Pleiotropic Pharmacological Actions of Capsazepine, a Synthetic Analogue of Capsaicin, against Various Cancers and Inflammatory Diseases
出版年份 2019 全文链接
标题
Pleiotropic Pharmacological Actions of Capsazepine, a Synthetic Analogue of Capsaicin, against Various Cancers and Inflammatory Diseases
作者
关键词
-
出版物
MOLECULES
Volume 24, Issue 5, Pages 995
出版商
MDPI AG
发表日期
2019-03-13
DOI
10.3390/molecules24050995
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Formononetin-induced oxidative stress abrogates the activation of STAT3/5 signaling axis and suppresses the tumor growth in multiple myeloma preclinical model
- (2018) Chulwon Kim et al. CANCER LETTERS
- Targeting activator protein 1 signaling pathway by bioactive natural agents: Possible therapeutic strategy for cancer prevention and intervention
- (2018) Devesh Tewari et al. PHARMACOLOGICAL RESEARCH
- Pro-Apoptotic and Anti-Cancer Properties of Diosgenin: A Comprehensive and Critical Review
- (2018) Gautam Sethi et al. Nutrients
- Anti-myeloma Effects of Icariin Are Mediated Through the Attenuation of JAK/STAT3-Dependent Signaling Cascade
- (2018) Young Yun Jung et al. Frontiers in Pharmacology
- Celastrol Attenuates the Invasion and Migration and Augments the Anticancer Effects of Bortezomib in a Xenograft Mouse Model of Multiple Myeloma
- (2018) Muthu K. Shanmugam et al. Frontiers in Pharmacology
- Oleuropein induces apoptosis via abrogating NF-κB activation cascade in estrogen receptor-negative breast cancer cells
- (2018) Lian Liu et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- The Role of Signal Transducer and Activator of Transcription 3 (STAT3) and Its Targeted Inhibition in Hematological Malignancies
- (2018) Loukik Arora et al. Cancers
- Molecular Targets Modulated by Fangchinoline in Tumor Cells and Preclinical Models
- (2018) Myriam Mérarchi et al. MOLECULES
- Potential Anti-Inflammatory and Anti-Cancer Properties of Farnesol
- (2018) Young Jung et al. MOLECULES
- Ophiopogonin D, a Steroidal Glycoside Abrogates STAT3 Signaling Cascade and Exhibits Anti-Cancer Activity by Causing GSH/GSSG Imbalance in Lung Carcinoma
- (2018) Jong Lee et al. Cancers
- Do STAT3 inhibitors have potential in the future for cancer therapy?
- (2017) Andrea L.A. Wong et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- The Role of Resveratrol in Cancer Therapy
- (2017) Jeong-Hyeon Ko et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- The Roles of ROS in Cancer Heterogeneity and Therapy
- (2017) Paulo Luiz de Sá Junior et al. Oxidative Medicine and Cellular Longevity
- A novel benzimidazole derivative, MBIC inhibits tumor growth and promotes apoptosis via activation of ROS-dependent JNK signaling pathway in hepatocellular carcinoma
- (2017) Xiaoyun Dai et al. Oncotarget
- Identification of capsazepine as a novel inhibitor of system xc− and cancer-induced bone pain
- (2017) Jennifer Fazzari et al. Journal of Pain Research
- Nimbolide-Induced Oxidative Stress Abrogates STAT3 Signaling Cascade and Inhibits Tumor Growth in Transgenic Adenocarcinoma of Mouse Prostate Model
- (2016) Jingwen Zhang et al. ANTIOXIDANTS & REDOX SIGNALING
- Targeting transcription factor STAT3 for cancer prevention and therapy
- (2016) Edna Zhi Pei Chai et al. PHARMACOLOGY & THERAPEUTICS
- Bioactive natural products in cancer prevention and therapy: Progress and promise
- (2016) Anupam Bishayee et al. SEMINARS IN CANCER BIOLOGY
- Cancer prevention and therapy through the modulation of transcription factors by bioactive natural compounds
- (2016) Muthu K Shanmugam et al. SEMINARS IN CANCER BIOLOGY
- Targeting arachidonic acid pathway by natural products for cancer prevention and therapy
- (2016) Nagendra Sastry Yarla et al. SEMINARS IN CANCER BIOLOGY
- Capsazepine inhibits JAK/STAT3 signaling, tumor growth, and cell survival in prostate cancer
- (2016) Jong Hyun Lee et al. Oncotarget
- Systemic desensitization through TRPA1 channels by capsazepine and mustard oil - a novel strategy against inflammation and pain
- (2016) Katrin Kistner et al. Scientific Reports
- NF-κB in cancer therapy
- (2015) Feng Li et al. ARCHIVES OF TOXICOLOGY
- Analysis of the intricate relationship between chronic inflammation and cancer
- (2015) Edna Zhi Pei Chai et al. BIOCHEMICAL JOURNAL
- Isorhamnetin augments the anti-tumor effect of capeciatbine through the negative regulation of NF-κB signaling cascade in gastric cancer
- (2015) Kanjoormana A. Manu et al. CANCER LETTERS
- Targeting TNF-related apoptosis-inducing ligand (TRAIL) receptor by natural products as a potential therapeutic approach for cancer therapy
- (2015) Xiaoyun Dai et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- Involvement of apoptosis and calcium accumulation through TRPV1 channels in neurobiology of epilepsy
- (2015) M. Nazıroğlu et al. NEUROSCIENCE
- Garcinol sensitizes human head and neck carcinoma to cisplatin in a xenograft mouse model despite downregulation of proliferative biomarkers
- (2015) Feng Li et al. Oncotarget
- Natural Bioactives in Cancer Treatment and Prevention
- (2015) Yih-Shou Hsieh et al. Biomed Research International
- 6-Shogaol exerts anti-proliferative and pro-apoptotic effects through the modulation of STAT3 and MAPKs signaling pathways
- (2015) Sung-Moo Kim et al. MOLECULAR CARCINOGENESIS
- Targeting the STAT3 signaling pathway in cancer: Role of synthetic and natural inhibitors
- (2014) Kodappully Sivaraman Siveen et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Bioavailability of capsaicin and its implications for drug delivery
- (2014) William D. Rollyson et al. JOURNAL OF CONTROLLED RELEASE
- Epilepsy But Not Mobile Phone Frequency (900 MHz) Induces Apoptosis and Calcium Entry in Hippocampus of Epileptic Rat: Involvement of TRPV1 Channels
- (2014) Mustafa Nazıroğlu et al. JOURNAL OF MEMBRANE BIOLOGY
- TRPV1 Antagonism by Capsazepine Modulates Innate Immune Response in Mice Infected withPlasmodium bergheiANKA
- (2014) Elizabeth S. Fernandes et al. MEDIATORS OF INFLAMMATION
- Electromagnetic radiation (Wi-Fi) and epilepsy induce calcium entry and apoptosis through activation of TRPV1 channel in hippocampus and dorsal root ganglion of rats
- (2014) Vahid Ghazizadeh et al. METABOLIC BRAIN DISEASE
- Involvement of central TRPV1 receptors in pentylenetetrazole and amygdala-induced kindling in male rats
- (2014) Mohsen Shirazi et al. NEUROLOGICAL SCIENCES
- Vanilloids induce oral cancer apoptosis independent of TRPV1
- (2014) Cara B. Gonzales et al. ORAL ONCOLOGY
- Targeting death receptors for TRAIL by agents designed by Mother Nature
- (2014) Sahdeo Prasad et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Novel Medicines and Strategies in Cancer Treatment and Prevention
- (2014) Chih-Hsin Tang et al. Biomed Research International
- An anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL induced apoptosis through the induction of death receptors and downregulation of cell survival proteins
- (2013) Aruljothi Subramaniam et al. APOPTOSIS
- Emodin inhibits growth and induces apoptosis in an orthotopic hepatocellular carcinoma model by blocking activation of STAT3
- (2013) Aruljothi Subramaniam et al. BRITISH JOURNAL OF PHARMACOLOGY
- Piperine exerts anti-seizure effects via the TRPV1 receptor in mice
- (2013) Chang-Yuan Chen et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Natural Bioactives and Phytochemicals Serve in Cancer Treatment and Prevention
- (2013) Shun-Fa Yang et al. Evidence-based Complementary and Alternative Medicine
- Capsazepine concentration dependently inhibits currents in HEK 293 cells mediated by human hyperpolarization-activated cyclic nucleotide-gated 2 and 4 channels
- (2013) Guang-Feng Zuo et al. EXPERIMENTAL BIOLOGY AND MEDICINE
- TRPV1 antagonist capsazepine suppresses 4-AP-induced epileptiform activity in vitro and electrographic seizures in vivo
- (2013) Luis E. Gonzalez-Reyes et al. EXPERIMENTAL NEUROLOGY
- Malaria
- (2013) Nicholas J White et al. LANCET
- Thymoquinone Inhibits Tumor Growth and Induces Apoptosis in a Breast Cancer Xenograft Mouse Model: The Role of p38 MAPK and ROS
- (2013) Chern Chiuh Woo et al. PLoS One
- Potential role of signal transducer and activator of transcription (STAT)3 signaling pathway in inflammation, survival, proliferation and invasion of hepatocellular carcinoma
- (2012) Aruljothi Subramaniam et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Targeted inhibition of tumor proliferation, survival, and metastasis by pentacyclic triterpenoids: Potential role in prevention and therapy of cancer
- (2012) Muthu K. Shanmugam et al. CANCER LETTERS
- First Evidence That -Tocotrienol Inhibits the Growth of Human Gastric Cancer and Chemosensitizes It to Capecitabine in a Xenograft Mouse Model through the Modulation of NF- B Pathway
- (2012) K. A. Manu et al. CLINICAL CANCER RESEARCH
- A possible participation of transient receptor potential vanilloid type 1 channels in the antidepressant effect of fluoxetine
- (2012) Shyamshree S.S. Manna et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Capsazepine, a TRPV1 antagonist, sensitizes colorectal cancer cells to apoptosis by TRAIL through ROS–JNK–CHOP-mediated upregulation of death receptors
- (2012) Bokyung Sung et al. FREE RADICAL BIOLOGY AND MEDICINE
- Capillarisin inhibits iNOS, COX-2 expression, and proinflammatory cytokines in LPS-induced RAW 264.7 macrophages via the suppression of ERK, JNK, and NF-κB activation
- (2012) Suckbae Han et al. IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY
- Upsides and Downsides of Reactive Oxygen Species for Cancer: The Roles of Reactive Oxygen Species in Tumorigenesis, Prevention, and Therapy
- (2011) Subash C. Gupta et al. ANTIOXIDANTS & REDOX SIGNALING
- Multifaceted link between cancer and inflammation
- (2011) Gautam Sethi et al. BIOSCIENCE REPORTS
- β-Caryophyllene oxide inhibits growth and induces apoptosis through the suppression of PI3K/AKT/mTOR/S6K1 pathways and ROS-mediated MAPKs activation
- (2011) Kyung-Ran Park et al. CANCER LETTERS
- Targeting Cell Signaling and Apoptotic Pathways by Dietary Agents: Role in the Prevention and Treatment of Cancer
- (2011) Muthu Shanmugam et al. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
- Leukotriene B4 Mediates Inflammation via TRPV1 in Duct Obstruction-Induced Pancreatitis in Rats
- (2011) Steven R. Vigna et al. PANCREAS
- Hydrogen Sulfide and Neurogenic Inflammation in Polymicrobial Sepsis: Involvement of Substance P and ERK-NF-κB Signaling
- (2011) Seah-Fang Ang et al. PLoS One
- Effects of capsazepine, a transient receptor potential vanilloid type 1 antagonist, on morphine-induced antinociception, tolerance, and dependence in mice
- (2010) T.-L. Nguyen et al. BRITISH JOURNAL OF ANAESTHESIA
- Hydrogen sulfide promotes transient receptor potential vanilloid 1-mediated neurogenic inflammation in polymicrobial sepsis*
- (2010) Seah-Fang Ang et al. CRITICAL CARE MEDICINE
- Attenuation of anxiety-related behaviour after the antagonism of transient receptor potential vanilloid type 1 channels in the rat ventral hippocampus
- (2009) Carolina J.P.A. Santos et al. BEHAVIOURAL PHARMACOLOGY
- Potential pharmacological control of the NF-κB pathway
- (2009) Gautam Sethi et al. TRENDS IN PHARMACOLOGICAL SCIENCES
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now