alkynes and Alkenes

(2013) Masaki Itoh et al.   JOURNAL OF ORGANIC CHEMISTRY

Pd-Catalyzed Cascade Crossover Annulation of o-Alkynylarylhalides and Diarylacetylenes Leading to Dibenzo[a,e]pentalenes

(2013) Jian Zhao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

C–H bond activation enables the rapid construction and late-stage diversification of functional molecules

(2013) Joanna Wencel-Delord et al.   Nature Chemistry

Controlling Site Selectivity in Palladium-Catalyzed C–H Bond Functionalization

(2012) Sharon R. Neufeldt et al.   ACCOUNTS OF CHEMICAL RESEARCH

Beyond Directing Groups: Transition-Metal-Catalyzed CH Activation of Simple Arenes

(2012) Nadine Kuhl et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

CH Bond Functionalization: Emerging Synthetic Tools for Natural Products and Pharmaceuticals

(2012) Junichiro Yamaguchi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Activation of a C(sp3)H Bond by a Transient σ-Alkylpalladium(II) Complex: Synthesis of Spirooxindoles Through a Palladium-Catalyzed Domino Carbopalladation/C(sp3)C(sp3) Bond-Forming Process

(2012) Tiffany Piou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

C–C, C–O and C–N bond formation via rhodium(iii)-catalyzed oxidative C–H activation

(2012) Guoyong Song et al.   CHEMICAL SOCIETY REVIEWS

Cu–Rh Redox Relay Catalysts for Synthesis of Azaheterocycles via C–H Functionalization

(2012) Shunsuke Chiba   CHEMISTRY LETTERS

CH Activation: A Complementary Tool in the Total Synthesis of Complex Natural Products

(2012) David Y.-K. Chen et al.   CHEMISTRY-A EUROPEAN JOURNAL

Rhodium-Catalyzed Cascade Oxidative Annulation Leading to Substituted Naphtho[1,8-bc]pyrans by Sequential Cleavage of C(sp2)–H/C(sp3)–H and C(sp2)–H/O–H Bonds

(2012) Xing Tan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Hybrid System of Metal/Brønsted Acid Relay Catalysis for the Intramolecular Double Hydroarylation and Cationic Cyclization of Diyne Diethers and Diamines

(2012) Juntae Mo et al.   ORGANIC LETTERS

Adding Aliphatic C-H Bond Oxidations to Synthesis

(2012) M. C. White   SCIENCE

Weak Coordination as a Powerful Means for Developing Broadly Useful C–H Functionalization Reactions

(2011) Keary M. Engle et al.   ACCOUNTS OF CHEMICAL RESEARCH

If CH Bonds Could Talk: Selective CH Bond Oxidation

(2011) Timothy Newhouse et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Dehydrogenative Cross-Coupling: Forming Carbon−Carbon Bonds by Oxidizing Two Carbon−Hydrogen Bonds

(2011) Charles S. Yeung et al.   CHEMICAL REVIEWS

Carboxylate-Assisted Transition-Metal-Catalyzed C−H Bond Functionalizations: Mechanism and Scope

(2011) Lutz Ackermann   CHEMICAL REVIEWS

Towards mild metal-catalyzed C–H bond activation

(2011) Joanna Wencel-Delord et al.   CHEMICAL SOCIETY REVIEWS

Recent developments in natural product synthesis using metal-catalysed C–H bond functionalisation

(2011) Lindsay McMurray et al.   CHEMICAL SOCIETY REVIEWS

Synthesis of Quinolines via Rh(III)-Catalyzed Oxidative Annulation of Pyridines

(2011) Guoyong Song et al.   JOURNAL OF ORGANIC CHEMISTRY

“Rollover” cyclometalation – early history, recent developments, mechanistic insights and application aspects

(2011) Burkhard Butschke et al.   Chemical Science

Polyheterocycles by Palladium(II)-Catalyzed Oxidative Domino Reactions Involving Direct CH Functionalization

(2010) Renrong Liu et al.   ADVANCED SYNTHESIS & CATALYSIS

Rhodium-catalyzed Oxidative Coupling/Cyclization of Benzamides with Alkynes via C–H Bond Cleavage

(2010) Satoshi Mochida et al.   CHEMISTRY LETTERS

Oxidative Coupling of Aromatic Substrates with Alkynes and Alkenes under Rhodium Catalysis

(2010) Tetsuya Satoh et al.   CHEMISTRY-A EUROPEAN JOURNAL

Rh-Catalyzed Oxidative Coupling between Primary and Secondary Benzamides and Alkynes: Synthesis of Polycyclic Amides

(2010) Guoyong Song et al.   JOURNAL OF ORGANIC CHEMISTRY

Construction of Nitrogen-Containing Heterocycles by CH Bond Functionalization

(2009) Praew Thansandote et al.   CHEMISTRY-A EUROPEAN JOURNAL

Fused Ring Construction around Pyrrole, Indole, and Related Compounds via Palladium-Catalyzed Oxidative Coupling with Alkynes

(2009) Mana Yamashita et al.   JOURNAL OF ORGANIC CHEMISTRY

Fluorescent Naphthyl- and Anthrylazoles from the Catalytic Coupling of Phenylazoles with Internal Alkynes through the Cleavage of Multiple CH Bonds

(2008) Nobuyoshi Umeda et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION