标题
Uraemic syndrome of chronic kidney disease: altered remote sensing and signalling
作者
关键词
-
出版物
Nature Reviews Nephrology
Volume -, Issue -, Pages -
出版商
Springer Nature
发表日期
2019-02-07
DOI
10.1038/s41581-019-0111-1
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- The SLC22 Transporter Family: A Paradigm for the Impact of Drug Transporters on Metabolic Pathways, Signaling, and Disease
- (2018) Sanjay K. Nigam Annual Review of Pharmacology and Toxicology
- The old and new biochemistry of polyamines
- (2018) Dong-Hun Bae et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Nitric oxide bioavailability dysfunction involves in atherosclerosis
- (2018) Jing-yi Chen et al. BIOMEDICINE & PHARMACOTHERAPY
- Kynurenic Acid and Gpr35 Regulate Adipose Tissue Energy Homeostasis and Inflammation
- (2018) Leandro Z. Agudelo et al. Cell Metabolism
- Proximal Tubular Secretory Clearance
- (2018) Ke Wang et al. Clinical Journal of the American Society of Nephrology
- Altered microbiome in chronic kidney disease: systemic effects of gut-derived uremic toxins
- (2018) Wei Ling Lau et al. CLINICAL SCIENCE
- Probiotic Lactobacillus paracasei HII01 protects rats against obese-insulin resistance-induced kidney injury and impaired renal organic anion transporter 3 (Oat3) function
- (2018) Keerati Wanchai et al. CLINICAL SCIENCE
- Metabolic Enzyme System and Transport Pathways in Chronic Kidney Diseases
- (2018) Bin Liu et al. CURRENT DRUG METABOLISM
- The systems biology of uric acid transporters
- (2018) Sanjay K. Nigam et al. CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION
- The scaffold protein PDZK1 modulates expression and function of the organic anion transporting polypeptide 2B1
- (2018) Celio Ferreira et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- The role of OAT2 (SLC22A7) in the cyclic nucleotide biokinetics of human erythrocytes
- (2018) Georg Sager et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Residual Function Effectively Controls Plasma Concentrations of Secreted Solutes in Patients on Twice Weekly Hemodialysis
- (2018) Sheldon C. Leong et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Post-translational modifications of transporters
- (2018) Lindsay C. Czuba et al. PHARMACOLOGY & THERAPEUTICS
- The aryl hydrocarbon receptor in the crossroad of signalling networks with therapeutic value
- (2018) Ángel C. Roman et al. PHARMACOLOGY & THERAPEUTICS
- Role of Bile Acids in Metabolic Control
- (2018) Antonio Molinaro et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- A novel SNP in the 5’ regulatory region of organic anion transporter 1 is associated with chronic kidney disease
- (2018) Chiao-Yin Sun et al. Scientific Reports
- Identification of ABCG2 as an Exporter of Uremic Toxin Indoxyl Sulfate in Mice and as a Crucial Factor Influencing CKD Progression
- (2018) T. Takada et al. Scientific Reports
- Uremic Toxin Clearance and Cardiovascular Toxicities
- (2018) Robert Mair et al. Toxins
- Indoxyl Sulfate Promotes Macrophage IL-1β Production by Activating Aryl Hydrocarbon Receptor/NF-κ/MAPK Cascades, but the NLRP3 inflammasome Was Not Activated
- (2018) Takuya Wakamatsu et al. Toxins
- Indoxyl Sulfate, a Uremic Toxin, Stimulates Reactive Oxygen Species Production and Erythrocyte Cell Death Supposedly by an Organic Anion Transporter 2 (OAT2) and NADPH Oxidase Activity-Dependent Pathways
- (2018) Gabriela Dias et al. Toxins
- Dietary Alteration of the Gut Microbiome and Its Impact on Weight and Fat Mass: A Systematic Review and Meta-Analysis
- (2018) George John et al. Genes
- Kynurenic Acid: The Janus-Faced Role of an Immunomodulatory Tryptophan Metabolite and Its Link to Pathological Conditions
- (2018) Elisa Wirthgen et al. Frontiers in Immunology
- Uric Acid Impairs Insulin Signaling by Promoting Enpp1 Binding to Insulin Receptor in Human Umbilical Vein Endothelial Cells
- (2018) Eliezer J. Tassone et al. Frontiers in Endocrinology
- CMPF, a Metabolite Formed Upon Prescription Omega-3-Acid Ethyl Ester Supplementation, Prevents and Reverses Steatosis
- (2018) Kacey J. Prentice et al. EBioMedicine
- Genetics of serum urate concentrations and gout in a high-risk population, patients with chronic kidney disease
- (2018) Jiaojiao Jing et al. Scientific Reports
- Effects of nonsteroidal anti-inflammatory drugs on the renal excretion of indoxyl sulfate, a nephro-cardiovascular toxin, in rats
- (2017) Chung-Ping Yu et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- The nature, consequences, and management of neurological disorders in chronic kidney disease
- (2017) Bahman Jabbari et al. Hemodialysis International
- The drug transporter OAT3 (SLC22A8) and endogenous metabolite communication via the gut–liver–kidney axis
- (2017) Kevin T. Bush et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Residual renal function: a paradigm shift
- (2017) Jerome Lowenstein et al. KIDNEY INTERNATIONAL
- Role of uremic toxin indoxyl sulfate in the progression of cardiovascular disease
- (2017) Huichang Gao et al. LIFE SCIENCES
- Kynurenine pathway metabolism and the microbiota-gut-brain axis
- (2017) P.J. Kennedy et al. NEUROPHARMACOLOGY
- L-Tryptophan-kynurenine pathway enzymes are therapeutic target for neuropsychiatric diseases: Focus on cell type differences
- (2017) Hidetsugu Fujigaki et al. NEUROPHARMACOLOGY
- The kynurenine pathway and the brain: Challenges, controversies and promises
- (2017) Robert Schwarcz et al. NEUROPHARMACOLOGY
- Aryl hydrocarbon receptor (AhR) and its endogenous agonist – indoxyl sulfate in chronic kidney disease
- (2017) Tomasz Kamiński et al. Postepy Higieny I Medycyny Doswiadczalnej
- Furan fatty acids – Beneficial or harmful to health?
- (2017) Long Xu et al. PROGRESS IN LIPID RESEARCH
- Residual Kidney Function: Implications in the Era of Personalized Medicine
- (2017) Tariq Shafi et al. SEMINARS IN DIALYSIS
- Several adaptor proteins promote intracellular localisation of the transporter MRP4/ABCC4 in platelets and haematopoietic cells
- (2017) Yvonne Schaletzki et al. THROMBOSIS AND HAEMOSTASIS
- Key Role for the Organic Anion Transporters, OAT1 and OAT3, in the in vivo Handling of Uremic Toxins and Solutes
- (2017) Wei Wu et al. Scientific Reports
- Microbiota-derived uremic retention solutes: perpetrators of altered nonrenal drug clearance in kidney disease
- (2017) Alexander J Prokopienko et al. Expert Review of Clinical Pharmacology
- Paricalcitol attenuates indoxyl sulfate-induced apoptosis through the inhibition of MAPK, Akt, and NF-kB activation in HK-2 cells
- (2017) Jung Sun Park et al. KOREAN JOURNAL OF INTERNAL MEDICINE
- Physiological functions and pathogenic potential of uric acid: A review
- (2017) Rashika El Ridi et al. Journal of Advanced Research
- Uremic Solutes in Chronic Kidney Disease and Their Role in Progression
- (2017) Jan A. J. G. van den Brand et al. PLoS One
- The Effects of CKD on Cytochrome P450–Mediated Drug Metabolism
- (2016) Matthew A. Ladda et al. ADVANCES IN CHRONIC KIDNEY DISEASE
- A Randomized, Controlled Trial of Oral Intestinal Sorbent AST-120 on Renal Function Deterioration in Patients with Advanced Renal Dysfunction
- (2016) R.-h. Cha et al. Clinical Journal of the American Society of Nephrology
- Synbiotics Easing Renal Failure by Improving Gut Microbiology (SYNERGY): A Randomized Trial
- (2016) M. Rossi et al. Clinical Journal of the American Society of Nephrology
- An Organic Anion Transporter 1 (OAT1)-centered Metabolic Network
- (2016) Henry C. Liu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Functions of Polyamines in Mammals
- (2016) Anthony E. Pegg JOURNAL OF BIOLOGICAL CHEMISTRY
- Identification and Characterization of Trimethylamine-N-oxide Uptake and Efflux Transporters
- (2016) Wendy A. Teft et al. MOLECULAR PHARMACEUTICS
- Effect of a sustained difference in hemodialytic clearance on the plasma levels of p-cresol sulfate and indoxyl sulfate
- (2016) Orlando Camacho et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- The gut–kidney axis
- (2016) Pieter Evenepoel et al. PEDIATRIC NEPHROLOGY
- Indoxyl sulfate promotes vascular smooth muscle cell calcification via the JNK/Pit-1 pathway
- (2016) Yiru Wu et al. RENAL FAILURE
- Indoxyl Sulfate—Review of Toxicity and Therapeutic Strategies
- (2016) Sheldon Leong et al. Toxins
- Organic Anion Transporting Polypeptides 1B1 and 1B3 Play an Important Role in Uremic Toxin Handling and Drug-Uremic Toxin Interactions in the Liver
- (2016) Toshihiro Sato et al. JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES
- A PDZ-Like Motif in the Biliary Transporter ABCB4 Interacts with the Scaffold Protein EBP50 and Regulates ABCB4 Cell Surface Expression
- (2016) Quitterie Venot et al. PLoS One
- The Influence of Prebiotic Arabinoxylan Oligosaccharides on Microbiota Derived Uremic Retention Solutes in Patients with Chronic Kidney Disease: A Randomized Controlled Trial
- (2016) Ruben Poesen et al. PLoS One
- Untargeted plasma and tissue metabolomics in rats with chronic kidney disease given AST-120
- (2016) Thomas J. Velenosi et al. Scientific Reports
- Hyperuricemia in acute gastroenteritis is caused by decreased urate excretion via ABCG2
- (2016) Hirotaka Matsuo et al. Scientific Reports
- Chemical communication in the gut: Effects of microbiota-generated metabolites on gastrointestinal bacterial pathogens
- (2015) Stefanie L. Vogt et al. ANAEROBE
- Handling of Drugs, Metabolites, and Uremic Toxins by Kidney Proximal Tubule Drug Transporters
- (2015) S. K. Nigam et al. Clinical Journal of the American Society of Nephrology
- Drug Transporters in the Central Nervous System
- (2015) Bruno Stieger et al. CLINICAL PHARMACOKINETICS
- A balanced view of the cerebrospinal fluid composition and functions: Focus on adult humans
- (2015) Reynold Spector et al. EXPERIMENTAL NEUROLOGY
- Gut microbiome in chronic kidney disease
- (2015) Maria R. Wing et al. EXPERIMENTAL PHYSIOLOGY
- Uric acid promotes chemokine and adhesion molecule production in vascular endothelium via nuclear factor-kappa B signaling
- (2015) W.Y. Liang et al. NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
- The Organic Anion Transporter (OAT) Family: A Systems Biology Perspective
- (2015) Sanjay K. Nigam et al. PHYSIOLOGICAL REVIEWS
- The Chronic Kidney Disease-Colonic Axis
- (2015) Madeleine V. Pahl et al. SEMINARS IN DIALYSIS
- Developmental Regulation of Drug-Processing Genes in Livers of Germ-Free Mice
- (2015) Felcy Pavithra Selwyn et al. TOXICOLOGICAL SCIENCES
- Indoxyl sulfate induces oxidative stress and hypertrophy in cardiomyocytes by inhibiting the AMPK/UCP2 signaling pathway
- (2015) Ke Yang et al. TOXICOLOGY LETTERS
- The Furan Fatty Acid Metabolite CMPF Is Elevated in Diabetes and Induces β Cell Dysfunction
- (2014) Kacey J. Prentice et al. Cell Metabolism
- Effect of Increasing Dietary Fiber on Plasma Levels of Colon-Derived Solutes in Hemodialysis Patients
- (2014) T. L. Sirich et al. Clinical Journal of the American Society of Nephrology
- Phase 0 and phase III transport in various organs: Combined concept of phases in xenobiotic transport and metabolism
- (2014) Barbara Döring et al. DRUG METABOLISM REVIEWS
- Dietary fiber effects in chronic kidney disease: a systematic review and meta-analysis of controlled feeding trials
- (2014) L Chiavaroli et al. EUROPEAN JOURNAL OF CLINICAL NUTRITION
- Transporters MCT8 and OATP1C1 maintain murine brain thyroid hormone homeostasis
- (2014) Steffen Mayerl et al. JOURNAL OF CLINICAL INVESTIGATION
- The Uremic Toxicity of Indoxyl Sulfate and p-Cresyl Sulfate: A Systematic Review
- (2014) R. Vanholder et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Randomized Placebo-Controlled EPPIC Trials of AST-120 in CKD
- (2014) G. Schulman et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- What do drug transporters really do?
- (2014) Sanjay K. Nigam NATURE REVIEWS DRUG DISCOVERY
- ABCG2 Dysfunction Increases Serum Uric Acid by Decreased Intestinal Urate Excretion
- (2014) Tappei Takada et al. NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
- Regulation of ABCC6 Trafficking and Stability by a Conserved C-terminal PDZ-Like Sequence
- (2014) Peng Xue et al. PLoS One
- The Kidney and Uremic Toxin Removal: Glomerulus or Tubule?
- (2014) Rosalinde Masereeuw et al. SEMINARS IN NEPHROLOGY
- Organic Cation Transporter OCTs (SLC22) and MATEs (SLC47) in the Human Kidney
- (2013) Hideyuki Motohashi et al. AAPS Journal
- Cell proliferation, potassium channels, polyamines and their interactions: a mini review
- (2013) Thomas M. Weiger et al. AMINO ACIDS
- p-Cresyl sulfate induces osteoblast dysfunction through activating JNK and p38 MAPK pathways
- (2013) Hisae Tanaka et al. BONE
- Microbiota Modulate Behavioral and Physiological Abnormalities Associated with Neurodevelopmental Disorders
- (2013) Elaine Y. Hsiao et al. CELL
- Metabolomics in chronic kidney disease
- (2013) Ying-Yong Zhao CLINICA CHIMICA ACTA
- Uric acid transporter ABCG2 is increased in the intestine of the 5/6 nephrectomy rat model of chronic kidney disease
- (2013) Hirofumi Yano et al. Clinical and Experimental Nephrology
- Aliphatic polyamines in physiology and diseases
- (2013) D. Ramani et al. CLINICAL NUTRITION
- The effects of acute renal failure on drug metabolism
- (2013) Barbara J Philips et al. Expert Opinion on Drug Metabolism & Toxicology
- Subcutaneous interstitial pressure and volume characteristics in renal impairment associated with edema
- (2013) Leonard M. Ebah et al. KIDNEY INTERNATIONAL
- Cationic uremic toxins affect human renal proximal tubule cell functioning through interaction with the organic cation transporter
- (2013) Carolien M. S. Schophuizen et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Indoxyl sulfate promotes vascular smooth muscle cell senescence with upregulation of p53, p21, and prelamin A through oxidative stress
- (2012) Gulinuer Muteliefu et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Renal Transporters in Drug Development
- (2012) Kari M. Morrissey et al. Annual Review of Pharmacology and Toxicology
- Current Understanding of Drug Disposition in Kidney Disease
- (2012) Judith Naud et al. JOURNAL OF CLINICAL PHARMACOLOGY
- Kynurenic acid: a metabolite with multiple actions and multiple targets in brain and periphery
- (2012) Flavio Moroni et al. JOURNAL OF NEURAL TRANSMISSION
- Indoxyl sulfate-induced epithelial-to-mesenchymal transition and apoptosis of renal tubular cells as novel mechanisms of progression of renal disease
- (2012) Su Hyun Kim et al. LABORATORY INVESTIGATION
- Kynurenines in the mammalian brain: when physiology meets pathology
- (2012) Robert Schwarcz et al. NATURE REVIEWS NEUROSCIENCE
- Organic anion transport pathways in antiviral handling in choroid plexus in Oat1 (Slc22a6) and Oat3 (Slc22a8) deficient tissue
- (2012) Megha A. Nagle et al. NEUROSCIENCE LETTERS
- Uremic Toxins Induce Kidney Fibrosis by Activating Intrarenal Renin–Angiotensin–Aldosterone System Associated Epithelial-to-Mesenchymal Transition
- (2012) Chiao-Yin Sun et al. PLoS One
- New Insights into Uric Acid Effects on the Progression and Prognosis of Chronic Kidney Disease
- (2012) Vassilis Filiopoulos et al. RENAL FAILURE
- An expanding range of targets for kynurenine metabolites of tryptophan
- (2012) Trevor W. Stone et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Indoxyl Sulfate Induces Epithelial-to-Mesenchymal Transition in Rat Kidneys and Human Proximal Tubular Cells
- (2011) Dilinaer Bolati et al. AMERICAN JOURNAL OF NEPHROLOGY
- Deletion of Multispecific Organic Anion Transporter Oat1/Slc22a6 Protects against Mercury-induced Kidney Injury
- (2011) Adriana M. Torres et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Linkage of Organic Anion Transporter-1 to Metabolic Pathways through Integrated “Omics”-driven Network and Functional Analysis
- (2011) Sun-Young Ahn et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The kynurenine system and immunoregulation
- (2011) Yvette Mándi et al. JOURNAL OF NEURAL TRANSMISSION
- Untargeted Metabolomics Identifies Enterobiome Metabolites and Putative Uremic Toxins as Substrates of Organic Anion Transporter 1 (Oat1)
- (2011) William R. Wikoff et al. JOURNAL OF PROTEOME RESEARCH
- Remote Communication through Solute Carriers and ATP Binding Cassette Drug Transporter Pathways: An Update on the Remote Sensing and Signaling Hypothesis
- (2011) W. Wu et al. MOLECULAR PHARMACOLOGY
- Functional Maturation of Drug Transporters in the Developing, Neonatal, and Postnatal Kidney
- (2011) D. E. Sweeney et al. MOLECULAR PHARMACOLOGY
- Uremic Encephalopathy and Other Brain Disorders Associated with Renal Failure
- (2011) Julian Seifter et al. SEMINARS IN NEUROLOGY
- Uremic Toxin Indoxyl Sulfate Inhibits Human Vascular Smooth Muscle Cell Proliferation
- (2011) Anaïs Mozar et al. THERAPEUTIC APHERESIS AND DIALYSIS
- Colonization-Induced Host-Gut Microbial Metabolic Interaction
- (2011) S. P. Claus et al. mBio
- Analysis of Three-dimensional Systems for Developing and Mature Kidneys Clarifies the Role of OAT1 and OAT3 in Antiviral Handling
- (2010) Megha A. Nagle et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Metabolite Profiling Identifies Markers of Uremia
- (2010) E. P. Rhee et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Regulation of Human Organic Anion Transporter 4 by Protein Kinase C and NHERF-1: Altering the Endocytosis of the Transporter
- (2010) Qiang Zhang et al. PHARMACEUTICAL RESEARCH
- Kynurenic Acid Is a Potent Endogenous Aryl Hydrocarbon Receptor Ligand that Synergistically Induces Interleukin-6 in the Presence of Inflammatory Signaling
- (2010) Brett C. DiNatale et al. TOXICOLOGICAL SCIENCES
- ROS and PDFG-β receptors are critically involved in indoxyl sulfate actions that promote vascular smooth muscle cell proliferation and migration
- (2009) Hidehisa Shimizu et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Functional significance of eIF5A and its hypusine modification in eukaryotes
- (2009) M. H. Park et al. AMINO ACIDS
- The Uremic Toxin 3-Indoxyl Sulfate Is a Potent Endogenous Agonist for the Human Aryl Hydrocarbon Receptor
- (2009) Jennifer C. Schroeder et al. BIOCHEMISTRY
- Impact of Gut Microbiota on Intestinal and Hepatic Levels of Phase 2 Xenobiotic-Metabolizing Enzymes in the Rat
- (2009) W. Meinl et al. DRUG METABOLISM AND DISPOSITION
- Interaction of Organic Cations with Organic Anion Transporters
- (2009) Sun-Young Ahn et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- SLCO4C1 Transporter Eliminates Uremic Toxins and Attenuates Hypertension and Renal Inflammation
- (2009) T. Toyohara et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Toward a Systems Level Understanding of Organic Anion and Other Multispecific Drug Transporters: A Remote Sensing and Signaling Hypothesis
- (2009) S.-Y. Ahn et al. MOLECULAR PHARMACOLOGY
- Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites
- (2009) W. R. Wikoff et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism
- (2009) T. A. Clayton et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Role of EUTox in Uremic Toxin Research
- (2009) Raymond Vanholder et al. SEMINARS IN DIALYSIS
- Asymmetric Dimethylarginine and Symmetric Dimethylarginine: Axis of Evil or Useful Alliance?
- (2009) Jan T. Kielstein et al. SEMINARS IN DIALYSIS
- The pregnane X receptor: from bench to bedside
- (2008) Xiaochao Ma et al. Expert Opinion on Drug Metabolism & Toxicology
- Multi-level Analysis of Organic Anion Transporters 1, 3, and 6 Reveals Major Differences in Structural Determinants of Antiviral Discrimination
- (2008) David M. Truong et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Effect of Hemodialysis on Hepatic Cytochrome P450 Functional Expression
- (2008) Josée Michaud et al. JOURNAL OF PHARMACOLOGICAL SCIENCES
- Urate Transport Across the Apical Membrane of Renal Proximal Tubules
- (2008) Hitoshi Endou et al. NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
- Multiple organic anion transporters contribute to net renal excretion of uric acid
- (2008) Satish A. Eraly et al. PHYSIOLOGICAL GENOMICS
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started