标题
Refining and expanding nonribosomal peptide synthetase function and mechanism
作者
关键词
NRPS, Natural products, Bioinformatics, Discovery, Domain, Mechanism
出版物
JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
Volume 46, Issue 3-4, Pages 493-513
出版商
Springer Nature
发表日期
2019-01-24
DOI
10.1007/s10295-018-02130-w
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Discovery of the Tyrobetaine Natural Products and Their Biosynthetic Gene Cluster via Metabologenomics
- (2018) Elizabeth I. Parkinson et al. ACS Chemical Biology
- Interrogation of Benzomalvin Biosynthesis Using Fungal Artificial Chromosomes with Metabolomic Scoring (FAC-MS): Discovery of a Benzodiazepine Synthase Activity
- (2018) Kenneth D. Clevenger et al. BIOCHEMISTRY
- Biosynthesis of Long-Chain N-Acyl Amide by a Truncated Polyketide Synthase–Nonribosomal Peptide Synthetase Hybrid Megasynthase in Fungi
- (2018) Yang Hai et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Structural basis for backbone N-methylation by an interrupted adenylation domain
- (2018) Shogo Mori et al. Nature Chemical Biology
- The cycloaspeptides: uncovering a new model for methylated nonribosomal peptide biosynthesis
- (2018) Kate M. J. de Mattos-Shipley et al. Chemical Science
- The Colibactin Genotoxin Generates DNA Interstrand Cross-Links in Infected Cells
- (2018) Nadège Bossuet-Greif et al. mBio
- Engineering Bifunctional Enzymes Capable of Adenylating and Selectively Methylating the Side Chain or Core of Amino Acids
- (2018) Taylor A. Lundy et al. ACS Synthetic Biology
- Mechanistic Probes for the Epimerization Domain of Nonribosomal Peptide Synthetases
- (2018) Woojoo Kim et al. CHEMBIOCHEM
- Structural Insight into a Novel Formyltransferase and Evolution to a Nonribosomal Peptide Synthetase Tailoring Domain
- (2018) Janice M. Reimer et al. ACS Chemical Biology
- Characterization of Natural Colibactin–Nucleobase Adducts by Tandem Mass Spectrometry and Isotopic Labeling. Support for DNA Alkylation by Cyclopropane Ring Opening
- (2018) Mengzhao Xue et al. BIOCHEMISTRY
- Structural basis of the nonribosomal codes for nonproteinogenic amino acid selective adenylation enzymes in the biosynthesis of natural products
- (2018) Fumitaka Kudo et al. JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
- Domain-Targeted Metabolomics Delineates the Heterocycle Assembly Steps of Colibactin Biosynthesis
- (2017) Eric P. Trautman et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Diversity of nature's assembly lines – recent discoveries in non-ribosomal peptide synthesis
- (2017) Jennifer A. E. Payne et al. Molecular BioSystems
- Are highly morphed peptide frameworks lurking silently in microbial genomes valuable as next generation antibiotic scaffolds?
- (2017) Christopher T. Walsh NATURAL PRODUCT REPORTS
- Biosynthesis: SAM cycles up for colibactin
- (2017) Steven G Van Lanen Nature Chemical Biology
- Colibactin assembly line enzymes use S-adenosylmethionine to build a cyclopropane ring
- (2017) Li Zha et al. Nature Chemical Biology
- β-Lactone formation during product release from a nonribosomal peptide synthetase
- (2017) Jason E Schaffer et al. Nature Chemical Biology
- Monobactam formation in sulfazecin by a nonribosomal peptide synthetase thioesterase
- (2017) Ryan A Oliver et al. Nature Chemical Biology
- d-Alanylation in the Assembly of Ansatrienin Side Chain Is Catalyzed by a Modular NRPS
- (2016) Guoyin Shi et al. ACS Chemical Biology
- Genome Mining of Amino Group Carrier Protein-Mediated Machinery: Discovery and Biosynthetic Characterization of a Natural Product with Unique Hydrazone Unit
- (2016) Kenichi Matsuda et al. ACS Chemical Biology
- The Role of a Nonribosomal Peptide Synthetase inl-Lysine Lactamization During Capuramycin Biosynthesis
- (2016) Xiaodong Liu et al. CHEMBIOCHEM
- Structures of two distinct conformations of holo-non-ribosomal peptide synthetases
- (2016) Eric J. Drake et al. NATURE
- Synthetic cycle of the initiation module of a formylating nonribosomal peptide synthetase
- (2016) Janice M. Reimer et al. NATURE
- Amino-group carrier-protein-mediated secondary metabolite biosynthesis in Streptomyces
- (2016) Fumihito Hasebe et al. Nature Chemical Biology
- Structural basis of nonribosomal peptide macrocyclization in fungi
- (2016) Jinru Zhang et al. Nature Chemical Biology
- Divergent biosynthesis yields a cytotoxic aminomalonate-containing precolibactin
- (2016) Zhong-Rui Li et al. Nature Chemical Biology
- Deletion of the side chain assembly reveals diverse post-PKS modifications in the biosynthesis of ansatrienins
- (2016) Xiaomei Li et al. RSC Advances
- Critical Intermediates Reveal New Biosynthetic Events in the Enigmatic Colibactin Pathway
- (2015) Zhong-Rui Li et al. CHEMBIOCHEM
- Active site-directed proteomic probes for adenylation domains in nonribosomal peptide synthetases
- (2015) Sho Konno et al. CHEMICAL COMMUNICATIONS
- X-domain of peptide synthetases recruits oxygenases crucial for glycopeptide biosynthesis
- (2015) Kristina Haslinger et al. NATURE
- The structural biology of biosynthetic megaenzymes
- (2015) Kira J Weissman Nature Chemical Biology
- The colibactin warhead crosslinks DNA
- (2015) Maria I. Vizcaino et al. Nature Chemistry
- Biosynthesis of the Anti-infective Marformycins Featuring Pre-NRPS Assembly Line N-Formylation and O-Methylation and Post-Assembly Line C-Hydroxylation Chemistries
- (2015) Jing Liu et al. ORGANIC LETTERS
- Isolation of a Metabolite from the pks Island Provides Insights into Colibactin Biosynthesis and Activity
- (2015) Carolyn A. Brotherton et al. ORGANIC LETTERS
- Two more pieces of the colibactin genotoxin puzzle from Escherichia coli show incorporation of an unusual 1-aminocyclopropanecarboxylic acid moiety
- (2015) Xiaoying Bian et al. Chemical Science
- Identification and catalytic characterization of a nonribosomal peptide synthetase-like (NRPS-like) enzyme involved in the biosynthesis of echosides from Streptomyces sp. LZ35
- (2014) Jing Zhu et al. GENE
- Adenylation and S-Methylation of Cysteine by the Bifunctional Enzyme TioN in Thiocoraline Biosynthesis
- (2014) Ahmad H. Al-Mestarihi et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Comparative Metabolomics and Structural Characterizations Illuminate Colibactin Pathway-Dependent Small Molecules
- (2014) Maria I. Vizcaino et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- New anti-infective cycloheptadepsipeptide congeners and absolute stereochemistry from the deep sea-derived Streptomyces drozdowiczii SCSIO 10141
- (2014) Xiao Zhou et al. TETRAHEDRON
- In Vivo Evidence for a Prodrug Activation Mechanism during Colibactin Maturation
- (2013) Xiaoying Bian et al. CHEMBIOCHEM
- KtzJ-dependent serine activation and O-methylation by KtzH for kutznerides biosynthesis
- (2013) Olga E Zolova et al. JOURNAL OF ANTIBIOTICS
- Glycopeptide antibiotic biosynthesis
- (2013) Grace Yim et al. JOURNAL OF ANTIBIOTICS
- Microbial genome mining for accelerated natural products discovery: is a renaissance in the making?
- (2013) Brian O. Bachmann et al. JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
- A Prodrug Resistance Mechanism Is Involved in Colibactin Biosynthesis and Cytotoxicity
- (2013) Carolyn A. Brotherton et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Analysis of Structure–Function Relationships in the Colibactin-Maturating Enzyme ClbP
- (2012) Antony Cougnoux et al. JOURNAL OF MOLECULAR BIOLOGY
- Structure and noncanonical chemistry of nonribosomal peptide biosynthetic machinery
- (2012) Heather L. Condurso et al. NATURAL PRODUCT REPORTS
- Cyclization of fungal nonribosomal peptides by a terminal condensation-like domain
- (2012) Xue Gao et al. Nature Chemical Biology
- Unusual Activities of the Thioesterase Domain for the Biosynthesis of the Polycyclic Tetramate Macrolactam HSAF in Lysobacter enzymogenes C3
- (2011) Lili Lou et al. BIOCHEMISTRY
- Ralfuranone Biosynthesis in Ralstonia solanacearum Suggests Functional Divergence in the Quinone Synthetase Family of Enzymes
- (2011) Barbara Wackler et al. CHEMISTRY & BIOLOGY
- First Natural Analogs of the Cytotoxic Thiodepsipeptide Thiocoraline A from a MarineVerrucosisporasp.
- (2011) Thomas P. Wyche et al. JOURNAL OF ORGANIC CHEMISTRY
- NRPSpredictor2—a web server for predicting NRPS adenylation domain specificity
- (2011) Marc Röttig et al. NUCLEIC ACIDS RESEARCH
- Glycopeptide biosynthesis in the context of basic cellular functions
- (2010) Evi Stegmann et al. CURRENT OPINION IN MICROBIOLOGY
- Biosynthesis of HSAF, a Tetramic Acid-Containing Macrolactam from Lysobacter enzymogenes
- (2010) Lili Lou et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- An ATP-independent strategy for amide bond formation in antibiotic biosynthesis
- (2010) Masanori Funabashi et al. Nature Chemical Biology
- Conformational Dynamics in the Acyl-CoA Synthetases, Adenylation Domains of Non-ribosomal Peptide Synthetases, and Firefly Luciferase
- (2009) Andrew M. Gulick ACS Chemical Biology
- Crosslinking Studies of Protein-Protein Interactions in Nonribosomal Peptide Biosynthesis
- (2009) Gene H. Hur et al. CHEMISTRY & BIOLOGY
- PKS and NRPS release mechanisms
- (2009) Liangcheng Du et al. NATURAL PRODUCT REPORTS
- A free-standing condensation enzyme catalyzing ester bond formation in C-1027 biosynthesis
- (2009) S. Lin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Crystal Structure of a Molecular Assembly Line
- (2008) Kira J. Weissman et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Characterization of the Azinomycin B Biosynthetic Gene Cluster Revealing a Different Iterative Type I Polyketide Synthase for Naphthoate Biosynthesis
- (2008) Qunfei Zhao et al. CHEMISTRY & BIOLOGY
- Genome Mining for Novel Natural Product Discovery
- (2008) Gregory L. Challis JOURNAL OF MEDICINAL CHEMISTRY
- Thioesterase-Like Role for Fungal PKS-NRPS Hybrid Reductive Domains
- (2008) James W. Sims et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Dynamic thiolation–thioesterase structure of a non-ribosomal peptide synthetase
- (2008) Dominique P. Frueh et al. NATURE
- Crystal Structure of the Termination Module of a Nonribosomal Peptide Synthetase
- (2008) A. Tanovic et al. SCIENCE
- New insights into the first oxidative phenol coupling reaction during vancomycin biosynthesis
- (2007) Nina Geib et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
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