Structures of two distinct conformations of holo-non-ribosomal peptide synthetases

Identification of genes essential for pellicle formation in Acinetobacter baumannii

(2015) Sarah K. Giles et al.   BMC MICROBIOLOGY

Structure and Substrate Sequestration in the Pyoluteorin Type II Peptidyl Carrier Protein PltL

(2015) Matt J. Jaremko et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Solution Structure of a Nonribosomal Peptide Synthetase Carrier Protein Loaded with Its Substrate Reveals Transient, Well-Defined Contacts

(2015) Andrew C. Goodrich et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

β-Lactam formation by a non-ribosomal peptide synthetase during antibiotic biosynthesis

(2015) Nicole M. Gaudelli et al.   NATURE

Structure of a modular polyketide synthase

(2014) Somnath Dutta et al.   NATURE

Analysis of the linker region joining the adenylation and carrier protein domains of the modular nonribosomal peptide synthetases

(2014) Bradley R. Miller et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Structure determination of the functional domain interaction of a chimeric nonribosomal peptide synthetase from a challenging crystal with noncrystallographic translational symmetry

(2013) Jesse A. Sundlov et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Crystal Structures of the First Condensation Domain of CDA Synthetase Suggest Conformational Changes during the Synthetic Cycle of Nonribosomal Peptide Synthetases

(2013) Kristjan Bloudoff et al.   JOURNAL OF MOLECULAR BIOLOGY

Whole Transcriptome Analysis of Acinetobacter baumannii Assessed by RNA-Sequencing Reveals Different mRNA Expression Profiles in Biofilm Compared to Planktonic Cells

(2013) Soraya Rumbo-Feal et al.   PLoS One

TLSfrom fundamentals to practice

(2013) Alexandre Urzhumtsev et al.   Crystallography Reviews

Structure of PA1221, a Nonribosomal Peptide Synthetase Containing Adenylation and Peptidyl Carrier Protein Domains

(2012) Carter A. Mitchell et al.   BIOCHEMISTRY

Structural and Functional Investigation of the Intermolecular Interaction between NRPS Adenylation and Carrier Protein Domains

(2012) Jesse A. Sundlov et al.   CHEMISTRY & BIOLOGY

Iterative Stable Alignment and Clustering of 2D Transmission Electron Microscope Images

(2012) Zhengfan Yang et al.   STRUCTURE

iMOSFLM: a new graphical interface for diffraction-image processing withMOSFLM

(2011) T. Geoff G. Battye et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structural Basis for Phosphopantetheinyl Carrier Domain Interactions in the Terminal Module of Nonribosomal Peptide Synthetases

(2011) Ye Liu et al.   CHEMISTRY & BIOLOGY

Genetic analysis of surface motility in Acinetobacter baumannii

(2011) K. M. Clemmer et al.   MICROBIOLOGY-SGM

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

A continuous kinetic assay for adenylation enzyme activity and inhibition

(2010) Daniel J. Wilson et al.   ANALYTICAL BIOCHEMISTRY

Nonribosomal peptide synthetases: structures and dynamics

(2010) Matthias Strieker et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Natural Products Version 2.0: Connecting Genes to Molecules

(2010) Christopher T. Walsh et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Conformational Dynamics in the Acyl-CoA Synthetases, Adenylation Domains of Non-ribosomal Peptide Synthetases, and Firefly Luciferase

(2009) Andrew M. Gulick   ACS Chemical Biology

A critical electrostatic interaction mediates inhibitor recognition by human asparagine synthetase

(2009) Hideyuki Ikeuchi et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Structural insights into nonribosomal peptide enzymatic assembly lines

(2009) Alexander Koglin et al.   NATURAL PRODUCT REPORTS

Antibiotics for Emerging Pathogens

(2009) M. A. Fischbach et al.   SCIENCE

Comparative Genome Sequence Analysis of Multidrug-Resistant Acinetobacter baumannii

(2008) M. D. Adams et al.   JOURNAL OF BACTERIOLOGY

Dynamic thiolation–thioesterase structure of a non-ribosomal peptide synthetase

(2008) Dominique P. Frueh et al.   NATURE

Automated macromolecular model building for X-ray crystallography using ARP/wARP version 7

(2008) Gerrit Langer et al.   Nature Protocols

Crystal Structure of the Termination Module of a Nonribosomal Peptide Synthetase

(2008) A. Tanovic et al.   SCIENCE

The Chemical Versatility of Natural-Product Assembly Lines

(2007) Christopher T. Walsh   ACCOUNTS OF CHEMICAL RESEARCH