The drug transporter OAT3 (SLC22A8) and endogenous metabolite communication via the gut–liver–kidney axis
出版年份 2017 全文链接
标题
The drug transporter OAT3 (SLC22A8) and endogenous metabolite communication via the gut–liver–kidney axis
作者
关键词
-
出版物
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 292, Issue 38, Pages 15789-15803
出版商
American Society for Biochemistry & Molecular Biology (ASBMB)
发表日期
2017-08-02
DOI
10.1074/jbc.m117.796516
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- (2017) Emmanuelle Martinot et al. MOLECULAR ASPECTS OF MEDICINE
- The emerging pharmacology and function of GPR35 in the nervous system
- (2017) Amanda E. Mackenzie et al. NEUROPHARMACOLOGY
- Key Role for the Organic Anion Transporters, OAT1 and OAT3, in the in vivo Handling of Uremic Toxins and Solutes
- (2017) Wei Wu et al. Scientific Reports
- An Organic Anion Transporter 1 (OAT1)-centered Metabolic Network
- (2016) Henry C. Liu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The role of glucuronidation in drug resistance
- (2016) Zofia Mazerska et al. PHARMACOLOGY & THERAPEUTICS
- TGR5, Not Only a Metabolic Regulator
- (2016) Cong Guo et al. Frontiers in Physiology
- Handling of Drugs, Metabolites, and Uremic Toxins by Kidney Proximal Tubule Drug Transporters
- (2015) S. K. Nigam et al. Clinical Journal of the American Society of Nephrology
- Effects of sodium benzoate, a widely used food preservative, on glucose homeostasis and metabolic profiles in humans
- (2015) Belinda S. Lennerz et al. MOLECULAR GENETICS AND METABOLISM
- Peripheral Serotonin: a New Player in Systemic Energy Homeostasis
- (2015) MOLECULES AND CELLS
- MetaboAnalyst 3.0—making metabolomics more meaningful
- (2015) Jianguo Xia et al. NUCLEIC ACIDS RESEARCH
- The Organic Anion Transporter (OAT) Family: A Systems Biology Perspective
- (2015) Sanjay K. Nigam et al. PHYSIOLOGICAL REVIEWS
- Evolutionary Analysis and Classification of OATs, OCTs, OCTNs, and Other SLC22 Transporters: Structure-Function Implications and Analysis of Sequence Motifs
- (2015) Christopher Zhu et al. PLoS One
- The Furan Fatty Acid Metabolite CMPF Is Elevated in Diabetes and Induces β Cell Dysfunction
- (2014) Kacey J. Prentice et al. Cell Metabolism
- Bile acids and the gut microbiome
- (2014) Jason M. Ridlon et al. CURRENT OPINION IN GASTROENTEROLOGY
- A new perspective on the importance of glycine conjugation in the metabolism of aromatic acids
- (2014) Christoffel Petrus Stephanus Badenhorst et al. DRUG METABOLISM REVIEWS
- Diet, Metabolites, and “Western-Lifestyle” Inflammatory Diseases
- (2014) Alison N. Thorburn et al. IMMUNITY
- Mechanism underlying an elevated serum bile acid level in chronic renal failure patients
- (2014) Lei Chu et al. INTERNATIONAL UROLOGY AND NEPHROLOGY
- Pharmacokinetics of Equol, a Soy Isoflavone Metabolite, Changes with the Form of Equol (Dietary versus Intestinal Production) in Ovariectomized Rats
- (2014) LeeCole L. Legette et al. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
- What do drug transporters really do?
- (2014) Sanjay K. Nigam NATURE REVIEWS DRUG DISCOVERY
- Phenylalanine hydroxylase: Function, structure, and regulation
- (2013) Marte I. Flydal et al. IUBMB LIFE
- Metabolomics Reveals Signature of Mitochondrial Dysfunction in Diabetic Kidney Disease
- (2013) K. Sharma et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Organic anion transport pathways in antiviral handling in choroid plexus in Oat1 (Slc22a6) and Oat3 (Slc22a8) deficient tissue
- (2012) Megha A. Nagle et al. NEUROSCIENCE LETTERS
- Organic Anion and Cation SLC22 “Drug” Transporter (Oat1, Oat3, and Oct1) Regulation during Development and Maturation of the Kidney Proximal Tubule
- (2012) Thomas F. Gallegos et al. PLoS One
- Multiple tyrosine metabolites are GPR35 agonists
- (2012) Huayun Deng et al. Scientific Reports
- Deletion of Multispecific Organic Anion Transporter Oat1/Slc22a6 Protects against Mercury-induced Kidney Injury
- (2011) Adriana M. Torres et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Linkage of Organic Anion Transporter-1 to Metabolic Pathways through Integrated “Omics”-driven Network and Functional Analysis
- (2011) Sun-Young Ahn et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Untargeted Metabolomics Identifies Enterobiome Metabolites and Putative Uremic Toxins as Substrates of Organic Anion Transporter 1 (Oat1)
- (2011) William R. Wikoff et al. JOURNAL OF PROTEOME RESEARCH
- Remote Communication through Solute Carriers and ATP Binding Cassette Drug Transporter Pathways: An Update on the Remote Sensing and Signaling Hypothesis
- (2011) W. Wu et al. MOLECULAR PHARMACOLOGY
- Functional Maturation of Drug Transporters in the Developing, Neonatal, and Postnatal Kidney
- (2011) D. E. Sweeney et al. MOLECULAR PHARMACOLOGY
- Analysis of Three-dimensional Systems for Developing and Mature Kidneys Clarifies the Role of OAT1 and OAT3 in Antiviral Handling
- (2010) Megha A. Nagle et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Integrated, Nontargeted Ultrahigh Performance Liquid Chromatography/Electrospray Ionization Tandem Mass Spectrometry Platform for the Identification and Relative Quantification of the Small-Molecule Complement of Biological Systems
- (2009) Anne M. Evans et al. ANALYTICAL CHEMISTRY
- Organic anion transporters: discovery, pharmacology, regulation and roles in pathophysiology
- (2009) Adam L. VanWert et al. BIOPHARMACEUTICS & DRUG DISPOSITION
- Interaction of Organic Cations with Organic Anion Transporters
- (2009) Sun-Young Ahn et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Toward a Systems Level Understanding of Organic Anion and Other Multispecific Drug Transporters: A Remote Sensing and Signaling Hypothesis
- (2009) S.-Y. Ahn et al. MOLECULAR PHARMACOLOGY
- Understanding the role of tryptophan and serotonin metabolism in gastrointestinal function
- (2009) d. keszthelyi et al. NEUROGASTROENTEROLOGY AND MOTILITY
- Pathophysiological regulation of renal SLC22A organic ion transporters in acute kidney injury: Pharmacological and toxicological implications
- (2009) Hideyuki Saito PHARMACOLOGY & THERAPEUTICS
- Analysis of a large cluster of SLC22 transporter genes, including novel USTs, reveals species-specific amplification of subsets of family members
- (2009) Wei Wu et al. PHYSIOLOGICAL GENOMICS
- Untargeted Metabolomic Profiling as an Evaluative Tool of Fenofibrate-Induced Toxicology in Fischer 344 Male Rats
- (2009) Tetsuya Ohta et al. TOXICOLOGIC PATHOLOGY
- Multi-level Analysis of Organic Anion Transporters 1, 3, and 6 Reveals Major Differences in Structural Determinants of Antiviral Discrimination
- (2008) David M. Truong et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Organic Anion Transporter 3 Contributes to the Regulation of Blood Pressure
- (2008) V. Vallon et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Organic Anion Transporter 3 (Oat3/Slc22a8) Interacts with Carboxyfluoroquinolones, and Deletion Increases Systemic Exposure to Ciprofloxacin
- (2008) A. L. VanWert et al. MOLECULAR PHARMACOLOGY
- Targeting bile-acid signalling for metabolic diseases
- (2008) Charles Thomas et al. NATURE REVIEWS DRUG DISCOVERY
- Multiple organic anion transporters contribute to net renal excretion of uric acid
- (2008) Satish A. Eraly et al. PHYSIOLOGICAL GENOMICS
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