Oleuropein induces apoptosis via abrogating NF-κB activation cascade in estrogen receptor-negative breast cancer cells

Triple negative breast cancer in Asia: An insider’s view

(2018) Chao Wang et al.   CANCER TREATMENT REVIEWS

Modulation of diverse oncogenic transcription factors by thymoquinone, an essential oil compound isolated from the seeds of Nigella sativa Linn

(2018) Muthu K. Shanmugam et al.   PHARMACOLOGICAL RESEARCH

Geraniin suppresses ovarian cancer growth through inhibition of NF-κB activation and downregulation of Mcl-1 expression

(2017) Xue Wang et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

The Therapeutic Potential of PI3K/Akt/mTOR Inhibitors in Breast Cancer: Rational and Progress

(2017) Afsane Bahrami et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

PPARγ Ligand–induced Annexin A1 Expression Determines Chemotherapy Response via Deubiquitination of Death Domain Kinase RIP in Triple-negative Breast Cancers

(2017) Luxi Chen et al.   MOLECULAR CANCER THERAPEUTICS

Sporamin induces apoptosis and inhibits NF-κB activation in human pancreatic cancer cells

(2017) Cuijuan Qian et al.   TUMOR BIOLOGY

Oleuropein inhibits the IL-1β-induced expression of inflammatory mediators by suppressing the activation of NF-κB and MAPKs in human osteoarthritis chondrocytes

(2017) Zhenhua Feng et al.   Food & Function

Breast Cancer Stem-Like Cells Are Inhibited by Diosgenin, a Steroidal Saponin, by the Attenuation of the Wnt β-Catenin Signaling via the Wnt Antagonist Secreted Frizzled Related Protein-4

(2017) G. Bhuvanalakshmi et al.   Frontiers in Pharmacology

Potential role of targeted therapies in the treatment of triple-negative breast cancer

(2016) Lee Yueh Jia et al.   ANTI-CANCER DRUGS

Nimbolide-Induced Oxidative Stress Abrogates STAT3 Signaling Cascade and Inhibits Tumor Growth in Transgenic Adenocarcinoma of Mouse Prostate Model

(2016) Jingwen Zhang et al.   ANTIOXIDANTS & REDOX SIGNALING

A novel 4,6-disubstituted-1,2,4-triazolo-1,3,4-thiadiazole derivative inhibits tumor cell invasion and potentiates the apoptotic effect of TNFα by abrogating NF-κB activation cascade

(2016) Raghu Ningegowda et al.   APOPTOSIS

A novel combinatorial strategy using Seliciclib® and Belinostat® for eradication of non-small cell lung cancer via apoptosis induction and BID activation

(2016) Pei-Shi Ong et al.   CANCER LETTERS

Oleuropein Prevents Azoxymethane-Induced Colon Crypt Dysplasia and Leukocytes DNA Damage in A/J Mice

(2016) Maria Vittoria Sepporta et al.   JOURNAL OF MEDICINAL FOOD

Trisubstituted-Imidazoles Induce Apoptosis in Human Breast Cancer Cells by Targeting the Oncogenic PI3K/Akt/mTOR Signaling Pathway

(2016) Chakrabhavi Dhananjaya Mohan et al.   PLoS One

Bioactive natural products in cancer prevention and therapy: Progress and promise

(2016) Anupam Bishayee et al.   SEMINARS IN CANCER BIOLOGY

Cancer prevention and therapy through the modulation of transcription factors by bioactive natural compounds

(2016) Muthu K Shanmugam et al.   SEMINARS IN CANCER BIOLOGY

Novel Synthetic Oxazines Target NF-κB in Colon Cancer In Vitro and Inflammatory Bowel Disease In Vivo

(2016) Anilkumar C. Nirvanappa et al.   PLoS One

NF-κB in cancer therapy

(2015) Feng Li et al.   ARCHIVES OF TOXICOLOGY

Analysis of the intricate relationship between chronic inflammation and cancer

(2015) Edna Zhi Pei Chai et al.   BIOCHEMICAL JOURNAL

Breast cancer statistics, 2015: Convergence of incidence rates between black and white women

(2015) Carol E. DeSantis et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Isorhamnetin augments the anti-tumor effect of capeciatbine through the negative regulation of NF-κB signaling cascade in gastric cancer

(2015) Kanjoormana A. Manu et al.   CANCER LETTERS

Novel agents and associated toxicities of inhibitors of the pi3k/Akt/mtor pathway for the treatment of breast cancer

(2015) S. Chia et al.   Current Oncology

Oleuropein induces apoptosis via activation of caspases and suppression of phosphatidylinositol 3-kinase/protein kinase B pathway in HepG2 human hepatoma cell line

(2015) CHUN-MEI YAN et al.   Molecular Medicine Reports

Chemopreventive effect of oleuropein in colitis-associated colorectal cancer in c57bl/6 mice

(2015) Elisa Giner et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Nitric Oxide-Releasing Aspirin Suppresses NF-κB Signaling in Estrogen Receptor Negative Breast Cancer Cells in Vitro and in Vivo

(2015) Niharika Nath et al.   MOLECULES

Targeting the PI3K/Akt signaling pathway in gastric carcinoma: A reality for personalized medicine?

(2015) Shikha Satendra Singh   WORLD JOURNAL OF GASTROENTEROLOGY

Caspase Functions in Cell Death and Disease: Figure 1.

(2015) David R. McIlwain et al.   Cold Spring Harbor Perspectives in Biology

Natural Bioactives in Cancer Treatment and Prevention

(2015) Yih-Shou Hsieh et al.   Biomed Research International

γ-tocotrienol inhibits angiogenesis-dependent growth of human hepatocellular carcinoma through abrogation of AKT/mTOR pathway in an orthotopic mouse model

(2015) Kodappully Sivaraman Siveen et al.   Oncotarget

DEAD-box helicase DP103 defines metastatic potential of human breast cancers

(2014) Eun Myoung Shin et al.   JOURNAL OF CLINICAL INVESTIGATION

Oleanane triterpenoids in the prevention and therapy of breast cancer: current evidence and future perspectives

(2014) Nisha R. Parikh et al.   PHYTOCHEMISTRY REVIEWS

Novel Medicines and Strategies in Cancer Treatment and Prevention

(2014) Chih-Hsin Tang et al.   Biomed Research International

Breast cancer statistics, 2013

(2013) Carol DeSantis et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Garcinol, a Polyisoprenylated Benzophenone Modulates Multiple Proinflammatory Signaling Cascades Leading to the Suppression of Growth and Survival of Head and Neck Carcinoma

(2013) F. Li et al.   Cancer Prevention Research

Simvastatin sensitizes human gastric cancer xenograft in nude mice to capecitabine by suppressing nuclear factor-kappa B-regulated gene products

(2013) Kanjoormana A. Manu et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Oleuropein and hydroxytyrosol activate GPER/ GPR30-dependent pathways leading to apoptosis of ER-negative SKBR3 breast cancer cells

(2013) Adele Chimento et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Thymoquinone Inhibits Tumor Growth and Induces Apoptosis in a Breast Cancer Xenograft Mouse Model: The Role of p38 MAPK and ROS

(2013) Chern Chiuh Woo et al.   PLoS One

Clinical and biologic features of triple-negative breast cancers in a large cohort of patients with long-term follow-up

(2012) L. Malorni et al.   BREAST CANCER RESEARCH AND TREATMENT

First Evidence That  -Tocotrienol Inhibits the Growth of Human Gastric Cancer and Chemosensitizes It to Capecitabine in a Xenograft Mouse Model through the Modulation of NF- B Pathway

(2012) K. A. Manu et al.   CLINICAL CANCER RESEARCH

Olive oil oleuropein has anti-breast cancer properties with higher efficiency on ER-negative cells

(2012) Maha H. Elamin et al.   FOOD AND CHEMICAL TOXICOLOGY

Multifaceted link between cancer and inflammation

(2011) Gautam Sethi et al.   BIOSCIENCE REPORTS

Olive Oil and Cancer Risk: an Update of Epidemiological Findings through 2010

(2011) Claudio Pelucchi et al.   CURRENT PHARMACEUTICAL DESIGN

Olive oil intake is inversely related to cancer prevalence: a systematic review and a meta-analysis of 13800 patients and 23340 controls in 19 observational studies

(2011) Theodora Psaltopoulou et al.   Lipids in Health and Disease

Plumbagin inhibits invasion and migration of breast and gastric cancer cells by downregulating the expression of chemokine receptor CXCR4

(2011) Kanjoormana Manu et al.   Molecular Cancer

Targeting Cell Signaling and Apoptotic Pathways by Dietary Agents: Role in the Prevention and Treatment of Cancer

(2011) Muthu Shanmugam et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Butein downregulates chemokine receptor CXCR4 expression and function through suppression of NF-κB activation in breast and pancreatic tumor cells

(2010) Angeline Wei Ling Chua et al.   BIOCHEMICAL PHARMACOLOGY

Hexamethylene Bisacetamide (HMBA) simultaneously targets AKT and MAPK pathway and represses NF-κB activity: Implications for cancer therapy

(2010) Anwesha Dey et al.   CELL CYCLE

Crosstalk of reactive oxygen species and NF-κB signaling

(2010) Michael J Morgan et al.   CELL RESEARCH

Reactive oxygen species in cancer

(2010) Geou-Yarh Liou et al.   FREE RADICAL RESEARCH

Effects of olive oil polyphenols on fatty acid synthase gene expression and activity in human colorectal cancer cells

(2010) Maria Notarnicola et al.   Genes and Nutrition

Redox Regulation of Tumor Necrosis Factor Signaling

(2009) Derick Han et al.   ANTIOXIDANTS & REDOX SIGNALING

4-Hydroxyestradiol Induces Anchorage-Independent Growth of Human Mammary Epithelial Cells via Activation of I B Kinase: Potential Role of Reactive Oxygen Species

(2009) S.-A. Park et al.   CANCER RESEARCH

Anti-proliferative and apoptotic effects of oleuropein and hydroxytyrosol on human breast cancer MCF-7 cells

(2009) Junkyu Han et al.   CYTOTECHNOLOGY

Identification of Throuba Thassos, a Traditional Greek Table Olive Variety, as a Nutritional Rich Source of Oleuropein

(2009) Evagelia Zoidou et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Potential pharmacological control of the NF-κB pathway

(2009) Gautam Sethi et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Akt Determines Replicative Senescence and Oxidative or Oncogenic Premature Senescence and Sensitizes Cells to Oxidative Apoptosis

(2008) Veronique Nogueira et al.   CANCER CELL

Nuclear Factor-κB Activation: From Bench to Bedside

(2008) Gautam Sethi et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Targeting Nuclear Factor- B Activation Pathway by Thymoquinone: Role in Suppression of Antiapoptotic Gene Products and Enhancement of Apoptosis

(2008) G. Sethi et al.   MOLECULAR CANCER RESEARCH

Sensitizing estrogen receptor-negative breast cancer cells to tamoxifen with OSU-03012, a novel celecoxib-derived phosphoinositide-dependent protein kinase-1/Akt signaling inhibitor

(2008) S.-C. Weng et al.   MOLECULAR CANCER THERAPEUTICS

Sodium arsenite induces ROS generation, DNA oxidative damage, HO-1 and c-Myc proteins, NF-κB activation and cell proliferation in human breast cancer MCF-7 cells

(2008) Ruben Ruiz-Ramos et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS