Glycopeptide antibiotic biosynthesis

In VivoStudies Suggest that Induction of VanS-Dependent Vancomycin Resistance Requires Binding of the Drug to d-Ala-d-Ala Termini in the Peptidoglycan Cell Wall

(2013) Min Jung Kwun et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Identifying producers of antibacterial compounds by screening for antibiotic resistance

(2013) Maulik N Thaker et al.   NATURE BIOTECHNOLOGY

Mapping gene clusters within arrayed metagenomic libraries to expand the structural diversity of biomedically relevant natural products

(2013) J. G. Owen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Substituent Effects on the Phenol Coupling Reaction Catalyzed by the Vancomycin Biosynthetic P450 Enzyme OxyB

(2012) Patrick C. Schmartz et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Novel Membrane Protein, VanJ, Conferring Resistance to Teicoplanin

(2012) Gabriela Novotna et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Glycopeptide Sulfation Evades Resistance

(2012) L. Kalan et al.   JOURNAL OF BACTERIOLOGY

Sulfonation of glycopeptide antibiotics by sulfotransferase StaL depends on conformational flexibility of aglycone scaffold

(2012) R. Shi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Self-Resistance and Cell Wall Composition in the Glycopeptide Producer Amycolatopsis balhimycina

(2011) Till F. Schäberle et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

antiSMASH: rapid identification, annotation and analysis of secondary metabolite biosynthesis gene clusters in bacterial and fungal genome sequences

(2011) Marnix H. Medema et al.   NUCLEIC ACIDS RESEARCH

Crystal structure of a phenol-coupling P450 monooxygenase involved in teicoplanin biosynthesis

(2011) Zhi Li et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

The 2.7 Å resolution structure of the glycopeptide sulfotransferase Teg14

(2010) Matthew J. Bick et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Novel Mechanism of Glycopeptide Resistance in the A40926 Producer Nonomuraea sp. ATCC 39727

(2010) G. L. Marcone et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Structural characterization of CYP165D3, a cytochrome P450 involved in phenolic coupling in teicoplanin biosynthesis

(2010) Max J. Cryle et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Crystal Structures of the Glycopeptide Sulfotransferase Teg12 in a Complex with the Teicoplanin Aglycone

(2010) Matthew J. Bick et al.   BIOCHEMISTRY

The Thioesterase Bhp is Involved in the Formation of β-Hydroxytyrosine during Balhimycin Biosynthesis in Amycolatopsis balhimycina

(2010) Sri Mulyani et al.   CHEMBIOCHEM

Structural Characterization of OxyD, a Cytochrome P450 Involved in β-Hydroxytyrosine Formation in Vancomycin Biosynthesis

(2010) Max J. Cryle et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Avoidance of suicide in antibiotic-producing microbes

(2010) Eric Cundliffe et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Tailoring Enzyme-Rich Environmental DNA Clones: A Source of Enzymes for Generating Libraries of Unnatural Natural Products

(2010) Jacob J. Banik et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A vancomycin photoprobe identifies the histidine kinase VanSsc as a vancomycin receptor

(2010) Kalinka Koteva et al.   Nature Chemical Biology

Structure and Function of the Glycopeptide N-methyltransferase MtfA, a Tool for the Biosynthesis of Modified Glycopeptide Antibiotics

(2009) Rong Shi et al.   CHEMISTRY & BIOLOGY

Chimeric Glycosyltransferases for the Generation of Hybrid Glycopeptides

(2009) Andrew W. Truman et al.   CHEMISTRY & BIOLOGY

Cloning and characterization of new glycopeptide gene clusters found in an environmental DNA megalibrary

(2008) J. J. Banik et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA