Ophiopogonin D, a Steroidal Glycoside Abrogates STAT3 Signaling Cascade and Exhibits Anti-Cancer Activity by Causing GSH/GSSG Imbalance in Lung Carcinoma
出版年份 2018 全文链接
标题
Ophiopogonin D, a Steroidal Glycoside Abrogates STAT3 Signaling Cascade and Exhibits Anti-Cancer Activity by Causing GSH/GSSG Imbalance in Lung Carcinoma
作者
关键词
-
出版物
Cancers
Volume 10, Issue 11, Pages 427
出版商
MDPI AG
发表日期
2018-11-09
DOI
10.3390/cancers10110427
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- (2018) Chulwon Kim et al. CANCER LETTERS
- xCT (SLC7A11)-mediated metabolic reprogramming promotes non-small cell lung cancer progression
- (2018) Xiangming Ji et al. ONCOGENE
- Ophiopogonin D modulates multiple oncogenic signaling pathways, leading to suppression of proliferation and chemosensitization of human lung cancer cells
- (2018) Jong Hyun Lee et al. PHYTOMEDICINE
- Anti-myeloma Effects of Icariin Are Mediated Through the Attenuation of JAK/STAT3-Dependent Signaling Cascade
- (2018) Young Yun Jung et al. Frontiers in Pharmacology
- The Role of Signal Transducer and Activator of Transcription 3 (STAT3) and Its Targeted Inhibition in Hematological Malignancies
- (2018) Loukik Arora et al. Cancers
- Do STAT3 inhibitors have potential in the future for cancer therapy?
- (2017) Andrea L.A. Wong et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway
- (2017) Vasanthi S. Viswanathan et al. NATURE
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- (2016) Jingwen Zhang et al. ANTIOXIDANTS & REDOX SIGNALING
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- (2016) Muthu K Shanmugam et al. SEMINARS IN CANCER BIOLOGY
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- (2015) Jong Hyun Lee et al. CANCER LETTERS
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- (2015) Xiaoyun Dai et al. Molecular Oncology
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- (2015) Jong Hyun Lee et al. Oncotarget
- Ophiopogonin-D suppresses MDA-MB-435 cell adhesion and invasion by inhibiting matrix metalloproteinase-9
- (2015) YUANYUAN ZHANG et al. Molecular Medicine Reports
- Targeting the STAT3 signaling pathway in cancer: Role of synthetic and natural inhibitors
- (2014) Kodappully Sivaraman Siveen et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
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- (2014) Sung-Moo Kim et al. CANCER LETTERS
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- (2014) Gautam Sethi et al. Molecular Cancer
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- (2014) Muthu K. Shanmugam et al. MOLECULAR CARCINOGENESIS
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- (2013) Aruljothi Subramaniam et al. BRITISH JOURNAL OF PHARMACOLOGY
- Capillarisin inhibits constitutive and inducible STAT3 activation through induction of SHP-1 and SHP-2 tyrosine phosphatases
- (2013) Jong Hyun Lee et al. CANCER LETTERS
- Garcinol, a Polyisoprenylated Benzophenone Modulates Multiple Proinflammatory Signaling Cascades Leading to the Suppression of Growth and Survival of Head and Neck Carcinoma
- (2013) F. Li et al. Cancer Prevention Research
- β-caryophyllene oxide inhibits constitutive and inducible STAT3 signaling pathway through induction of the SHP-1 protein tyrosine phosphatase
- (2013) Chulwon Kim et al. MOLECULAR CARCINOGENESIS
- STAT3 Phosphorylation at Tyrosine 705 and Serine 727 Differentially Regulates Mouse ESC Fates
- (2013) Guanyi Huang et al. STEM CELLS
- The fairytale of the GSSG/GSH redox potential
- (2012) Leopold Flohé BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Glutathione catalysis and the reaction mechanisms of glutathione-dependent enzymes
- (2012) Marcel Deponte BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Potential role of signal transducer and activator of transcription (STAT)3 signaling pathway in inflammation, survival, proliferation and invasion of hepatocellular carcinoma
- (2012) Aruljothi Subramaniam et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Celastrol Suppresses Growth and Induces Apoptosis of Human Hepatocellular Carcinoma through the Modulation of STAT3/JAK2 Signaling Cascade In Vitro and In Vivo
- (2012) P. Rajendran et al. Cancer Prevention Research
- Celastrol inhibits proliferation and induces chemosensitization through down-regulation of NF-κB and STAT3 regulated gene products in multiple myeloma cells
- (2011) Radhamani Kannaiyan et al. BRITISH JOURNAL OF PHARMACOLOGY
- Honokiol inhibits signal transducer and activator of transcription-3 signaling, proliferation, and survival of hepatocellular carcinoma cells via the protein tyrosine phosphatase SHP-1
- (2011) Peramaiyan Rajendran et al. JOURNAL OF CELLULAR PHYSIOLOGY
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- (2011) Muthu Shanmugam et al. NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL
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- (2010) Feng Li et al. BRITISH JOURNAL OF PHARMACOLOGY
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- (2010) Bin Peng et al. Molecular Cancer
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